Healing and Magnesium Author：RSMI109 | Size：2.32 M | View：497 | Page：75Healing and Magnesium > > Urine color: What does it mean? width="100%" > Urine color Possible medical and dietary causes Clear Excess liquids Liver disorders, such as acute viral hepatitis or cirrhosis Bright or neon yellow Vitamin s...
Healing and Magnesium > > Urine color: What does it mean? width="100%" > Urine color Possible medical and dietary causes Clear Excess liquids Liver disorders, such as acute viral hepatitis or cirrhosis Bright or neon yellow Vitamin supplements Dark yellow or gold Dehydration Pink or red Blood in the urine, such as due to kidney or bladder infection or cancer Certain foods, such as beets and berries, and food dyes Some laxatives Orange Side effect of certain medications, such as rifampin, doxorubicin (Adriamycin, Rubex), phenazopyridine (Pyridium) and warfarin (Coumadin) Certain foods and food dyes Dehydration Blue or green Side effect of certain medications, such as amitriptyline and indomethacin (Indocin) Certain foods, such as asparagus, and food dyes Dark brown or tea colored Liver disorders, especially if accompanied by pale stools and jaundice Side effect of certain medications Blood in the urine Certain foods and food dyes Cloudy or murky urine Urinary tract infections Kidney stones Spices and Herbs: Natural Healing Traditions of Mexicoby Elaine K. HarrissMay/Mayo 1998 Home| Mexico | Mexico Travel Services| Mexico NewsSources | MexicoBooks | HealthyTraveling | Spices and HerbsSome of the worlds greatest healing agents have beenderived from simple, native herbs and spices. Mexico offers generationsof traditional natural medicines handed from grandmother to mother to daughter.With this heritage and the rich variety of cultures and landscapes, LatinAmerican families have managed to continue their use of herbs for medicationwithout controversial mandates that we experience in the United States.True that in most families these traditional medicines arefrom lack of accessibility of over-the-counter drugs and prescribedmedications, but who is to say that this is not of more benefit than loss?Studies have shown that the lack of side-effects with natural herbal medicinesoffers an easier healing process for most people. A few examples of Mexicos common healing herbs are: Cilantro (Coriandrum sativum), used primarily as a spice in Mexican dishes, is also valuable as a medicinal tea used for calming anxious children, for stomach cramps, and as a mouth wash for inflamed gums. Epazote (Chenopodium ambrosioides) because of its tenacity and ability to grow in less than ideal conditions is used throughout southern and central Mexico where mothers steep it in milk and sugar and give the resulting "tea" to their children to help rid them of intestinal parasites. It is also known to prevent flatulence when added to your beans ten to fifteen minutes before cooking is complete. Estafiate (Artemisia ludoviciana, frigida), or Wormwood, is used primarily to treat stomach ailments, but may also serve as a deterrent for diarrhea and for menstrual cramps. Additionally it may be used as a bath for rheumatism or to reduce swelling from sprains or as a steam inhalation for sore throat. Yerbanis (Tagetes lucida), or Mexican Marigold Mint, is primarily used as a medicinal tea to calm stomachs and nerves, cure colds, and to alleviate the symptoms of a hangover. It grows throughout central and southern Mexico and is popular with the Tarahumara Indians of Chihuahua and the Huichol Indians of Jalisco and Nayarit who use it in their religious rituals. Yerba Buena (Mentha spicata) or Spearmint, works well as a simple, soothing tea to ease stomachaches, headaches, and childbirth. It is also brewed with cinnamon, clove, and nutmeg to cure a hangover and is a well-known remedy for flatulence. Oregano de la Sierra (Lippia graveolens) or Mexican oregano, a native to rocky slopes, arroyos, and the arid conditions of Mexico and Central America, is good used as a hot tea for coughs and also for indigestion and gas in the stomach. Magnesium Forward: Although this essay was written originally to address the role of magnesium in treating depression, the role of magnesium deficiency as cause of vast other morbidity and mortality is also addressed. This essay is my "notes to myself", and you are welcome to visit and explore what I am finding and to discuss it with me. As much as possible, all research presented is from primary medical research by others. I am just a reporter interested in seeing why things are going wrong in American medicine. I think much is wrong with American medicine, but not American medical science. We need to look into the vast library of medical research to see our paths better, and not wait until medicine catches up. From this research, I am forced to believe that much of what is wrong stems from our practice of eating refined grain products. In centuries prior to the twentieth, bread was the "staff of life" primarily due to its mineral and caloric content. Today, perhaps we need to think of bread and other refined grain products as the "staff of death" due to the absence or near absence of life-sustaining minerals. As you read this essay, please ask yourself if it is actually possible that the entire foundation of medicine is built upon a foundation of quicksand (low magnesium and high calcium)? You may find some answers here. DEPRESSION REALLY SUCKS! It needlessly sucks happiness and joy out of a person and may even suck the life out too if it cant be brought under control. I believe that curing stress- and/or diet-induced depression is extremely simple and quick using magnesium rather than drugs for many people - fortunately! Read my story and check out the facts in the links. Many links are directly to medical articles in the National Library of Medicine (PubMed) and other authoritative sources. You may find my story to be important to you. Remember my point of view that depression, and particularly stress- and/or diet-induced depression, and many other "diseases" discussed below are often symptoms of magnesium deficiency (either directly or indirectly through excess stress) and not psychoses. The National Institute of Health (NIH) reported in 2000 that a sign of magnesium deficiency is depression. NIH defined magnesium deficiency symptoms have three categories: Early symptoms include (one or more) irritability, anxiety (including Obsessive Compulsion Disorder (OCD) and Tourette syndrome), anorexia, fatigue, insomnia, and muscle twitching. Other symptoms include apathy, confusion, poor memory, poor attention and the reduced ability to learn. (NOTE: If this essay appears difficult to understand, consider your magnesium status.) Moderate deficiency symptoms can consist of the above and possibly rapid heartbeat, irregular heartbeat and other cardiovascular changes (some being lethal). Severe deficiency symptoms can include the one or more of the above symptoms and one or more severe symptom including full body tingling, numbness, and a sustained contraction of the muscles, along with hallucinations and delirium (including depression) and finally dementia (Alzheimers Disease). If the NIH knows this, why dont doctors use magnesium to treat depression and other mental (and physical) disorders??? In 1989, C. Norman Shealy M.D., Ph.D. demonstrated that 99% of depressed patients have one or more neurochemical abnormalities; and that depression is a chemical disease as is diabetes, not a psychiatric disease. It seems to me that not using magnesium to treat depression is pure malpractice! We could rebuild and save lives! Magnesium ions are shown involved at the very heart of neural synaptic activity in this figure. Are you magnesium depleted or deficient? See this wonderful quick quiz by Dr. Pricilla Slagle, M.D., a magnesium expert very interested in helping people with magnesium problems. Also, visit Dr. Herbert C.Mansmann, Jr., MD at THE MAGNESIUM RESEARCH LABORATORY, another very interested magnesium expert. Magnesium deficiency is a major risk factor for heart problems and diabetes and many other health issues, including sudden death. "The Magnesium Factor" by Mildred S. Seelig, MD, MPH and Andrea Rosanoff, PhD is an outstanding new book by the worlds leading magnesium researcher and is highly recommended reading for learning how to prevent high blood pressure, heart disease, diabetes, and other chronic conditions. Many of todays "diseases" are actually "symptoms" of magnesium deficiency, and are not diseases. For another eye opener, see this amazing list and thorough documentation of hundreds of "diseases" that are often nothing more than magnesium deficiencies. What would happen to "medicine", pharmaceutical company income, and public health if these "diseases" were treated with magnesium before trying side-effect laden drugs? Wouldnt this approach to improving public health be more ethical? Unfortunately, for space reasons, this essay is restricted to mental health issues reasonably related to depression (and cardiology), but the health risks resulting from magnesium deficiency are very broad and need much exploration. Depression Defined Depression is an extremely common condition that affects more than 1 in 20 people in any one year in Western society. Depression used to be a rare condition, but as our consumption of magnesium has gone down over the last 100 years, or mental health has taken a serious hit as shown here. Depression is one of several hyperemotional states. A sudden loss of interest in life combined with a feeling of worthlessness may be associated with depression. Normally joy, sadness and grief are parts of everyday life. While a short period of depression in our response to daily problems is normal, a long period of depression and sadness is abnormal and is called "clinical depression". Depression can run in families, partly because families tend to eat the same foods and pass from one generation to the next similar eating patterns, and partly through genetics. Concerning genetics, I have found no evidence in the medical literature of a "depression" gene, but much evidence for a search for one. I suspect that the strong genetic component will be found to involve improper or inadequate magnesium metabolism. Depression may be associated with a variety of symptoms, including but not limited to: Persistent sadness and pessimism Feelings of loneliness, guilt, worthlessness, helplessness, or hopelessness Loss of interest or enjoyment in nearly every aspect of life Diminished ability to think or lack of concentration Insomnia or oversleeping Poor appetite associated with either weight gain or loss Fatigue, lack of energy Physical hyperactivity or inactivity Loss of interest in sex Physical symptoms such as headache, backaches, stomach troubles, constipation and blurred vision Anxiety, agitation, irritability Thoughts of suicide or death (90% of suicides result from depression) Slow speech; slow movements Drug or alcohol abuse A drop in school performance Most depressive episodes are triggered by stressful personal event such as lossof a loved one or change of circumstances, and depression over a short periodis a normal coping mechanism. Long-term stress-induced depression often, if notalways, results when magnesium levels fall to dangerously low levels in thebody by biochemical stress reactions discussed below.Magnesium deficiency related depression is a fixable biochemical problem andnot necessarily a physiological problem. Depression can also be due to many other factors such asunderlying disease (particularly hepatitisC), brain chemical imbalances requiring antidepressant drugs of onetype or another, hormonal imbalance (particularly hypothyroidismand lowtestosterone), lowcholesterol, WilsonsDisease, food allergy (particularlygluten intolerance), and adverse reaction to medications, each of whichrequires professional care. Magnesium deficiency is not necessarily the onlycause of depression, but it can be very useful in recovering from depressionbecause the blood and body often become depleted of magnesium in depression,particularly stress-induced or diet-induced depression. Often, depression thatdoes not respond to SSRIs (classical antidepressants) will respond best totreatment with magnesium. Symptomslisted for paying for magnesium serum level tests to detect hypomagnesemia (lowblood levels of magnesium) by a major United States insurance carrier include depression.However, magnesium is an intracellular cation, and its only validmeasurement is through Intracellular spectroscopy testing, orred blood cell (not whole blood or serum) testing. This is because only onepercent of all body magnesium is found in the serum, while the remainder isfound inside cells. Consequently, serum testing, the routine clinical measure,makes as much sense as checking the carburetor bowl of a car to see if gasolineis needed. A huge list of diseases and health conditions meriting magnesiumstatus testing is here. Not too certain what your problem is? If you are interested in knowinggenerally about mental health issues generally, look through the Mental health Net site. If you areinterested in what life as a manic depressive (bi-polar) is like, click here. You cantest your own level of mania on the Goldberg Depression Inventory here,and depression here. MY STORY From early 2000 to summer of 2003, this essay focused upon magnesium glycinateas the preferred source of magnesium. Now, in late summer of 2003, I haveshifted emphasis from magnesium glycinate to magnesium taurate, which appearssuperior to all other forms of magnesium in treating treatment resistantdepression due to its content of taurine (more on taurine here).Other effective magnesium compounds mentioned throughout this essay are rankedwell behind magnesium taurate and are not recommended unless magnesium tauratecan not be obtained. After years of study, I remain truly amazed at thetremendous benefits of magnesium and other nutrients in treating and preventingdepression. In particular, I see magnesium as an important research topic forsurvival considering its limited availability from our Western diets and due toits ability to inexpensively cure and prevent many expensive diseases, lifethreatening or not. As you will see from this essay, our dietary choices andour over consumption of certain foods are contributing to much illness,including depression. Ihave major PRECAUTIONS at this linkconcerning potentially harmful magnesium compounds and at this linkconcerning ineffective compounds of magnesium for treating depression. Forbrevity and simplicity: (a) magnesium oxide and magnesium hydroxide areineffective and (b) magnesium glutamate and magnesium aspartate are potentiallyharmful. I know how bad depression can be, because I spent September of 1999 throughApril of 2000, in a clinical depression that worsened from the beginning. ByChristmas the depression suddenly became much worse, nearly suicidal inintensity, and remained that way for four more months. I had always thoughtthat I was a mild hypo manic-depressive, not a suicidal idiot. In my highs Iwas capable of deep, insightful thought and amplified abilities in generalwhich I considered to be an advantage. Never did I think that things could goso wrong with my biochemistry that it would cause me to have suicidal thoughtsand tendencies. How wrong I was. I had been taking Zoloft (an antidepressant)since 1987 which seemed to take care of my depression. I lived on Zoloft, butby September of 1999, it stopped working - and I knew that something was reallywrong. My depression was preceded by many years and accompanied by major stress fromover-work, treatment responsive depression, anxiety, hypomania, fibromyalgia,infrequent panic attacks, anger, stress, poor diet, overwhelming emotionalfeelings, night time muscle spasms, paranoia, asthma, prickly sensations inhands, arms, chest and lips. I wanted to sleep all day and had trouble gettingup in mornings. Occasionally my lips felt that they were going to vibrate ortingle off my face. I even saw a spider disappear into my arm once. About 10years ago, I had a very painful bout with calcium oxalate kidney stones, arecognized sign of magnesium deficiency. A few weeks before I was hospitalizedin January of 2000, I had very low energy, mental fogginess, depression withstrange suicidal thoughts and I was under enormous stress. Now, I can recognizethese "mental" symptoms as symptoms of magnesium deficiency and/orcalcium toxicity. I wont bother you with the details of my hospitalizeddepressive episode, except to say that I was put on nearly every antidepressantdrug known and had severe side effects to all of them and felt sicker andsicker. None worked. I lost a lot of weight, and I was extremely constipated. Ialso had a cardiac arrhythmia. Being disgusted with the treatment provided, Iwent home. I couldnt work and about all I did was sleep, eat cheese, hardcandy, fatty foods, bread, ice cream, tapioca pudding, drink a lot of milk,consume other bad-for-you high-calcium delicacies, watch TV and read. Maybe Isecretly figured that if I didnt die slowly and agonizingly from depression,maybe I would die quickly with a heart killing diet. My reading preferences are in the biomedical field. At home, I researchedmedical journals, books and everything medical that I could find on depression andmanic depression. I learned nothing of usefulness, at least nothing that mydoctor had not already told me. I did find that certain foods like wheat andhigh carbohydrate diets can trigger dysphoric rage and depression, so it seemedto me that correcting nutritional problems should be beneficial, and thatnutritional research would be worthwhile. On April 12, 2000, I looked like I was dying to several people important in my life. My psychiatrist agreed andtook me off all antidepressant medications and put me on a tiny amount oflithium carbonate (150 mg twice a day). NOTE: At theend of each following section of this essay, I have placed a link concerning my rules for success, andthe affirmation that "Depression is not a psychosis.". Iapologize ahead of time for being terribly redundant. My rules and myunderstanding of mood disorders as a magnesium deficiency are so commonlyignored, that I decided they were too important not to heavily emphasize. Cured with Lithium or Magnesium? Shortly later, I picked up a 1975 copy of Nutrition Almanac, McGraw-HillBook Company, New York, and happened to open it to the magnesium section. I wasinterested to find that magnesium was low in the serum of people who weresuicidally depressed and others who were seriously depressed. The articleindicated that magnesium dietary supplements had been effective in treatingdepression. Also, a person with a magnesium deficiency is apt to be uncooperative,withdrawn, apathetic, nervous, have tremors... essentially lots of neurologicalsymptoms associated with depression. I was fascinated to notice that cardiacarrhythmias, heart attacks and kidney stones were also mentioned as magnesiumdeficiency related. Ah-ha! These looked like good clues, but definitely notconvincing. That same day, I found the next clue in my library. It was in a 1995 textbookin which I had a published article about zinc lozenges and the commoncold. In Handbook of Metal-Ligand Interactions in Biological Fluids- Bioinorganic Medicine, volume 2, Marcel Dekker, Inc., New York, there isa chapter by Durlach et al, entitled "Diverse Applications of MagnesiumTherapy". Its authors assert that in their clinical and open trials theyfound symptoms of chronic magnesium deficiency in neuroses to include anxiety,hyper-emotionality (could this be crying, grieving or other forms ofdepression?), fatigue, headaches, insomnia, light-headedness, dizziness,nervous fits, lump in throat, blocked breathing and respiration, cramps, strongtingling, pricking, creeping feeling on the skin having no real cause, chestpain (either of a cardiac nature or not), palpitations, dysrhysthmias, Raynaudssyndrome, and more including latent tetany, constipation, and myocardialinfarction. Some of these symptoms were stated as occurring as part of panicattacks, sometimes with the feeling of imminent death. In a paperby the same group, Durlach showed that aging was a risk factor for magnesiumdeficiency. In another Durlach article, magnesium deficiency and dementiawere equated as being one and the same. In another paper,Singh et al. showed that magnesium status was inversely associated withprevalence of coronary artery disease. I had a calcium oxalate kidney stone afew years ago and was told that I needed to increase my dietary intake ofmagnesium. I didnt but now wish that I had because it is established thatmagnesium prevents calcium oxalate kidneystones. In some ways, depression can be thought of as an aspect of aging or prematureaging. Perhaps the best web site on the Internet related to anti-aging is the Center for Anti-Aging.Spend much time there, because that semi-medical site shows the close relationshipbetween depression and aging, and premature aging. You will be amazed at theattention given to magnesium. Of significant interest was Durlachs statement that chronic primary magnesiumdeficit affects about 15 to 20 percent of the Western population, while othersources more recently place the deficit much higher at nearly 70 percent. Onereason given for the deficit is that magnesium-rich foods are rich in energy(fattening), and they are being avoided in an effort to maintain weight, andbecause we are eating more junk food void of magnesium. Wow! This magnesium/depression hypothesis is coming together! Just a few monthsprevious to the onset of my depression, I had been hospitalized for chest pain,cardiac dysrhysthmia and an inability to take in more than about 1/5 my normalbreath. The hospital found no cardiac problems, and the internist gave me an IVdrip of magnesium sulfate solution. A few hours later all of those symptomsvanished as rapidly as they had come. What I was beginning to see was thatnearly all illnesses in my adult life were magnesium deficit related. From which foods do we get magnesium? According to my Nutrition Almanac,a cup of peanuts or almonds would satisfy the RDA for magnesium, while only 1/4cup of kelp would be needed. Soy flour, bran flakes, whole wheat, raw brownrice, avocado, wheat bran, shrimp, tuna, Brazil nuts, cashew nuts, sesameseeds, walnuts and collard greens also supply significant dietary magnesium. Inthe audio Bible, Genesis1:29 - "God said, Behold, I have given you every herb bearing seed, whichis upon the face of all the earth, and every tree, in the which is the fruit ofa tree yielding seed; to you it shall be for meat." I marvel at thesimilarity of Biblical teaching to the above list of foods containing largeamounts of magnesium. Succeed! Depression is not a psychosis! NIH Table of Food Sources ofMagnesium The NationalInstitute of Health has prepared the following food table showing thebest sources of magnesium in the U.S. diet. Look at it! They are nearly allhighly fattening foods. I would rather not get fat and just take my magnesiumsupplements to handle my depression problems. The very idea of loading up onthese fattening foods should make anyone depressed. The government is a robotsaying over and over "cut down on fattening foods" for your health!BS! For us manic depressives and depressives, following the NIH dietaryguidelines suggested in the NIH link on keeping magnesium intake low issuicidal, not just because they limit our intake of magnesium, but of otherextremely critical nutrients including taurine, boron and Essential Fatty Acids(EFA) such as the Omega-3 EFAs. Even so, the NIH admits that a sign ofmagnesium deficiency is depression. Even though the NIH list appearsaccurate, it may be misleading for us because many of these foods have muchmore calcium than magnesium. Excess calcium over magnesium inhibits absorptionof magnesium from the diet. A list of foods in this web page having moremagnesium than calcium is here. > Food Milligrams %DV Kelp 100 grams (Warning! very high in glutamate) 760 190 Alfalfa 100 grams 230 58 Avocado, Florida, 1/2 med 103 26 Wheat germ, toasted, 1 oz 90 22 Almonds, dry roasted, 1 oz 86 21 Cereal, shredded wheat, 2 rectangular biscuits 80 20 Seeds, pumpkin, 1/2 oz 75 19 Cashews, dry roasted, 1 oz 73 18 Nuts, mixed, dry roasted, 1 oz 66 17 Spinach, cooked, 1/2 c 65 16 Bran flakes, 1/2 c 60 15 Cereal, oats, instant/fortified, cooked w/ water, 1 c 56 14 Potato, baked w/ skin, 1 med 55 14 Soybeans, cooked, 1/2 c 54 14 Peanuts, dry roasted, 1 oz 50 13 Peanut butter, 2 Tbs. 50 13 Chocolate bar, 1.45 oz 45 11 Bran (pure), 2 Tbs 44 11 Vegetarian baked beans, 1/2 c 40 10 Potato, baked w/out skin, 1 med 40 10 Avocado, California, 1/2 med 35 9 Lentils, cooked, 1/2 c 35 9 Banana, raw, 1 medium 34 9 Shrimp, mixed species, raw, 3 oz (12 large) 29 7 Tahini (from sesame seed), 2 Tbs 28 7 Raisins, golden seedless, 1/2 c packed 28 7 Cocoa powder, unsweetened, 1 Tbs 27 7 Bread, whole wheat, 1 slice 24 6 Spinach, raw, 1 c 24 6 Kiwi fruit, raw, 1 med 23 6 Hummus, 2 Tbs 20 5 Broccoli, chopped, boiled, 1/2 c 19 5 *DV = Daily Value. DVs are reference numbers based on the Recommended Dietary Allowance (RDA). They were developed to help consumers determine if a food contains very much of a specific nutrient. The DV for magnesium is 400 milligrams (mg). The percent DV (%DV) listed on the nutrition facts panel of food labels tells adults what percentage of the DV is provided by one serving. Even foods that provide lower percentages of the DV will contribute to a healthful diet. Wow! I am lucky to be alive! My diet had excluded all magnesium richfoods for months. I wonder if people who go on diets delete these criticalfoods from their diet, start to feel a bit low, and rightfully decide to forgetdieting. It is well known that some people must eat fattening foods simply tofeel well. Is magnesium demand from fattening foods the link between fat peopleand depression avoidance? I know that I am not as hungry using magnesiumsupplements. Actually, I think the cure for hunger is magnesium, because thefoods (mainly wheat) that used to be our main source of magnesium and othernutrients are no longer good sources for them. A few days after digesting what I had learned, I checked MedLine for some backup. I looked up"magnesium" AND "depression". Sure enough it was there. Calcium/magnesiumimbalances with magnesium being low were found in depressed patients thathad attempted suicide. Other articles supported the concept too. For example,high serum and cerebrospinal fluid calcium / magnesium ratios were found inrecently hospitalized acutelydepressed patients. The further I looked on the web, the more excitingand proliferate the became - which, hopefully, is reflected in this page.Another book in my library, The Dictionary of Minerals, ThorsonsPublishing Group, New York, point-blank read, "Therapy with magnesium hasbeen used to treat ...mental depression...". Magnesium has recently beenmedically demonstrated to reduce severetherapy resistant mania. That was enough evidence for me. That same dayI purchased magnesium glycinate, a non-toxic dietary supplement found in alocal health food store. How much should I take each day? Was it safe? I reallydidnt know and didnt much care. I made a decision to start out with about 3times the 400 mg/day RDA for magnesium, with 400 mg in the morning, 400 mg midafternoon and 400 mg at bedtime. I used Carlsonschelated magnesium glycinate (200 mg magnesium elemental) product. I was anoptimist by this time so I bought 3 bottles. What did it taste like? To me the first few times I used magnesium glycinate ittasted strangely metallic. But taking it with milk it didnt taste metallic atall. This is an important observation that merits explanation. There arechemicals in milk fats and other food fats that bind magnesium and otherbioactive minerals to biologically inactive state. That may be a reason whyfatty foods are bad for the heart. One might consume enough magnesium tofulfill the RDA, but if the magnesium is bound so tightly to a stearate oroleate that it is non soluble and is excreted through the feces without beingabsorbed into the blood, what good is it? What happens to the heart? Heartattack! I think this is why some in the FDA thinkthe RDA for magnesium should be raised to about 900 mg per day. Other peopleusing magnesium glycinate have not noticed any strange metallic taste. Within a few days to a short week, I felt remarkably better, my depressionlifted noticeably, but I was getting a bit of diarrhea. Yeah! I didnt needthat damned lithium corkscrew anymore!! (just kidding). Oh, the taste of thosetablets! I needed some coated magnesium glycinate tablets. Actually, the tastewas bad during the first few weeks only, after that the taste was notnoticeable. Who knows what that means. Within a week to 10 days of starting magnesium, I felt close to being well. Ilooked so well, that my psychiatrist thought I looked better than he had everseen me. One interesting fact from The Dictionary of Minerals is thatlithium intake is associated with an increase in magnesium, calcium andphosphate blood serum concentrations. A possible explanationfor these findings is that Li+ displaces Mg2+ fromintracellular binding sites. As I improved, I lowered my dosage of magnesium tofind the best dosage for me. I lowered it too much and symptoms rapidly cameback. Eventually, I stabilized the dosage at four 200-mg elemental magnesium(as magnesium glycinate) tablets a day. Four hundred mg is the RDA formagnesium for men. Succeed! Depression is not a psychosis! June 7, 2000 My depression is completely, totally, absolutely gone, gone, gone! I am activeand can function mentally, emotionally, and physically at my best again. Myvision and bowels also returned to normal - finally. I consider myself to beback to my good old normal self - although my critics will never admit that Iam normal and have never been normal. Whatever normal is. Yet, a strangeanxiety that the depression would return remained unabated. What caused my rapid recovery after being a treatment resistant, non-responderfor many months? Did going off those antidepressant meds cause it? Was it myimagination? Would I have gotten well anyway? Was it just the lithium? Iseriously doubt it. My bet is on repletion of magnesium, both by dietarysupplementation and action by lithium in increasing blood serum levels ofmagnesium. I can now see that my diet has been deficient in magnesium foryears. My diet did not include high-in-magnesium foods listed above. Worse, Ihad been on a magnesium depleting diet from eating fatty foods and ingestingtoo much calcium. If I hadnt realized my magnesium problem, I probably wouldhave died of a heart attack, like these guys warn. I repletedmy body with magnesium, but did not use a great excess of magnesium as suchmight be toxic. If you have time, search the above links depressionlinks, and do a search or two for "depression","suicide" and "serotonin". When I conducted a mini search,I was overwhelmed with relating magnesium deficiency with mental illness. Succeed! Depression is not a psychosis! Stress as Ultimate Cause ofDepression If you are a medical or science type you might like to read Mechanisms of Action on theNervous System in Magnesium Deficiency and Dementia. One paragraph inthis link is so important that I quoted it here: "Although a neurosispattern due to magnesium deficiency is frequently observed and simply curedthrough oral physiological supplementation, neuroses are preeminentlyconditioning factors for stress (thus increasing demand for magnesium).Neuroses may therefore very frequently produce secondary magnesium depletion.They require their own specific anti neurotic treatment and not mere oralmagnesium physiological supplementation, but both genuine forms of neurosis dueto primary neural magnesium deficiency and magnesium depletion secondary to aneurosis may exist. These two conditions may be concomitant and reinforce eachother. In these stressful patients it may be difficult to establish the primacyof one or the other. In practice, physiological oral magnesium supplements maybe added to psychiatric treatments, at least at the start." Iinterpret this to mean that magnesium alone can prevent stress from resultingin neuroses. Stressintensifies release of two major classes of "stress hormones", thecatecholamines and corticosteroids, which normally greatly increase survival ofwell animals when their lives are threatened. Catecholaminesare chemically similar small molecules derived from the amino acid tyrosine.The major catecholamines are dopamine, norepinephrine, and epinephrine (oldname: adrenalin). Dopamine is a neurotransmitter (a chemical used to transmitimpulses between nerve cells) found mainly in the brain. Norepinephrine is theprimary neurotransmitter in the sympathetic nervous system (controls the"fight or flight" reaction) and is also found in the brain.Epinephrine is not only a brain neurotransmitter, but also a major hormone inthe body. Epinephrine is secreted from the adrenal medulla in response to lowblood glucose, exercise, and various forms of acute stress (in the latter case,the brain stimulates release of the hormone). Epinephrine causes a breakdown ofglycogen to glucose in liver and muscle, the release of fatty acids fromadipose tissue, vasodilation of small arteries within muscle tissue, andincreases the rate and strength of the heartbeat. All of the catecholamines aremetabolized by their target tissues or by the liver to become inactive substancesthat appear in the urine: For example, dopamine becomes HVA, norepinephrinebecomes normetanephrine and VMA, and epinephrine becomes metanephrine and VMA.Consequently, a urine test for elevated catecholamines is both simple andavailable. If you want to test your brain neurotransmitters, you canget them tested by using a neuroscience test kit supplied by local physicians.To find a local physician that tests neurotransmitters, contact NeuroScience, Inc. Corticosteroidsare group of natural and synthetic analogues of the hormones secreted by thehypothalamic-anterior pituitary-adrenocortical (HPA) axis, more commonlyreferred to as the pituitary gland. These include glucocorticoids, which areanti-inflammatory agents with a large number of other functions;mineralocorticoids, which control salt and water balance primarily throughaction on the kidneys; and corticotropins, which control secretion of hormonesby the pituitary gland. They have been thoroughly researched and developed asdrugs in the treatment of many diseases. Corticosteroids are used toprovide relief for inflamed areas of the body. They are extremely strong drugs.They lessen swelling, redness, itching, and allergic reactions. They are oftenused as part of the treatment for a number of different diseases, such assevere allergies or skin problems, asthma, arthritis and certain cancers andleukemias. They have many well-known sideeffects. Whenmagnesium deficiency exists, stress paradoxically increases risk ofcardiovascular damage including hypertension, cerebrovascular and coronaryconstriction and occlusion, arrhythmias, sudden cardiac death (SCD), asthma,anxiety and depression. Dietary imbalances such as high intakes of fat, sodiumand/or calcium (Ca) can intensify inadequacy of magnesium, especially underconditions of stress. Thus, stress, whether physical (i.e. exertion, heat,cold, trauma - accidental or surgical, burns), or emotional (i.e. pain, anxiety,excitement or depression) and dyspnea (difficulty in breathing) as in asthmaincreases need for magnesium. Magnesium deficiency intensifies adversereactions to stress that can be life threatening. Such reactions are mediatedby excess release of the stress hormones, catecholamines and corticosteroids,which are increased by low magnesium and high calcium levels, and which furtherlower tissue magnesium in a feed back fashion, and suppress testosteroneproduction. Testosteroneproduction may or may not return upon replenishing magnesium. If it does notreturen, low testosterone can be an additional source of depression, andtestosteron creams, shots and pills are available. The creams are definitelythe least likely to produce side effects. Shots and pills of testosterone canresult in weird side effects that that stimulate dangerously high female sexhormone production in men, which requires a female sex hormone suppresanttreatment such as daily tablets of Arimedex. You can end up with more problemsthan before, thus they are prescription-only items. More on the consequences of magnesium deficiency on the enhancement of stressreactions; preventive and therapeutic implications is hereand in the following figure. Genetic differences in magnesium utilization mayaccount for differences in vulnerability to magnesium deficiency anddifferences in body responses to stress. There are so many stressors in ouractive lives that adversely affect magnesium reserves; it is a miracle that wecan live on our puny magnesium deficient diets without vastly more cardiac andpsychiatric problems. Magnesium is a required nutrient for people to handle stress in general and stress in neuropsychiatricdisorders. Not getting sufficient dietary or supplemental magnesiumduring medical treatment for stress related disorders such as anxiety anddepression is bound to fail. A short and easy to read summary of magnesium andits stress relief action is presented hereby Dr. Leo Galland. He points out that stress depletion of magnesium is oftenso intense that dietary sources are insufficient, and supplementation isrequired. Measure your level of stress here.These effects and aggressive behavior are easily observed in the mousemodel. Magnesium is now marketed as an anti stress mineral.Stress, diuretics, fluoride, refined flour, chemotherapy, too much sugar,antibiotics, large amounts of protein, and high fat foods decrease absorptionof magnesium, as do foods high in oxalic acid (mainly fresh spinach andpossibly tea in excess) which deplete magnesium in the body, which in turnslowers ones resistance to stress and depression (a feedback loop). Overweightand obese people are usually low in magnesium, a mineral necessary tometabolize (burn) fat. People working outside in high temperatures and highhumidity often become magnesium deficient and have stress related problems. What blows my mind is that there has already been an extraordinary amount ofwork collecting data that shows magnesium to be a profoundly important nutrientin preventing and treating hundreds of illnesses and conditions, particularlythose illnesses related to stress. It seems that magnesium deficiency in ourdiet is responsible for many forms of bad health and early death. Dont take myword for it, rather visit Paul Masons site and see his huge list of magnesium treatable disorders. Also,the Health-Worldweb site has a growing but still incomplete list of magnesiumdeficiency symptoms, which include (alphabetically) acute heart attacks,agoraphobia, anxiety, angina pectoris, asthma, back aches, breast tenderness,cardiac arrhythmias, chronic fatigue syndrome, cant take a deep breath,carbohydrate craving (especially of chocolate) and carbohydrate intolerance,chest tightness, chronic cardiovascular disease, chronic fatigue syndrome,coronary artery disease, cramps, depression, diabetes, difficulty swallowing,eclampsia of pregnancy, feeling uptight, frequent sighing, epilepsy, headaches,high blood pressure, hyperactivity, insomnia, jaw joint (TMJ) dysfunction, lumpin the throat-especially provoked by eating sugar, menstrual cramps, musclesoreness, muscle tension, mitral valve prolapse, musculoskeletal disorders,neck pain, numbness, palpitations, panic disorder, pre-eclampsia, premenstrualirritability, photophobia, panic attacks, restlessness with constant movement,salt craving, tingling, twitches, urinary spasms, zips, zaps and vibratorysensations. Iremain amazed and perplexed that magnesium deficiency remains, for the mostpart, ignored, neglected, and forgotten. There is one medical journal MagnesiumResearch that reports the subject very well, but it is a very difficultjournal to find in nearly all medical libraries. It is the official organ ofthe International Society for the Development of Research on Magnesium. Theirfirst publication date was July, 1988, which makes it a johnny-come-latelyamong medical journals. The publisher is John Libbey and Company in London.Typically, magnesium researchers find that their work finds no interest byother journal editors, and they end up submitting their work to MagnesiumResearch simply to get it published, where it is totally ignored byestablishment medical doctors and, until recently, remained the subject ofacademic curiosity. Fortunately, independent-minded physicians and citizens canresearch the National Library of Medicines PubMed index andfind these precious life-sustaining journal articles. Paul mason is trying tobring much original research on magnesium and health to the Internet. The fulltext of many vital magnesium and health articles can be directly viewed at thisvital link. It seems to me that byignoring these magnesium deficiency disorders, that medicine has a guaranteedretirement fund. What do I mean? Look at the above list, and other similarlists carefully and you will see that much of medicine is dedicated todeveloping medications for, and treating these specific symptoms and nottreating the underling cause (magnesium deficiency). Consequently, patientsremain ill and return to doctors offices for more expensive pharmaceuticaldrugs. Folks, billions of dollars of Big Pharma drug company income andphysician income is at stake! Be warned! Can I be so obtuse as to say that magnesium supplementation had nothing to dowith my recovery? Can I be so callous as to not recommend magnesium to otherswho are suffering from depression, bi-polar disorder, or any of the anxietyrelated symptoms listed above? Or any of the symptoms of magnesium deficiencylisted here? Duh!!! I am positive that all suffering from clinical depression want relief - NOW! Nowaiting for a med to kick in 4 to 8 weeks! You want it now!!! However, withoutsufficient magnesium, recovery will most likely be very difficult andprolonged. Succeed! Depression is not a psychosis! January 19, 2001 Update andMiscellaneous Musings Looking back over the last year, I now realize that the increases in lithiumthat I was prescribed (a gradual increase from 300 to 1050 mg lithium carbonateper day) was associated with progressive reductions in feeling of well being(sort of a placid zombie-like feeling) and pending damage to thyroid function(excess lithium causes hypothyroidism). On December 5, 2000, I decided that itwas imperative for me to stop lithium because I did not want to have to bedependent upon thyroid extract for the rest of my life due to the toxicity oflithium. Even though lithium is a mineral element, it is not found in the humandiet except in trace amounts (which are related to even temperament). However,magnesium is a vital to life essential human nutrient. I.E. there is no RDA forlithium (or any drug), but there is for magnesium! Actually, lithium is a drugthat is being used to substitute for a nutrient, magnesium! Howtricky of those docs! What a way to drum up business! Surprisingly, I began to feel better, even better than I felt in June when Ifirst started taking low-dose lithium and high-dose magnesium. After severalmonths off of lithium, people say I look ten years younger. I feel much sharperand my mental capabilities have returned to what is normal for me. I hope thatI will never again take lithium. I now strongly suspect that the mainbiochemical function of lithium is to raise magnesium levels in the blood asmentioned above, with the mental benefit coming not from lithium but fromlithium induced increased magnesium blood levels. This idea could account forthe 40 percent failure rate of lithium in preventing future depressive episodes.That is to say, if dietary magnesium intake is so low that not even lithium canreturn it to normal levels, then one succumbs to depression or other magnesium deficiency disorders. I remember meeting people (in group therapy classes and elsewhere) that lookingbackward seem likely to have been magnesium deficient. I remember a brightyoung lady that was terribly suicidal. She was totally resistant to all knownantidepressants. She was so thin that she was nearly skin and bones andobviously was malnourished. She wanted to commit suicide so badly that she wasunder constant supervision. I cant help but wonder if she was misdiagnosed,meaning that she was severely, gravely magnesium depleted. I remember meetingmany other people who were depressed; one was a single female registered nurse,who was overwhelmed by her stressful hospital duties and her desperate familychild care situation. I remember a lovely young suicidal woman whose favoritetune was the theme from M*A*S*H. Apparently, she had no idea of the lyrics tothe song "Suicideis Painless". She had been pounding out that song on piano foryears. I wonder if she would have been there had her favorite song beensomething else. A 40ish man who could no longer accept that he was, in hisopinion, a failure in his business. A lawyer who couldnt handle furtherdomestic abuse. An internationally acclaimed scientist and editor who wasoverwhelmed by his time-line oriented job. Young children who were sad all ofthe time for no apparent reason, even if they were given all the toys theywanted. There was a young gay who desperately didnt want to be gay. Each ofthese people, and I suspect most depressives, share one thing common in theirlives. STRESS!Magnesium deficiency can be brought on by diet too. I know a wonderful younglady who felt that she was too fat for her husband and went on a 1-monthstarvation diet. She lost enough weight, but became extremely magnesiumdeficient; and developed very difficult to treat multiple cardiac anddepression symptoms causing enormous stress in her life. The strange part aboutstress is that magnesium deficiency and stress reinforce and build upon eachother, resulting in a difficult to manage, unstable downward spiral. Succeed! Depression is not a psychosis! FURTHER RESEARCHGovernmentCensorship of this Page This section addresses why certain words (prevent, diagnose, mitigate, treatand cure) are crossed out in this page with substituted words (in bold)following them. On November 6, 2004, a State Food and Drug Investigator for theTexas Department of State Health Services, previously the Texas Department ofHealth, in a routine annual inspection of my business, Eby Pharma LLC, foundviolations of federal law as follows: "A review of the firms web site,http://www.coldcure.com, showed that the web site promotes CardiovascularResearch Ltd., Magnesium Taurate, 60 capsules, as a product that is intended toprevent, diagnose, mitigate, treat, or cure a disease (disease claims). This isnot an all-inclusive review of the web site and the products that the firmmarkets. For example the web site includes the following information:"...magnesium taurate is the preferred forms of magnesium for treatingdepression..." and "...magnesium taurate also is wonderful in helpingto prevent the diarrhea normally resultant from high-does magnesium..."and "...this is also the form of magnesium best for heart and brainhealth...". I promised the State of Texas investigator that I would correct this page by 1/6/05. OK. No big deal, or is it? How have we as a nation come to legally forbid anyreference to "nutrients" as being able to prevent, diagnose,mitigate, treat and cure any disease? I am no legal expert, but a friend ofmine, John Hammell, owner of the InternationalAdvocates of Health Freedom is a world-class expert and witness on whatis going on in the Federal government concerning health freedom in the United States. I asked John the following questions: John, why has there been no (apparently) effort to overturn DSHEA on groundsthat it is overly broad? Seems to me that the US has often reversed"overly broad" laws that are not in the public interest. Seems to methat any law that would be in direct opposition to truth would be illegal too.Seems to me that someone needs to attack laws that make it illegal to claimthat a nutrient can not be claimed to cure a nutritional deficiency disease. Tosay that nothing except a drug can cure, treat, prevent or diagnose a diseaseis "overly broad" because nutritional deficiency can not be cured,treated or prevented by anything except a nutrient. Doesnt make any sense tome that laws like this have not been attacked. Any comments?" John responded with these words: "DSHEA was passed in direct response toan FDA rule making effort called "The Dkykstra Report". The DkykstraReport was an Advance Notice of Proposed Rule making that showed exactly whatFDA intended to do to DESTROY the dietary supplement industry in America, andthey had a congressional mandate through the Nutrition Labeling and EducationAct of 1990 to do just that. NLEA was a stealth bill that was rammed throughthe House at High Speed during the summer when most people were on vacation. Ididnt even know about it til August of 1989 when I jumped in with both feet inan effort to defend consumer access to dietary supplements. By the time I wasaware of the bill, it was on its way to the Senate like a guided missile aimedstraight for the heart of the dietary supplement industry. It would have hadthe exact same effect as Codex still could have unless we pull off a miracleand kill ratification in July through the last ditch campaign we areorganizing. (Note: This may happen! CODEX dealt setbackin June of 2005!) When I jumped into the fray to try to kill the NLEA, I wasshocked and stunned to learn that the National Nutritional Foods Assn (NNFA)(the biggest vitamin trade association and the one which about half the healthfood stores belong to) was FOR this horrible bill. At the time, I was unawarethat they were not enforcing their conflict of interest disclosure bylaw suchthat they were allowing pharmaceutical companies to be amongst theirmembership. NNFA didnt switch their position on this bill and turn against ittil it was too late to stop its passage. I and millions of other people foughtwith every ounce of strength we had to try to kill it in the Senate, but it hadtoo much momentum to stop. We failed, but we at least curbed some of its worstexcesses, and we passed DSHEA as additional protection. No piece of legislationis perfect, any piece of legislation involves compromises due to its being shapedby a real diverse group of people including those on the other side. Ourbiggest opponents during those days were Henry Waxman and John Dingle. Theyboth inserted language into DSHEA that to this day is causing us problems. WhenMilton Bass, JD; Clinton Ray Miller, Gerald Kessler of Natures Plus, and Iattempted to rectify some of the bigger problems found in DSHEA by introducinglegislation that could have filled some of the more onerous holes, we didntget far at all because we were shot down by the pharma dominated vitamin tradeassociations and also by a controlled opposition group called Citizens forHealth. I cant recall the bill number now, its been so many years, but youllfind it on the scroll bar at http://www.iahf.comto this day, I havent removed it. (The bill we were unable to pass that wouldhave filled some of the worst holes in DSHEA.) Trojan Horse language wasinserted into DSHEA by a 5th column group led by controlled opposition group"Citizens for Health." At the time, CFHs biggest financial backerwas Natures Way. Natures Way was part of a coalition called the"European-American Phytomedicines Coalition" which was activelyattempting to harmonize US to German law. They were operating in the US and Canada via two controlled opposition groups Citizens for Health in the USA , and Canadian Coalition for Health Freedom in Canada. IAHF was the sole voiceattempting to expose both groups and I had death threats and constant threatsof legal trouble for my efforts to expose them and for trying to stop CODEX.DSHEA does allow the making of structure function claims for dietarysupplements. While not full fledged health claims, we also won a firstamendment victory via Pierson v Schalala that should allow for the making offull health claims except the Supreme Court has refused to hear an additionalcomplaint brought by Pierson that FDA refuses to obey the law. Against thisbackdrop of FDA refusing to obey current US dietary supplement laws we have theFDA violating US law at Codex meetings in Germany to set us up forharmonization of our laws to outrageously restrictive international standards.IAHF is going to be sending out an updated alert on this in the next few days.In the meantime, please see Suzanne Harris latest article on Codex at http://www.thelawloft.com Were ina desperate race against the clock. Due to our membership in the WTO, were nolonger living in America. For all intents and purposes, America no longerexists because Congress lacks the political will to get us out of the WTO orthe UN and Codex is rolling on us like a runaway freight train with very fewpeople even aware of its existence or the threat it poses due to spin thatsbeen done against my message for the past several years. Were hoping to pullof a miracle. Stay tuned. A new alert is coming very soon. JohnHammell, IAHF Hummm. OK, that is a fine history of what happened, what is happening and whatwill likely happen. To sum it up in a nutshell, we are loosing our freedom ofspeech and our freedom of press and the publics right to buy and sell healthyproducts, perhaps mainly to continue our 15% GDP tithe to Big Pharma(pharmaceutical companies). As you read this article remember what is actuallygoing on in America, and be warned. For a brief overview of the law, read DIETARY SUPPLEMENTHEALTH AND EDUCATION ACT OF 1994 and for a full review of this mattersee the FDAs Dietarysupplements review page. Click here for a briefreview of CODEX within this page. Homeopathic Uses for Magnesium Even though the Texas Department of Health doesnt like magnesium taurate as acure for depression, magnesium has a long record of use as a treatment for manydifferent disorders in homeopathy, including depression. For example magnesiumchloride (Magnesia Muriatica),magnesium carbonate (MagnesiaCarbonica), magnesium phosphate (Magnesia Phosphorica),magnesium sulfate (MagnesiaSulphurica) are all listed for use in treating the many disorders(click on item of interest in left-hand columns). However, if we want to lookonly at "MIND", then magnesium chloride (Magnesia Muriatica) islisted as being suitable for treating: MIND mind; aversions, dislikes; company; aversions, dislikes; indolence, aversion to work; aversions, dislikes; indolence, aversion to work; evening; aversions, dislikes; aversion to mental work; aversions, dislikes; to being spoken to; behaviour; kleptomania; steals dainties; behaviour; makes noises; growling like a dog; behaviour; shrieking; during sleep; behaviour; inclination to sit; conversation; dazed; delusions, imaginations, hallucinations, illusions; delusions, imaginations, hallucinations, illusions; creatures and animals; horses; delusions, imaginations, hallucinations, illusions; visions of phantoms, figures, people; sees thieves; delusions, imaginations, hallucinations, illusions; death; sees dead persons; delusions, imaginations, hallucinations, illusions; death; corpse on a bier; mutilated body; delusions, imaginations, hallucinations, illusions; environment and surroundings; clouds; before the fancy; delusions, imaginations, hallucinations, illusions; environment and surroundings; clouds; clouds and rocks as if looking over; delusions, imaginations, hallucinations, illusions; environment and surroundings; is on a journey; delusions, imaginations, hallucinations, illusions; environment and surroundings; strange; familiar things seem strange; delusions, imaginations, hallucinations, illusions; illusions of fantasy; delusions, imaginations, hallucinations, illusions; illusions of fantasy; during heat; delusions, imaginations, hallucinations, illusions; fire; visions of fire; delusions, imaginations, hallucinations, illusions; hears sounds; growling, as of a bear; delusions, imaginations, hallucinations, illusions; hears sounds; noise; delusions, imaginations, hallucinations, illusions; delusions about other people; friends; being friendless; delusions, imaginations, hallucinations, illusions; about self; circumstances; being friendless; delusions, imaginations, hallucinations, illusions; unpleasant; sees mutilated bodies; delusions, imaginations, hallucinations, illusions; visions or presence of phantoms, figures, people; someone is reading after her, which makes her read faster; delusions, imaginations, hallucinations, illusions; visions or presence of phantoms, figures, people; thieves; sees; delusions, imaginations, hallucinations, illusions; desire for open air; desires, wants; to kill; on waking; symptoms follow intense emotions; anger; excitement; excitement; during period; mental exertion; fantasies; of exaltation; fantasies; of exaltation; on reading; emotions, feelings, attitude, disposition; boredom, dissatisfaction (see loathing of life); emotions, feelings, attitude, disposition; cheerful, happy; daytime; emotions, feelings, attitude, disposition; forsaken feeling; emotions, feelings, attitude, disposition; impulsive; capriciousness; emotions, feelings, attitude, disposition; indecisive; emotions, feelings, attitude, disposition; indifference, apathy, etc.; emotions, feelings, attitude, disposition; indifference, apathy, etc.; morning, on waking; emotions, feelings, attitude, disposition; indifference, apathy, etc.; to pleasure; emotions, feelings, attitude, disposition; irritability; emotions, feelings, attitude, disposition; irritability; morning; emotions, feelings, attitude, disposition; irritability; morning; after rising; emotions, feelings, attitude, disposition; irritability; morning; on waking; emotions, feelings, attitude, disposition; irritability; late morning; emotions, feelings, attitude, disposition; irritability; evening; emotions, feelings, attitude, disposition; irritability; after sexual intercourse; emotions, feelings, attitude, disposition; irritability; during headache; emotions, feelings, attitude, disposition; irritability; before period; emotions, feelings, attitude, disposition; irritability; during period; emotions, feelings, attitude, disposition; irritability; on waking; emotions, feelings, attitude, disposition; loathing; emotions, feelings, attitude, disposition; loathing; morning; emotions, feelings, attitude, disposition; mirth, hilarity, liveliness, etc.; morning; emotions, feelings, attitude, disposition; mood; repulsive, bad mood; emotions, feelings, attitude, disposition; morose; morning; emotions, feelings, attitude, disposition; sensitive, oversensitive; emotions, feelings, attitude, disposition; sensitive, oversensitive; to noise; emotions, feelings, attitude, disposition; sensitive, oversensitive; to noise; voices; emotions, feelings, attitude, disposition; sensitive, oversensitive; to reading; emotions, feelings, attitude, disposition; sulky; emotions, feelings, attitude, disposition; unfriendly humour; emotions, feelings, attitude, disposition; unhappy; despair; discouraged; emotions, feelings, attitude, disposition; unhappy; discontent, displeased, dissatisfied, etc.; emotions, feelings, attitude, disposition; unhappy; sadness, mental depression; emotions, feelings, attitude, disposition; unhappy; sadness, mental depression; morning; emotions, feelings, attitude, disposition; unhappy; sadness, mental depression; before eating; emotions, feelings, attitude, disposition; unhappy; sadness, mental depression; eating; emotions, feelings, attitude, disposition; unhappy; sadness, mental depression; during period; emotions, feelings, attitude, disposition; weeping, crying, tearful mood (lamenting); emotions, feelings, attitude, disposition; weeping, crying, tearful mood (lamenting); after eating; emotions, feelings, attitude, disposition; weeping, crying, tearful mood (lamenting); in sleep; home-sickness (see desires home); hysteria; intellectual faculties; impaired thinking; chaotic; intellectual faculties; impaired thinking; difficulty concentrating; intellectual faculties; impaired thinking; confusion; intellectual faculties; impaired thinking; confusion; morning; intellectual faculties; impaired thinking; confusion; on rising; intellectual faculties; impaired thinking; confusion; open air; intellectual faculties; impaired thinking; confusion; after dinner; intellectual faculties; impaired thinking; confusion; after eating; intellectual faculties; impaired thinking; confusion; when lying down; intellectual faculties; impaired thinking; confusion; from mental exertion; intellectual faculties; impaired thinking; confusion; wrapping up head; intellectual faculties; impaired thinking; dull, sluggish; intellectual faculties; impaired thinking; dull, sluggish; morning; on rising; intellectual faculties; impaired thinking; dull, sluggish; in open air; insecure, uncertain, scared; anxiety; insecure, uncertain, scared; anxiety; morning; insecure, uncertain, scared; anxiety; morning; on waking; insecure, uncertain, scared; anxiety; afternoon; insecure, uncertain, scared; anxiety; afternoon; until evening; insecure, uncertain, scared; anxiety; evening; insecure, uncertain, scared; anxiety; evening; in bed; insecure, uncertain, scared; anxiety; evening; in bed; on closing the eyes; insecure, uncertain, scared; anxiety; night; insecure, uncertain, scared; anxiety; night; before midnight; insecure, uncertain, scared; anxiety; open air; insecure, uncertain, scared; anxiety; in bed; insecure, uncertain, scared; anxiety; on closing eyes; insecure, uncertain, scared; anxiety; during dinner; insecure, uncertain, scared; anxiety; after eating; insecure, uncertain, scared; anxiety; burping, belching; insecure, uncertain, scared; anxiety; during fever; insecure, uncertain, scared; anxiety; about health; insecure, uncertain, scared; anxiety; in house; insecure, uncertain, scared; anxiety; while reading; insecure, uncertain, scared; anxiety; before stool; insecure, uncertain, scared; fear; insecure, uncertain, scared; fear; evening; insecure, uncertain, scared; fear; after dinner; insecure, uncertain, scared; fear; after eating; insecure, uncertain, scared; fear; after food; insecure, uncertain, scared; fear; of robbers; insecure, uncertain, scared; frightened easily; starting, startled; like electric shocks; shocks through the body while wide awake; insecure, uncertain, scared; frightened easily; starting, startled; during sleep; insecure, uncertain, scared; frightened easily; starting, startled; during sleep; starting from sleep; perception; time; time passes too slowly; preoccupied; absorbed, buried in thought; introspection; restlessness, nervousness; restlessness, nervousness; evening; restlessness, nervousness; evening; in bed; restlessness, nervousness; night; restlessness, nervousness; night; before midnight; restlessness, nervousness; night; 2 a.m.; restlessness, nervousness; anxious, etc.; restlessness, nervousness; forcing out of bed; restlessness, nervousness; tossing about in bed; restlessness, nervousness; on closing eyes at night; restlessness, nervousness; during heat; restlessness, nervousness; internal; restlessness, nervousness; while lying down; restlessness, nervousness; during period; mental symptoms from sexual excesses; talking, conversation; aversion to answering; talking, conversation; aversion to answering; morning; talking, conversation; contrary (see obstinate, irritable); talking, conversation; obstinate; talking, conversation; dislike of talking, desire to be silent, taciturn; talking, conversation; dislike of talking, desire to be silent, taciturn; morning; talking, conversation; of others; talking, conversation; in sleep; thoughts (see preoccupied); thoughtful; unconsciousness; unconsciousness; evening; when lying down; unconsciousness; after eating; unconsciousness; while lying down; Consequently, to the regulators that think that magnesium is a "new"drug, I say they are wrong. Magnesium has been around much longer than they,and humans have recognized it as treatment for many disorders and diseases muchlonger than the Food and Drug Administration and its lackeys have been inbusiness. Fortunately, The Congressman who wrote the FDA law, the Pure Food andDrug Act of 1939, was a homeopathy supporter named Sabath, from Illinois, andhe made certain that homeopathy would remain legal. Consequently, anygovernmental regulator that says that we can not make drug claims for magnesiumas a treatment, means of curing, or preventing depression and a wide variety ofrelated mental condition is on legally shaky grounds. All we have to do is usethe proper Latin words! Back to My StoryBackto my history and how I learned to cure my depression. When I purchased myfirst bottle of magnesium glycinate, it was not from intelligence that I chosethat particular compound of magnesium. It was just what was available on theshelf at the store I visited. After considerable research, I found that thestore provided the second best form of magnesium that I could have chosen totreat depression. Only magnesium taurate (a form of magnesium that decreaseschances of diarrhea) is superior to all other forms of magnesium. Both glycineand taurine have been used to effectively treat depression. Also taurine (theligand in magnesium taurate) has been shown to be low or absent in 100 percentof people with depression and chronic pain according to Shealy. I quit taking and quit recommending magnesium glycinate because glycine, in thedoses taken and while taken for a protracted period of time, will damage itsdelicate balance with another amino acid, taurine. Taurine is vital to mentaland cardiac health and must not be disturbed, while glycine is ubiquitous andappears highly unlikely to be bothered by too much taurine. For example, dietswith up to 1% as taurine had no adverse effect on test animals. Long term highdoses of glycinate may cause cardiac arrhythmias, and will never allow totalrecovery from depression or other mood disorders. However, most people willfind that magnesium glycinate works miracles for them in the short-term. Also,both magnesium and taurine have been proven to be low in depression in about80% and 100% of depression cases respectively. Read Shealys article starting here. See sentenceimmediately before the Discussion section. This does not mean magnesiumglycinate is harmful in the short- or near-term, it just means one shouldntuse it year in and year out, and it must be IMMEDIATELY stopped if sideeffects, particularly cardiac arrhythmias (PACs) occur. Taurine is the antidoteto many cardiac problems. See this page for thefirst and only scientific discussion on how taurine prevents and treatsexperimental extra systoles (pre atrial contractions PACs) and many otherserious heart conditions. Glycine (the second component of magnesium glycinate) chelates (removes)mercury from the body, and may be superior to even magnesium taurate for peoplewith heavy metal poisoning in the short- or near-term. Citric acid and cysteinealso remove mercury and appear safer for long term use than glycine. The firststability constants for glycine, cysteine and citric acid are in the log 10 to log14 range, which are vastly stronger bindings than can be broken by anynatural biology or chemistry event occurring in the body. Glycine is anon-essential amino acid, but for people with mercury poisoning, it, cysteineand citric acid may be highly important. Because of these amazing chelating,sequestering or binding powers, if they reacted with mercury in any form in thebody, they should be able to bind them much more tightly, making mercurybiologically unavailable in the body. Perhaps, consumption of large amounts ofthese amino acids from high quality protein sources, and consumption of citrushelp protect from the toxic effects of mercury. Mercury is extremely toxic andcan cause depression and many symptoms associated with depression. Thesesymptoms include,insomnia, nervousness, memory loss, dizziness, anxiety, loss of self-confidence,irritability, drowsiness, weight loss, tremors, paraesthesia (numbness andtingling), hallucinations, headaches, fatigue, muscle weakness, hearingdifficulties, emotional instability, skin inflammation, incoordination andkidney damage. The common areas where mercury is found are: auto exhaustemissions, used motor oils, pesticides, fertilizers, dental amalgams (silverfillings), drinking water (tap and well), leather tanning chemicals, felt,bleached flour, processed foods, fabric softeners, fish (tuna, swordfish,shark, king mackerel and tile fish), calomel (mercury chloride contaminant intalc, body powder), paint pigments and solvents, cinnabar (mercury sulfide -used in red jewelry items), inorganic mercury laxatives, mercurochrome/methiolateanti-infectives, cosmetics (mascara), floor waxes and polishes, woodpreservatives, water plumbing & piping, adhesives, batteries, used airconditioner filters (better here than in the air), broken thermometers, andsome electronic equipment. Consequently, supplementing several grams of thesechelating agents daily is a good idea regardless of current mental health.However, DMSAis the drug, apparently a harmless drug, of choice for removing heavy metals. Succeed! Depression is not a psychosis! Collected Thoughts on Dosage Now, more than 3 years after my very rapid recovery, I still ponder the correctdosage for magnesium, perhaps because this is the number one question asked byreaders. What are the facts? There are some in the FDA whobelieve the U.S. RDA of 400 mg for men and 350 for women is too low, and thatmany persons need as much as 900 a day in their diet for a normal life. Canada,who pays for its citizens health care, has a RDA of 600 mg magnesium foradults. Dosagedepends on the ligand, the thing to which the magnesium is attached. In thecase of magnesium taurate, the ligand is "taurate". Absorption islargely a property of contact of the magnesium ion with the lining of thestomach and intestines. If magnesium is lightly bound to the ligand, then the acidityof the stomach can "ionize" the magnesium from its ligand and convertit to magnesium chloride (from the stomach acid hydrochloric acid) and finallyinto a positively charged ionic form for transfer into the blood where it isthen picked up by various other ligands for transport to cells. Stomach acidcan reduce the magnesium compound to the ionic form for metal complexes thathave low tomodest chemical stability, releasing both the magnesium ion and theligand. The following magnesium compounds have sufficiently low stability thatthey offer very high absorption and are well tolerated. Magnesium acetate,chloride, citrate, gluconate, glycinate, lactate, malate, succinate, sulfate,tartrate and taurate are all very good, ionizable sources of magnesium.Intravenously, hospitals give magnesium sulfate. Magnesium chloride would bebest, but it is very hygroscopic and difficult to properly package, but itmakes a wonderful oily skin lotion when present in more than 25% concentrationsin water and is readily and beneficially absorbed. Onthe other hand, magnesium oxide, magnesium hydroxide, magnesium stearate andmagnesium carbonate are totally useless (and dangerous) because they are tootightly bound together for the stomach acid to dissociate into ionic form andthey will not benefit humans at all. If you rely on them for your dailymagnesium, you will soon die or become so ill that you will change your ways.This medical journal article abstract reported that "taking magnesiumcitrate was best absorbed, and that magnesiumoxide was no better than taking placebo." This medical journalarticle reported that "Resultsindicated relatively poor bioavailability of magnesium oxide (fractionalabsorption 4 per cent) but significantly higher and equivalentbioavailability of magnesium chloride, magnesium lactate and magnesiumaspartate." Another article reported "Theincrement in urinary magnesium following magnesium citrate load (25 mMol) wassignificantly higher than that obtained from magnesium oxide load (during 4hours post-load, 0.22 vs 0.006 mg/mg creatinine, p less than 0.05; duringsecond 2 hours post-load, 0.035 vs 0.008 mg/mg creatinine, p less than 0.05).Thus, magnesium citrate was more soluble and bioavailable than magnesiumoxide." This can be interpreted to mean that magnesium oxideraised blood levels of magnesium only 1 / 37 that of magnesium citrate. NOTE: Ipersonally know someone that took 500 mg of magnesium from magnesium oxideevery day for 40 years and died of a massive heart attack. These dirt cheapinorganic forms of magnesium will not work, except in very much larger doses,which greatly increase risk of diarrhea. In fact magnesium hydroxide is mainlyuseful to treat constipation (Milkof Magnesia). All of the useful, ionizable compounds of magnesium havea metallic, mildly unpleasant taste. On the other hand magnesium carbonate,oxide, stearate and hydroxide have no taste. These compounds are so tightlybound not even the taste buds are affected by them. Always taste-test eachbottle of magnesium to detect improperly labeled products. Improperly labeledmagnesium products do exist in the United States and they do cause many peopleto complain that "magnesium doesnt work". Obviously, neurotoxic-to-usligands (glutamate and aspartate) and oxides, carbonate, stearate andhydroxides must be avoided. If I were writing the laws, they (the oxide,hydroxide, carbonate, stearate, glutamate and aspartate forms) would be illegalfor human and animal consumption. Actually,magnesium stearate has an important function in the manufacture of drugs andnutritional supplements, that being as a "tablet lubricant".Magnesium stearate is totally non reactive with all other chemicals, drugs andnutrients, and it has high lubrication properties. This lack of chemicalreactivity and lubrication property makes it a necessary ingredient forinclusion in nearly all compressed tablets (but not gelatin capsules). Withoutmagnesium stearate as an additive, machinery that make compressed tablets wouldnot function correctly. The parts would stick together. Magnesium stearateprevents tablet-making machinery from sticking, and it allows tablets to bemade by the millions per day without any damage to the equipment. Withoutmagnesium stearate, the equipment could only make a few, perhaps less than 100tablets per day, due to massive equipment failure from lack of lubrication. Muchof this essay relates to and asks why one needs so much supplemental magnesiumto maintain mood? Normally, people dont consider magnesium as a part of theirnutrition, even though magnesium is the second most prevalent mineral insidetheir cells (potassium is first). Have you ever seen magnesium on a foodingredient label? Not likely. I know I havent, except for Planters® nuts.Clearly people with mood disorders leak or do not properly absorb magnesium.Consequently, without supplements of magnesium we are in desperate condition.There is an importantsection in this essay that explores in depth the question of why weleak magnesium and cant properly absorb it. Please read that section to seewhich factors might be involved in your personal situation. You will probablyneed to discuss these factors with your physician. Briefly, there are two mainreasons, kidney (urinary) and gastrointestinal (fecal) losses. Some losses arecaused by damage to these two organs by common drugs, usually prescriptiondrugs like steroids, birth control pills, antifungals, laxatives andantibiotics. Other causes of damage include poor diet, endocrine disorders,parasites, infection and many other shown in this link.In my case, I know medicines damaged my gut by treating a yeast infection firstwith prescription antibiotics (improperly prescribed) and then with steroids (apotentially dangerous medicine). Did that further predispose me to depression?I think so. Thereare four very important dietary causes of low magnesium, which are: (1)"Leaky gut Syndrome" - inadequate intestinal bacteria, (2) insulin /sugar problems and (3) improper calcium / magnesium ratio, and (4) low bileproduction. During our youth, we are usually immune to each of these problems,but as we age (either in years or from toxins such as drugs or abuse of sugarsand calcium), our ability to defend ourselves from these factors declines,sometimes to the point of illness. We will now discuss the main underlingnon-medical reasons for low intracellular magnesium, which cause depression(and many other common illnesses). "LeakyGut Syndrome" Theanswer to the question, "How much should I take to cure mydepression?", closely relates to what caused the magnesium malabsorptionor leakage. In nearly all cases severe stress (metabolic,psychological, environmental, physical) is involved as a predisposingfactor. However, "LeakyGut Syndrome" may be the most frequent cause of our inability toabsorb magnesium. In nearly all cases, improving digestion by any meanspossible, such as use of stomach acidifiers (AC Vinegar), enzymes, CoQ10,soluble fiber, and correcting "Leaky Gut Syndrome" are easy andshould be our highest priorities for rapid recovery. How? First, we mustrealize that insufficient stomach acid prevents absorption of mineralsincluding magnesium, and that anything that irritates or damages our intestinesimpairs our ability to absorb magnesium. If magnesium is not absorbed throughthe walls of the stomach, in the large intestines magnesium ions attract vastnumbers of molecules of water and promote retention of water - the usuallyaccepted cause of its laxative effects. However, inadequate production of bileand the resultant diarrhea may be far more important in our inability to absorbsufficient magnesium. We must also realize that magnesium when present in thegut in sufficient concentration acts on our intestinal flora in the same way asan antibiotic - a definite gut irritant! This action may be because magnesiumions (especially as magnesium chloride - the form of magnesium present in ourbodies as result of hydrochloric stomach acid) have strong, wide-spectrumantibiotic action. The antibiotic action of magnesium ion, using Epsom Salt, is wellappreciated in veterinary medicine, and is used daily in treating topicalwounds in animals, particularly abscesses in hoofs of horses. Also, Walter Lastrecounts its early use in humans as an antibiotic here.Why magnesium ion is not used as a broad spectrum antibiotic in people today isunclear, but probably has little to do with efficacy and much to do witheconomics. Regardless, if sufficient magnesium gets into the large intestines,it can and often does disrupt the normal flora of the gut causing a form of"Leaky Gut Syndrome" in the absence of adequate bile. This effectresults in inadequate absorption of magnesium, calcium and many other nutrientswhich can cause many disorders including depression. Treating "Leaky GutSyndrome" therefore becomes a novel way to treat depression. How is "Leaky Gut Syndrome" treated? First, identify and avoid thingsthat irritate the gut such as foodallergens, alcohol, caffeine, sugar (excesses cause intestinal yeastovergrowth) and drugs. Second, probiotics (life-sustaining bacteria normal andrequired in the intestines) such as acidophilus lactobacillus (available atpharmacies, health food and grocery stores) are needed to maintain and replaceintestinal flora killed by excess magnesium ion. Only the strongest, fresh(refrigerated) available should be used, in a sufficient amount (6+ billionviable microorganisms per dose) and at a frequency (3 to 5 doses a day) toterminate diarrhea nearly overnight. Taking probiotics at times of the daydifferent from magnesium only makes sense. Just like we would never takeantibiotics at the same time of taking probiotics, we must not take magnesiumwith probiotics. There seems to be zero risk of overdosage using qualityproducts, but mixedprobiotic cultures may not be useful particularly if un refrigerated,because they have the habit of killing each other in warm environments whenstored for a long time. If you want to get really serious about GI health, dowhat I do, use refrigerated 450 billion bacteria VSL#3 packets severaltimes a day. Gas may be a side effect until the body adjusts. Ask the storeclerk which probiotics have been shipped and maintained in a refrigerated stateand which are the strongest. Third, psyllium husk fibers or bars without addedsugar are very helpful in providing intestinal bulk and harborage for theintestinal flora. Some researchers say that damage to the gut repairable usingprobiotics takes from 3 to 6 months, even though diarrhea can usually be terminatedwithin a few days. Consequently, we must avoid the temptation of earlywithdrawal from these life- and health-sustaining agents. We need to rememberthat diarrhea is not necessary for there to be "Leaky Gut Syndrome".Diarrhea is only one symptom of this disorder. Learn more about how and whytreating "LeakyGut Syndrome" is vital to general health recovery, Kefir is vital inrepopulating the intestines with friendly fungus after killing Albicans, anovergrowth of which is a potent cause of low magnesium. Theamount of magnesium that we ingest is not as important as the amount we absorb.Many times magnesium tablets do not quickly dissolve in the stomach, resultingin entire tablets getting into the intestines where they always cause diarrhea.Allowing a tablet to dissolve in a glass of water or in the mouth will revealproblems with tablet dissolution rates. In cases of slow dissolution, tabletscan be crushed and dissolved in a small glass of water with soluble fiber. Ihave an indelicate pallet, and I chew the tablets to a powder. I dont know ifothers can do the same. Whatis the result of curing "Leaky Gut Syndrome" in the treatment ofdepression with magnesium? Perhaps most importantly, the total daily amount ofmagnesium required to improve mood is lowered. On occasion, repair is socomplete that supplemental magnesium may be discontinued after a few monthswithout recurrence of depression. Importantly, if we can cure "Leaky GutSyndrome" and our mood improves to normal, we can be assured that we havefixed a serious problem using a very simple and harmless technique that allowsus to rule out more complicated causes for our problems with mood. Who couldsay that treating depression with probiotics is not better than treatingdepression with Prozac®? Taurine- The Perfect-Poop Maker! Inadequateproduction of bile, which is made in the liver and aids in proper digestion offats, probably is five times more responsible for diarrhea and malabsorption ofmagnesium than any other single factor while taking therapeutic doses ofmagnesium. How can we get our bile production high enough to improve ourabsorption of magnesium? Cottage cheese, low in calcium and very high intaurine (1700 mg per cup), is a good food source. Taking taurine supplementsalong with various ionizable magnesium compounds (such as magnesium acetate,chloride, citrate, gluconate, glycinate, lactate, malate, succinate, sulfate,tartrate), or magnesium taurate (1:6 stoichiometric ratio), seems to do the trick,because both often result in perfect poop. Loose stools normally attendant withdaily 1200 mg magnesium dosage (split into 200 to 300 mg doses given 4 timesper day), appeared completely preventable by taking six times the dosage oftaurine with the magnesium doses (for example: for each 100 mg magnesiumdosage, about 600 mg of taurine is ingested). Taurine is a conditionalessential amino acid for humans, well known to be essential in human infants,but not in adults (except in aging, where its absense may be responsible forvast morbidity and early mortality). Its other main function is in preventingcardiac arrhythmias and palpitations, and regulating cardiac rhythm generally,by supporting potassium metabolism too. Since I have had an increasingly severeproblem with cardiac arrhythmias (PACs), such is the reason I experimented withtaurine. Although the arrhythmias were slowly benefited over a one month periodand nearly disappeared, the poop issue became immediately evident the firstmorning after my initial taurine dosage. I searched the Internet and PubMed forand found only that "excess taurine acts as a diuretic and laxative".I disagree for the doses we are taking, but perhaps this is a problem forreally large doses (much higher than our 6 grams per day). Even though I usemagnesium taurate, that is not enough taurine for me. When I also add 2 gramsof taurine with each meal and at bedtime to prevent bothersome cardiacarrhythmias (PACs), I do not notice any laxative effects from taurine. Here isan excellent 1998 article about the therapeutic value of taurine by Timothy C. Birdsall, ND,Executive Editor of Alternative Medicine Reviews. Here is the only scientific articleon treating cardiac arrhythmias with taurine. This is a shame because cardiacproblems nearly always involve low taurine, and tauine will keep you alive inmany very severe cardiac illnesses. Taurineis supposed to be one of the most abundant amino acids in the body. It is foundin human and animal central nervous systems, skeletal muscles and is veryconcentrated in brain, heart and eye tissues. It is synthesized from the aminoacids methodize and cysteine, in conjunction with vitamin B6. Animal protein(particularly seafood) is a good source of taurine, but it is not found invegetable protein. Vegetarians with an unbalanced protein intake, and thereforedeficient in methionine or cysteine will have great difficulty manufacturingtaurine. Dietary intake is thought to be more important in women as the femalehormone estradiol depresses the formation of taurine in the liver. Taurinefunctions in electrically active tissues such as the brain and heart to helpstabilize cell membranes. Taurine seems to inhibit and modulateneurotransmitters (like glycine and GABA) in the brain and helps to stabilizecell membranes. It also has functions in the gallbladder, eyes, and bloodvessels and appears to have some antioxidant and detoxifying activity. Taurineaids the movement of potassium, sodium, calcium, and magnesium in and out ofcells and thus helps generate nerve impulses. Zinc seems to support this effectof taurine. There have been reports on the benefits of taurine supplementationfor epileptics. It has also been found to control motor tics, such asuncontrollable facial twitches. In Japan, taurine therapy is often used in thetreatment of ischemic heart disease. In some people trying both magnesium andtaurine for OCD, taurine seemed more effective, and some are saying thattaurine cured their OCD. Lowtaurine and magnesium levels have been found in patients after heart attacks.Like magnesium, taurine affects cell membrane electrical excitability bynormalizing potassium flow in and out of heart muscle cells. Supplementsdecrease the tendency to develop potentially lethal abnormal heart arrhythmiasafter heart attacks. People with congestive heart failure have also respondedto supplementation with improved cardiac and respiratory function. Taurine isnecessary for the chemical reactions that produce normal vision, anddeficiencies are associated with retinal degeneration. I call taurine my"heart lube". Besidesprotecting the retina, taurine may help prevent and possibly reverseage-related cataracts. Low levels of taurine and other sulphur containing aminoacids are associated with high blood pressure, and taurine supplements havebeen shown to lower blood pressure in some studies. Other possible uses fortaurine supplementation include eye disease (including scleritis and retinaldisease), cirrhosis, depression and male infertility (due to low sperm motility)and hypertension, and as a supplement for newborns and new mothers. It is vitalin maintaining the correct composition of bile and the solubility ofcholesterol. It has been found to have an effect on blood sugar levels similarto insulin. Veryinterestingly, taurineand glycine exist in the presence of a time- and dose-dependent exchangemechanism. After administering glycine to rats, researchers discoveredthat it produced a notable suppression of hepatic taurine content in the liver.Yet, this taurine decrease was not found in other taurine-rich organs such asthe brain, heart or kidney. The mechanism for hepatic concentration of thesetwo amino acids serves to alter liver concentrations of these amino acidswithout adversely affecting the rest of the body. The significance of this isvery high, because as glycine goes up and taurine goes down in the liver, bileproduction is impaired and intestinal absorption of magnesium becomes greatlyimpaired, helping to explain why diarrhea resulting from magnesium taurate isless prevalent. In some people sensitive to this reaction, magnesium glycinatewould be contraindicated, while magnesium taurate would be more helpful. Inmy case, the simple and really very stupid act of brushing my teeth for manyyears with sodium bicarbonate provoked my cardiac arrhythmias (PACs)! Long-termuse of powdered sodium bicarbonate (baking soda) to brush teeth to increase theoral pH thus ridding the mouth of acid (which damages teeth) as instructed bydentists, can cause cardiac arrhythmias if one is low on taurine. The sameproblem occurs from ingesting too much dietary sodium chloride (salt). The mainproblem with brushing teeth with sodium bicarbonate is that the sodium ion isdirectly transported via lymphatic drainage to the heart, thus directlyupsetting the delicate potassium balance which is otherwise benefited bymagnesium. What would be a better oral de-acidifier for dental hygiene? Why notuse magnesium carbonate or magnesium hydroxide mouth washes? My daughter, whostudies neuro-psychology at The University, says that I was messing up the"actionpotential" between potassium and sodium, thus triggeringarrhythmias. How stupid of me! I should have known this! This is such basicinformation that it should be much better known. Dont you suspect that BigPharma drug companies that sell cardiac drugs want us to know not to abusesodium (or potassium)? Ha! Keep us confused and uninformed, and we keep onpaying! Likeall nutrients, taurineenhances or decreases the action of other nutrients. Monosodium glutamate (MSG)is the sodium salt of the amino acid glutamic acid. If glutamic acidsupplementation is given, as is sometimes done with alcoholics, it tends toreduce taurine. MSG itself can also reduce taurine levels. The amino acidsbeta-alanine and beta-hypotaurine, as well as the B-vitamin pantothenic acid,may also interfere with taurines functions. Zinc, on the other hand, enhancestaurines heart lube effects. Zinc deficiency and combined vitamin A and zincdeficiency are associated with an increased excretion of taurine in the urineand with depleted taurine levels in the tissues where it is normally found.Cysteine (found in meat) and vitamin B6 are the most critical nutrients tosupport the manufacture of taurine in the body of human beings or those speciesthat are able to synthesize enough. The beneficial effect of zinc on taurine isprobably why my zinc lozenges whenused at bed-time allow me to sleep with fewer night-time cardiac arrhythmias.Also, ionic zinc has antifungal activity, consequently, there may be severalmeans by which it is helpful. Forme, my taurine levels were so consistently low that to totally prevent PAC (preatrial contractions) cardiac arrhythmias (harmless but nerve racking extrabeats), I required 3 grams of taurine with each meal and at bedtime, and 3 moregrams at 4 a.m. if I was awake at that time. Here is an article,actually the only article ever written on the ability of taurine to regulatethe electrical activity of the heart. Taurine(my heart lube) is an important regulator of cellular ion transport and osmoticbalance, aspects that are pivotal to renalfunction. The kidney not only regulates body taurine status, butemerging information also suggests that body taurine status is of consequencefor renal function. While reduction in endogenous taurine stores can attenuaterenal excretory function, exogenous taurine supplementation iskidney-protective and augments kidney function in several conditions that areassociated with reduction in diuresis and natriuresis. Thus taurine treatment maybe of potential benefit in conditions that are associated with impaired kidneyfunction and the accompanying dysregulation of body fluid and electrolytehomeostasis. I say that anything that improves kidney function is vital to us. Taurinesupplementation is now recommended for the prevention and treatment of diabetes.In order to determine the effects of taurine supplementation or depletion onthe morphological changes of pancreatic beta-cells in streptozotocin-induceddiabetic rats, rats were fed diets supplemented with 1, 2 or 3% taurine or 5%beta-alanine in their drinking water for 7 weeks. After 3 weeks, diabetes wasinduced by streptozotocin injection (50 mg/kg body-weight). Pancreaticmorphology was observed by transmission electron microscopy. The pancreaticbeta-cell of the non-diabetic (CO) group had the many secretory granules, roughendoplasmic reticulum and rod shaped mitochondria. However, the beta-cells ofnon taurine-supplemented diabetic (EO) group were severely damaged, showingdepleted secretory granules. In the 1% taurine-supplemented diabetic group, thebeta-cells were less damaged compared to the EO group and had some apparentlynormal secretory granules, but most of rough endoplasmic reticulum andmitochondria was destroyed. The beta-cell of 2% taurine-supplemented diabeticgroup had swollen rough endoplasmic reticulum, round-shaped mitochondria andsome apparently normal secretory granules. The beta-cell of 3%taurine-supplemented diabetic group was little different from that ofnon-diabetic group. The pancreatic beta-cell of taurine-depleted diabetic groupwas not destroyed but had many small secretory granules which appearedimmature. This was reflected in the blood glucose concentrations of this group.Therefore, taurine may prevent insulin-dependent diabetes by protection of thepancreatic beta-cell and may also preserve normal secretory granules. From theseresults, taurine supplementation may be recommended for prevention andtreatment of diabetes. Beta-alanine worsened diabetes. Magnesium,however, plays an important role in the regulation of insulin secretion byaltering the sensitivity of the beta cells of the Islets of Langerhans toglucose. TheMSGTruth.org site commented thattaurine was the antidote for glutamate poisoning. I questioned Carol Hoernlein,the founder of the MSGTruth.org site about her point of view and she wrote meback writing: > George, The MSG toxicity - taurine deficiency link theory is my own. I developed the theory over ten years ago. At first in my research of glutamate toxicity and its effect on cardiovascular health, most of the neuro scientific data at the time linked glutamate toxicity to its effect on the amino acid cysteine. (Glutamate and cysteine compete for uptake in the body.) I then was given an article about the amino acid taurine by a colleague. That was the link. Taurine deficiency symptoms are the exact same symptoms of MSG reaction. Particularly a racing heart. (Taurine is the amino acid that regulates heart beat.) When I realized that the body manufactures taurine from cysteine, the pieces fell into place. I then tested my theory. The next MSG reaction I had, I took taurine in pill form. The headache went away, the racing heart calmed down, the blood pressure went down, and I was able to sleep. Since that time, I have used it quite often and always keep some handy as an "antidote". It is interesting to note, that now taurine is being used in Japan to treat high blood pressure. It is also being studied to treat diabetes and epilepsy now. These are also two diseases impacted by glutamate. Glutamate triggers the pancreas to produce insulin, but too much insulin can result in insulin resistance, Type II diabetes, and obesity. Also, MSG is well known as an epilepsy trigger. All these facts point to the conclusion that ingested MSG somehow interferes with taurine formation in the body, perhaps by interfering with the uptake of the cysteine needed to make taurine. It is by no means an "official" theory, but we have had many reports of MSG sensitive persons who report relief of some MSG reaction symptoms by ingesting taurine. It is also interesting to note that the body uses Vitamin B6 to make taurine, and that Vitamin B6 deficiency makes MSG reactions worse. I will be adding a page to the web site soon about taurine, as it is a fascinating amino acid. Hope this explains things a bit better. If you more questions, Id be happy to answer them. Carol A. Hoernlein, P.E. Founder MSGTruth.org Carolsand my personal beliefs have major, scientific support. Taurine preventsglutamate excitotoxicity through regulation of calcium and mitochondrial energymetabolism according to scientists writing in the November 1999 issue of Journal of Neuroscience.They clearly and unambiguously point out that the control of intracellularcalcium concentrations is a fundamental process in neuronal survival andfunction. This, prevention of glutamate excitotoxicity, is exactly what we need,and is a powerful reason I switched from magnesium glycinate to magnesiumtaurate. This importance of this point cannot be over emphasized. Additivetaurine also is a potent sleep enhancer. Aspartate,glutamate, and glutamine, among other amino acids, are excitatory. They areantagonistic to the functions of taurine, alanine, GABA and glycine accordingto a contemporary review oftaurine by Richard Smayda, D.O.. Consequently, Carol is correct,taurine does detoxify glutamates. Dr. Smaydas review is of considerableimportance to all of us interested in magnesium and depression. Dr. Smayda pointsout that major depression is marked by alterations in serum levels of theexcitatory amino acids glutamate and aspartate, accompanied by deviations inlevels of taurine, serine, and glycine as well. In patients who did notrespond to treatment with classical SSRI antidepressants (treatment-resistantdepression - like what we are discussing in this page), characteristicallylower serum levels of taurine, aspartate, asparagine, serine and threonine,with a steep increase in glutamine, were noted. Consequently, magnesiumtaurate is the preferred forms of magnesium for treating benefiting"structure or function" of the body or the "well-being"depression. These alterations may become valuable as diagnostic assessments topredict the response to treatment with antidepressants. I remain extremelycautious about glutamates and aspartates due to toxicity thathas been previously discussed. Here is a link to an importantreview of taurine in biological functions and food sources, with cottage cheesebeing low in calcium and high in taurine (1700 mg per cup). Who sells magnesiumtaurate? I like Cardiovascular Researchs Magnesium Taurate product sold here Accordingto Dr. Smayda, taurine is a necessary and integral element for optimal health.Oral supplementation poses no major threat of toxicity, and its presence infoods makes it widely available to people seeking nutrition-oriented ways toimprove their health. The importance of taurine cannot be overstated andits greater therapeutic application awaits only further research. It truly ispart of the team of nutrients that we require for maintaining optimal healthand sustaining life. However, in those individuals who develop stomach ulcerswith aspirin, for instance, large doses of supplemental taurine may becontraindicated. MFMaCarty writes in MedicalHypotheses: "By a variety of mechanisms, magnesium functions bothintracellularly and extracellularly to minimize the cytoplasmic free calciumlevel, [Ca2+]i. This may be the chief reason why correction of magnesiumdeficiency, or induction of hypermagnesemia by parenteral infusion, exertsantihypertensive, anti-atherosclerotic, anti-arrhythmic and antithromboticeffects. Although the amino acid taurine can increase systolic calcium transientsin cardiac cells (and thus has positive inotropic activity), it has otheractions which tend to reduce [Ca2+]i. Indeed, in animal or clinical studies,taurine lowers elevated blood pressure, retards cholesterol-inducedatherogenesis, prevents arrhythmias and stabilizes platelets--effects parallelto those of magnesium. The complex magnesium taurate may thus have considerablepotential as a vascular-protective nutritional supplement, and might also beadministered parenterally, as an alternative to magnesium sulfate, in thetreatment of acute myocardial infarction as well as of pre-eclampsia. Theeffects of magnesium taurate in diabetes deserve particular attention, sinceboth magnesium and taurine may improve insulin sensitivity, and also may lessenrisk for the micro- and macrovascular complications of diabetes." Concerningpre-eclampsia/eclampsia, MF MaCarty writes in MedicalHypotheses: "The use of parenteral magnesium sulfate for themanagement of pre-eclampsia/eclampsia is well established. In striking analogyto the effects of hypermagnesemia, taurine has antivasospastic,antihypertensive, platelet-stabilizing, anticonvulsant and hypoxia-protectiveproperties. Thus parenteral magnesium taurate can reasonably be proposed as asuperior alternative to magnesium sulfate in the treatment of pre-eclampsia;administered orally as a component of prenatal supplementation, magnesium tauratemight well have both preventive and therapeutic value in this syndrome. In thelight of the hypoxia-protective actions of both magnesium and taurine, suchsupplementation might also protect fetuses experiencing temporary perinatalasphyxia, lessening the risk of cerebral palsy." Concerningmigraines, MF MaCarty writes in MedicalHypotheses: "Although the pathogenesis of migraine is still poorlyunderstood, various clinical investigations, as well as consideration of thecharacteristic activities of the wide range of drugs known to reduce migraineincidence, suggest that such phenomena as neuronal hyperexcitation, corticalspreading depression, vasospasm, platelet activation and sympathetichyperactivity often play a part in this syndrome. Increased tissue levels oftaurine, as well as increased extracellular magnesium, could be expected todampen neuronal hyperexcitation, counteract vasospasm, increase tolerance tofocal hypoxia and stabilize platelets; taurine may also lessen sympatheticoutflow. Thus it is reasonable to speculate that supplemental magnesium tauratewill have preventive value in the treatment benefit to the"structure or function" of the body or the "well-being"of migraine. Fish oil, owing to its platelet-stabilizing and antivasospasticactions, may also be useful in this regard, as suggested by a few clinicalreports. Although many drugs have value for migraine prophylaxis, the twonutritional measures suggested here may have particular merit owing to theversatility of their actions, their safety and lack of side-effects and theirlong-term favorable impact on vascular health." Inthe cat, taurine is an essential amino acid, and one of the best laymans pageson taurine on theInternet is dedicated to cats. In that page taurine is again shown toantagonize glutamates, and visa versa. Recently,it has been suggested by Chinese scientist Zhao Xi-heand co-workers that taurine may act as an antihypertensive substance throughcentral and peripheral mechanisms in animal models and in human essentialhypertension. Taurine is high in seafood and not present in plant food. Foodshigh in taurine are eaten by ocean-loving people in countries including Japan,Sicily, Italy and Greece having a low incidence of cardiovascular disease andvery long life spans. > Taurine content of meats, poultry and aquatic products in China (mg/100 g edible portion) > Food Taurine conc. Food Taurine conc. Conch 850 Hairtail fish 56 Inkfish 672 Yellow croaker 88 Blood clam 617 Eel 91 Clam 496 Chicken leg 378 Shellfish 332 Chicken breast 26 Crab 278 Pork 118 Prawn 143 Pig heart 200 Sole 256 Pig kidney 120 Crucial carp 205 Pig liver 42 Silver carp 90 Beef 64 Taurinewas not detected in egg, bean, rice and other plant food. The lowest prevalenceof hypertension was among people that lived in fishing areas and this may berelated to the high taurine content in their diet. Fujita et al. reported thatwhen 6 g taurine/day was given to young adult males with borderlinehypertension for 7 days, their systolic and diastolic blood pressure decreasedsignificantly to levels similar to those of the placebo-treated controls. Thesame effect from taurine was also found by other nutritionists in China. Zhanget al. compared the blood pressure of three populations living in fishing andfarming areas in China and found that the blood pressure of populations in thefishing area was the lowest. Serum and urinary taurine content were negativelyrelated to blood pressure. They also found that sodium excretion was positivelyassociated with taurine excretion. American scientists attribute this amazingresistance to cardiac problems to Omega-3 essential fattyacids, but the argument for taurine is stronger, however there isconsiderable overlap in benefits. More on taurinein foods by H. Pasantes-Morales in "Nutrition Reports International",Oct. 1989: Taurine is converted from methodize and cysteine, and with help fromsulfur, sodium and chloride changes to taurine. The highest concentration oftaurine was found in clams and octopus (41.4 micromoles/g and 31.2micromoles/g), followed by shrimp and fish (12.4 micromoles/g and 9.1micromoles/g). Beef, pork and lamb meat contain taurine in concentrationsranging 3.5-4.0 micromoles/g. Taurine concentration in chicken leg was 6.6micromoles/g and in chicken breast was 1.4 micromoles/g. No taurine was foundeither in hen eggs (yolk or white) or in dairy products or in honey. Taurinewas undetectable to trace amounts in fruits and vegetables to include rice,corn, oatmeal, pumpkin, rye, wheat, barley, sesame seed, coffee and cacao,black beans, chick peas, peanuts, walnuts, almonds, cashews, hazelnuts,pinenuts pistachios. All analysis were carried out in uncooked samples, andcooking greatly reduced taurine content of most foods. Lookingat the low-taurine diseases above, one notes that they are generally diseasesof aging. One may be led to ask if taurine production by the liver andretention by the kidney are impaired in aging. If yes, does supplementation oftaurine make up for the losses? Epplerand Dawson found that a decrease in hepatic taurine biosynthesis maycause, in part, the observed decline in tissue taurine content in aged rats,and that taurine supplementation does restore taurine blood levels. Their studyindicated that a decline in taurine content may exacerbate oxidative stress inaged rats, which can be reversed by dietary taurine supplementation. Dawson andteam has done extensive research in decline in taurine in aging since 1990. Theyshowed that age-related reduction in plasma taurine may have importantconsequences in respect to regulation of blood pressure, cardiovascularfunction, and cardioprotection, as well as possible CNS complications. Significantage-related declines in taurine content were observed in the spleen,kidney, eye, cerebellum and serum. Taurine supplementation corrected thesedeficits in tissue content in aged rats, and in many cases increased taurinecontent above that of adult controls. Urinary excretion of taurine wassignificantly reduced in aged rats indicating an increased need to conservetaurine. Taurine-deficient diets did not further exacerbate the age-relateddecline in tissue taurine content, suggesting biosynthetic adaptations to thelack of dietary taurine. Dietary taurine supplementation blunted age-relateddeclines in serum IGF-1 and increases in serum creatinine and blood urinarynitrogen (BUN). Their studies suggest that advanced aging results in ataurine-deficient state that can be corrected by dietary supplementation. Theyalso pointed out that taurine in the brain declined with aging, which wascorrelated with loss of dopamine. I add that such also appears true in humans. Tomy way of reasoning, if taurine production falls off in aging, and if taurineis necessary for kidney preservation of electrolytes such as magnesium andpotassium, low taurine seems to result in greatly reduced health partly by lossof magnesium through the kidneys. Look at this figure which shows the mainbiochemical pathways in the manufacturer of taurine in the body. Click on thefigure to bring up an enlarged version. All of these steps and many nutrientsare involved in the manufacture of taurine (lower right corner of figure).Clearly, if anything goes wrong in this process, taurine is not made and illhealth ensues. LifeExtension Foundation magazine has a presentation of 99 scientific "taurine"abstracts. CoenzymeQ10 (CoQ10) has been reported by some people to minimize the loose bowelsnormally found using large amounts of magnesium. Very little informationconcerning this effect has been found in the literature, but the effect tothose that have tried 100 mg CoQ10 with each dose of magnesium has beenremarkable. Here is a link to "Altered Immunity &The Leaky Gut Syndrome" by Dr. Zoltan P. Rona MD, MSc, that goesinto the biochemistry of leaky gut syndrome and what can be done about itbetter than any other article that I have found. CoQ10 is mentioned here, butlittle emphasis is placed on it. Looking into the relationship between yeastsand CoQ10, one finds that ubiquinones (in the human it is CoQ10) are essentialfor oxidative phosphorylation in both yeasts and humans. The human coenzyme Q,CoQ10, is also administered orally for the treatment of heart disease and otherdisorders. Some patients, however, require much higher doses than others toattain a therapeutic CoQ10 blood level. C.A. Krone et al. proposes that one possible explanation for thisvariability is excessive Candida colonization of the human GI tract. Manycommon medical treatments including antibiotics and anti-hyperchlorhydricagents increase the risk of GI tract Candida colonization. Subsequent uptakeand utilization of supplemental CoQ10 by excessive yeast could diminishavailability for the human subject. Data from one patient and an in vitro pilotstudy using two pathogenic strains of C. albicans supported Krones hypothesis.If C. albicans in the GI tract can hinder availability and interfere withtherapeutic effects of CoQ10, it could be of clinical significance for largenumbers of depressed people having loose bowels from magnesium. Consequently,one can see a cause and effect relationship between ingestion of large amountsof CoQ10 and relief from loose bowels and diarrhea, thus improved recovery fromdepression due to improved absorption of magnesium. Consequently, the yeastsget fed their CoQ10 before we do, and sometimes we starve! Anti-CandidaAlbicans Agents - Ways to Increase Magnesium Absorption Further in this page,I have identified a large number of health conditions that prevent or reducethe absorption of magnesium from the diet. One of the most frequent, I amconvinced, is overgrowth of Candida Albicans in the digestive tract,intestines. Therefore, in the following few sections I cover various antifungalagents, more or less in the order that I uncovered them. Although each isimportant and may be needed for specific reasons, I saved the best (SpanishBlack Radish) until last. These are the anti-Candida Albicans agents that arediscussed in the following sections. You will notice that I did not discuss theOTC and prescriptions antifungals, simply due to my general adversion to drugsgenerally. If you want to learn about them, see your physician, but none ofthem work longer than a week before the Candida morphs to a resistant strain,just like for coconut oil and garlic. Coconut oil Helpful and safe, but works only for a week. Garlic Helpful and safe, but works only for a week. Iodine Very helpful but not safe - thyroid issues Kefir Helpful and safe, but works only for a week, but should be taken every day as our main source of calcium. Spanish Black Radish Helpful and extremely safe, and is my main anti-fungal and anti-cancer agent. CoconutOil: Cure For Everything? Anothernatural anti-yeast treatment is plain old ordinary coconut oil. This naturalsubstance has been known for many centuries to prevent yeast infections in womenin Pacific islands. Finally, the oils in coconut oil have been tested againstCandida yeast. Both capric and lauric acid found in coconut oil in very largeamounts, were totally, absolutely, completely lethal to Candida yeast. Bergssonand Thormar writing in Antimicrobial Agents and Chemotherapywrote: "The susceptibility of Candida albicans to several fatty acids andtheir 1-monoglycerides was tested with a short inactivation time, andultra-thin sections were studied by transmission electron microscopy aftertreatment with capric acid (found in coconut oil). The results show that capricacid, a 10-carbon saturated fatty acid, causes the fastest and most effectivekilling of all three strains of C. albicans tested, leaving the cytoplasmdisorganized and shrunken because of a disrupted or disintegrated plasmamembrane. Lauric acid (also found in coconut oil), a 12-carbon saturated fattyacid, was the most active at lower concentrations and after a longer incubationtime. Read the full article hereand the 1.03 mb PDF version here.It is interesting that people who eat a lot of coconutslive in areas where yeast and fungi are extremely plentiful, yet they arerarely troubled by infections. Only in more temperate climates where processedvegetable oils are the main source of dietary fat are yeast infections, skinfungus, acne, and other skin infections big problems. Much more research needsto be done on the effectiveness of coconut oil in curing Candida, but for nowthe evidence suggests a good quality Virgin Coconut Oil is one of the bestweapons in killing Candida. Muchinformation is on the internet concerning the use of coconut oil totreat yeast infections. It is also an excellent topical anti-yeast agent fortreating vaginal yeast infections. Read why coconut oil is one of the mosthealth promoting foods on Earth here.Bruce Fife reporting in his book: "The overall health of both groups ofPacific Islanders was extremely good compared to Western standards. There wereno signs of kidney disease or hypothyroidism that might influence fat levels.There was no hypercholesterolemia (high blood cholesterol). All inhabitantswere lean and healthy despite a very high saturated-fat diet from coconut oil.In fact, the populations as a whole had ideal weight-to-height ratios ascompared to the Body Mass Index figures used by nutritionists. Digestiveproblems are rare. Constipation is uncommon. They average two or more bowelmovements a day. Atherosclerosis, heart disease, colitis, colon cancer,hemorrhoids, ulcers, diverticulosis, and appendicitis are conditions with whichthey are generally unfamiliar." Enough said? Try 3 to 4 tablespoons perday. It will not make you fat, and best of all it is non-toxic, very muchunlike many prescriptionantifungals. But, start out with a low dose until you find out whatyour side effects from the break down of yeast affects you. You may say,"Yuck, coconut oil is a saturated fat!" Yes, but it is one veryhealthy food, and this is another highly important food that we have beenconned into believing is bad for us by the American SoybeanAssociation, Center forScience in the Public Interest and others interested in promoting theirown products without regard for our health (a trade war). Search for moreinformation about this issue here.Read how coconut oil is the healthiest oilon Earth. Iscoconut oil the cure for many heart problems? YES! Why? Well, the biochemistryis interesting and fairly simple. Candida yeast breakdown products include acetaldehyde.Acetaldehyde, (also a break down product of alcohol, and is found in ripefruit, cigarette smoke and coffee) has been found to concentrate in the heartwhere it adversely affects heart cells, and has significant effects on cardiaccontractility and function. Acetaldehyde can cause fibrosis and enlargement ofindividual heart cells. Also, Candidiasis (yeast overgrowth in the colon andmucous membranes) is well known to cause magnesium malabsorption, thus causingdepression, heart trouble and colon cancer. Put these observations together,and presto, coconut oil looks like it is a cure for depression, cardiacarrhythmias, myocarditis, endocarditis and lone atrialfibrillations (LAF). I suspect all the other problems mentioned abovenot found in the Pacific Islanders are also largely preventable by daily use ofcoconut oil and not drinking alcohol, coffee, smoking, or eating ripe fruit.How many psychiatrists and cardiologists want you to know this? I suspect thereare a few. However, as I previously mentioned, a low to zero carbohydrate dietis also required and the combination does produce temporary side effects.Systemic yeast die-off is so intense by orally taking a tablespoon of coconutoil morning and night, that most people have adverse reactions (Herxheimereffect) to the die-off products, worsening symptoms for a few days to aweek. I liken this paradox being stranded in a boat seeing land, but findingone first must pass through the dangerous breakers, just off the coast. Seewhat Dr. Mercola has to say about the fungal etiology of inflammatory boweldisease here.Clearly, anything that causes bowel problems will impair magnesium absorption. Doyou have a yeastinfection? Do you have: athletesfoot? jockitch, thrush,recurrentcystitis or other vaginal infections, endometriosis,fungalinfections of the nails or skin, problemsfrom exposure to chemical fumes, perfumes, tobacco smoke etc., foodallergies, abdominalbloating, diarrhoea or constipation, pre-menstrualsyndrome. depression,fatigue,lethargy,poormemory, foodcravings, muscularaches, tingling,numbness,burning,unaccountableaches, swellingin joints, erraticvision, spotsbefore the eyes, floaters?, tachycardia,impotenceor lack of sexual desire, symptomsusually worse on damp days, persistentdrowsiness / tired all the time, lackof co-ordination, headaches/ migraines, Moodswings, lossof balance, rashes,mucusin stools, belchingand /or flatulence, badbreath, drymouth or throat, nasalitch and/or congestion, nervousirritability, prostatitis,tightnessin chest, earsensitivity or fluid in ears, heartburnand indigestion, cardiacarrhythmias, HIV/AIDS.I ask again, do you have a yeast problem? I have read that over eighty percentof us do, primarily because we have taken antibiotics and consume a highcarbohydrate and sugar diet. Find out using this questionnaire from the Yeast Connectionsite. Learn more about the benefits of coconut oil and why it is good for you here. Is it possible that the majority of diseases that we think of as beingmagnesium deficiency diseases are really manifestations of Candidasuprainfections? If yes, could antifungals be the preventative or cure for avery large number of divergent chronic diseases? I think so. Walter Last alsoseems to think so in his new on-line book, 66 Natural Ways to CureDiseases. See his section on Candida yeastas the cause of many widely different diseases and conditions including lack ofenergy, digestive disturbances, arthritic joint pains, skin diseases, menstrualproblems, emotional instability, cancer and depression, including suicidaldepression. Killing the Candida yeast is not enough, one must also replace theintestinal microflora as discussed here. I thinkthat principal biological pathways in which Candida causes many diseases isthrough impaired magnesium metabolism and by diets that promote Candida yeast overgrowth.More on the fungusamongus problem at the FungusFocusweb site. Look at the prostatitispage and you will notice that fungus-induced illness (prostatitis) hasmany symptoms identical to magnesium deficiency. In fact, the symptoms ofCandida yeast overgrowth are essentially the same as magnesium deficiency.Candida allergy strongly depresses the bodys ability to absorb magnesium,probably by inducing a leaky gut. Dr. Leo Gallandobserved this in 1985, although his emphasis was on latent tetany with normalserum calcium (low intracellular magnesium). Onthe other hand, go to your physician and ask him if you have a Candidainfection and unless you have a mushroom growing out of your nose, he/she isvery likely to tell you that yeast infections nearly always occur inimmunosuppressant people, and they do not occur in you. Ask him if you might bemagnesium deficient, and he will likely tell you that no one is magnesiumdeficient except for drunks. Why the adverse opinions? Well, if your doctorprescribed magnesium or coconut oil every time you visited, why go? I thinkthat it makes vastly more financial sense to dissuade us from looking for rootcauses of illnesses than to treat simple underlying problems with naturalproducts. Does the idea that "Candida infection" is bogus havesupport on the Internet? Yes, some. There are a fewsites that proclaim "Candidiasis hypersensitivity" to bebogus, but the main antagonist seems to be the QuackWatch site. The QuackWatchsite is pretty clear that systemic yeast infection is bogus. Is it? I dontknow, but if you find benefit from large doses of coconut oil in treating thebewildering variety of Candida-related illnesses, I imagine that you willsuspect that the QuackWatch guy, Stephen Barrett, M.D., needs watching! I doknow this much. Five years ago, I complained of a severe yeast infection, andafter seeing many physicians, and after being treated with many antifungals andantibiotics in the intervening years, I continued to have the problem until Iused coconut oil. Steven Barrett is entitled to his opinion, but this is freecountry and we can disagree in good faith. Who is Steven Barrett? He isreported to be a non-practicing psychiatrist in Allentown, Pennsylvania,working out of his basement, who is laughed at in thispage. Why wouldnt he be practicing? Did he get busted by the state,like my previous psychiatrist (who is now taking magnesium) forself-prescribing psychiatric drugs? What does George think about the disease causing potential of Candida yeast? Ithink Barrett is correct. Candida can not reach all these places to cause theseother diseases, but its breakdown product, acetaldehyde, can and does.Acetaldehyde is an irritant,a toxin,a reproductivetoxin, a mutagenand a carcinogen.It is a dangerous industrialchemical. It is also flammable,and five times more dangerous than the well known embalming fluid formaldehyde,of which it is a chemical relative. How do people detoxify this harmfulchemical? Molybdenumis said to be vital in detoxifying acetaldehyde. In The Candida/Aldehyde detoxpathway and the Molybdenum Connection, about 300 micrograms of thedietary supplement molybdenum, along with the B-vitamin pantethine(the active part of pantothenic acid), taken three times a day has beenrecommended to help people detoxify this truly harmful chemical. Alternatively,molybdenumis found in foods, with potatoes having about 600 micrograms per 100grams. If potatoes are no longer eaten due to their high glycemic index, onemight need a supplemental source for this vital nutrient. On the other hand,the LinusPauling Institute reports that no healthy person has ever been reportedto be deficient of this nutrient, although excesses are toxic . How about HIV/AIDS? Candida yeast is found in nearly all of these patients.Would coconut oil and garlic help treat HIV/AIDS? Dr Mercolathinks so because these oils are also antiviral to a number of virusesincluding HIV, measles, herpes simplex (HSV-1), vesicular stomatitis virus,visna virus and cytomegalovirus (CMV). Dr. Mercola points out that lauric acidis a medium chain fatty acid, which has the additional beneficial function ofbeing formed into monolaurin in the human or animal body. Monolaurin is theantiviral, antibacterial, and antiprotozoal monoglyceride used by the human oranimal to destroy lipid-coated viruses such as HIV, herpes, cytomegalovirus,influenza, and various pathogenic bacteria, including listeria monocytogenesand helicobacter pylori, and protozoa such as giardia lamblia. Some studies arebeing conducted to see if lowering the yeast load in HIV can prevent thedisease from becoming AIDS, with some success. Some studies have also shownsome antimicrobial effects of the free lauric acid. Do you feel like we havebeen deprived of the truth for long enough? Do you think implementation of Codex willprohibit the sale of coconut oil too? Seems like it should if the main purposeof Codex is to protect pharmaceutical company income. Wantto know what that white stuff in your mouth is? Could it be candida? Dentistsoften find candida yeast infections in peoples mouths. Here is a slideshow about oral candida, which is likely to present more than you wantto know. When your dentist chides you about not taking care of your gums bybrushing better, he should be recommending antifungal treatments. Warning!Too much magnesium has been known to cause diarrhea for at least 100 years.Each magnesium ion will attract about 800 molecules of water, which is usuallybelieved to be the cause of the diarrhea. However, toomuch magnesium exponentially stimulates the growth of Candida yeast cellsin vitro, which was preventable by added calcium. Consequently, large doses ofmagnesium without calcium may stimulate intestinal Candida overgrowth in thehuman. Consequently, magnesium should be taken using several antifungal agents,and especially garlicwith coconut oil.These antifungals will also amplify the absorption of magnesium and greatlyaccelerate recovery but may increase toxicity of magnesium due toincreased absorption. Consequently, when magnesium (without calcium) andantifungals are being used therapeutically, potential foroverdose should be considered. Garlic:The Cure for Everything Else! Themedical literature shows that garlic has important anticancer, antibacterial,antiviral and antifungal effects. I am experimenting in the spring andsummer of 2004 with a heaping teaspoon of bottled, commercially prepared mincedor ground garlic 4 times a day to add a second potent antifungal agent to myprogram to kill intestinal Candida yeast and other nasty critters in myintestinal tract. Freshgarlic extract has a greater efficacy than garlic powder extract. Theantifungal effect of garlic lastsabout one hour in the blood, but does not appear in urine. No physicianis willing to tell me that I have a Candida yeast infection in my intestines,even though every time they prescribe an antifungal, I clearly feel better. Youwant to make a physician laugh? Tell him that garlic makes you feel better!They tend to hold their nose and giggle like crazy! So what! So far, garlic ishelping quite a bit. It rapidly allowed me to reduce my magnesium intake by75%, with no evidence of recurrence of any magnesium deficiency symptom.Currently, I only require 250 mg of magnesium supplements per day. My solid,100 percent, totally convinced, no-questions-asked gut-feeling is that garlicin these large amounts contributed more to my feeling of true health and wellbeing than anything else that I have ever tried outside of magnesium taurate.Why? Because it really does the things claimed for it in terms of cleaning outthe intestinal tract, improving digestion and allowing nutrients, andespecially magnesium, to be properly absorbed. Ithank my easily irritated friend Denise from Glendale, Arizona for herpersistence on garlic. Even if she did get irritated at me for not wanting totry garlic, I thank her repeatedly and with great humility. Denise fussed at merelentlessly to get me to try garlic. I had never before in my life eatengarlic, except as an accidental ingredient in some restaurant foods. Havegarlic in the house? You gotta be nuts! Not us! Bad breath! Think about theconsequences of having bad breath from eating garlic and compare the outcomewith the absence of health from having an ineffective, fungally-infecteddigestive tract. The need-more-taurine-for-digestion issue pales in comparisonto the need for garlic. There should be an RDA for garlic. If I had to set oneit would be 12 to 16 cloves per day as commercially prepared minced or groundgarlic, but then again some people react to garlic poorly. In fact, when Itried to eat a clove of fresh raw garlic (fresh enough that it could have growna new garlic plant if I had planted it in soil), I was met with the mostamazing mouth pain. Fresh, raw garlic will cause mouth pain akin to eating avery hot chili pepper. Eating fresh or raw garlic is fine only if it isminced and added to food. I could not chew on a fresh garlic clove like one couldchew on a fresh onion or a fresh carrot, but could if I minced the same cloveand immediately added it to food. In the later case, I could not taste garlicat all. Eating fresh garlic hurts! What about odor-free garlic? No. As far as Ican tell most (if not all) commercial processes damage the ability of garlic toprovide us with the effects we need. All those widely advertised brands, Kwai, Kyolic,Garlinase, Garlique, and others, simply dont provide much benefit.This is because garlic pills are missing the key ingredient (allicin) onlyfound in fresh-crushed garlic cloves. It is possible to extract allicin, butsuch products have not yet been commercialized. Regardless, garlic is the subjectof extensive research.It is allicin that kills germs (bacteria - including anthrax -,viruses, fungi, amoeba). Allicin is the primary anti-cancer agent in garlic.Allicin also lowers blood pressure, control blood sugar levels, even controlsweight gain. Each of these physiologic benefits probably occurs by improvingmagnesium absorption. A fresh crushed clove of garlic will provide from 4-12milligrams of allicin. Unfortunately, allicin is also the odorant in garlic. Iused really large amounts of bottled, minced and crushed garlic to getbeneficial effects (probably without any allicin due to manufacturing and aging- which leaves open the exact cause of garlics benefit), but much less freshraw garlic is needed to get the same effect. Now that I have been taking garlicfor a little over a month, my wife does not fuss at me for bad breath, but shewont follow behind me, because I have this little garlic cloud that followsme. Toomuch magnesium has been found to cause diarrhea for at least 100 years. Eachmagnesium ion will attract about 800 molecules of water, which is usuallybelieved to be the cause of the diarrhea. However, toomuch magnesium exponentially stimulates the growth of Candida yeast cells invitro, which was preventable by added calcium. Consequently, very largedoses of magnesium without calcium might stimulate intestinal Candidaovergrowth in the human, but such remains theoretical. Regardless, I think thattherapeutic doses of magnesium should always be taken using several antifungalagents (because they can become resistant to individual antifungals), andespecially garlicwith coconut oil.These antifungals will also amplify the absorption of magnesium and greatlyaccelerate recovery but might increase toxicity of magnesium due to increasedmagnesium absorption. Consequently, when therapeutic doses of magnesium(without calcium) and antifungals are being used therapeutically, potential formagnesium overdose should be considered. Iodine:The Candida Killer! Perhapsthe worlds cheapest, most traditional, and best anti Candida agent is thesimplest. It is iodine. Yes, I am describing the same iodine found in"tincture of iodine" that your mother used to treat your cuts andscratches when you were a child. Because Big Pharma drug companies havere-educated us to believe that the fancy new (expensive) antibiotics are betterand safer than (dirt cheap) iodine, we have lost sight of the one trulymiraculous and completely natural antiviral, antibiotic and antifungal agent.Nothing is likely to beat iodine in this regard. However, Big Pharma marketinghas taught us that we shouldnt tolerate the deep, long lasting stain thatiodine causes when applied to our skin. Yes, iodine will stain your skin, butwhen used properly that stain can be of enormous value to you in your battleagainst Candida. Scientists say that if you apply a several-inch round stain ofiodine to your skin, say to your belly, that if it disappears within 24-hours,you are iodine deficient. Well, I tried that and my iodine stain alwaysdisappeared within 6 to 12 hours, and I am clearly not iodine deficient.Marketing has also taught us that iodine in excess is dangerous, that it canmess up our thyroid. Physicians, especially surgeons, for many years world-widedisinfected multiple square-foot size areas of skin with iodine prior to majorsurgery, sometimes resulting in toxic overdoses of iodine. Excess iodine canalso damage our thyroid function causing either reversible hypothyroidism orreversible hyperthyroidism. However, the benefits of proper use of smallamounts of iodine are so enormous that iodine must never be neglected ordiscarded or disrespected, or we will pay dearly! And we are paying that price. Howdoes one use iodine to battle Candida? If the Candida infection is intestinal,then we must treat the intestines either through the oral route or topically.That iodine is anti Candida is clear from this report.What I found works extremely well for me is to take 3 mg Prolamine Iodinetablets from StandardProcesses with each meal and at bedtime for about 3 weeks, but neverfor longer than that. (Note: look for "Prolamine Iodine" in theirAlphabetical List.) I repeat! Never take 3 mg iodine tablets for longer than 3weeks because that dosage for longer than 3 weeks can interfere with thyroidfunction. I could not find this product when I first started to researchiodine, so I added a few drops of Strong Tincture of Iodine 7% to a full glassof water and that worked well too. Iodine can never be swallowed straight (itis poisonous straight) and it must always be highly diluted. The taste of asingle drop will provide clear evidence of that! From what we have read aboutCandida Albicans becoming resistant to various antifungals after a single weekof treatment, one could hypothesize that such would also be true for iodine.Thus, there would be no need to treat for more than a week. However, in this article,are the words "All Candida Albicans strains tested showed similarsusceptibility to the medicaments tested." This suggests to me thatCandida Albicans is totally responsive to iodine, and that even if mutationsoccur, such is irrelevant to efficacy of iodine. However, in me after 3 weeksof 12 mg of iodine per day, I noticed that my body temperature has fallen a fulldegree, sugesting mild hypothyrodism. Worse, as one might expect from this figureconcerning hypothyrodism and low magnesium, I notice a strange low leveldepression and malaise that just lingers and smolders, not evident to otherpeople, but clearly evident to me. Time to get off of iodine and continue inthe search for a perfect anti-fungal. Recently,I became curious about a strangely colored large toenail. What was that strangecoloring of the nail? It looked just like the sickening toenails on the Lamisiladvertisements. The infected toenail looked different but did not hurt or feeldifferent. Three-quarters of it was detached from the skin but not loose. Theyhave a really sick advertisement on TV for Lamisil,the new toenail antifungal. The graphics at this site looked like my big toe.So, old George here being too curious to be smart and buy Lamisil, I usediodine to treat my toe and it soaked under my toenail and exactly showed thearea no longer stuck to the toe with a dark brown iodine stain. Iodine isenormously antifungal. I repeated the toenail treatment for about a week eachevening. My wife is really grossed out by my toenail and I can effectively wardher off now by taking off my sock and sticking my toe up in the air. She runsaway. Ha Ha! It is so much fun ;-) I have a blackened toe from the iodine, butshe warns me of a "blackened eye" if I am not good! Ha Ha, me? Begood? What about my arrhythmias? They have been greatly reduced since I treatedmy toe with iodine. This tells me that at least some benign cardiac arrhythmiasare caused by fungal infections, or the breakdown products of the fungus.Cardiology simplified. There goes another unnecessary pharmaceutical (Lamisil)down the drain. Howabout using iodine to treat other fungal infections? How about oral thrush? Well,scientists treating AIDS patients in Kenya, disapointed at the lack of efficacyand expense of antifungals (Contrimazole, Amphotericin B and Nyastatin) haveturned to dirt-cheap two percent Povidine Iodine mouth washes (Betadine iodine)with astonishing success. Read the abstract here.All they did was gargle with it. How often is not stated, but it appears thatthey gargled for about 30 seconds whenever they noticed a return of mouth odor.Iodine is clearly their antifungal of choice, easily surpasing the efficacy ofthese expensive "FDA proven" anti-fungals. Here is a goggle.com linkfor "betadinegargle". Nearly all of these products warn "DO NOTSWALLOW". Too much iodine is toxic, so be careful. Here is a googlesearch for "betadine"and "oral thrush". Bite the dust Nyastatin! Obviously,after waiting a few months from stopping anti-candida treatment with iodine,one can return to use of iodine, perhaps as a 3 mg tablet / day as anirregularly-taken food supplement. Please note that the RDA for iodine is 0.150mg/day (150 micrograms/day), although I personally believe that higher doses ofiodine can be very beneficial to some but not all people. No one knows why somepeople can not tolerate large (therapeutic) amounts of iodine, but I believethat it is because they are too magnesium deficient to handle it. I am dailyreminded that the Okinawans who live to be 120 years old eat much kelp, whichis high in iodine (10 to 20 mg iodine per day) and taurine, and they also getvery large amounts of magnesium from their foods. Another effectiveanti-Candida treatment is to apply tincture of iodine to the skin so that itcan be absorbed from the skin and not the intestines in an equivalent dosage. Icalculated each drop of HumcoStrong 7% Tincture of Iodine to release 1 mg of iodine when applied tothe skin using its special applicator. I am amazed at how fast 10 drops ofiodine disappears into my skin (about 6 hours), while it seems to stay forseveral days on other peoples skin. I am not certain that the"24-hour" test is valid. I think that if there were no othertreatment available for Candida infection, iodine would be a fully acceptablechoice, if the thyroid remains unaffected. Since there are other treatmentsthat should be tried first (unless one is truly desperate), and because one canoverdose on iodine, I mention it last. Obviously, if Candida infection istopical, perhaps genital, iodine might be used directly to treat the infection,but some experimenting with strength would be necessary. Bright red groin arearashes are usually Candida Albicans infections, and they should be aggressivelytreated with topical iodine in my opinion. Tincture of iodine is too strong forapplication to genitalia without stinging and possibly burning, and one mustdilute it with water, perhaps in a 1 to 10 or 100 ratio. The only use of iodine(Lugols solution) to treat genital Candida that I found in the literature wasin mares.Be careful! Repeated application may be necessary. A final thought. Have younoticed that use of antibiotics causes Candida suprainfections? Have we madeprogress? Big Pharma thinks so. Check google for "iodine" and"candida". EckerdsDrug stores in the United States carry Povidone iodine as a topicalanti-fungal. Ioniczinc is also antifungal, and dietary supplements of zinc can also be helpful intreating candida infections. According to this article,it works synergistically with iodine. How much zinc? You wont believe mytheories without substantial evidence, consequently I will refer you to mytheoretical article on treating extremely dangerous disorders (smallpox andbrown recluse spider bites) with extremely large amounts of zinc here. OK. Forgetthat, just dont take more zinc than will make you nauseous or more than onemilligram per pound of body weight a day (2.2 mg/kg) for more than a month. Kefir:The Candida Crusher Previously I have discussed agents that "kill" Candida. Is thatsufficient? I say no, it is not. Think of a pleasant green pasture with lots ofhorses, cows, pigs, goats and sheep happily foraging (analogous to the healthyintestinal tract with its myriads of symbiotically living bacteria and fungi).Next, consider the pasture becoming overgrown with weeds. What happens to theselovely critters? They dont do as well, and dependent upon the weed (toxic ornon-toxic) their lives will be impacted, and in some cases prematurelyterminated. Think of Candida Albicans as being a toxic weed. What do you do? Isit sufficient to kill the weeds? Is it sufficient to just kill the CandidaAlbicans? In both cases the answer is no. Why? They both come back later, andmay even come back with a vengeance. Farmers know this all to well. What does agood farmer do? He will first stop fertilizing the weeds. This is exactlyanalogous to stopping the consumption of carbohydrates like sugar, colas,pastries, doughnuts and so forth. The next step for the farmer is to try tokill the weeds, by tilling the soil (the analogy here is surgery) and applyingselective herbicides. Clearly we do not want surgery! There are many antifungalagents and I have previously described them. OK. Is it sufficient to stopfeeding Candida and then kill the remaining Candida with fungicidals? NO! Thereis a third step, and in the case of both the pasture and our intestines, it isto re-seed. The farmer will plant whatever grass or crop seeds he wants, and wemust repopulate our intestines with fungi and bacteria that will prevent theregrowth of Candida Albicans. Only by use of these three steps do we have achance of defeating these aggressors. Also, it is absolutely insufficient tosimply "eat yogurt" for its acidophilus lactobacillus content. Theselittle bacteria just get eaten by any remaining Candida Albicans. Yummy! Whatmust be done to assure victory over Candida Albicans is to use Kefir afterkilling Candida Albicans with antifungals, not while killing them,because the good guys in Kefir can easily be killed by antifungals, defeatingthe purpose of Kefir. I had never heard of Kefir until May of 2004, but after afew weeks of drinking Kefir, I became very willing to offer glowing praise forthis old Turkish "feel good" product. Kefir is rich in gut friendlybacteria and yeasts. The friendly yeasts in Kefir repopulate the intestinaltract, replacing the dangerous Candida Albicans, allowing vastly improveddigestion, and intestinal health. Accordingto Dr. Mercola,"While both Kefir and yogurt are cultured milk products, they containdifferent types of beneficial bacteria. Yogurt contains transientbeneficial bacteria that keep the digestive system clean and provide food forthe friendly bacteria that already are present. Kefir actually colonizes theintestinal tract -- a feat that yogurt cannot match. Additionally,Kefir contains several major strains of friendly bacteria not commonly found inyogurt: Lactobacillus Caucasus, Leuconostoc, Acetobacter species, andStreptococcus species. It also contains beneficial yeasts, such asSaccharomyces kefir and Torula kefir, which dominate, control and eliminatedestructive pathogenic yeasts in the body by penetrating the mucosal liningwhere unhealthy yeast and bacteria reside -- forming a virtual SWAT team thathouse-clean and strengthen the intestines. Consequently, the body also becomesvastly more efficient in resisting pathogens like E. coli and intestinalparasites. Kefirs active yeast and bacteria provide more nutritive value than yogurtby helping digest the foods that you eat and by keeping the colon environmentclean and healthy. The curd size of kefir is smaller than yogurt, so its alsoeasier to digest, making it an ideal food for babies, the elderly, and anyonewith digestive disorders. Kefiris also rich in lactic acid and calcium. Although we must use Kefir to win thewar against Candida Albicans, each 8 oz of the Lifewaybrand kefir milk product that I used, contained 300 mg of calcium,which certainly has the potential for increasing depression and injuring us asdiscussed here.I used about 3 oz with each meal for the first 4 days. I strongly believe thatwe should not consume so much that it will injure us from excessive amounts ofcalcium. I suggest a long-term dosage not to exceed 6 to 9 oz per day, andperhaps even less when Candida overgrowth symptoms can be kept under control.Lifeway Kefir also contains inulin (not misspelled), which greatly increases absorptionof magnesium, and to a lesser extent, calcium. As we advance ourknowledge of Kefir and our skill in using Kefir, we can use Kefir "Starterkits" from Dr. Mercola, and perhaps by making our own Kefirdrinks, we can use milk that is lower in calcium. Forthe Candida sufferer, following these three steps will very likely solve theCandida problem, as surely as victory over the weedy pasture. Without followingthese three steps, no real victory will occur. Forthe person with genital or skin Candida Albicans issues, frequent and regulardaily topical (both internal and external) Kefir application is a vastly moreeffective and safer Candida albicans treatment than any prescription or OTCdrug. Take a teaspoon or two of Kefir to the bathroom with you and ... If you letit sit on the countertop for a day or two, both its viscosity and efficacyincrease. Also,sacchararomycesboulardi has long been used to treat diarrhea in Europe and is nowbecoming common in the United States. It is drawing attention in HIV/AIDS as ameans to stop diarrhea from over use of antibiotics. Sacchararomyces boulardiiis an anti Candida Albicans fungus that will repopulate the intestines andgreatly improve digestion and absorption of magnesium. It can support gutfunction under many adverse conditions, including food allergies, parasites,Crohns disease, Candida, Salmonella, travelers diarrhea, HIV diarrhea andPseudomonas. Clinical studies also demonstrate the protective effect of S.boulardii in intestinal infections, including Clostridium difficile andcholera. The protective effect of S. boulardii involves several types ofactivity in the epithelial tissue of the digestive tract, includinginactivation of bacterial toxins, stimulation of intestinal immune response,and release of polyamines. The best known brands are Jarrowand Allergy Research. They are available at the best health foodstores, but may not be widely available except over the Internet. SpanishBlack Radish Perhapsthe greatest and best kept heatlh secret of all time is Spanish Black Radishand indole-3-carbinol. This is my favorite anticandida agent. That is notexactly true, it is NOT an anti-candida agent like OTC antifungals, prescriptionantifungals, coconut oil or garlic. It does not repopulate the intestinal tractlike Kefir does in its action. Spanish Black Radish has several agents,apparently in large, clinically useful amount, that increase the function ofthe intestinal immune system, thus making us temporarily immune to candidaalbicans. For those of us that are hypersensitive to Candida Albicans,increasing our immunity to Candida is vital, and is the way to go! The onlysource of tableted SpanishBlack Radish that I have found to date is the product by Standard Process Inc.They sell only to health care professionals, but you can visit their web siteto see where you can purchase their products in your area. Black Radish iseffective in intestinal toxemia, especially for detoxifying the bowels. SpanishBlack Radish Tablets by Standard Process are organically grown and dried ontheir own facilities in Wisconsin. However, one can now find indole-3-carbinoltablets which seem even more potent than the radish formulation. I am taking 50mg of indole-3-carbinol with each meal now that I have found it to be availablelocally from various manufacturers. See this googlesearch. Spanishblack radish, Raphanus sativus, subspec. niger, is a variety of the commongarden radish and is a member of the Brassica family and it is related tobroccoli and kale, but seems to have vastly more of the acitive ingredient thanthese common vegetables. Like its cousins, radish has a long history ofculinary use, though the black radish has been used mostly for well being. InIndia where it is known as Mooli, the roots are used to support a healthy liverand the seeds for menstrual cycles. Across Asia the seeds are also used topromote digestion, and in Chinese medicine, where it is known as Lái Fú Zî,where it is said to transform phlegm and cause chi to descend. In Europe, theroots of the plant are traditionally used to support the gallbladder and isrecommended for this purpose in the German reference book, "HerbalMedicine." Studies from Europe show evidence that it supports liverfunction, while others suggest that Spanish black radish may also inhibitplatelet aggregation. A substance found in radish seeds, raphanin, is thoughtto modulate hormone production in the thyroid gland. Like all members of theBrassica family, it contains powerful phytonutrients, indole-3-carbinol andsulforaphene. Spanish Black Radish help protect against free radicals. Phytonutrientanti-oxidant substances like vitamin C are present in cruciferous vegetablessuch as Spanish black radish. These substances stimulate the body and helpprotect it against free radicals - the highly unstable oxygen molecules thatdamage cell matter, including DNA. Stimulate bodys own system for neutralizingharmful substances. Components such as indole-3-carbinoland sulforapheneare found in Spanish black radish. These two substances stimulate two of thebodys most powerful detoxification mechanisms - the cytochrome P450 and thePhase II enzyme systems - the bodys biochemical pathways for converting toxinsinto harmless or easily excretable substances. If you click on these twolinks, you will be taken to over four hundred medical journal articlesespousing the value of these two ingredients in protecting against intestinal,cancer, but nothing on their role as antifungal agents. This makes me ask ifCandida Albicans intestinal overgrowth is a prelude to colon cancer? I dontknow, but there is nothing that I have found that is more effective incontrolling sensitivity to candida albicans than Spanish Black Radish, mostlikely by action of its indole-3-carbinol content. Another similar productappears to be Russian Black Radish, which is said to works in conjunction withthe liver in the bodys natural efforts to detoxify. It is claimed to mobilizeand help detoxify heavy metals. How on earth did I come up with the idea of Spanish Black Radish for candidaalbicans? I didnt. I walked into PeoplesPharmacy on South Lamar in Austin, Texas and complained to thepharmacist/CCN on duty, Laura, and she said in one sentence: "SpanishBlack Radish - 3 tablets, 4 times a day". I looked at her and thought,"Well, if that isnt the dumbest idea...", but I went along with hersince I was "up the creek without a paddle". I took the littleStandard Process Inc. bottle of Spanish Black Radish home, and well the rest ishistory. It worked perfectly from the first day I used it. How did I know thatit "worked"? My most irritating health issue has been benign cardiacarrhythmias called pre atrial contractions (PACs), and they are caused by aweird combination of low taurine and candida albicans. Taurine in very highdoses (3 grams, 4 times a day) would work for a while, but the fungal growthwould max out in a week and wow! A real mess occurs and massive amounts ofiodine was the only way to kill off the Candida. But, when Spanish Black Radishwas also used with moderately high doses of taurine, my arrhythmias were bettercontrolled than by any other agent. I may mention other treatments for mycardiac arrhythmia problem elsewhere in this 136 page report, but nothing worksbetter for me than Spanish Black Radish as of August of 2005, except pureindole-3-carbinol tablets. Are the other antifungals still necessary? I suspectthat they are to some degree, and daily garlic and Kefir remain extremelyimportant. We must greatly reduce our intake of "fuel" for candidaalbicans. Fuel? Yes, the primary role of candida albicans is to help digestcarbohydrates like sugar. If you are interested in cardiac arrhythmias, then my article "Taurine Role inCardiology and Cardiac Arrhythmias" featuring the fabulous 1974medical journal article "Taurine and Electrical Activity of theHeart" by Chazov et. al is the place for you. The Chazov article is theonly article in the medical literature - that I could find - to scientificallydiscuss the role of taurine in controlling and preventing certain cardiacarrhythmias. To my way of thinking, to ignore taurine and taurine deficienciesin cardiology is medical malpractice, and must be stopped. KillerSugars Regardlessof the ability of antifungals to increase digestion and help absorb magnesiumby control of Candida yeast, excessive amounts of carbohydrates, sugar andspecifically dextrose (glucose), interfere with magnesium metabolism to a graveextent, and feed Candida yeast preventing recovery. Abnormally high urinarylosses of magnesium can also be caused by a number of kidney conditionsdiscussed here.Perhaps the easiest and most important to deal with issue is excessive glucose(sugar), which flushes magnesium from cells and into the urine. High glucosesugars also greatly promote Candida yeast infections of the intestines (and thevagina), death of beneficial intestinal bacteria, and malabsorption ofnutrients (such as magnesium). There may be no greater health problem facingthe West than improper magnesium / glucose ratios. We love candy, sugar, sweetdrinks and rich carbohydrate products. They are the same heavily commercializedproducts that make us fat, cause heart attacks, hypertension, strokes,diabetes, impair our immunity and cause many other diseases, all treatable byexpensive medicines and medical specialists to the delight of thepharmaceutical drug pushers and physicians who will not tell you the truth. Wecan now add depression, and mood disorders to the list. High carbohydrateconsumption causes intracellular magnesium deficiency and high intracellularcalcium, the exact intracellular conditions causing depression. Highcarbohydrate consumption (doesnt matter if its starches or sugars includinghigh fructose corn syrup - which is being use to replace sugar to avoid theAtkins flack) results in high insulin levels throughout the day, and interfereswith sleep at night and obviously greatly increases obesity. This report [Barbagallo,Renick 1994] shows that high blood glucose levels cause the flushing ofdifferent minerals from cells, among which is magnesium. Calcium, on the otherhand, is not affected. These effects have also been seen by Delvaet al. in 2002. Delva showed that only the man made dextrose molecule,the D-dextrose caused problems, while the natural form L-Dextrose, did notcause the problem. This is reminiscent of the problem with man-made D-glutamates.Guerrero-Romeroand Rodriguez-Moran reported low serum magnesium in diabetes in 2002. Barbagalloreported altered cellular magnesium responsiveness to hyperglycemia inhypertensive subjects in 2001, finding: For all subjects, ionized magnesiumresponses to hyperglycemia were closely related to basal ionized magnesiumlevels with the higher the ionized magnesium, the greater the response (n=26,r=0.620, Pnormotensive subjects are resistant to the ionic effects of extracellularhyperglycemia on ionized magnesium levels, and (2) cellular ionic responses toglucose depend on the basal ionized magnesium environment. Altogether, thesedata support a role for altered extracellular glucose levels in regulatingcellular magnesium metabolism and also suggest the importance of ionic factorsin determining cellular responsiveness to non hormonal as well as hormonalsignals. These problems may result from inadequateinsulin, and resultant loss of magnesium though kidneys. This papershows that insulin is required inside the kidneys to prevent magnesium wasting.If nearly all of your insulin is being used to handle glucose in your blood,and there is little left over for use by the kidneys, frank magnesium wastingoccurs, followed shortly by depression, anxiety and various states of hyperemotionality discussed here. Consequently, conserving insulin by dietary means(low glucose consumption) can prevent depression. There are many other causesof renal magnesium wasting, mostly drug and disease related. Increasinglevels of magnesium were found to cause a marked depression ofglucose-stimulated insulin secretion at fixed calcium levels, particularly atlevels which bracketed the concentration of ultra filtrable magnesium found innormal rat plasma (1.3 meq/l), i.e., increasing magnesium from 0.6 to 1.2 meq/ldepressed insulin secretion, and increasing magnesium from 1.2 to 2.4 meq/lresulted in a further depression. Glucose lowering of magnesium (but not calcium) poses problems because calciumis the antagonist of magnesium. This means that resultant higher calcium levelswill further lower magnesium levels throughout the body. After eating ahigh-carbohydrate diet for years, magnesium deficiency and high calcium isoften inevitable, perhaps from inadequate insulin. This relationship will notshow up in blood magnesium tests, because 99% of magnesium is stored inside thecells, intracellularly, while much calcium is found external to cells. Only theExatest orred blood cell magnesium (not whole blood or serum) tests will tell you thetruth about your intracellular magnesium / calcium ratios. If intracellularmagnesium is low and calcium is high, there is little doubt that high glucose /high calcium / low magnesium is the main cause of depression. The reducedintracellular magnesium alters the way cells open the door for glucose. Thelow-magnesium and high-calcium ratio causes the insulin-key to not fit incellular-locks. Also, the intracellular magnesium and calcium content of thepancreas cells change. This makes the pancreas overshoot insulin. The next timeyou eat carbohydrates, the same events occur and it gets worse and worse.Eventually the pancreatic cells stop making insulin and frank diabetes results,requiring insulin shots. Consequently, the high incidence of diabetes occurringin depression and vise versa is explained. Further,type-2 diabetes is caused by magnesium deficiency, and can be cured even in thevery elderly with magnesium in dosages like are used to treat depression. Seethis casereport of an 86-year old woman, deeply depressed, cured of her diabetesusing magnesium. See this Google.com search for "magnesium"and "diabetes" for the latest news. A diabetics diet (avoiding foods with a high glycemic index) may berecommended for most people, but the main dietary culprit for those of us withborderline diabetes is simply to eliminate all candy, sugar, wheat breads,potatoes, beans and especially high dextrose content sweet products from ourdiets, getting us back to a diet more suitable to our paleolithic digestivesystem. Very briefly, we really, really need to get back to a paleolithic diet. Here is agoogle.com search for "diet"AND "diabetics". Here are some recommended booksconcerning getting back to natural diets. Here is some on hypoglycemia and magnesiumrelationships. Here are over 200links on google.com, wherein Dr. Mildred Seelig MD (a world-classmagnesium expert) warns of the Western catastrophe of too much sugar and toolittle magnesium. In Mildred S. Seelig, MD, MPH and Andrea Rosanoff, PhDs newbook (TheMagnesium Factor), there is a 3 page list of alternate names for"sugar", requiring careful reading of labels on processed foods. Iprefer to avoid all processed foods, simply because sugar is in nearlyeverything processed by man. Diabetes increases myocardial (heart) calcium 400times normal causing severe problems including many heart attacks throughcalcification of heart tissues. Eating regularly when not hungry can create astate of hyperinsulin secretion. Insulin increases appetite because it signalsthe need to transport sugar from the blood into the cells. The only known"remedy" for hyperinsulin secreters is hardexercise (60 minutes at 65% maximum heart rate capacity at least 4 times weekly).Seems like snacking on comfort foods would be helpful in depression and who ofus can resist a chocolate bar when we feel bad. But snacking, particularly onhigh glycemic index foods like chocolate and other candies will always causeinsulin to elevate, which will lower intracellular magnesium levels and worsendepression. Remember chocolate and candies are not natural foods but areprocessed foods. Onthe other hand, there are some instances wherein a food has a low GI value buta high "insulinindex" value. This applies to dairy foods and to some highlypalatable energy-dense "indulgence foods" such as jelly beans, Marsbars and yogurt. Some foods (such as meat, fish, and eggs) that contain nocarbohydrate, just protein and fat (and essentially have a GI value of zero),still stimulate significant rises in blood insulin. At the present time,scientists dont know how to interpret this type of response (low glycemia,high insulinemia) for long-term health. It may be a good outcome because therise in insulin has contributed to the low level of glycemia. On the otherhand, I think it may be not-so-good, because the increased demand for insulincontributes to beta-cell "exhaustion" and the development of type 2diabetes. Until studies are carried out to answer these types of questions, theglycemic index remains a proven tool for predicting the effects of food onhealth. Perhaps all that is needed to "safety" foods like these isadditive magnesium. Clearly, carbohydrates require much more magnesium fortheir proper utilization than other foods. Hereis a list of common foods by glycemic index thanks to the IntegrativeHealthcare web site. The index implies an equal weight of foods. A muchlarger file (1 MB) of 1200foods is available. This file is taken from the University of Sydney Glycemic Index website, which seems to be the most authoritative source available. > GLYCEMIC INDEXES OF COMMON FOODS Breads & Grains waffle - 76 doughnut - 76 bagel - 72 wheat bread, white - 70 bread, whole wheat - 69 cornmeal - 68 bran muffin - 60 rice, white - 56 rice, instant - 91 rice, brown - 55 bulgur - 48 spaghetti, white - 41 whole wheat - 37 wheat kernels - 41 barley - 25 Cereals Rice Krispies - 82 Grape Nuts Flakes - 80 corn Flakes - 77 Cheerios - 74 shredded wheat - 69 Grape Nuts 67 Life - 66 oatmeal - 61 All Bran - 42 Fruits watermelon - 72 pineapple - 66 raisins - 64 banana - 53 grapes - 52 orange - 43 pear - 36 apple - 36 Starchy Vegetables potatoes, baked - 83 potatoes, instant - 83 potatoes, mashed - 73 sweet potatoes - 54 green peas - 48 Legumes baked beans - 48 chick peas - 33 butter beans - 31 lentils - 29 kidney beans - 27 soy beans - 18 Dairy ice cream - 61 yogurt, sweetened - 33 milk, full fat - 27 milk, skim - 32 Snacks rice cakes - 82 jelly beans - 80 graham crackers - 74 corn chips - 73 life savers - 70 angel food cake - 67 wheat crackers - 67 popcorn - 55 oatmeal cookies - 55 potato chips - 54 chocolate - 49 banana cake - 47 peanuts - 14 Sugars glucose - 100 corn syrup - 100 honey - 73 sucrose - 65 lactose - 46 fructose - 23 Beverages soft drinks - 68 orange juice - 57 apple juice - 41 Foods listed from highest to lowest glycemic index within category. Glycemic index was calculated using glucose as the reference with GI of 100. Modified from Foster-Powell and Brand Miller (1995). Concerningme, I used to get cardiac palpitations (up to one each 10 beats) from certain"high glycemic index" foods. I found that eating chocolate, candy,eggs or potatoes in large amounts started palpations within an hour, andavoiding these foods prevented them or lessened them. Meat, peanuts and fishhad no effect. As an experiment, I used a few "pinches" of magnesiumsulfate crystals (with an equal amount of fructose for flavor) dissolved andheld in the mouth over a half-hour to stop these palpitations very rapidly, butthey continued unabated if not treated with magnesium, probably due to mylong-term habit of using sodium bicarbonate as a mouth wash to decrease oralacidity as I previously mentioned. Palpitations in me seemed to be a sensitiveindicator of my immediate cardiac magnesium status, which, in-turn, seemed tobe highly dependent upon my sodium intake. Magnesium ingested in this mannerprobably is picked up by the lymphatic and venous systems surrounding the oralcavity area and is transported directly to the heart - much like nitroglycerinor sodium bicarbonate when used as a mouth wash. Magnesium supplementation iswell known to terminatepalpitations which are accompanied by mitral valve prolapse. In thissame article, they showed that 54% of patients with emotional symptoms (anxietyand depression) had these symptoms resolve using magnesium. The literature doessupport the concept of imbalances between calcium and magnesium as causal formany episodes of cardiac palpitations and most more serious and deadly heartconditions. In my case, my cardiac magnesium status was adversely affected bymy long-term use of powdered sodium bicarbonate while brushing teeth tode-acidify my mouth in the interest of preventing caries. As soon as I stoppedusing pure baking soda, my cardiac problems stopped. PerhapsMajid Ali, MD in his wonderful article entitled "Lions, Hypoglycemia,Insulin Roller Coasters, Heart Attacks" from his book What Do LionsKnow about Stress says it best in his 5 faces of sugar-insulindysregulation thesis. He writes of his conversation with his God-like-in-wisdomfriend Choura, "Sugar is the primary villain in human metabolism.Excess sugar in food stresses human energy systems in many ways and causes thedysregulation of carbohydrate metabolism. Sugar-insulin dysregulation has fivefaces," says Choura. "What are those faces?" Ali asked. Chourareplies, "First, sugar creates sudden surges in blood glucose levels - acondition called hyperglycemia. Second, sudden hyperglycemia triggers the rapidrelease of large amounts of insulin from the pancreas - a condition calledhyperinsulinemia. Third, the insulin response to high blood sugar overshootsits mark and drives the blood sugar level below the normal range - a state oflow blood sugar called hypoglycemia. The fourth face of glucose-insulindysregulation is the insensitivity of insulin receptors at cell membranes(peripheral insulin resistance). The fifth face of glucose-insulindysregulation is too much adrenaline -a state you may call adrenergichypervigilance. When an insulin surge drives sugar below the desirable range,the adrenal glands kick in and dispense blasts of adrenaline to counter theinsulin. Adrenaline is one of the most -if not the most -potent oxidant in thehuman body. The oxidative fires lit by adrenaline overdrive the heart causingarrhythmias, tighten arteries producing high blood pressure, rev upnerve-muscle conduction sites causing stiff muscles, jitters and sweating. Andthat sugar-insulin-adrenergic dysregulation is what the stress specialists callthe STRESS RESPONSE." I am breathless in the face of thiswisdom-of-the-ages. I cant help but realize, here we are again; right back atthe stress responsethat we know drives down magnesium levels and causes our depression. We nowalso see that sugar drives intracellular levels of magnesium down, whichindependently causes depression - counter to what we intuitively believe. Whatare we to do about our love affair with sweets? Are we doomed to a life withoutsweets to avoid depression, heart attacks and most of the other illnesses thatplague Western society? Manypeople have a sweet tooth, brought on by the opiate-like activity of sweetcarbohydrates. Yes we are talking about addiction. Complete elimination ofsweetness from our diet is not desirable or practical. Fortunately there is avery sweet food, fructose (not high fructose corn syrup), that is extremelylow on the glycemic index. Fructose (GI 20) is a natural sugar, amonosaccharide and the mirror image of glucose. Fructose has exactly the sameamount of energy, 4 kcal/gram as sugar or dextrose but it is up to twice assweet as sugar therefore much less is required for sweetness. Fructose, fruitsugar, is the natural sweetener found in all fruits. Orally ingested fructosetravels to the liver and can be used there without the need for much insulin.Fructose is converted to glucose in the liver and contributes to an increase inblood glucose, rather than being stored as glycogen. Unlike sucrose and glucosewhich cause quick changes to the blood glucose levels and disrupt the metaboliccontrol of a person with diabetes, fructose is absorbed more slowly and causesfewer changes in blood glucose levels. Fructose does not interfere as muchwith the magnesium / glucose ratio, perhaps because only one-half of the amountof fructose produces the same sweetness as sugar. Fructose is available athealth food stores, but its table use may not be totally satisfactory becauseit is hygroscopic, meaning it will become wet from moisture that it picks upfrom the air. Its primary use in foods is in cooking and preparation of sweetdrinks. Alternatively, to satisfy a sweet tooth, and totally avoid aggravatingdepression, use Stevia, theultra safe, herbal, top secret, super-sweetener that the FDA doesnt want youto know about. Avoid potatoes and eggs (the Classic Mexican-Americanbreakfast-taco which causes diabetes in astonishing numbers) with their complexcarbohydrates, which can have a greater impact on insulin than pure sugar.Regardless of your dietary interests, try for a maximum of 30 grams ofcarbohydrates a day. Keep your intake of high glycemic index foods to aminimum. Thereis also reason to be cautious about fructose, a very sweet carbohydrate. Ledochowskiet al. at the Institute of Medical Chemistry and Biochemistry,University of Innsbruck, Austria found in 2000 that elimination of fructose andhigh fructose content fruits from the diet has great benefit in treatingdepression in people that do not metabolize fructose or sorbitol correctly.They found that when fructose is not well absorbed, when it reaches the colonit is broken down by bacteria to short fatty acids, CO2 and hydrogengas resulting in bloating, cramps, osmotic diarrhea and other symptoms ofirritable bowel syndrome. They showed that fructose malabsorption is associatedwith early signs of mental depression and low serum tryptophan concentrations.They found that a fructose-reduced diet could not only improve gastrointestinalcomplaints but also reduced depression scores by 65 percent after 4 weeks ofdiet (P distension (P signs of depression and of abdominal distension was more pronounced in femalesthan in males. They concluded that fructose- and sorbitol-reduced diet insubjects with fructose malabsorption does not only reduce gastrointestinalsymptoms but also improves mood and early signs of depression. Consequently, ifyou have bloating, cramps, diarrhea or other bowel symptoms, you shouldeliminate all fruits from your diet and not use fructose or sorbitol as asweetener. Youknow that alcohol is a carbohydrate. But did you know that alcohol is a verylarge contributor to low magnesium and depression, as well as dehydration,anxiety, osteoporosis, heart problems and diabetes? Study "alcohol"and "magnesium deficiency" on google.Got a hang-over headache? Trymagnesium. Think about it. Back in the early 60s when I was in the oldStrategic Air Command (SAC), when we got drunk and the APs rounded us up andescorted us back to the barracks, they gave us really large doses of vitaminB-6 (which is vital for magnesium metabolism), and we were usually sufficientlysober the next day to pass for being "present for duty". Magnesiumwould have been better. Dr.Ricardo Brown at Wayne State University found that acetaldehyde (theextremely toxic breakdown product of alcohol) reduced calcium entry into heartcells, which reduced inter-cellular exchanges that allow the heart to pump. Theexposure to alcohol also caused cardiomyopathy, a condition in which thechambers of the heart are dilated more than normal. From there, Dr. Brownlooked into whether those who suffered from diabetic cardiomyopathy orhypertension were worse off than those with normal hearts in response toalcohol consumption. Again, using diabetic or hypertensive rats as models, hefound that the ability of the heart to contract in the presence of alcohol waseven more depressed. His findings, published in the EuropeanJournal of Pharmacology for reduced heart damage from acetaldehydetoxicity was to supplement with magnesium, thus helping to restore propercalcium levels. He showed that in rats the cardiac damage from alcohol was muchlower when large amounts of magnesium was added to the diet. Drunks urinate(waste) very large amounts of magnesium. I can hear it now, one drunk says toanother, "Hey, Billy-Bob, pass me the magnesium." The other drunksays, "No way Jose, get your own." Remember that being stupid is a right,but being too stupid is a wrong. Although some alcohol-industry funded researchsuggests that small amounts of alcohol daily are healthful, perhaps byreleasing magnesium from bone storage depots, I will not waste thenon-alcoholics time in discussing this totally preventable health risk (alcoholism) anyfurther. For me, any alcohol is too much. Can you see how Kefir would preventcardiac problems? Wannahear a really good military story? While I was in SAC, I had a 1952 Buick witha bad transmission. One day I found that some stranger was removing the motorfrom my car with a portable hoist. Actually, he was stealing it. I called theCalifornia Highway Patrol and they arrested him and hauled him off to jail. Thefollowing Monday, I was recounting this story to my Captain, when the Mather AFBcommander called. The General was in a blood-red-faced, rip-roaring rage, andhe wanted me and my Captain front-and-center in his office in an hour. Why me?I was just a lowly airman. When we got there, we saluted and stood tall, nothaving the slightest idea of why we were there, and we were a bit scared. TheGeneral accused me of having his top B-52 crew chief locked up on a trumped-upcharge of stealing my motor. Well, George was not going to have anything to dowith that BS, so I explained the facts to him. Wow! He really didnt like itand was fuming mad and shaking from rage (certainly he was having palpitations).He told me that my actions effectively grounded one of his B-52 bombers thatwas needed for his Chrome Dome missions. ChromeDome was an Air force program that used B-52s loaded with hydrogen bombs tocruise off the northern coast of the old Soviet block, an action whichthreatened life on this planet in a program eventually called Mutually AssuredDestruction (MAD). Well, the discussion and debate got really, really heated,but when it was all over the general told me that he would trade my motor forhis B-52! Hummm. Sounded good to me, but I drove a hard bargain and got thegeneral to fix my Buicks transmission too. I am probably the only person onEarth to have ever held a B-52 hostage for a 52 Buick! Thereare a number of minerals such as zinc, vanadium and chromium that are vital tocarbohydrate metabolism. Without adequate intake of these minerals, life is notpossible, and premature death, cancer, cardiovascular disease, and diseases ofaging (including depression and insomnia) occur. Insulin is often called "insulinzinc" because of the essential role played by zinc. A dietaryintake of more than 15 mg zinc per day is required for good health, and intakeof 100 mg per day has been shown to improvecellular immunity in old people and youngerpeople, while 300 mg per day for 6 weeks impairscellular immunity. The best source of supplemental zinc is zincgluconate. GTF chromium is an essential insulin cofactor too. GTF stands forGlucose Tolerance Factor. Although 65% of the public has glucose intolerance,90% of the public is low in chromium, thus our ability to regulate sugar isseen as a chromium deficiency - but there is more because high glucose dietsflush out chromium 3 times faster than low glucose diets. Chromium picolinatehas long been recommended to enhance glucose handling, but "picolinate"is a pancreatic excretory product (sort of like "urate" or urine is akidney excretory product) and is no longer recommended for use in dietarysupplements. A B-vitamin complex of chromium called chromiumnicotinate is found to be three-times more readily absorbed than otherforms of chromium and is now recommended. The National Academy of Sciencesrecommends 50 to 200 mcg of chromium daily, but less than 10% of the publicgets 50 mcg per day from their diet. Supplements of chromium in 200 mcg dailydoses (1 or more daily) are needed by 90% of the public and all people havingproblems with high glycemic index foods. Me? I used 400 mcg chromium with eachmeal and bedtime to support my magnesium taurate dosages. WARNING: This muchchromium as "chromium picolinate (GTF chromium)" would be highlytoxic. Picolinate is the toxic ingredient. This toxicity isparticularly embarrassing to the U.S. Department of Agriculture since theydeveloped it, patented it and continue to support it. Vanadium can mimic therole of insulin in ratsand in humans ,reducing the need for insulin. See this google.com search for"vanadium" and "glucose". Dietarysupplements of vanadium [as vanadyl sulfate 5000 micrograms (equivalentto 975 micrograms vanadium)] several times a day may be very beneficial inlowering the need for insulin, and is a hot topic of current interest amongstresearchers and body builders. I tried experimenting with vanadium and I tooktwo tablets of 975 mcg vanadium with each meal and bedtime. I found that theseminerals appear to greatly stabilize magnesium balance and seemed to preventits urinary loss. What is interesting here is the absence or deficiency ofthese minerals can reduce the effectiveness of insulin on sugars thus leadingto "magnesium wasting disease" which leads to depression.Redistribution of magnesium by insulin shots into cells may cause lowermagnesium serum levels, which should be interpreted as beneficial notdetrimental. Throughoutthis section on "Killer Sugars", I have acted as if we all knew whatour blood sugar was supposed to be. You have been told by your doctor that therange was "65 to 109 mg/dL". LifeExtension magazine editor William Faloon presents a powerful case thatsuch reference numbers are pure garbage. He presents his point with theobservation that the pancreas, the bodys main blood glucose level regulator,stops secreting insulin when glucose levels drop below 83 mg/dL, this datahaving been published in HARRISONS PRINCIPLES OF INTERNAL MEDICINE, ThirteenthEdition, McGraw Hill, 1994, pages 2001 - 2004. Faloons point is that "thepancreas thinks glucose levels should be no higher than 83 mg/dL and certainlynot as high as physicians say to be "normal", which is a referencerange of "what is observed" in our sick population, and not what itwould be in a healthy population. Following the diet I present below for fivemonths lowered my blood sugar level one hour after lunch to 84 mg/dL. In astudy of 2000 men over a 22 year period, the researchshowed that men with fasting blood glucose values over 85 mg/dL had a 40%increased risk of death from cardiovascular disease than those with lower bloodglucose in otherwise healthy men. Getting sugar out of our diets will not onlykeep depression away but will keep us living longer. Succeed! Depression is not a psychosis! Milk &Calcium Toxicity Thethird dietary cause of inadequate intracellular magnesium is competition bycalcium. This is one very obvious cause, particularly to people who have goneoff their ridiculous calcium supplements and dairy products diet and gottenmuch better in just a day or two. To those people that refuse to eliminatecalcium supplementation (perhaps due to previous advice from a physician), Ioffer my condolences and hope that you have a good long-term health careinsurance policy. People ask me if I worry about not getting enough calcium by"over" emphasizing magnesium. People seem to want to supplement theiralready calcium-rich, dairy product laden diets with calcium too, notmagnesium. Some people are actually afraid to stop drinking milk, even thoughthey are toxic from drinking too much of it and supplementing with calcium totheoretically "prevent osteoporosis". Why? Thedairy industry has used "osteoporosis prevention" as a marketing toolfor calcium. However, milk and calcium supplements do not seem to be thecorrect answer. In countries where dairy products are commonly consumed, thereare actually more hip fractures than in other countries. When put to the test,most studies show that dairy products and calcium supplements have littleeffect on osteoporosis. As surprising as that may be, when researchers havemeasured bone loss in postmenopausal women, most have found that calcium intakehas little effect on the bone density of the spine. There is also little or noeffect on bone at the hip, where serious breaks can occur. Some studies havefound a small effect from calcium intake on bone density in the forearm. Theoverall message seems to be that, as long as one is not grossly deficient incalcium, calcium supplements and dairy products do not have much beneficial effect.Science magazine (August 1, 1996) noted: "...the large body ofevidence indicating no relationship between calcium intake and bonedensity." Why not? For one thing, hormones very carefully regulate theamount of calcium in bones. Other studies have shown that increasing magnesiumintake increases bone absorption of calcium. Why? The balance of calcium andmagnesium must be maintained, and since there is plenty of calcium in ourdiets, bone density increases from extra magnesium is an automatic reaction. Onthe other hand, simply increasing calcium intake does not fool these hormonesinto building more bone, any more than delivering an extra load of bricks willconvince a construction crew to build a larger building. Psychiatristshave known for many years that loss of hormonal control of calcium causessevere mental illnesses (dementias) including depression. Apparently, long term,stress with excessive calcium intake and limited magnesium intake can causeloss of hormonal control of calcium. Whathappens to people that go cold-turkey on dairy and calcium supplements? In thespring of 1998, I had a heel bone density test done using the new FDA approved Sahara ultrasoundtest for osteoporosis, which is made by the Hologic Company. The testcost me $20 and was totally painless, as are all ultrasounds. It was conductedby a respected local clinic, so what did I have to loose? My 1998 test resultwas taken when I was 58. I had a new test done in Spring of 2003 and the fallof 2004. These are my test results for 1998 through 2004. My wife said I was(and still am) very hard headed, and these tests confirm her observations.Until I became depressed in 1999, I had been practicing thehigh-calcium-is-good-for-you-concept too. My bone density has fallen a bit, butmy bone density is still 1 standard deviation higher than average. My heel bonedensity remains high, and T-Scores changed from +0.6 to -0.1 over the fiveyears. These T-Scores are indicative of very low risk of bone breakage fromosteoporosis, and the score is that of a young adult (but I am 63 in 2004). Obviouslymy bone density was not damaged by no-more-calcium-than-I-can-obtain fromvegetables. Also, I drink de-ionized (essentially distilled) water without anymineral content, so that is not a source of hidden calcium. My mental health ismuch better with low calcium and I very much believe in very low calcium as ahealthy way of living, but only if there is adequate magnesium. Please contact Hologicand find a local clinic that can do this test for you before you terminatecalcium. Recheck each year. Inthe Spring of 2005, my daughter graduated from The University of Texas atAustin, and our family and friends attended the graduation ceremony. On the wayout of the hall, we became separated. I climbed upon the head of a giantarmadillo statue to look around to see if i could find my family. I found themand, momentarily forgetting that I was 64 years old and might have osteoporosisfrom low calcium consumption, jumped off the 7-foot tall statue. As I floatedlike a lead balloon to the ground, I realized that I was not too bright, andwondered if I would break a hip upon landing. I didnt and I landed running. Calcium toxicity issomething that even the National Dairy Council has a great concern, saying nearthe bottom of their page: "However,overuse of calcium-fortified foods, calcium supplements, or antacids containingcalcium may increase risk of calcium toxicity, characterized by highblood levels of calcium, kidney damage, and calcification of softtissues." High blood levels of calcium are called hypercalcemia,which can cause: nausea, vomiting, alterations of mental status, abdominal orflank (kidney) pain, constipation, lethargy, depression, weakness and vaguemuscle/joint aches, polyuria, headache, coma (severe elevation) and death(particularly in the elderly who are more sensitive to excess calcium). Kidneydamage includes kidneystones. Do you really want to have "calcified soft tissues"?They include calcifiedarteries (hardening of the arteries), calcified heart valves (mitral valve prolapse),and calcifiedtendons. As we age, calcium also accumulates in the soft tissues of thebody. When calcium deposits in dead tissue, it is called dystrophic calcium(like atheroscleroticplaques). When excess calcium becomes deposited in living tissue, it iscalled metastatic calcium (like arteriosclerosis).Heart attacks and death often result from excess accumulations of calcium inthese conditions but do not occur from excess magnesium, which appears highlyprotective. When calcium gets into cells, the cells turn on, whatever"on" is for those cells. In the case of stress-induced depression andrelated mental disorders, the cells are the neuro synaptic cells of the brain discussed in depthhere. When calcium enters a muscle cell, the muscle contracts. Ifexcessive calcium stays there, the muscle stays contracted and results insevere pain. The familiar knots in our upper backs and necks are just suchcalcified muscles that are stuck in the "on" or contracted position.The pathological version of this condition is called fibromyalgiawhere there are many such knotted muscles. The extreme example of this is rigormortis (as in death), in which all the muscles of the body are flooded withcalcium and contract - permanently. As we age, we accumulate more and moredystrophic and metastatic calcium, and become stiffer and stiffer. Thesolution, balance excess calcium with excess magnesium, or simply dont indulgein the Calcium-At-Any-Cost campaign! Feel like you have been lied to? Yes? Youare right. Interestingly, physicians now, (finally) report that low blood calciumcan be caused by under active parathyroid glands, low calcium in the diet,severe burns or infections, pancreatitis, kidney failure, or low bloodmagnesium. Which of these six possible ways to develop low blood calcium ismost likely to be cause of low calcium in the Western diet? Anybody remembermagnesium fortification or magnesium promotions by any company? Any dangerhere? No. How about calcium promotions and advertisements? Arent theyeverywhere? Yes! Given this apparent intent to poison Americans with calcium,why would anyone be concerned at this juncture about overdoing magnesium? Isthis Al Qaedas secret weapon for killing Americans? NO! We invented this oneall by ourselves, probably thanks to the NIHs unbalancedconsensus statement on calcium (a monograph absent balance withmagnesium). Nothing that I am saying should be construed to mean anything morethan we must feed ourselves in a way that keeps our magnesium and calciumbalance correct, or, in many of our cases, reestablish a proper, healthycalcium - magnesium balance, nearly always by reducing calcium overloads andincreasing magnesium. If we dont want to balance our calcium and magnesiumratios using supplemental magnesium and a low calcium diet, we can always allowpsychiatrists to do it with electroconvulsive therapy (ECT). All of these effects are exaggerated in space flight,and pose serious problems of heart attacks during flight and post flight. Inaddition to the previously described ischemic mechanisms which may lead tocalcium overload of the myocardium and the arterial wall, and potentiallyleading to a myocardial infarction, other conditions complicating spaceflights, can precipitate calcium overload with cell necrosis, i.e.catecholamine elevations, insulin resistance and magnesium ion loss anddeficiency. A major effort is in place to maintain magnesium serum levelsduring space flight, because loss ofmagnesium during space flight is found to be a limiting factor on spaceflight duration. The loss of magnesium is much greater in men and current interest in women in space flightis stimulated by their lower losses of magnesium. Candidaalbicans yeast is a serious problem in space flight because itdepletes acidophilus bacteria and would greatly reduce magnesium absorption. Onemight hypothesize that female astronauts are strongly interested in preventingvaginal yeast infections in space flights and that they use antifungals, thusexplaining these differences. Scientists and physicians will want to read this ten-page report titled "Calcium andMagnesium Deposits in Disease", by MildredS. Seelig, MD, MPH of the American College of Nutrition, a world-classexpert on magnesium. This article points out that most abnormal mineraldeposits are calcareous, occurring in areas of tissue damage that can be causedby magnesium deficiency. Topics covered: Mineralization of arteries and heartby calcium excess, magnesium deficiency. Atherogenic and/or calcemic diets. Lowmagnesium and spontaneous myocardial infarction. High vitamin-D and/orphosphate diet intensifies magnesium deficiency. Stress and catecholamines. Mitochondriallesions of ischemic hearts resemble those of magnesium deficiency. Diabetesincreases myocardial calcium (Ca) 400 times normal. Mineralization bycalcium of human arteriosclerotic arteries with aging due to lifelong magnesiumdeficiency. Infantile and juvenile cardiovascular calcification resembleexperimental magnesium deficiency. Cardiovascular calcification in diabetesmellitus and renal failure, kidneys, urolithiasis, effect of magnesium inpreventing. Soft tissue calcification inhibition by magnesium.Chrondrocalcinosis, enlarged joints, pseudogout Ca-PP-dihydrate. Apatiteformation. Inhibit subcutaneous calcification by injection of CaATP withmagnesium. Articular calcification of uremia. Interstitial and periarticularcalcinosis. Myositis ossifacans. Tendons. Fluoride toxicity. Vitamin-Dtoxicity. Placenta calcification. Pancreatic calcification. Ocularcalcification. Cardiovascular damage prevented by magnesium. These and othersimilar conditions, even in absence of magnesium deficiency, may be responsiveto magnesium treatment over a one year period. The "Calcium-At-Any-Cost" campaign currently underway in the Unitedstates appears identical to the "Vitamin D-At-Any-Cost" campaign ofthe early part of the twentieth century. After many years of campaigning for adiet richer in vitamin-D, people began to get far too much with seriousconsequences. Normal exposure to sunlight provides enough vitamin-D to satisfyhealthy bodily processes for most of us (exceptions includingclinical cases of Season Affective disorder (SAD), and possiblydark-skinned people living in low-sunlight conditions). Supplementing withvitamin-D, pills, enriched breakfast foods, milk, and other sources of vitaminD led to an epidemic of calcification of soft tissues, such as the kidney,heart, aorta, muscle, hypercalcemia, decalcification of bone, muscularweakness, joint pains, and various other symptoms, all being symptoms of excesscalcium. The "Vitamin D-At-Any-Cost" campaign was replaced by the"Calcium-At-Any-Cost" campaign, which has failed us too. It is timeto get serious and address the real problem, magnesium deficiency. EDITORIALOPINION: If a health consciousness revolution occurs and magnesium gets theattention currently afforded calcium, great displacement is likely in medicine,because much of modern clinical practice appears built on the foundation offaulty calcium-magnesium balances. For those of us that have consumed too much calcium relative to magnesium,excess calcium has become a neurotoxin. For example, I used to be sosensitive to calcium, that a single 500 mg calcium dietary supplement inducedin me a strong feeling of depression within 1 hour (relievable with 400 mgmagnesium). To me, this is clear evidence that either treatment-resistant orstress-induced depression are not necessarily psychological or psychiatricdisorders (although depression certainly can be). Rather, these forms ofdepression are a disorder of calcium / magnesium balance. In fact, had I notexperienced these effects, I could not have realized or appreciated howdangerous our high calcium diet actually is. I assume you are no different,and I urge you to tune in to your body better, and note your bodys response tocalcium supplements. See if you dont experience worsened depression or otherworsened moods after ingesting a big wad of calcium. Many people, womenusually, e-mailed me saying that magnesium did not terminate their depression.I always respond with a request for them to review their dietary supplementsand dairy intake for calcium. Invariably, they report between 1000 and 2000 mgdaily intake of calcium, as dietary supplements plus dairy, or that they used anon-ionizable, totally useless, criminally ineffective compound of magnesium,such as magnesium carbonate, magnesium oxide, stearate or magnesium hydroxide.People have also used magnesium chelates of undescribed nature, magnesiumaspartate or magnesium glutamate with greatly worsened symptoms. I report backto them that in my opinion their calcium intake is preventing their recoveryand their choice of magnesium compounds is wrong. Those that make the suggestedchanges usually report back to me with really nice words of praise and thanksyou notes for their very speedy recovery. From these results and others, we caninfer that large doses of ionic magnesium in the treatment of depression andother disorders either: (a) restore hormonal control of calcium or (b) rebalance the calcium / magnesium serum ratio. In my opinion, re-balancing thecalcium / magnesium ratio is more likely. Why? The effects of magnesium,although extremely strong, are short-lived; and continued magnesiumsupplementation is usually required to maintain well being. If hormonal controlwere re-established, it seems to me that we would not need continued largedoses of magnesium daily. This is not to say that over a long time, hormonalcontrol may eventually result, particularly if we eliminate sugar and otherhigh glycemic index foods from our diets and supplement with chromiumand possibly vanadium. Viewed under a dark field microscope, these red blood cells taken from a Gulf War medical reportershow many small spikes sticking out from their surfaces. These cell-surfacespikes are produced by severe intracellular magnesium depletion and excesscalcium resulting in echinocytes.I wonder if presence of echinocytes is predictive of who will benefit frommagnesium therapy in treatment of depression and other disorders. I suspectmagnesium treatment eventually eliminates echinocytes, restoring the picture ofnormal red blood cells. From this microphotograph, overdoing calciumsupplements and foods rich in calcium (especially dairy products) and ignoringmagnesium dietary intake appears to result in visible cellular "calciumtoxicity". This photograph is amazing; and should illustrate a new way ofdetermining severe, potentially life-threatening calcium/magnesium imbalance.The presence of spikes would prevent spiked blood cells from flowing smoothly througharteries and veins. It seems to me that spiked red blood cells (echinocytes)passing through the arteries and arterioles of the heart and brain couldtrigger strokes and heart attacks and all precursor symptoms associated withthese disorders. Remember magnesium is used to regulate receptor sites for neurotransmitters,and is active in the hippocampus (the emotional center of the body). Ourchildren may be at great risk because they think they need to remain thin to beaccepted. Those foods that are high in magnesium that would help them cope withthe stresses of growing up (school yard bullies, PMSing teen girls, and teenlife in general) are not on their plates. However, milk and cheese products areon their plates, and calcium/magnesium imbalances may contribute to schoolviolence in manic or manic depressive (bi-polar) students. Without enoughmagnesium, these young people can loose control over their moods, sometimeswith devastating results. Violence ormeanness to others has not been reported in the medical literature to be causedby insufficient magnesium except in some ADHD, mania or manic-depressivepatients. Consequently, I am not worried about ADHD, manic, manic depressive,or depressive patients getting too much magnesium, rather I am concerned thatour calcium / magnesium balance be corrected. My worries about milk are additive to what some scientistsworry about concerning homogenized milk. "Homogenizing cows milktransforms healthy butterfat into microscopic spheres of fat containing xanthineoxidase (XO) which is one of the most powerful digestive enzymes there is.The spheres are small enough to pass intact right through the stomach andintestines walls without first being digested. Thus this extremely powerfulprotein knife, XO, floats throughout the body in the blood and lymph systems.When the XO breaks free from its fat envelope, it attacks the inner wall ofwhatever vessel it is in. This creates a wound. The wound triggers the arrivalof patching plaster to seal off that wound. The patching plaster ischolesterol. Hardening of the arteries, heart disease, chest pain, heart attackis the result." Atherosclerosis,1989;77:251-6. If you really wantthe scoop, and dont mind reading about the "pus" in milk, enjoy this site. Milk gives people gas too.If you are interested in this topic, one of the best books on it is "Milk:The Deadly Poison", by Robert Cohen. Read it and weap. Some depressed people appear to need more calcium because laboratory tests showthat they are in a negative calcium balance. That means they leak not justmagnesium (hypomagnesemia), but calcium too. They may have accelerated boneloss perhaps from post menopausal osteoporosis or other diseases or disorders.They are in a bad predicament. If they increase calcium they often become moredepressed. If they decrease calcium they believe that they risk breakingbones from osteoporosis or osteomalacia. Magnesium deficiency is usuallyassociated with hypocalcemia (low blood calcium), hypophosphatemia (lowphosphate), and/or hypokalemia (low potassium). Hypokalemia or hypocalcemia areimportant clinical complications of hypomagnesemia. When a person isunresponsive to treatment for hypokalemia or hypocalcemia, magnesium may havebeen depleted. What to do? The medical literature clearly supports taking moremagnesium and taking boron supplements or eating foods high in boron to helpprevent the loss of these critical minerals. Hypokalemia can also be treated byswitching from plain table salt (sodium chloride) to Mortons Lite Salt [50/50sodium chloride / potassium chloride - contains iodide (iodine)], or preferablyby switching to Mortons Salt Substitute (nearly pure potassium chloride - doesnot contain iodide, which must be supplemented by other means to avoid cardiacissues identical to those produced by low magnesium / high calcium).Hypocalcemia has been treated with calcium supplements, but in depression andhyper emotionality, the doses needed are much lower and can be easily be obtainedfrom lower calcium content food (non dairy). IfMortons Salt substitute is exclusively used, you must add iodide (iodine) toyour diet to prevent iodine deficiency-induced cardiac problems identical tothose found from a low magnesium / high calcium diet. The Japanese live to be120 years old consuming a lot of kelp, which is rich in iodine, taurine andmagnesium. Iodine is vital to cardiac health, and must not be ignored to live along life. Here is a good discussion of kelp at this link.A chronic iodine deficiency can cause the sametype of heart disease as is caused by deficiencies in magnesium. Iodinecontaining medication (amiodarone)is used to terminate certain deadly arrhythmias, but chronic overdose hascaused thyroid problems. Hypothyroidismis common, particularly in elderly women, and dietary iodine deficiency remainsan important cause. Hypothyroidism can present with nonspecific constitutionaland neuropsychiatric complaints, or with hypercholesterolaemia, hyponatraemia,hyperprolactinaemia, or hyperhomocysteinaemia. Severe untreated hypothyroidismcan lead to heart failure, psychosis, and coma. Further, iodine can improvedigestion, increasing absorption of magnesium. For example, 10mg/day of iodine, the average intake of iodine in the classicalJapanese diet will eliminate the loose bowels found with excessive magnesium,perhaps by its well-known anti-helminic andanti-anaerobic bacteria activity. Sometimes primaryhypothyroidism occurs due to too much iodine from kelp in the Japanesepopulation, but it has been shown to be reversible in more than one-half ofpatients simply by dietary restriction of iodine for one to two months. Onaverage, the Japanese ingest 0.1 to 20 mg of iodine from kelp daily, with anaverage of 10 mg/day, which is vastly more than the amount ingested byAmericans (RDA is 150 micrograms/day). There are some interesting commentsabout peanuts and soybeans being harmful to thyroid function with coconut oilbeing beneficial to thyroid function here. How about CalMax,the heavily TV promoted calcium supplement with magnesium? NOT FOR US! NO! Whynot? First, CalMax is very expensive, and second it has a highly absorbablecompound of calcium (calcium gluconate) and a poorly absorbed magnesiumcompound (magnesium carbonate). Although CalMax is on the right track, theratios of calcium (400 mg per dose) versus magnesium (200 mg) are biologicallymisleading because the calcium is so much better absorbed than magnesium. Iestimate that CalMax is the biologically functional equivalent of 400 mgcalcium and about 75 mg of magnesium. Consequently, to get 1000 mg (forexample) of biologically available magnesium from CalMax daily, one would alsoget over 5000 mg of calcium, which is decidedly unhealthy. How about CoralCalcium? HA! How about Caltrate? HA! You figure these out for yourself! Calciumhas been hyped as an anti-cancer agent recently on TV. However, thesescientists reported in 1986 that large amounts of calcium supplementsare promoters of cancer relative to the clear anti-cancer action of both zincand magnesium supplements. These scientistsreported in 2003 that large supplements of calcium increase the rate ofprostate cancer. This is not to say that normal intake of calcium found infoods causes cancer, rather large amounts of supplemental calcium doesnothing to help prevent it and appears to promote prostate cancer. Cadmium is awell-known cancer causative agent, which is inactivated in the body by both zincand magnesium supplements but not by calcium supplements according to thesescientists. Consequently protection against cancer is afforded by zincand magnesium supplementation, but not large doses of calcium supplements; andvery large intake of calcium supplements should be considered to be promotiveof cancer. In fact, a comprehensivereview of the evidence links the consumption of milk from cows treatedwith bovine growth hormone (IGF-1 or insulin-like growth factor 1) with anincreased risk of breast, prostate and colon cancer. IGF-1 is known tostimulate the growth of both normal and cancerous cells. Can low magnesiumactually cause cancer? Apparently yes; although finding information on thisquestion has been somewhat difficult. In one article published in the Journalof American College of Nutrition, volume 1, number 1, in 1982, ratsdeprived of enough magnesium in their diets soon develop a 20 to 25 percentincidence of an acute, transmissible, non-spontaneous, lethal lymphoma-leukemiaresembling human childhood leukemia. See this article here. I had an Exatestintracellular mineral test done in March of 2003, 3 years afterstarting and very carefully maintaining a low calcium diet (zero calciumsupplements, and nearly zero dairy products). I was concerned that after 3years of extremely low calcium intake that perhaps I had "over doneit". I was very surprised to find that my intracellular calcium wasout-of-range-HIGH. The high intracellular calcium made my intracellularphosphorous/calcium ratio extremely low and my intracellular magnesium/calciumtoo low. I had tried to limit my sodium intake (like our doctors tell us todo), and was amazed to find that both my intracellular potassium and sodiumlevels were also out-of-range-LOW. See my full report from IntraCellularDiagnostics here foroverall results and herefor individual element concentrations and ratios. I strongly urge all to takethis test before starting a magnesium repletion program and monitor progressafter first month of treatment, and again on a regular monthly or bi-monthlybasis. You may be surprised to find very low intracellular magnesium and veryhigh intracellular calcium are seriously affecting your health. To avoidpossible circadianrhythm errors, test at the same time each day, preferably between 9 and10 AM. Why do you think we have been lied to about the extreme importance tosupplement our diets with calcium? Why do you think that billions of peoplethroughout the non-Western world have never supplemented their diets withcalcium and never drink milk and have no osteoporosis? Thisfigure from (TheMagnesium Factor) by Mildred S. Seelig, MD, MPH and Andrea Rosanoff,PhD, shows that in 1977 Western countries having the highest dietary calcium tomagnesium ratios (Finland, United States and Netherlands) had rampant ischemicheart disease. More data here.On the other hand, Japan with a one to one ratio of calcium to magnesium hadabout 1/10 the incidence of ischemic heart disease. Why do we keep pushing theidea that more and more calcium is healthy; when in fact, it is a principalcause, perhaps the main cause, of heart disease and deaths in the UnitedStates? Are there some vested commercial interest at work here? Why doesnt theNational Institute of Health speak to this horrifying issue? Why doesnt theFood and Drug Administration act? Why do doctors, nutritionists and dietitianspush this toxic drug? Are they stupid? If there is any good to come from takingaway our rights to free choice of vitamins, minerals, herbs and amino acidsthrough implementation of the treaty provisions of CODEX, one wouldhope that calcium supplements would be prohibited. Not likely! I suspect thatvested interests will prevail and magnesium supplements will be restricted, butnot harmful calcium, sodium or sugar. Dr. Seelig points out that immediatelyafter this data was released in 1978, Finland took action and people startedconsuming much more magnesium and potassium and much less calcium and sodium,and that now Finland has a ischemic heart disease rate lower than Japan. Didthe U.S. take similar action? Ha! You gotta be kidding! This figure is from Ben Bests Life Extensionweb site, which is really interesting reading. If you have a bit oftime, visit it. Ben has compiled much information such as this figure. If wesuperimpose the 90% data from Dr. Seeligs work concerning incidence of lethalheart attacks ascribed to too much calcium and too little magnesium, we can seethe impact on life by age and sex in this figure. Clearly, men are moreimpacted than women. Alsonote that about 90% of all suicides occur in depressed people. It isclear that low magnesium causes suicidal thoughts, and causes most (about 90%)of the suicides in this country. Concerning cancer, controllinghypercalcemia is a major part of cancer treatment. Oncology nurses areresponsible for the ongoing assessment of hypercalcemia, including reviewinglaboratory findings as well as evaluating patient symptomatology. Abnormalserum creatinine, calcium, electrolytes, magnesium, and phosphate levels andsymptoms such as constipation, lethargy, and weakness may alert clinicians toproblems with this oncologic emergency. Resolution of hypercalcemia is highlysuccessful when appropriately monitored and treated and leads to a betterquality of life and improved patient outcomes. Magnesium deficiency is notexactly carcinogenic, but certain concentrations of magnesium are needed to prevent cancer. Do you think that lowmagnesium could be causing much of our high incidence of cancer? I do. Yet,there is virtually no call for alarm by our health agencies, or ourpoliticians, or our doctors, or our press; and no champions for magnesiumhaving a national voice exist. Notice that the death rate from heart attacks inmen greatly increases after age 40, which is consistent with the age most menlearn what life is really all about, have wife, children about to go tocollege, heavy personal and professional responsibilities, and find themselvesunder more stress than they can handle. Consequently, the impact of lowmagnesium on human life span in the United States is overwhelming, and is amajor drag on our economy. Think we have been misled about the quality of ourfood supply? Thisfigure from page 5 of "The Magnesium Factor"(taken from the American Heart Association) shows clearly that lethal heartattacks were rare in the early part of the 20th century, and that there wassufficient magnesium in the diet to prevent them. As our need for caloriesincreased and our grain refining techniques improved, more and more people atelarger and larger amounts of refined grains (minus their magnesium) and refinedsugar cane (sugar), and heart attacks greatly increased. The United Statespopulation more than tripled from 76 million people in 1900 to 281 millionpeople in 2000 according to page 14 of this census report,yet in the same time, heart attacks increased ~800-fold. Why participate inyour early demise? Boycott all refined wheat products and sugar! Actually,people live longer now and dont die of other things early in live, liketuberculosis. Yet, low magnesium and high calcium contributes strongly to heartattacks. Ihave a bit of skill in mathematics, so I integrated the data in Figure 1.1 tofind the total number of Americans that have died from heart attacks. Thefigure is a staggering 40,000,000 since 1900. That is the same number of peoplethat live in Spain! That is also slightly less than the total killed in World War II. Likecalcium and magnesium, phosphate is essential to every cell in humans, plants,animals - every living thing. It is necessary for many of the biochemicalmolecules and processes that define life itself. Phosphate is a charged group ofatoms, or ion. It is made up of a phosphorus atom and four oxygen atoms (PO4)and carries three negative charges. The phosphate ion combines with variousatoms and molecules within living organisms to form many different compoundsessential to life. Some examples of phosphates role in living matter include:(1) Giving shape to DNA (Deoxyribonucleic Acid), which is a blueprint ofgenetic contained in every living cell. A sugar-phosphate backbone forms thehelical structure of every DNA molecule, playing a vital role in the way livingmatter provides energy for biochemical reactions in cells. The compoundadenosine triphosphate (ATP), which is extremely dependent upon adequatemagnesium for its function) stores energy living matter gets from food (and sunlightin plants) and releases it when it is required for cellular activity. After theenergy, in the form of a high-energy phosphate bond, is released the ATPbecomes a lower-energy adenosine diphosphate (ADP)or a still lower-energyadenosine monophosphate (AMP) molecule. These will be replenished to thehigher-energy ATP (or ADP) state with the addition of phosphate by variousmechanisms in living cells. The forming and strengthening of bones and teeth.We get phosphate from the foods we eat. Theseexamples show the phosphorus content of some foods (mg/100 grams of variousfoods). Milk 93 Lean Beef 204 Potatoes 56 Broccoli 72 Wheat Flour 101 Cheddar Cheese 524 Dowe get too much phosphate? For some people eating too much cheese, yes, theyare getting too much calcium and phosphate, contributing significantly tomagnesium deficiency. High phosphate (phosphoric acid) content sodas (CocaColas and Pepsi Colas, to name a few) probably should be avoided, if for noother reason they are also high in glucose. Am I greatly worried about too muchphosphate in our diets? Not yet, but only if we avoid cheese and its dualphosphate and calcium load. Insummary, we can do much with our diet. We can ingest enormous amounts ofmagnesium (and fight off diarrhea), or we can save money by using lessmagnesium, ingest few or no high carbohydrate foods (especially sugar, cornsyrup, soft drinks, alcoholic beverages, bread, rice, cakes, pancakes, wafflesand potatoes), terminate our fascination with dairy and calcium (along withcheeses excessive phosphate), and supplement with probiotics to regain ourmental health and defeat depression. Also, we will not need those nastyantidepressants! Whats Left To Eat? After readingwhat not to eat (mainly calcium and sugar), you are probably wondering what isleft to eat. The natural food pyramid on the right shows what I eat every day.It is different from the USDA fodder pyramid in that no man-made refinedcarbohydrates are eaten, as per the strictest version of the Atkins diet(without the "eat all you want of meat and fat attitude"). I hardlyever (about once or twice a year - when trapped at someones party) eat refinedwheat products (white flour), breakfast cereals, waffles, pancakes, bread,cake, candy, French fries, pasta, rice or other starchy foods of any kind.These highly refined carbohydrate foods are heavy in the bottom row of the USDA fodder pyramidand are the main cause of obesity and ill health in America. Even though fatshave twice the calories of carbohydrates, fat people have eaten vastly morecarbohydrates than fats, often in an ill advised attempt to prevent or controldepression. The entire bottom row of the antiquated USDA fodder pyramid isessentially "processed (man-made) foods", and many are also high in neurotoxic glutamatesand very low in magnesium, manganese, potassium and vitamins found in the raw grainsfrom which they were made. I avoided them entirely for a few months and lostten pounds per month during the first 5 months. I now feel much better about myweight. Then, my weight stabilized at a very fit 165 pounds for my 5 foot 10inch frame. Now, I have the flat belly of an 18-year-olds! Here is a web site thatshows what the body of a really fit nutrition teacher looks like followingthese guidelines. He interests me when he equates "white flour" withinsecticide. Turns out that white flour is so low in nutrition thatinsects and rodents cannot survive in it. This was the original reason to"refine" wheat into white flour. In the early 1900s, they did nothave a way of storing grain without it becoming infested with insects androdents. We now are living with "depleted wheat" made by refining.How come we can survive on depleted grains when the insects and rodents cannot? Thebenefits of the natural food pyramid include weight loss, high vitamin andmineral content, lower food cost, low insulin requirements, very few heartattacks and absolutely no food craving. Better yet, my blood pressure fell to100/60 and my blood sugar fell to 84 mg/dL. Why no craving? Because thecarbohydrate foods that I no longer eat have an addictive property due toinsulin production. Once a person stops eating them, the cravings disappear.Fish? Absolutely yes! Popcorn? Tacos? Yes! Anytime! Cheese? Not for me, exceptfor cottage cheese, which is low in calcium and wonderfully high in taurine(1700 mg per cup). Meat? Yes, bring it on buddy! Fish? Of course! Salmon? Yes,this is to die for! Fresh beans, tomatoes, pears, apples, dates, raisins,grapefruit, eggs, nuts, peanuts, cashews, vegetables of all kinds (exceptpotatoes), yes! WARNING: An alternate sources of potassium, which is high inpotatoes, is needed if potatoes are eliminated from the diet to avoid serioushealth problems. Foods high in potassium include fresh tomatoes, bananas,beet greens, dates, raisins, grapefruit, soybeans, Lima beans and other foodsshown on this USDAlist of foods (by their potassium content), or on this easy to read table. When youthink "bananas are high in potassium", remember that it would takeabout ten of them a day to give the RDA for potassium. Processed foods likecakes, Twinkies, doughnuts, puddings, Jell-O, beer, chocolate or candy? No.Once my carbohydrate intake dropped, my craving for them disappeared too, and Inow look at them like other people look at globs of fat! Yuck! Vitamins,minerals and balanced sodium and potassium (Mortons Lite-Salt)salt? Yes, of course! One would need be an idiot not to consume an adequatesupply of repair parts for ones mind and body! NOTE:The Center for Nutrition Policy and Promotion of the U.S. USDA has taken noteof the problem of obesity and low magnesium in our diets and is consideringchanges to the "food pyramid". Watch for changes here.There will be emphasis on "whole grains" only, and refined wheatproducts and sugar will likely take a very substantial hit. Weare what we eat, and I am built mainly of protein, not carbohydrate. Why wouldanyone build their body with excess carbohydrates (or fat) to become fat? Sure,we need some carbohydrate for fuel and amino acid production, but an excesswill always be stored as fat. If you want carbohydrates as well as wonderfullybalanced minerals, try cashewnuts. Interestingly, significant avoidance of dangerous trans fattyacids (trans fats) occurs on this diet. These are the man-made fats(shortening, partially hydrogenated vegetable oils and hydrogenated vegetableoils). Eat butter and use olive oil and coconutinstead! They wont hurt you! Remember that the USDAs main role is to promoteagriculture, not necessarily human health. Read Marion Nestles eye-opener bookFood Politics. DidAtkins discover something new? No. Apparently, the high carbohydrate diet wasfirst found to cause obesity in 1863 by William Banting,and a diet very similar to this diet was found effective in weight loss andappetite suppression. Accordingto Carol Hoernlein of the msgtruth.orgsite, we all must be very careful when restricting carbohydrates, because animbalance of certain amino acids is possible with unintended, adverseconsequences. Tyramineis an amino acid that can be deadly to some taking certain medications likeMAOI inhibitors. The blood pressure can raise dangerously high. It is usually amedicine - food interaction when it is deadly. In cases of folks who aresensitive to MSG, tyramine usually just gives them a headache, but it is quiteupsetting. The other problem with tyramine is that amino acids like it andtyrosine compete for uptake into the brain with tryptophane. Foods that werefound to have high (possibly dangerous) concentrations of tyramine includedchicken liver, air-dried sausage, soy sauce, draft beer, aged-cheese, tofu,sauerkraut and others. When you dont eat enough carbohydrates (complex carbsare best) - and eat just protein (a perversion of the Atkins diet), tyrosinewins the battle and gets to the brain first where it acts as an"upper". Tryptophane is the loser in the race, but the brain needstryptophane to make serotonin - the feel good calming stuff the brain needs tokeep us from getting depressed. Too much protein and tyramine and not enoughcarbs = depression and agitation. Also, too much protein depletes magnesium. Thesereasons are probably why famed psychiatristsJudith Wurtman and her husband Richard Wurtman of MIT recommendcarbohydrates for depression, and in particular, PMS related depression.Unfortunately, abuse of this technique causes enormous illness in the U.S. andWestern culture. Please do not accept what I have written above to mean"no carbohydrates"; rather, please accept it as meaning one shouldeat foods that are not refined. Body fat develops because the body does nothave sufficient minerals to burn the carbohydrates. That is why, IMHO, peoplecan best loose weight consuming diets low in refined carbohydrates,supplemented with large amounts of magnesium and other minerals like manganeseand zinc. Tyrosine imbalance is the reason people - who have misinterpretedAtkins to mean "eat all the steaks you want, but cut out allcarbohydrates" - become acutely ill. Afterpreparing the above natural food pyramid, I realized that the bottom levelfoods (vegetables, meats and fruits) were the first foods eaten by primitivehumans millions of years ago, at the time our digestive systems were designed.Only recently (relatively) were dairy products added to the human diet. Evenmore recently people learned how to bake bread, prepare high carbohydratefancy-foods, and separate out fats and oils from foods. Clearly vitamins andmineral supplements are a twentieth century invention. Consequently, this is areasonably "natural" food pyramid. What can be learned here? Warning!Following the dietary and supplement recommendations outlined here will havethe effect of preventing or correcting hyperinsulinemia, which will result inlife extension of between 30 and 50 years, and much better health. Theseeffects may ruin your personal relationship with your physicians and nurses,reduce profits of major drug companies, reduce the profits of processed foodmanufacturers, reduce hospital admissions, reduce employment opportunities inthose industries and otherwise adversely affect our national Economy. Worseyet, you will be purposefully contributing to the failure of Social Security.Prevention of hyperinsulinemia by following these dietary suggestions willconsequently prevent most cases of atherosclerosis, vascular disease, diabetestype 2, impotence, kidney failure, heart failure, liver damage, stroke,obesity, neuropathy, retinopathy, gangrene and other illnesses. Proceed withthese dietary recommendations only if you agree that these "economic"side effects and Social Security health are irrelevant to you and that youaccept the risk of longevity attendant with eating right. Be warned that if youaccept these guidelines you will be out of step with national health carepolicy, that policy being that you should die before you injure SocialSecurity. Read more about these horrific economic side effects and prospectsfor longevity at the HealingMatters site. CHICAGO-- U.S. life expectancy will fall dramatically in coming years because ofobesity, a major shift in a long-running trend toward longer lives. Obesitylikely will shorten the average life span of 77.6 years by at least five years.Thats more than the impact of cancer or heart disease, said lead author JayOlshansky, a longevity researcher at the University of Illinois at Chicago."We think todays younger generation will have shorter and less healthylives than their parents for the first time in modern history unless weintervene," he said. With obesity affecting at least 15 per cent ofAmerican school-age children, "its not pie in the sky," Dr. Olshanskysaid. "The children who are extremely obese are already here." Ifthe projections proved true, they would reverse the mostly steady increase inU.S. life expectancy that has occurred over the past two centuries and wouldhave tremendous social and economic consequences that could even inadvertentlyhelp "save" the national Social Security program, Dr. Olshanskyand colleagues contend. Everyone knowsthat primary hypertension (high blood pressure) and high cholesterol causeheart attacks (myocardial infarctions). Incidentally, "primary"hypertension means "high blood pressure from unknown causes". We havebeen taught that we must use diet and expensive statin drugs to lower our badcholesterol if we dont want a heart attack. We have been taught that we mustget our blood pressure down by diet (reduce our salt and fat intake and toexercise more) and to take a variety of expensive drugs including diuretics(lowers blood volume), beta-blockers (inhibits adrenaline), alpha-blockers(makes heart beat with less force and relaxes blood vessels), ACE -angiotensin-converting enzymes (spares magnesium and potassium, but loosessodium, and relaxes arteries), vasodilators (relaxes arteries), centraladrenergic inhibitors (blocks certain signals from brain), calcium-channel-blockers(relaxes arteries). As hard as we try, improvements to our diets by reducingsalt and cholesterol and fats have not worked. Also, these drugs are marketedalmost exclusively to benefit cardiac risk factors, not extend life. Do theyalso prevent death from these cardiac-risk factors? Magnesiumdeficiency is the real disease I believe, and heart disease is a symptom ofyears and years and years and years of magnesium deficiency. We do know whatcauses "primary" hypertension, and it is often magnesium deficiency.This may seem wrong and certainly different from what we have been told, but itis a fact either well hidden by pharmaceutical drug pushers or just not knownby them - who knows. Yet, scientistssay magnesium deficiency must be corrected to save patients. It isvital to your heart health that you verify this claim by reading TheMagnesium Factor . Briefly stated, all of the above medicines are poorsubstitutes for magnesium, because magnesium naturally does each of these"drug" functions better than the drugs themselves. How muchmagnesium? That is the catch. We must take enough magnesium each and every dayto combat the effects of stress in its action in depleting magnesium, and thisamount is higher than has been historically true. Our "modern" way oflife is very stressful, and we all leak magnesium because of stress, some morethan others. I cant personally see how we can get our blood pressure down to100/60 (like it was when we were teenagers) with less than about 500 to 750 mgof supplemental magnesium per day. Wouldnt that be expensive? NO! Certainlynot compared to the cost of these drugs, and certainly not when compared to thelife-extending properties of magnesium compared with these drugs. Expensive toSocial Security? Maybe. Expensive to Medicare? NO. Your health care expenseswill plummet downward, and you may forget the name of your doctor! Iwas not particularly satisfied with the Figure above by Seelig andRosanoff, because it does not consider changes in population.Therefore, I used the UnitedStates Census data for the decennial years from 1900 to 2000, plustheir 2003population estimate and recent death rate data for 2003 from the Centerfor Disease Control and Prevention as reported by Maureen Rouhi in Chemicaland Engineering News to modify their figure. Notice again that thedeath rate per million Americans is ten times what it was in 1900, before grainrefining got going. I wonder if Al Qaeda had a hand in "refininggrain" to make nutrient depleted foods for us to starve on so slowly andpainfully? Nah! We did this to ourselves! We are just really, really stupid. Astime went on, the deaths from low magnesium/high calcium increased from nearlyzero in 1900 to what they are today. Notice that after 1970 the death rate starteddownward, but the data for 2003 shows progress has recently been lost. I wonderwhy the cardiac drugs are not working as well as before? Drs. Seelig andRosanoff suggest that the statinsare depleting magnesium, and coupled with our increased intake of calcium inthe last 5 to 10 years to "prevent osteoporosis", we see the effectin an great increase in deaths by heart attack. "Modern" science isfailing us, and killing us, all for the want of magnesium. Remember that thegovernment has laws and regulations that prohibit nutrients from being marketedto treat, cure and prevent diseases. The pharmaceutical drug pushers can notpatent magnesium (or other nutrients), so they will not mess with it. Wow! Whata way to run a country! Actually, companies can market nutrients to treat,cure, prevent disease, but only after they have had a New Drug Applicationapproved by the Food and Drug Administration at the cost of a half billiondollars. No company will spend that kind of money on a non-patentablesubstance. Consequently, the impasse remains, and the law stands - until a morereasoned Congress figures out what is going on and puts a stop to the murder.What is likely to happen is that Congress will approve the CODEX treaty andallow the pharmaceutical drug pushers to have a total monopoly on nutrientslike magnesium so that they can mark up the price 10 to 100-fold and billMedicare. I say why do that? All we need is for the government to passrealistic laws that promote the fortification of "depleted flour"with nutrients including magnesium to the amount naturally found in grains,make calcium supplements without an equal amount of magnesium ILLEGAL, and addmagnesium back into drinking water and soft drinks. That would be a muchcheaper means of restoring health to America than to impose a heavy-handedtreaty like CODEX which will mainly benefit the big pharmaceutical drug pushersand not the American people. Takea look at the AmericanHeart Association statistics (6 mb file) here. You will recognize Drs.Seeligs and Rosanoffs figure on page 4. Perhaps the most startling finding inthis data is the reduction in death rate for men in the last 20 years while thedeath rate for women has increased. I say the reason for this difference isbecause women supplement their diets with calcium to ward off osteoporosis, andmen do not. Lookat what Dr. Mildred S. Seelig, MD, and Andrea Rosanoff PhD say about magnesiumand statins in their 2004 article in the Journal of the American College ofNutrition article titled Comparisonof mechanism and functional effects of magnesium and statin pharmaceuticals.. Hereis the abstract: "Since Mg(2+)-ATP is the controlling factor for therate-limiting enzyme in the cholesterol biosynthesis sequence that is targetedby the statin pharmaceutical drugs, comparison of the effects of Mg(2+) onlipoproteins with those of the statin drugs is warranted. Formation ofcholesterol in blood, as well as of cholesterol required in hormone synthesis,and membrane maintenance, is achieved in a series of enzymatic reactions thatconvert HMG-CoA to cholesterol. The rate-limiting reaction of this pathway isthe enzymatic conversion of HMG CoA to mevalonate via HMG CoA. The statins andMg inhibit that enzyme. Large trials have consistently shown that statins,taken by subjects with high LDL-cholesterol (LDL-C) values, lower its bloodlevels 35 to 65%. They also reduce the incidence of heart attacks, angina andother nonfatal cardiac events, as well as cardiac, stroke, and total mortality.These effects of statins derive less from their lowering of LDL-C than fromtheir reduction of mevalonate formation which improves endothelial function,inhibits proliferation and migration of vascular smooth muscle cells andmacrophages, promotes plaque stabilization and regression, and reducesinflammation, Mg has effects that parallel those of statins. For example, the enzymethat deactivates HMG-CoA Reductase requires Mg, making Mg a Reductasecontroller rather than inhibitor. Mg is also necessary for the activity oflecithin cholesterol acyl transferase (LCAT), which lowers LDL-C andtriglyceride levels and raises HDL-C levels. Desaturase is another Mg-dependentenzyme involved in lipid metabolism which statins do not directly affect.Desaturase catalyzes the first step in conversion of essential fatty acids(omega-3 linoleic acid and omega-6 linolenic acid) into prostaglandins,important in cardiovascular and overall health. Mg at optimal cellularconcentration is well accepted as a natural calcium channel blocker. Morerecent work shows that Mg also acts as a statin." Why bother taking thepharmaceutical company junk when magnesium works better? Iam reminded of the story of the boiling frogs. In biology, there is a famousexperiment using frogs. A frog suddenly dropped into hot water will jump outinstantly! Saving his life. On the other hand, a frog placed in warm water willenjoy the warmth and not jump out. If the heat is slowly increased to higherand higher temperatures, the frog will unknowingly cook to death. In thisrespect, we are like boiling frogs, slowly dying of an unknown and unrecognizedthreat. We responded as a nation instantly to the Al Qaeda attack on America.We are very good at this, but we are dying at the rate of a 9/11 every day fromhigh calcium/low magnesium and cant see it. Do you enjoy the warmth? More.I am 64 years old and my blood pressure is 100/60. Who cares what the othercardiac risk are when one has this "teenager" blood pressure! I dokeep my salt, carbohydrate and fat intake low and never smoke or drink. I dotake 500 mg of magnesium as magnesium taurate every day and I am notoverweight, but cant stand to sweat, so I dont work out, although I regularlydo manual labor on my central Texas ranch. Enough said? Ifyou are on cardiac drugs and decide to do natures magnesium plan, then youneed the help of a willing-physician (good luck) to do it carefully. However,the best thing to do first is read "TheMagnesium Factor" by Mildred S. Seelig, MD, MPH and Andrea Rosanoff,PhD. On pages 77 through 84, they state the following (much abbreviated) plan: Read Dr. Seeligs book before taking any major action. Make certain that you have primary hypertension. Trust your doctor on the immediate need for drugs, but start with magnesium for the long term. Consider metabolic syndrome X (other low magnesium deficiency symptoms). They will likely vanish too. Be careful if you are using potassium sparing diuretics or beta-blockers, because potassium can go dangerously high (or low if on thiazide or some of the stronger loop diuretics). Determine your potassium and magnesium levels. Use red blood cell testing or Exatest for magnesium. Replenish your potassium and magnesium levels gradually. Over the following few weeks, gradually lower your medication. Consider a good multi-vitamin, multi-mineral supplement, and increase magnesium and potassium intake to high doses gradually. If this works, but insufficiently, try alternate methods of magnesium administration. If diarrhea develops, control it immediately using these tips. Again, read Dr. Seeligs book before taking any major action. Addto that the following lesser known facts. Inflammation is a silent killer. Oneof the most significant markers, or indicators, predictive of who will get aheart attack is a substance known as C-reactive protein. C-reactive protein isa marker of chronic inflammation, which is a primary indicator of heart attackand diabetes risk. C-reactive protein management is a major goal ofpharmaceutical drug pushers. It is a marker of "inflammation", not acause of heart attacks. Clearly, inflammation and fibrosis are involved. Thathigh magnesium blood levels is associated with low C-reactive protein andreduced cardiac inflammation is one of the most carefully guarded secrets ofhealth. The effect of magnesium on reducing C-reactive protein and inflammationcould only have been reported by researchers having a vested interest inimproving peoples health, and not improving corporate income. This is exactlywhat happened, and this critically important work was first published in 2002by the team of F. Guerrero-Romero and M. Rodriguez-Moran working at the MedicalResearch Unit in Clinical Epidemiology, General Hospital of the Mexican SocialSecurity Institute, Durango, Mexico. Do you really believe that Pfizer wouldsupport and publish such research? Not me! The abstractfor the Guerrero-Romero and M. Rodriguez-Moran article reads:"OBJECTIVE: To examine the association between serum magnesium levels andC-reactive protein (CRP) in non-diabetic, non-hypertensive obese subjects.DESIGN: Cross-sectional study. SUBJECTS: A total of 371 subjects, 101 men and270 women. Of them 138 lean (37.2%), 133 (35.9%) overweight, and 100 (26.9%)were obese, matched by age. MEASUREMENTS: Fasting and 2 h serum glucosefollowing a 75 g oral glucose load. Fasting serum total cholesterol, HDL- andLDL-cholesterol, triglycerides, C-reactive protein (CRP), albumin; andmagnesium levels; urinary protein excretion; body mass index (BMI),waist-to-hip ratio (WHR), and blood pressure. RESULTS: The presence of CRP wasdocumented in four (2.9%) lean, 13 (9.8%) overweight, and 20 (20.0%) obesesubjects, and decreased magnesium levels (equal or less than 1.8 mg/dl), in 2(1.45%) lean, 7 (5.2%) overweight, and 19 (19%) obese subjects. The lowestserum magnesium levels and the highest CRP concentrations were documented inthe obese subjects. Twenty-three (82.1%) of the subjects with low serummagnesium (five overweight and 18 obese) showed CRP concentration equal or morethan 10 mg/l. There was a graded significant decrease between CRP concentrationand serum magnesium levels (r = -0.39, P = 0.002). The odds ratio (CI95%)between magnesium and CRP adjusted by age, sex, BMI and glucose tolerancestatus for the subjects within the low quartile of magnesium distribution was2.11 (1.23-3.84). CONCLUSION: The results of this study show that low serummagnesium levels are independently related to elevated CRP concentration, innon-diabetic, non-hypertensive obese subjects." More.You know what mitochondriaare? They are the energy source of the cell. Without functional cellularmitochondria, the cell cools to room temperature and dies. If too many cellsdie, the organ dies. Consider the human heart. We need to do everythingpossible to keep our heart cells mitochondria healthy. Certainly we shouldntpurposefully spear them with tiny daggers to kill them. Right? Low magnesiumand high calcium creates tiny spears that kill the mitochondria from within.Remember Dr. Burt Silver, owner of Exatest.com,the intracellular magnesium testing company? In 1975 he showed in this originalreport that this exact situation occurred. Too much calcium in thepresence of too little magnesium forms crystals that are mitochondria-killingspears. In the 3,000 reference 1980 book "Magnesium in Health andDisease" by Dr. Mildred S. Seelig, MD, (soon to be featured at the Magnesium Water site by Paul mason), BertSilver and L. A. Sordahl shows microphotographs of these tiny calcium"spears", and that article is here.How about a tasty double cheese pizza for supper? Served hot with hundreds ofbillions of tiny heart-killing mitochondria-killing calcium spears! Soundsdelicious to me! Moreon what causes a lethal heart attack, at least the calcification of heart andarterial tissues that leads to most lethal heart attacks. Fibrosis is anotherfactor. In 1997, EmileMohler MD, et al. at the University of Pennsylvania, published anarticle concerning a "bone building" protein found in calcifiedaortic valves. Mohler and colleagues found "osteopontin", a proteinthat makes up the molecular scaffolding to which calcium sticks in theformation of bone, in calcified hearts. "Were the first group, to myknowledge, to directly isolate osteopontin in calcified valves," notesMohler. "Identifying the molecular mechanisms underlying ossification ofvalves could lead to novel therapies to prevent or treat valve disease."In addition, the work may help to determine how calcium deposits form in thearteries of people with atherosclerosis and other vascular diseases. Cardiacvalve calcification often results in obstruction of blood flow, whicheventually leads to valve replacement. Collagen and specific bone matrixproteins are thought to provide the framework for ectopic tissue calcification.Osteopontin was present in both heavily and minimally calcified aortic valvesand absent in noncalcified aortic valves. Osteopontin also localized withvalvular calcific deposits, and macrophages were identified in the vicinity ofosteopontin. These results, in addition to showing that osteopontin is presentin calcified human aortic valves, suggest that osteopontin is a regulatoryprotein in pathological calcification. OK. Sounds interesting. George says, Iwonder if magnesium... So, I searched PubMed. If we go to this Japanesegroups work on osteopontin formation in kidneys, we find thatosteopontin is eliminated when magnesium supplements are given. This should notbe too difficult to understand and interpret in terms of cardiology too.Although osteopontin is absolutely necessary for bone formation, osteopontinformation in soft tissues, like in the heart and arteries as well as thekidneys, leads to deposition of calcium, which leads to narrowing of arteries,heart attacks, kidney disease and a wide variety of calcification healthissues. A very popular book is The CalciumBomb which proposes nanobacteria as cause of calcium buildup in cardiactissue. Perhaps this is true, but is osteopontin buildup the mechanism by whichnanobacteria construct their calcium shells? If yes, then magnesium may likelyprevent their buildup. Theonly other agent that I know of that inhibitsosteopontin formation in soft tissue (but annihilates hypercalcemia, restoresbone and generally heals tissue injuries) is gallium,an element that is normally found in the human to the extent of less than 0.2milligrams. Gallium has clinical use in treating some seriousbone loss diseases. I use a lot of gallium nitrate in thetreatment of a bone/joint condition in horses called "naviculardisease" with great effect. I have also postulated that gallium isan essential nutrientfor survival of the 21st century. Gallium nitrate is effective in treating anotherwise incurable horse disease. I also give my horses large amounts ofmagnesium dietary supplements. My old horses run around like spring chickens!Magnesium and gallium really make them act young. Gettingback on track, we remember that mitral valve prolapse canbe totally reversed in about one year with daily supplements of 1,000mg of magnesium as magnesium orotate. Also, look at these graphics of "calcifiedhearts" on Google. To me, if your physician has told you that youhave calcium deposits in your arteries and/or heart, you would be totallyinsane not to take about 1,000 mg of magnesium every day, twice what I musttake, in hope that in about a year you might become free of this silent killer.The benefits are believed to start immediately, but complete clearance willtake a while, perhaps a long while. If you must take that much supplementalmagnesium, be prepared for gut problems, and study tips on this page on how to deal withmagnesium-induced diarrhea. Evensnake keepers know too much calcium will cause heart failure. Here is Freds story.He was a python that died of a calcified heart. Apparently, some snakes areextremely sensitive to even small amounts of supplemental calcium, and vitaminD. The Lethal Hypothyroid - LowMagnesium Axis Near thebeginning of this essay, I reported that hypothyroidism can cause depressionand that it must be treated and/or ruled out as cause of depression. Now thereis clear evidence as shown in this figure that one of the thyroid hormones (T4)is directly related to magnesium serum levels in major depression, particularlyin women. For more information see this clinical report.Levels below 0.9 mMol magnesium are considered low. We can extend thisobservation to say that hypothyroidism causes low serum magnesium, whichappears to be the actual mechanism by which hypothyroidism causes depression.Interestingly, hypothyroidism does not affect calcium blood levels. Lowmagnesium caused by hypothyroidism also contributes heavily to cardiovasculardisease and it must be corrected for longevity. Thesimplest of all clinical tests, the use of a glass (not digital) thermometerheld in the mouth far back under the tongue remains the gold standard fordetecting hypothyroidism. The temperature should be taken over a full tenminute time and repeated for about a week each morning before warming up. Anoral temperature below 97.5 degrees should be considered an 80% probability ofhypothyroidism. While men can check their temperature any day of the month,women have a menstrual cycle that must be considered. The only accurate time ofthe month for determining true body temperature (as it relates tohypothyroidism) in women is while they are not menstruating. Some of the signsof hypothyroidism include: Fatigue, depression, difficulty concentrating,difficulty getting up in the morning, cold hands and feet or intolerance tocold, constipation, loss of hair, fluid retention, dry skin, poor resistance toinfection, high cholesterol, psoriasis, eczema, acne, premenstrual syndrome,loss of menstrual periods, painful or irregular menstrual periods, excessivemenstrual bleeding, infertility, fibrocystic breast disease, and ovarian cysts.There are many good web pages on thyroid disease, and I encourage you toexamine them. The Father of thyroid disease research is Broda O. Barnes, MD andhis web site is at http://www.brodabarnes.org/.His book "Hypothyroidism:The Unsuspected Illness" is both a standard and a classic, and itreports that untreated hypothyroidism is the cause of enormous amount ofmorbidity and mortality, often through heart attacks. Infact, Dr. Barnes research suggested that many heart attacks have a hypothyroidcomponent, apparently via lowering magnesium serum levels, strongly suggestingthat the American HeartAssociation figure cited by Seelig and Rosanoff is, while accurate, itand its derivatives are misleading. The point that Dr. Barnes made in hisChapter 11 is that although few people died of heart attacks pre-1900 (as isclearly shown by the misleading American Heart Association figure), they diedof infectious diseases, usually tuberculosis, before they had a chanceto die of heart failure. His review of 70,000 autopsy records of Graz, Austriashowed that a very large number of people dying early of non-cardiac deathsalso had the same cardiovascular lesions and cholesterol buildup that are knownto cause heart attacks and death. They simply died of something else earlier,and theoretically would have died of heart failure later. Since Dr. Barnespractice primarily addressed thyroid issues, he was baffled as to why hispatients did not develop heart disease. He looked into his patients records anddiscovered the cause of many heart attacks! On his page 180, he showed that itwas easy to prevent heart attacks in his patients - if and only if - hypothyroidissues were solved. His Table 1 shows the number of heart attacks in twodifferent but essentially equivalent populations. The groups showed sex and ageof patients, number of his patients treated with thyroid, total man-yearspatients were treated with thyroid, the resultant expected coronary cases(heart attacks) according to the Framingham study (not treated with thyroid)and coronary cases in the thyroid-treated patients of Dr. Barnes. He alsoshowed that if hypothyroidism were corrected, high cholesterol issues wouldalso go down. Further, he showed that hyperthyroidism would even further lowercholesterol! He strongly emphasized that only whole thyroid (Armour thyroid) was of value inthis regard, suggesting that not everything is known about "thyroid".Any doubt that hypothyroidism does not have a major role to play in heartattack? Accordingto Barnes, if T4 thyroid hormone is low and you have a low magnesiumconcentration, you are in deep trouble and you must resolve your thyroid issuesfirst and keep them corrected for the rest of your life, or it will beshortened, and perhaps greatly shortened. Why? Here is how I see it. Thyroid T4governs the blood levels of magnesium, which in turn governs cholesterollevels, which in turn governs the incidence of heart attacks. I knew an elderlywoman that took large amounts of magnesium for her heart for many years, andshe limited her intake of sodium chloride by only using potassium chloride.Sounds like a good idea, but in the United States Mortons Salt Substitute(potassium chloride) does not contain iodine like other salts, which in theUnited States is a primary source of dietary iodine. She died of a massiveheart attack, as one would predict for low iodine-induced hypothyroidism,resulting in low serum magnesium. Remember that hypothyroidism can beessentially symptom-less, other than for the low body temperature.Interestingly enough, the thyroid researchers indicate that this is a typicaldeath-pattern for elderly women. Elderly women are often hypothyroid and neverknow it, and they die of cardiovascular disease disproportionately to men ascan be seen here.Only upon correcting thyroid issues will one see efforts in raising magnesiumconcentrations and eliminating depression succeed and cardiovascular diseaserelated death prevented. I know of no research to show that low magnesium wouldcause hypothyroidism, but anything is possible. Whatcauses hypothyroidism? Many things including some psychiatric drugs such as lithiumand tricyclicantidepressants. I encourage you to avoid these drugs for obviousreasons. In the United States, our consumption of iodine and magnesium are bothlow and, if iodine is very low (considerably under 150 micrograms per day - theRDA), then hypothyroidism is likely caused by low iodine intake. Thus, onecould extend the argument to say that low iodine causes low magnesium, whichcauses... . This single cause of low magnesium may very well explain somefailed clinical trials, wherein magnesium supplementation failed to preventheart attacks. For example, if hypothyroid patients were equally represented inboth the placebo- and active-treated groups, then hypothyroidism would haveprevented magnesium supplementation from having the desired and predictedbeneficial effects. Inthe United States, high iodine (over 1 milligram per day by many reports), mayalso cause hypothyroidism, and may also cause hyperthyroidism. Too muchiodine can raise body temperature, and may either mask hypothyroidism or cureit. In Okinawa, Japan, hypothyroidism from too much iodine doesnt occur untilintake is in the 10 to 20 milligrams or higher per day range. Okinawanscommonly have an intake of iodine in this range from their custom of ingestinglarge amounts of kelp, which is the best food source of iodine. They also havemuch higher intake of magnesium and taurine (also from kelp), and live to be120 years of age with vastly greater frequency than short-lived Americans. Theyeat a lot of conchwhich is a major source of taurine. Clearly,we have much to learn about the optimal intake of iodine to preventhypothyroidism, and much to learn about how to prevent hyperthyroidism from toomuch iodine. In my humble opinion, I believe that the principal cause of heartattacks is an inadequate supply of both iodine and magnesium. What we mustunderstand in this instance is that in the United States, physicians tend totreat symptoms without much consideration of underlying causative factors, likehypothyroidism. Yes, low magnesium / high calcium remains the principal causeof lethal heart attacks, but we must dig deeper and find out what is causingthe low magnesium issue. HoHum George, you are really getting a little on the hysterical side. What youare saying has been known, more or less, for a hundred years in homeopathy. Inhomeopathy, magnesium is suitable for a large number of CHEST symptoms,especially pain, palpitations and heart pain. Just go to this page andsee what homeopaths have known about magnesium and chest illnesses since theydiscovered Epsom Salts in England over a hundred years ago. Ho Hum. This"magnesium for hearts" stuff is boring it is so old. But! It hasbecome hidden and has fallen into disuse, while it should have been made intonational and international health policy by our leaders. Our only solace isthat they die of heart attacks too. Other Cardiac Risk Factors Thereas some other dietary factors which can contribute to lethal heart attacks. Toolittle synthesis of CoenzymeQ10 (CoQ10) in the liver (or too little consumption of supplements ofCoQ10), and too little fish oil (Omega-3Essential Fatty Acids), and especially toolittle copper contribute to death from heart failure as shown in thisreview of the copper/heartliterature. These three nutrients are vital in aging, and areparticularly necessary in aging/stressed hearts. Salmon is high in both copperand omega-3 EFAs, and it is difficult for me to see which of these twonutrients is the more important in preventing heart attacks. Perhaps it is bothtogether that makes salmon such a wonderful heart food. According to Charles Webersreview, women may have greater resistance to heart attacks due toestrogens ability to keep copper levels from falling. Copper works to keepconnective tissues pliable and properly functioning. Some food sources ofcopper are also listed here, butmy favorite is liver. Some scientistshave devised a regimen of "metabolic therapy" to protect thesenescent (aging) heart against stress. Their metabolic therapy involvestreatment with CoQ10, alpha lipoic acid, magnesium orotate, and omega 3polyunsaturated fatty acids with physical exercise and mental stress reduction.They found that damage to mitochondrial DNA from aging was less predictive ofimpaired response to stress (death) than age alone. They concluded that theaging heart has a diminished capacity to recover from stress that is notreadily predictable by cardiac content of intact/damaged mitochondrial DNA, andthat this recovery can be improved by metabolic therapy combined with physicalexercise and mental stress reduction. Realize that low magnesium is THE majorcontributor to inability to withstand stress, and that low magnesium must becorrected to survive with an aging heart. LestI trick you into believing that magnesium is the cure-all, I want to bring upsomething that I discovered in 1981 while doing my zinc lozenge and common coldresearch. Dr. William W. Halcomb and myself discovered that zinc could be usedto stop, prevent and effectively treat angina pectoris, even when severe.Although we discovered this effect in 1981, we never published it except on theweb at http://coldcure.com/html/angina.html.In 1985,serum zinc was shown to be low in unstable angina. An old man (seemed old to meat the time) came into our clinical trial with a bad cold and he received zincgluconate lozenges for his cold. He was taking 23 mg of zinc each two wakefulhours. His cold did not benefit from zinc treatment, but his angina pectoriswent away for the first time in over 15 years. He had been on a railroaddisability and was considered totally disabled. He had been unable to walkacross a room without major chest pain for many years. He had previously used nitroglycerinlike candy all day long with some benefit. While taking zinc, he required zeronitroglycerin. He had no cardiac pain for the first time in 15 years and wasecstatic. He had always wanted to go snow skiing in the Rockies, and he did andbrought us back home movies! We had a big beer bust. Life for him was good. Welost track of him because he moved to Chicago where I last heard he had a newjob working for a railroad. I have several other friends that took zinceffectively for angina, and Dr. Halcomb immediately made it part of hisclinical practice with success, finding that on average 160 mg of zinc a daywould prevent over 50% of cases of angina pectoris. Now, with people weighingso much more, a better dosage would be 2.2 mg of zinc per kilogram of bodyweight (1 mg zinc per pound of body weight). One man, the father of a racingcar friend of mine, was a large man aged 76 with horrible angina. He took 160mg zinc a day for a week, and it did not help him, so he took 300 mg. (Old racecar driver trick - if something wont work, use a bigger hammer.) In 30 days ofzinc treatment at 300 mg per day, his angina suddenly subsided and he was painfree for the first time in many years. He became active again and startedriding his sons horse. He took the horse on a cattle drive and rounded up cowsfor several days. He was a happy man like that for about a year. Then, he had acardiologist appointment, and although he was in vastly better health thanever, his cardiologist forced him to stop the zinc since it was known to"slightly raise bad cholesterol" in younghealthy students. About a month latter he developed congestive heartfailure and died. We know little about the biochemistry of zinc and cholesterolin older, unhealthy people such as those with angina pectoris. However, it isclear that there is more depression and cardiac failure in elderlypeople with low zinc. Seems to me that we probably need to look at zincmuch more closely for cardiovascular health. How can zinc work? Who knows, butzinc in these doses over extended periods of time would antagonize iron, abuildup of which is well known to be injurious to the heart. People believethat loss of iron in menses protects menstruating women from heart disease, andthat once they become menopausal, that benefit is lost. Supplements of zinc tocounter iron in the aging heart seem reasonable. I think a daily dose of 2.2 mgper kilogram body weight would work very well to demonstrate the effect of zincin treating angina pectoris, if given for a minimum of 7 to 30 days. We usedzinc gluconate in our clinical trial, which usually upsets the stomach if dosesare greater than 20 to 50 mg per dose. However, if a person is zinc deficient,the upset stomach probably will not develop. I certainly would have periodiczinc blood levels done to insure that increases beyond the normal upper rangedo not occur because they can be immunosuppressiveif taken out of the normal range over a one month period. Zinc. A wonderfulelement, which is also removed from whole grain during the refining process tomake "depleted" wheat. Look at this data. Thegrain refiners were / are really looking out for the pharmaceutical companies.Dr. Halcomb and I decided to publish our thoughts about high dose zinc to cureangina pectoris (and by implication arteriosclerosis caused by cholesterolbuildup in arteries) in Medical Hypotheses, a medical journal dedicatedto new ideas that have sound theoretical support. We submitted our article andit was approved the same day we submitted it. Perhaps you dont see thesignificance of that timely acceptance, but it is close to miraculous to me.Our accepted article is here.Stupidity Runneth Over Inthe United States, Uncle Sam has officially (and stupidly) proclaimed that 1200mg of calcium and 400 mg of magnesium to be necessary daily intakes (RDA). Isay, yes that is true only for doctors and hospitals that benefit from you andme having heart problems! (Remember that this is a multi-trillion dollarindustry.) Seems to me that if you dont want your heart and arteries tocalcify and turn to stone, take 400 to 600 mg of magnesium a day, never takecalcium supplements, and carefully watch your dairy consumption (particularlycheese). Leave it to Uncle Sam to kill us all before we start drawing SocialSecurity checks! Additionally, this screw up causes most of the chronic illhealth in America today, creating vast wealth for pharmaceutical drug pushers.Take a look at this list of lowmagnesium symptoms (doctors call them diseases). Yes, folks, just keepspearing your mitochondria with calcium crystals! For more information onchronic illnesses treatable by magnesium, read the book by Dr. Norman Shealy,MD, PhD titled "HOLYWATER, SACRED OIL; THE FOUNTAIN OF YOUTH". Here is his index todiseases that are magnesium deficiency symptoms, or are responsive to magnesiumtreatment (on pages) of his book. Allergies- 151, 159, 146 Alkalyzing Spondylitis- 164, 165 Age Reversal- 137, 138, 143, 147, 161, 162, 163, 184, 201, 203, 207, 211, 212, 213, 214 thru 217 Angina Pectoris- 119 Anxiety- 118 Anorexia- 119 Arrhythmia- 119 Arthritis- 166,171,177, 181, 203, 146 Attention Deficit Disorder- 118, 119 Asthma- 119 Benign Prostatic Hypertrophy- 119 Atherosclerosis- 119 Bulimia- 119 Babies (problems)- 179, 201 Bug Bites- 202, 203 Burns- 202 Bronchitis (chronic)- 119 Cancer- 119, 161, 163, 175, 181, 182 Cardiomyopathy- 119 Cellulite- 147, 149 Cartilage Restorer- 202 Chronic Fatigue- 119, 151, 164, 168, 170, 171, 174, 181, 184 Cirrhosis- 119 Congestive Heart Failure- 119 Confusion- 118 Constipation- 118 Depression- 118, 119, 123, 181 Detox- 150, 153, 147, 171 Diabetes- 119, 121, 178, 179, 180, 184, 185 Diabetic Neuropathy- 178, 179, 180 Diarrhea- 118 Dry Skin- 202 Eclampsia or Pre-eclampsia-119 Edema (water retention)- 170 Emphysema- 119 Faintness- 118 Fibromyalgia- 119, 123, 148, 150, 153, 175, 176, 181 Gall Bladder Infection and Stones- 119 Gastrointestinal Problems- 156, 201, 203 Headaches- 119, 152, 167 Hearing Loss- 119 Hair Color Restorer- 140, 202 Hyperactivity- 119, 179 Heart Attack- 119 High Cholesterol- 119 Hypertension (High Blood Pressure)- 120, 122, 161, 185 Hyperventilation- 118 Hypoglycemia- 119 Incoordination- 118 Ingrown Toenails- 180 Insomnia- 147, 160, 169, 171, 174, 180, 181, 184 Immune Deficiency- 119 Infections (Viral & Bacterial)- 119 Intermittent Claudification-119 Interstitial Cystitis- 149, 152 Kidney Stones- 119, 171 Lumbar Scoliosis- 149 Myocardial Infarction (Heart Attack)- 121 Migraine- 119, 122 Mitral Valve Prolapse-119 Multiple Sclerosis- 166, 174, 178, 181 Muscle Spasms- 147, 172, 173 Menstrual Cramps- 152 Narcolepsy- 162 Osteoporosis- 119, 123, 124, 202 Pain (all types)- 147, 146, 148, 150, 154, 163, 164, 167, 169, 170, 171, 172, 173, 174, 177, 178, 179, 181, 184, 203 Panic Attacks- 119, 124 PMS- 119 Poor Memory- 119 Psoriasis- 148, 175, 176, 180, 181, 182 PVCs- 120 Reflex Sympathetic Dystrophy- 121, 124 Seizures- 119 Skin Rash- 147, 148, 170, 171, 173, 175, 176, 180, 181, 203 Strokes- 121, 178 Stress- 203 Sunburn- 147, 153, 180, 202 Tinnitus- 119 Toe Fungus- 180 Tooth and Gum Problems- 160 Vertigo- 119 Water Retention (Edema)- 170 Weight Loss- 139, 147, 159, 161, 181, 184 Wounds & Welts- 151, 154, 174, 177, 179, 184, 202, 203 Wrinkles- 137, 147, 150, 151, 164, 174, 175 Yeast Infection- 202 Clearlythe response to solving most of Americas health problems with an inexpensive,readily available nutrient will be the banning of all sources of supplementalmagnesium by the U.S. FDA in the interest of "protecting our health",unless we take action and influence the Congress. Clearly the pharmaceuticaldrug pushers have much to loose. They are responsible only to theirshareholders (see the movie TheCorporation for the low down on this pathological pursuit of profit andpower), and the combination of the FDA wishing to protect its regulatory turf,and protect pharmaceutical company income (regardless of the human and animalconsequences - because the pharmaceutical drug companies offer really greatsalaries for ex-FDA officials) is really overwhelming. Dont believe me? Herecomes CODEX!Read it and weep. Sorry. Physiciansand researchers will want to review some of Drs. Seeligs and Rosanoffs 1,512references in their book, TheMagnesium Factor bearing witness to their findings. Ihave been puzzling over the relationship of Omega-3Essential Fatty Acids to magnesium in the cardiac risk issue. Here isan interesting link - I think. We know that glutathioneis important to increasing or maintaining or enhancing intracellular magnesium,but it is an expensive supplement. We also know that Omega-3 Essential FattyAcids (from fish oil) are important to cardiac health, they relax cells likemagnesium does. Now, there is a link between Omega-3s and glutathione, whichtranslates into a need for Omega-3 Essential Fatty Acids to maintainintracellular magnesium. See this Russianarticle . I do know that my bronchitis and arrhythmias are muchrelieved with supplements of Omega-3s, and now I can see why. Also, in 1985 Gallandshowed that in latent tetany (a magnesium deficiency disorder), Omega-3 EFA wasalso low. Exercise Perhapsevery person that has seen a psychiatrist for depression is told to exercise. Iwonder how many follow the doctors advice. Exercise is good for you, but nottoo much or it will stimulate appetite. Why? The fact is that exercise changesthe way our cells react with insulin.Exercise makes our cells less resistant to insulin, and therefore more able tohold magnesium. Exercise is mandatory for diabetics for the same reason. Howmuch exercise? Well, the doctors suggest brisk walking, and we all know that wefeel better after a walk. But the good feeling doesnt last. Why? Quite anumber of papers show that resistance training for insulin resistance is betterthan aerobic training. Resistance training is referring to muscular exercises,body building and heavy, but not exhausting exercise. If you just do a bicepcurl, you immediately increase the insulin sensitivity of your bicep. Walkbriskly, and you immediately increase the sensitivity of your legs to insulin.Just by exercising you are increasing the blood flow to that muscle anddecreasing insulin resistance, and improving retention of intracellularmagnesium. It has been shown conclusively that resistance training, I.E. musclebuilding, will increase insulin sensitivity. If we are so depressed that wecant exercise, then we need to have someone exercise us, perhaps with anelectric cattle prod to get us up off our butts! Get a menial job stackingboxes in a hardware store, stack lumber in a lumberyard, walk goats up amountain, walk to the top of every hill and mountain in your state, one perday. Go to the gym and lift weights all day. Swim upstream in a fast movingcreek. Think about the astronauts with their enormous loss of muscle mass (30%per flight) and viciousloss of magnesium. What do they do? They body-build with a vengeance,and so must we. They will sometimes exercise while on TV being interviewed.What kind of exercise? Depends on the person. Exercise enough that you sleepwell at night. Exercise enough so that you are truly tired at the end of a day.Do fifteen minutes of exercise? OK, but do it each 30 minutes that you areawake! See what I mean? EXERCISE as if your life depended on it! I recentlyhired a laborer that very much impressed me. I had a large gully on a terracebehind my house and I needed to have the gully up that terrace slope filled inwith soil. I hired a Mexican laborer, and with a shovel and wheelbarrow, thatmiddle-aged man filled in that gully with an entire 12-ton dump truck of soilin 8 hours. How did he do it? One wheel barrow at a time walking up the hill.Can you imagine being nearly fifty years old and pushing a wheel barrow full ofdirt up a hill all day long and then saying, "Para nada. Ése no es ningúnproblema. Gracias por el trabajo." He went home to a beer. Me? I wasexhausted from watching him work! Remember what you are trying to do, which isrestore your bodys cells sensitivity to insulin, which restores their abilityto absorb and retain magnesium. How long will it take? Maybe six months, butsuch is a short time for such an enormous benefit. Dr. Mildred S. Seelig, themagnesium guru, points out the too much exercise will cause a loss ofmagnesium, but I think the benefits of exercise outweigh this problem becausewe can simply take more magnesium to compensate. Saltis a subject of some controversy right now, particularly as it applies toexercise. There is one vocal school that says too much salt (sodium chloride)causes hypertension, and another that disagrees. Some say thatour high ratio of sodium relative to potassium intake is causing hypertension,a point of view which has support at the NIH,and is my opinion too. The NIHs point being that increasing fresh vegetableintake (naturally high in potassium) and lowering salt (sodium chloride)ingestion reduces hypertension. For data comparing the sodium and otherelectrolyte ratio changes from the year 1900 and 2000 see this link in thispage. Others say that our potassium to sodium relative intake is dangerouslylow, and suggest increasing our intake of potassium chloride. I prefer to leavethis debate in the hands of your physician, who after examining you can make anintelligent recommendation. Why? Too little dietary sodium intake will causedeath in climates where the temperature is very high due to loss of salt in thesweat from excessive exercise or hard labor. Anyone that has tasted sweat willnotice that it has a salty taste, clear evidence that one is loosing sodiumand, to a lesser extent, potassium through the sweat. On the other hand, peoplewith kidneydisease may not be able to excrete sufficient sodium to clear excessdietary sodium, and will need a low sodium diet (a natural food diet and not aprocessed foods diet). The RDA for sodium is 2,400 mg per day (approximately6,000 mg salt or 1 teaspoon of salt), while the estimated RDA for potassium isbelieved to be about 4,000 mg. In 1900 it was 6,000 mg, a time of very lowincidence of heart problems. Nutritionists and physicians that proclaim a ZEROadditive salt intake to be generally good advise actually provide deadly advisefor people who sweat excessively due to exercise or labor in high heatconditions. Also, the main cause of death from protracted diarrhea is loss ofsalt (sodium chloride). Perhaps part of the confusion arises in our culture dueto our addition of iodide to table salt but not to potassium chloride.Consequently, the benefits of iodide (iodine) in table salt sometimes (nearlyalways in elderly women) causes people consuming lots of table salt to bebetter off cardiac-wise than people not consuming iodide (iodine) throughavoiding table salt and using a salt substitute (potassium chloride) instead.The answer? For me it is to avoid sodium chloride (table salt) like the plague,and supplement with iodine. Areyou a pig? My father had more than 1000 white yorkshire pigs in the Rio GrandeValley of Texas when I was growing up. We were looking for cheap foods for themand he found a shrimp packing plant that harvested fresh Gulf of Mexico shrimpand breaded them and packaged them for retail sale. The plant gave ustruckloads of fresh breaded shrimp that had become contaminated, usually by ithaving fallen off of the conveyor belt. By all accounts that was still asuitable source of fresh protein for pigs. The pigs loved it and ate is withgreat glee. A few months after starting that "proteinsupplementation" program, they started to die. First just a few, then asthe days went on, more died, a week later many died, then most of them died. Atsome point we involved the County Agriculture Extension Agent and he wasterrified that our pigs had a terrible disease. He called for help andeventually we had Food and Drug Administration people, USDA people, TexasDepartment of Animal Health and a bunch of other County State and Federalregulatory and investigative people on our property trying to figure out if acounty-wide quarantine was merited. The newspaper and radio and TV people wereall there announcing the mystery death of thousands of pigs. What was killingthe pigs? Scientists from the USDA reported that sodium chloride in thebreading on the shrimp killed our pigs. Remember, we are very similar to pigsinternally. This should make us consider whether or not salt is good for us. Onthe other, other hand, injected potassium chloride instantly kills by stoppingthe heart; and in fact, IV potassium chloride is used to execute criminals. A friend of mine onMarthas Vineyard felt that if a little bit of potassium chloride was good,then a bunch would be better. She took an entire teaspoon of pure potassiumchloride salt and it "melted a hole through her stomach". Sheimmediately caused herself to throw up and probably saved her life in theprocess, at least she saved herself a trip to the emergency room. Enough said?I repeat! Potassium chloride must never be consumed straight! It must always bediluted in water or used as a seasoning in food and judiciously used. Ihave experimented with judicious amounts of potassium chloride (1/4 teaspoon)dissolved in an 8-oz glass of water to lower my pulse rate. Good idea?Actually, yes, it is a very good idea! If our pulse rates can easily be loweredby reasonable intake of potassium chloride (in a glass of water or by simplysubstituting it for regular table salt), then such seems to indicate adeficiency situation that has been corrected. However, remember that metabolicshock is hyperkalemia!Mortons Salt Company makes a mixture of sodium and potassium chloride saltthat is increasingly popular. Is it safe? Yes, I think so because it is anequal 50/50 mixture of sodium and potassium salts and it has iodide (iodine) init for heart and thyroid protection. However, many people eat processed foodswhich are already high in sodium chloride salt, and their intake may be so highthat use of Mortons Salt Substitute (nearly pure potassium chloride) isabsolutely necessary (but only when iodide or iodine (150 mcg or more/daily )is otherwise supplemented). The healthiest ratio of sodium to potassium isabout 1:30 (the ratio found in Americans in 1900), not the 2.5:1 ratio oftoday. Notice that MortonsSalt Substitute label asks the user to consult with a physician beforeusing, because it has no iodide or iodine which is vital to preventing heartdisease and thyroid issues, and must be supplemented otherwise. Limiting saltintake is only one of several steps necessary to reduce total sodium intake.Nearly all processed foods contain additive sodium, either as sodium chloride,or as some other food additive such as monosodium glutamate (MSG), or drugssuch as OTC antacids and headache remedies. More on reducing hidden sources ofdietary sodium here.I think the best idea for most of us is to consider additive dietary potassiumchloride to be necessary, with preference given to eating high potassiumcontent natural foods, not processed foods (very high in sodium chloride).Also, anyone that has developed muscle cramps from working in high temperaturesand sought medical advise is certain to have been told that increasingpotassium intake will help prevent muscle cramps. Consequently, both sodium andpotassium are needed in extra amounts in high heat, sweat conditions. However,potassium chloride must never be consumed straight! It must always be dilutedin water or used as a seasoning in food. In your decision making on potassiumand sodium intake, remember that sodium drives down magnesium and potassiumdrives it up, and that iodine deficiency will cause the exact same cardiacinjury that is caused by low magnesium and high calcium. Succeed! Depression is not a psychosis! Diagnosis Of Magnesium Deficiency Serum or blood levels of magnesium (typically found in clinical laboratories)are a total waste of blood, money and time except in acute alcoholism,starvation or diabetic acidosis. These tests have perpetuated the myth thatmagnesium deficiency does not exist, and should be made illegal due to thegrave, national-health damage caused by them. There are only three testsworthwhile: oral dosing, magnesium loading and intracellular spectroscopy,although some still like the red blood cell test. "Oral Dosing" is nothing more than giving magnesium at proper dosages and observing improvement as described in my section on Dosage". Never give toxic forms of magnesium. This test does not require a physician or laboratory tests and is considered definitive. "Magnesium Loading" is considered the standard by the few physicians who at least recognize the possibility of magnesium deficiency. The test is somewhat tedious and frustrating to patients. First one has to collect every drop of urine for exactly 24 hours. The urine is then analyzed for total magnesium and creatinine output in a clinical laboratory. Then the patient is given intravenously a specific "load" of magnesium and a second 24 hour urine is collected and tested for magnesium and creatinine. If less than 50% of the administered magnesium is excreted, this is "proof" of magnesium deficiency. In fact, if less than 20% is excreted, "borderline" magnesium deficiency is suspected. "Intracellular spectroscopy", the Intracellular Diagnostics"Exatest involves a simple, painless scraping of the soft tissues, (epithelial cells) from the floor of the mouth right under the tongue. This is an easy, non-invasive, risk-free test. The oral epithelial (surface) cells from the mouth scraping are placed on a slide and sent to a laboratory for x-ray analysis using an electron microscope. At about the same cost as the magnesium load test and much better patient compliance, this test also gives intracellular levels of magnesium, calcium, potassium, sodium, chloride, and phosphorus, as well as equally important ratios between these minerals. If your physician will or can not order this important and accurate test for you, find another physician. If you have any of the symptoms or illnesses that are being discussed on this page, it is extremely wise to have this test done. The lab is: Intracellular Diagnostics, 553 Pilgrim Drive, Suite B, Commerce Park, Foster City, CA 94404, 800-874-4804. Their price, which was quoted February of 2003, was $175.00, which they say is usually covered by insurance and Medicare. They will refer you to the closest physician capable of doing the collection. Red blood cell testing (not whole blood or serum tests) can be performed in most medical laboratories and is reasonably accurate. Perhaps the most sophisticated test of all is the ionic magnesium test developed by Drs. Burton and Bella Altura of SUNY-Brooklyn Downstate Medical School, School of Graduate Studies. Search this page for more on their research. This test measures ionized magnesium. Here is an important point from this article: "The research in Dr. Bella Alturas laboratory is focusing in the roles of cytosolic free magnesium ([Mg2+]i) and serum ionized Mg2+ in cardiovascular homeostasis and disease. Much of our recent research centers on the role of this action in womens health and disease. We have found that estrogens and progesterone play dominant roles in regulating blood and vascular smooth muscle cell levels of free Mg2+ ions. Disturbances in the menstrual cycle and menopause lead to perturbation of the normal hormonal regulation of Mg2+ in women. Certain disease processes in women, particularly those associated with cardiovascular disease, demonstrate abnormalities in Mg2+ metabolism. Much of these advances have been obtained through the use of Mg2+ ion-selective electrodes which our laboratory helped to pioneer." More... "We have found that Mg2+ regulates the state of oxidation of vascular smooth muscle membranes and generation of a variety of sphingolipids which exert vasomotor actions on numerous blood vessels in the brain and peripheral circulation. Recent findings, in our laboratory, suggest that nitric oxide generation or its inhibition plays an important role in the cardiovascular and molecular-cellular action of Mg2+. Mg2+ appears to modulate atherogenesis and blood pressure regulation via its actions on PKC isoforms and nuclear transcription via NF-kB activation or inhibition." Moreon magnesium testing at the HeadachePainFreesite. Succeed! Depression is not a psychosis! The Essentiality of Boron Boronis well known for its role in preventing urinary lossesof both calcium and magnesium. Apparently, it can raise both calciumand magnesium by about 1/3. Consequently, boron is important in recovery fromdepression; and it has the potential to reduce the amount of magnesium requiredto alleviate depression, and increases resistance to diarrhea. Boron hasrecently been found to be important in brainand psychological function. Published studies consistently show thatthe administration of small amounts of boron (2-3 mg/day) reduce the amount ofcalcium and magnesium urinary excretion. The effect of boron in preservingcritical minerals is more apparent when dietary intake of magnesium islow. In response to boron supplementation, estrogenand testosterone levels increase in postmenopausal women, which mayrestart menses. Borons function in boneformation appears to be related to magnesium metabolism. Boron alsoappears helpful in treating and preventing autoimmune diseases,such as rheumatoid arthritis. In human deficiency studies, supplementation withboron improved several parameters including mental alertness, memory, mineralmetabolism, and blood hemoglobin. Recently, the National Academy of Sciences Instituteof Medicine has set the tolerable upper intake levels for boron at 20milligrams per day, but did not establish a RDA. Along with a diet high inboron, I also took 6 to 12 milligrams of boron (Twin Labs Tri-Boron) in themorning. Many years ago, when boric acid was used as a food preservative, 500mg were found to have adverseeffects in humans causing severe gastrointestinal distress and problemswith appetite. Some important food sources of boron are shown in the followingtable. Concentrationsof Boron in Selected Foods (from: Futureceuticals) > Food Boron Food Boron (mg/100g) (mg/100g) Almond 2.82 Hazel Nuts 2.77 Apple (red) 0.32 Honey 0.50 Apricots (dried) 2.11 Lentils 0.74 Avocado 2.06 Olive 0.35 Banana 0.16 Onion 0.20 Beans (Kidney) 1.40 Orange 0.25 Bran (wheat) 0.32 Peach 0.52 Brazil Nuts 1.72 Peanut Butter 1.92 Broccoli 0.31 Pear 0.32 Carrot 0.30 Potato 0.18 Cashew Nuts 1.15 Prunes 1.18 Celery 0.50 Raisins 4.51 Chick Peas 0.71 Walnut 1.63 Dates 1.08 Wine (Shiraz Cabaret) 0.86 Grapes (red) 0.50 Noticethat almonds are high in boron. Tracy R. from Vermont called me yesterday (July12, 2005) and told me a story about her autistic 10-year old daughter. She hadhad all the problems one would expect from an autistic child. She found thatshe had some magnesium deficiency symptoms and some food intolerance symptomsas well as many other problems. The child could not tolerate magnesiumsupplements and they gave her a rash. The removal of casein, gluten, corn,chocolate, soy and citrus greatly reduced her autism symptoms. However, foodpreparation was a difficult task. As a substitute for wheat flour, she recentlystarted using almond flour. She noticed that childs autism symptoms,particularly the childs problems with food sensitivities, regressedsubstantially. When she gave 3-mg of boron daily, boron enabled the child toeat all foods that previously exacerbated autism symptoms.. When she stoppedgiving boron, the digestive problems returned. She could modulate her digestiveproblems simply by giving boron dietary food supplements. She now seesconsiderable progress in her child, and the child is now diagnosed as having"Pervasive Developmental Disorder, not otherwise specified" ratherthan autism. She sees some very positive cognitive results as well. She isimproving verbally and physically and she feels shes made a slight gain in comprehensiondue to boron supplementation. I checked Pubmed.gov for the search terms"autism" and "boron" and found zero papers. Is boron thecure for autism? Will boron cure autism? Maybe! If you test this hypothesis,please let me know what you find. Dr.James G. Penland of the Grand Forks, North Dakota United States Department ofAgriculture wrote an article entitled: Dietary boron, brain function, andcognitive performance. His article was published in EnvironHealth Perspect 102(suppl 7):65-72, 1994. His abstract reads:"Although the trace element boron has yet to be recognized as an essentialnutrient for humans, recent findings from animal and human studies suggest thatboron may be important for mineral metabolism and membrane function. To furtherinvestigate the functional role of boron in humans, measures of brain function(the electroencephalogram or EEG) and performance on several mental and motortasks were collected from healthy older men and women fed ~0.25 and ~3.50 mgboron/2000 kcal/day. When compared to high boron intake, low dietary boronresulted in changes in the EEG similar to those found in cases of generalmalnutrition and heavy metal toxicity. Performance measures (e.g., responsetime) also showed an effect of dietary boron. When compared to high boronintake, low dietary boron resulted in poorer performance on tasks emphasizingmanual dexterity, eye-hand coordination, attention, encoding and short-termmemory. Collectively, the results of these three studies indicate that boronmay play a role in human brain function and mental and motor performance, andprovide additional evidence that boron is an essential nutrient forhumans." Dr.Penland followed up with a secondreport, the abstract of which reads: "Boron (B) nutriture has beenrelated to bone, mineral and lipid metabolism, energy utilization, and immunefunction. As evidence accumulates that B is essential for humans, it isimportant to consider possible relationships between B nutriture and brain andpsychological function. Five studies conducted in our laboratory are reviewed.Assessments of brain electrical activity in both animals and humans found thatB deprivation results in decreased brain electrical activity similar to that observedin nonspecific malnutrition. Assessments of cognitive and psychomotor functionin humans found that B deprivation results in poorer performance on tasks ofmotor speed and dexterity, attention, and short-term memory. However, littlesupport was found for anecdotal reports that supplementation with physiologicamounts of B helps alleviate the somatic and psychological symptoms ofmenopause. Parallels between nutritional and toxicological effects of B onbrain and psychological function are presented, and possible biologicalmechanisms for dietary effects are reviewed. Findings support the hypothesisthat B nutriture is important for brain and psychological function inhumans." Healso showed: "Severe magnesium deficiency is frequentlyaccompanied by excessive electrical activity in the brain, includingseizure-like activity. This controlled, double-blind study investigated whethermarginal intakes of dietary magnesium, similar to those consumed by manyAmericans, would also result in increased brain electrical activity. Becauseprevious studies have shown that the mineral boron may affect biologicalresponse to magnesium, dietary intakes of boron were also examined. Compared towhen they ate more than 300 mg magnesium daily, postmenopausal women eatingapproximately 115 mg magnesium daily for six weeks showed increases in brainelectrical activity very similar to but not as extreme as those found withsevere magnesium deficiency. Some changes in brain electrical activity werealso found when these women ate less than 1 mg of boron daily, compared to whenthey ate more than 3 mg of boron daily. The effect of low dietary boron was todecrease the type of electrical activity associated with alertness. In very fewinstances did the amount of boron eaten affect the response to the amount ofmagnesium eaten. These findings are important to gaining a better understandingof the functional consequences of marginal as well as severe deficiencies ofmagnesium and boron in the diet." MaybeTracys observations were right on the money! Stay tuned! Iam also worried about toxic overloads of heavy minerals (lead, cadmium, mercury, etc.),and the criticalrole of other nutrients in mental health, which have only recently becomeof interest to physicians. The brain is a chemical factory that producesserotonin, dopamine, norepinephrine, and other organic brain chemicals 24 hoursa day. The only raw materials for their syntheses are nutrients, namely, aminoacids, cholesterol, essential fatty acids, vitamins and minerals. If the brainreceives improper amounts of these nutrient building blocks or receives toxicheavy metals, which take the place of essential nutrients (particularlyminerals) in the brain, we must expect serious problems with our organicneurotransmitters. For example, some depression patients have a genetic pyrroledisorder which renders them grossly depleted in vitamin B-6. A pyrrole is abasic chemical structure that is used in the formation of heme, which makesblood red. Pyrroles bind with B6 and then with zinc, thus depleting thesenutrients. These individuals cannot efficiently create serotonin (aneurotransmitter) since B-6 is an important factor in the last step of itssynthesis. Some people report 500 mg B6 to be needed daily to stabilize theirmood. Many of these persons appearto benefit from prescription drugs like Prozac, Paxil, Zoloft, or otherserotonin-enhancing medications. However, as with all non-nutritivemind-altering drugs, side effects occur and the true cause of the mentaldifficulties remains uncorrected. Similar - and more healthful - benefits canbe achieved by simply taking sufficient amounts of B-6 along with supportingnutrients such as magnesium, boron, taurine and essential fatty acids. If youwant to test your brain neurotransmitters, you can get them tested by using aneuroscience test kit supplied by local physicians. To find a local physician thattests neurotransmitters, contact NeuroScience,Inc. Succeed! Depression is not a psychosis! Foods That Contain 100 mg or Moreof Either Calcium or Magnesium per 100 Grams (3-1/2 oz) The following figure shows the amount of magnesium and calcium in foods whereinthe amount of either magnesium or calcium exceeds 100 milligrams (1/4 the RDAfor magnesium) per one hundred grams of that same food. A complete list ofhundreds of foods (fresh foods and processed foods by brand name) arranged bytheir magnesium content is in this USDAreport, which is a document that you should print out and tape to yourrefrigerator. Here is the USDAindex for all nutrients alphabetically and by weight. The followingfoods shown in bold and brown have more magnesiumthan calcium, while all other foods shown have more calcium than magnesium. > milligrams Magnesium per 100 grams food milligrams Calcium per 100 grams food Beverages & Mixes Cocoa powder 520 130 Chocolate drink 150 30 Milo 210 465 Ovaltine 0 270 Biscuits, Cakes, Cereals, Desserts Biscuit, chocolate 40 110 Biscuit, crispbread, rye 100 50 Biscuit, gingernut 25 130 Biscuit, semi-sweet 20 120 Bran, wheat 520 110 Buckwheat 230 114 Cake, sponge 10 140 Carob flour 10 350 Custard 10 140 Custard tart 20 110 Flour, soy (full fat) 240 210 Flour, soy (low fat) 290 240 Flour, wholemeal 140 40 Milk pudding (e.g.. sago) 10 130 Millet 162 10 Pancake 10 120 Pizza, cheese & tomato 20 240 Rye 115 38 Scone 20 620 Sponge pudding, steamed 10 210 Wheat bran 490 120 Wheat germ 336 72 Wheat grain 160 46 Yeast, brewers 231 210 Yeast, dried bakers 230 80 Egg & Cheese Dishes Cauliflower cheese 20 160 Cheese soufflé 20 230 Macaroni cheese 20 180 Quiche Lorraine 20 260 Fats & Oils None Fish & Other Seafood Crab, canned 30 120 Haddock, fried 30 110 Mussels, boiled 30 200 Oysters, raw 40 190 Prawns, boiled 40 150 Sardines, canned 40 460 Scallops, steamed 40 120 Fruits Avocado 106 5 Figs, dried 90 280 Lemon slices 10 110 Meat & Meat Products Tripe, stewed 20 150 Milk & Milk Products Buttermilk 10 120 Cheese, Camembert 20 380 Cheese, Cheddar 30 800 Cheese spread 30 510 Cream cheese 10 100 Cheese, Danish blue 20 580 Cheese, edam 30 740 Cheese, parmesan 50 1220 Cheese, processed 20 700 Cheese, Stilton 30 360 Cheese, Swiss 0 950 Ice cream 10 140 Ice cream, non-dairy 10 120 Milk, cows, condensed skim 40 380 Milk, cows condensed whole 10 280 Milk, cows dried skimmed 120 1020 Milk, cows dried whole 80 1020 Milk, cows evaporated, whole 30 280 Milk, cows flavored 0 110 Milk, cows fresh skimmed 10 130 Milk, cows fresh whole 10 120 Milk, goats 20 130 Milk shake, flavored 0 110 Yogurt, flavored 0 130 Yogurt, fruit low-fat 20 160 Yogurt, natural low-fat 20 180 Yogurt, plain 0 145 Nuts Almonds 260 250 Brazil 410 180 Cashews 267 38 Filberts 184 10 Pecans 142 73 Peanuts, raw in shells 130 40 Peanuts, roasted salted 180 60 Pistachio, shelled 0 130 Sesame seeds - hulled 0 110 Sunflower seeds 38 120 Walnuts 130 60 Sauces & Condiments Curry powder 0 645 Dulse (red seaweed) 220 300 Mustard powder 0 335 Olives, ripe 0 106 Oxo Cubes 60 180 Pepper 50 130 Worcestershire sauce 0 100 Soups None Sugars, Jams & Spreads Fish paste 30 280 Peanut butter 180 40 Treacle, black 140 500 Sweets Caramel 0 140 Carob bar 30 160 Chocolate square, milk 60 220 Fruit and honey bar 200 70 Molasses 258 684 Sesame bar 140 90 Toffee, mixed 30 100 Vegetables Alfalfa 230 900 Broccoli 24 103 Collard greens 57 250 Dandelion greens 36 190 Kale 10 250 Kelp (Warning! very high in glutamate) 760 1110 Onions, spring 10 140 Parsley, sprigs 50 330 Tofu 111 128 Turnip greens 10 250 Watercrest 10 150 No wonder we have trouble getting enough magnesium from our food! Calcium isfound in most of these foods in great excess over magnesium thus preventingmagnesium from being fully absorbed into the body. To us, calcium has become aneurotoxin. Have we lost some degree of control over the normally exquisitelyregulated calcium ion concentration in our brains? Can we recover if wecontinue to eat neurotoxins? I dont think so. Remember, the amount of magnesium and calcium is shown for 100 grams of thefood. Some of these foods we eat in small amounts, so the data is notparticularly meaningful. However, milk and cheese products, which we eat ingreat amounts, are loaded with calcium and harmful fats. We are not likely togain significant advantage from eating or drinking them in order to gainmagnesium. Want a pizza? How about a hamburger? I remember that my mother fedme a lot of peanut butter sandwiches when I was young. I grew to dislike thosesandwiches there were so many. But it looks like mom knew best after all. Shealso fed me lots of cocoa powder in water drinks. I hated them and demandedthat the cocoa powder be in milk (I thought she was being cheap). I still lovechocolate bars and drinks and I guess that is good. Chocolate contains manydrug-like compounds, some of which are very similar to anandamide, a substancein the brain whose name literally means "internal bliss." Anandamidebinds to and activates the cannabinoid receptors in the brain, mimicking theeffects of drugs such as marijuana. Almonds and peanuts I love, but I dontlike walnuts. Guess I need to develop a taste for them after all. I am surprised at how little magnesium and calcium there are in foods that Ithought were good for us, like eggs, soups, fish, fruit, meat and vegetables.Although meats and vegetables generally have more magnesium than calcium, onewould need to eat a lot of them to add up to a useful amount. I am surprisedthat pizzas (gobs of calcium) and hamburgers (not much of anything) are stilllegal. I am not surprised at the absence of magnesium and calcium in fats,beverages (alcoholic beverages were zero), sugars, sweets, sauces andcondiments. What do your eat? Does this table suggest your choice of foodsneeds to change to maintain a good mood? The official USDA Nutrient Database for Magnesium content of selected foods (30pages) is here.The USDA nutrient database for all foods and nutrients can be accessed here.Guess what characteristic the following foods have in common according to the USDA:Margarine, M&M MARS candy, STARBURST Fruit Chews, honey, radishes, cornsyrup, frosting, whipped cream, salad dressings, butter, cornstarch, beef brothsoup, chicken with rice soup, pepper sauce, candy, gumdrops, salt, alcoholicbeverages, Honey Nut CHEX cereals, carbonated beverages, and peanut, olive,sesame, sunflower, safflower vegetable oils. ANSWER: Zero mg magnesium per 100grams of the food. ZERO! Succeed! Depression is not a psychosis! Non-Dietary and Non-Stress Causesof Hypomagnesemia From the Hypomagnesemia web site,causes of low blood magnesium (hypomagnesemia) other than inadequate magnesiumand boronintake and stress are related to primarily to renal and gastrointestinallosses: Renal and gastrointestinal (GI) losses: Malabsorption of magnesium in the ileum results in hypomagnesemia. Situations of decreased absorption include malabsorption syndromes (e.g., celiac disease, sprue), radiation injury to the bowel, bowel resection, or small bowel bypass. Significant losses of magnesium resulting in hypomagnesemia may result from chronic diarrhea, laxative abuse, inflammatory bowel disease, or neoplasm. Renal losses from primary renal disorders or secondary causes (e.g., drugs, toxins such as mercury, hormones, osmotic load) may result in magnesium wasting and subsequent hypomagnesemia. Primary renal disorders cause hypomagnesemia by decreased tubular reabsorption of magnesium by the damaged kidneys. This condition occurs in the diuretic phase of acute tubular necrosis, post obstructive diuresis, and renal tubular acidosis. Drugs: Diuretics (e.g., thiazide, loop diuretics), cisplatin (causes dose-dependent kidney damage in 100% of patients receiving this drug), pentamidine, some antibiotics, fluoride poisoning, oral contraceptives. See larger list in this page here. Endocrine disorders: Primary aldosteronism decreases magnesium levels by increasing renal flow. Hypoparathyroidism and hyperthyroidism may cause renal wasting. Osmotic diuresis results in magnesium loss in the kidney: Diabetic patients, especially those with poor glucose control, develop hypomagnesemia from a glucose-induced osmotic diuresis. Alcoholics become hypomagnesemic partially by an osmotic diuresis from alcohol. Urinary losses have been reported to be 2-3 times control values. Miscellaneous: Extracellular volume expansion, as in cirrhosis or intravenous (IV) fluid administration, may decrease magnesium levels. Redistribution of magnesium into cells may cause lower magnesium levels. Insulin causes this effect. Excessive lactation may create a significant amount of magnesium loss. Hungry bone syndrome may lead to lower serum magnesium concentrations. Pregnant women have been found to be magnesium depleted, especially those women who experience pre term labor. Leaky Gut Syndrome. Always treat with probiotics. Antibiotics because they lead to the overgrowth of abnormal flora in the gastrointestinal tract (bacteria, parasites, candida, fungi) causing "Leaky Gut Syndrome". Treatment with probiotics and/or CoQ10 is often curative. Caffeine and other strong gut irritants. Foods and beverages contaminated by parasites like Giardia Lamblia, Cryptosporidium, Blastocystis hominis and others. Always treat with probiotics and/or CoQ10. Foods and beverages contaminated by bacteria like Helicobacter pylori, Klebsiella, citrobacter, Pseudomonas and others. Always treat with probiotics. Chemicals in fermented and processed food (dyes, preservatives, peroxidized fats). Enzyme deficiencies (e.g. celiac disease, lactase deficiency causing lactose intolerance.) NOTE: Scientists believe that lactose malabsorption may interfere with the availability of L-tryptophan and the synthesis of the neurotransmitter serotonin. NSAIDS (non-steroidal anti-inflammatory drugs) like ASA, ibuprofen, indomethacin, etc. Prescription corticosteroids (e.g. prednisone) and methotrexate. High refined carbohydrate diet (e.g. candy bars, cookies, cake, soft drinks, white bread). Mold and fungal mycotoxins in stored grains, fruit and refined carbohydrates. Toxic mold in the walls of buildings. Inadequate bile production. Inadequate garlic consumption. Inadequate iodine (iodide) intake. Moremedical important information on hypomagnesia symptoms and causes are here,and here on the FamilyPractice Notebook site. This google.com search for "magnesiumwasting may provide additional important information. Succeed! Depression is not a psychosis! Magnesium and Calcium Ions inSynaptic Function in Brain This figure from LTP LectureNotes from the Universityof California, San Diego - Department of Cognitive Science, one canclearly see that magnesium ions and calcium ions are involved in nerve cellelectrical conduction activity across brain cell synapses. Too much calcium ionand glutamate and not enough magnesium ion, particularly in the hippocampus,play a vital role in brain cell synaptic dysfunction leading to depression andother mood and behavioral disorders. The earliest indication that glutamate and many synthetic glutamate receptoragonists are toxic was obtained in the 1970s (Olney and Ho, 1970). However,most surprising was the finding that even endogenous glutamate may causeneurotoxicity via over-excitation under certain conditions - a situation called"excitotoxicity".Processes that increase the sensitivity of glutamate receptors or affectglutamate homeostasis often induce cell death usually connected with Calcium2+ion overload. Most of the better known neurotransmitter systems - dopamine, noradrenalin,serotonin (5HT), and acetylcholine in particular - have modulatory roles; andwhen defective require specific drugs, preferably supplemental naturalhormones, to restore their balance. They are produced by a few neurons locatedin specific clusters, and drugs affecting them often have specific effects.Receptors for these neurotransmitters tend to operate fairly slowly, takingmilliseconds or longer to communicate. Rather than directly changing thepotential of the neuron, they often trigger second-messenger responses. If youwant to test your brain neurotransmitters, you can get them tested by using aneuroscience test kit supplied by local physicians. To find a local physicianthat tests neurotransmitters, contact NeuroScience,Inc. On the other hand, most of the brains regular function operates quickly, andinvolves the excitatory and inhibitory amino acids. The excitatory amino acidneurotransmitters include glutamate (between 70 and 85 percent) and aspartate.The receptors for amino acids are generally calcium and magnesium ion channelsand to a lesser extent zinc. When the receptor is activated, these ions enteror exit the cell, which change its potential. Taurine, Gamma-aminobutyric (GABA) acid and glycine are major inhibitoryneurotransmitters in the central nervous system (CNS), predominantly active inthe spinal cord and brain stem. Taurine and glycine also acts as a modulator ofexcitatory amino acid transmission mediated by N-methyl-D-aspartate (NMDA)receptors. NMDA receptors are unique for several reasons. Unlike most neuronal receptors,they require two agonists (glutamate or aspartate, plus glycine) before thechannel opens. These two agonists bind to two different locations on the NMDAreceptor. After both agonists have bound to the channel, it opens enough forpotassium to enter. Normally, a magnesium ion is bound to a specific locationat the opening of the channel. The magnesium ion allows potassium to passthrough but prevents calcium. NMDA receptors are only activatedfollowing depolarization of the post synaptic membrane, which relieves theirvoltage-dependent blockade by Mg2+ ions. Once the cellbecomes activated enough, the cell potential rises enough that the magnesiumion is no longer stuck to the cell. Calcium can enter the cell through thefully open NMDA channel. Once inside, calcium sets into motion a series ofresponses, which enhance the strength of the synapse. Calcium helps cells do many things, including carry nerve signals. Neuronsnormally are very careful about the amount of calcium they allow in becausethey use minute changes in levels of internal calcium to interpret messagesfrom other neurons. Too much calcium inside cells leads to cell death.Over-stimulation of both non-NMDA and NMDA receptors with glutamate results ina large influx of calcium into the cell interior, particularly the neuronalmitochondria. Although normal levels are necessary for many cellular processes,if the intra neuronal mitochondrial concentration of calcium is excessive, suchcan result in a series of calcium-depended enzymes that are normallysuppressed, becoming activated. When these enzymes, like lipid peroxidase,nitric oxide synthetase, and xanthine oxidase, are activated, they cause theproduction of free radicals and nitric oxide, cytoskeletal breakdown, failureto generate ATP (the cells energy source), lipid peroxidation, and nucleicacid fragmentation, which leads to neuronal death. Similarly, in Wilsonsdisease (a serious copper accumulation disease), zinc given toeliminate copper accumulation (in the brain) results in elimination ofdepression found in Wilsons disease patients. NMDA receptors are involved in excitotoxicity (nerve cell death viaover-stimulation). The chemicals that agonize (activate) NMDA receptors canalso kill the very same nerve cells they are activating. Glutamic and asparticacid, are capable of doing damage if present in sufficient amounts. Thisexcitotoxicity is directly responsible for much of the damage attributed tovarious types of trauma and insult to the CNS from many diseases, and helpsexplain why magnesium glutamate and magnesium aspartate worsen depression(These compounds contain about 9 times the amount of these ligands thanmagnesium). Note "PRECAUTIONS" concerningusing magnesium glutamate and aspartate to treat depression. If you want to diginto neurotransmitter biochemicals further, see "Neurotransmitters",but you will not find mention of magnesium ions. If you want to test your brainneurotransmitters, you can get them tested by using a neuroscience test kitsupplied by local physicians. To find a local physician that testsneurotransmitters, contact NeuroScience,Inc. HaroldMurck writing in Nutritional-Neuroscience in 2002 pointed outthat there are several findings on the action of magnesium ions which supporttheir therapeutic potential in affective disorders. Examinations of thesleep-electroencephalogram (EEG) and of endocrine systems point to theinvolvement of the limbic-hypothalamus-pituitary-adrenocortical axis asmagnesium affects all elements of this system. Magnesium has the property tosuppress hippocampal kindling, to reduce the release of adrenocorticotrophichormone (ACTH) and to affect adrenocortical sensitivity to ACTH. The role ofmagnesium in the central nervous system could be mediated via theN-methyl-D-aspartate-antagonistic, gamma-aminobutyric acidA-agonistic or aangiotensin II-antagonistic property of this ion. A direct impact of magnesiumon the function of the transport protein p-glycoprotein at the level of theblood-brain barrier has also been demonstrated, possibly influencing the accessof corticosteroids to the brain. Furthermore, magnesium dampens thecalciumion-proteinkinase C related neuro transmission and stimulates theNa-K-ATPase. All these systems have been reported to be involved in thepathophysiology of depression. Despite the antagonism of lithium to magnesiumin some cell-based experimental systems, similarities exist on the functionallevel, i.e. with respect to kindling, sleep-EEG and endocrine effects. Carmanand Wyatt, writing in Biological Psychiatry as early as 1979showed that decreases in cerebrospinal fluid (CSF) calcium accompany moodelevation and motor activation in depressed patients undergoing treatment withECT, lithium, and total sleep deprivation. Similarly, decreases in CSF calciumoccur during acute psychotic agitation or mania. On the other hand, periodicrecurrences of such agitated states are accompanied at their onset by transientincreases in serum calcium and phosphorus. Several observations suggest thatsuch serum ion shifts may trigger the more enduring and opposite shifts in CSFcalcium and, in turn, the manic behavior. Progressive restriction of dietarycalcium was earlier reported to mitigate and finally abolish both rhythmicrises in serum calcium and periodic agitated episodes in one psychotic patient.Lithium, which decreases the efficiency of alimentary calcium absorption, mayfunction similarly. Conversely, a modest oral calcium lactate supplement(approximately one additional Recommended Daily Allowance of dietary calcium)seemed to slightly intensify agitation in six patients. Dihydrotachysterol(DHT), an analog of vitamin D, which more exactly mimics the increase in bothserum calcium and phosphorus, appeared in at least one periodically psychoticpatient to trigger and opposite shift in CSF calcium. Moreover, in eightpatients, manic symptomatology appeared de novo or grew significantly andsubstantially worse during 2 to 6 weeks of oral DHT administration. On theother hand, in 12 patients, subcutaneous injections of synthetic salmoncalcitonin (SCT) decreased serum calcium and phosphorus, increased CSF calcium,and decreased agitation while augmenting depressive symptomatology. SCT alsodecreased quantified motor activity, frequency and severity of periodicagitated episodes, serum CPK and prolactin, and nocturnal sleep, while DHT orcalcium lactate had opposite effects on the same parameters. Succeed! Depression is not a psychosis! Calcium Channel Blockers Calcium channel blockers, especiallymagnesium ions, alter influx of calcium from the extracellular fluid tothe cytosol of cells through calcium channels, which is important for therelease of neurotransmitters from presynaptic neurons. Thus magnesium ions actpresynaptically rather than by blocking receptors postsynaptically to preventover stimulation by calcium, and are therefore natures true calcium-channelblockers. In health,exquisite homeostatic regulation of serum calcium levels exists, andalterations from the norm in calcium serum levels are well known to causeserious mental illness. Free intracellular calcium-ion concentrations areelevated in platelets and lymphocytes of manic and bipolar depressed patientsbut not in control or unipolar depressed patients or in patients made euthymic(normal, neither elated nor depressed) by various medications orelectroconvulsive therapy (ECT). Some element of hyperexcitable as shown by Weston in 1921, oran imbalance in calcium/magnesium ratio (either induced by stress,improper diet, or calcium toxicity) in tissues are most likely necessary formagnesium supplementation to provide benefits observed in the treatment of thegeneral class of symptoms called "depression". I find interestingthat beneficial mechanisms of action of many dangerous, prescriptionpsychiatric drugs and ECT on manic and bipolar illness is restoration of propercalcium serum/magnesium balance, a property easily restored withover-the-counter magnesium taurate. Prescriptioncalcium channel-blockers often produce mental depression as a sideeffect in cardiac therapy, while magnesium used as a calcium channel blocker incardiology does not. I find it interesting that cardiology has embracedmagnesium to rescue patients, while psychiatry has not. The earliest substance to be reported having calcium-channel blocking effectswas magnesium ion. These findings were reported by Weston 80 years ago to ameliorateexcited psychotic states. See journal pages at: Weston, PG. Magnesium as asedative. American Journal of Psychiatry, 1921-22;1:637-8.Weston showed that 220 doses out of 250 doses of magnesium sulfate given to 50patients having various types of agitation, with half being patients havingagitated depression, caused patients to relax and sleep from four to six hours.This is about a 90% success rate. He noted that side effects from giving toomuch magnesium were quickly and easily reversed by giving calcium chloride.With such vital effects known for 80 years, it seems unlikely that psychiatrywill, without political force, in this century embrace magnesium in thetreatment of depression. Due to the strong Big Pharma lobby, deference will begiven to the known SSRIs and other patentable and highly profitableanti-depressant drugs, even though magnesium plays a much wider role in mentalhealth, particularly depression and other hyperexcitability states. Thepharmaceutical drug pusher lobby is simply too strong. Wouldnt federal andstate laws reading in part, "Treatment by physicians of disease with drugshaving any significant side effect without treating underlying malnutritionattributed to causing such disease, shall be considered malpractice"really change medicine for the better? Succeed! Depression is not a psychosis! Glutamate Toxicity Adverse effectssometimes occur in people who eat foods containing monosodium glutamate(sometimes called the Chinese restaurant syndrome). None of us should ever eatfoods or drugs containing substantial amounts of (monosodium) glutamate, or wemust greatly increase our magnesium intake at the same time to help detoxifyadditive glutamate. Although the side effects from aspartate is similar, it isnot as well considered [with the exceptionof aspartame (good link for FDA-Monsanto hanky-panky) and a linkbetween Gulf WarSyndrome and aspartame ingestion], perhaps because they are not used asextensively in foods. Glutamates are naturally found in cheese, milk, meat,peas, mushrooms, tomatoes, and soy sauce. Canned vegetables, caned soups andother processed foods often have additive glutamate (L-glutamic acid plus the toxic formD-glutamic acid) to enhance their flavor. Glutamates and aspartates arealso in some mineral dietary supplements (including magnesium), and are oftenreferred to as "amino acid chelates". Aspartame was shown in this 2005study to be a carcinogen, causing hymphomas, leukemias and brain cancerin rats. We must avoid these, because they are in so many foods that theiraccumulative effects can be quite severe. They show their toxic effects fromminutes to a day after ingestion making it difficult to determine acause-and-effect relationship unless one is aware. If you have some of thesesymptoms from time to time, check back in your memory and see if you can identifythe source(s) of glutamate. According to the Truth In Labeling Campaign,adverse effects of additive glutamate ingestion are dose dependent and mayinclude: > Cardiac Arrhythmia Atrial fibrillation Tachycardia Rapid heartbeat palpitations Slow heartbeat Angina Extreme rise or drop in blood pressure Circulatory Swelling Gastrointestinal Diarrhea Nausea/vomiting Stomach cramps Irritable bowel Swelling of hemorrhoids and/or anus area Rectal bleeding Bloating Muscular Flu-like achiness Joint pain Stiffness Neurological Depression Mood swings Rage reactions Migraine headache Dizziness Light-headedness Loss of balance Disorientation Mental confusion Anxiety Panic attacks Hyperactivity Behavioral problems in children Attention deficit disorders Lethargy Sleepiness Insomnia Numbness or paralysis Seizures Sciatica Slurred speech Chills and shakes Shuddering Visual Blurred vision Difficulty focusing Pressure around eyes Respiratory Asthma Shortness of breath Chest pain Tightness in the chest Runny nose Sneezing Urological / Genital Swelling of the prostate Swelling of the vagina Vaginal spotting Frequent urination Nocturia Skin Hives (internal and/or external) Rash Mouth lesions Temporary tightness or partial paralysis (numbness or tingling)of the skin Flushing Extreme dryness of the mouth Face swelling Tongue swelling Bags under eyes You will find "freeglutamate" in one form or another in almost all processed ormanufactured food as a flavor enhancer. Other names for glutamate include:monosodium glutamate (MSG), calcium caseinate, sodium caseinate, texturedprotein, natural flavoring, yeast food, autolyzed yeast, hydrolyzed protein,hydrolyzed vegetable protein, yeast extract, hydrolyzed yeast, natural chickenor turkey flavoring, other spices, and modified food starch. (NOTE: A list ofglutamate aliases suitable for taping to the refrigerator and using at thegrocery store to purchase non-glutamate containing foods is presented here.) Foodmanufacturers can use a reduced amount of a food product and some cheapglutamate while getting a big taste enhancement and saving a lot of money.Unfortunately, about 30 percent of the population will experience some adversereaction when they use this substance at the dosages available in foodproducts. Hereare disorders that are also caused, worsened or aggravated by excessiveglutamates from the MSGTruth.orgsite. MSG and Addiction,MSG and Alcoholism,MSG & Allergy,MSG and A.L.S., MSG and Alzheimers,MSG and Asthma, MSG and Atrial Fibrillation,MSG and Autism, MSG and Blindness, MSG and Celiac Sprue,MSG and Depression,MSG and Diabetes,MSG and Dizziness,MSG and Epilepsy,MSG and Fibromyalgia,MSG and Heat Stroke,MSG and High Blood Pressure,MSG and Hypoglycemia,MSG and Hypothyroidism,Irritable Bowel syndrome, MSG and Inflammation,MSG and Migraine,MSG and MS, MSG and Myopia, MSG and Obesity, MSG and Pituitary Tumors,MSG and Rage/Panic Disorder,MSG and Rosacea,MSG and Sulfite Sensitivity,MSG and Tinnitusand MSG and Sleeplessness. Supposedly, a natural glutamate antagonist is the structurally similar aminoacid L-theanine.I am not nearly as enthusiast about L-theanine as many, but I will complete therecord as follows. The similarity enables L-theanine (L-Glutamicacid-γ-monoethylamide) to physically block glutamate, thus preventing calciumion induced hyperexcitability. Although researchers arent positive howtheanine works yet, they theorize that theanine blocks the NMDA receptor whichis the doorway that glutamate uses to enter cells. Theanine is known toincrease GABA (Gamma-Amino-Butyric Acid), an important inhibitoryneurotransmitter. Because of the similar structure, theanine can also fit inthis doorway, blocking access to glutamate. But, although it can fit in thedoorway, theanine does not have the same effect on the cell as glutamate does.Rather than causing damage, theanine acts like a shield against damage.Theanine is the active ingredient in green tea. The Japanese have used enormousamounts of MSG for many years to improve taste of poor quality food, but theyoffset its toxic effects with green tea. In 1964, Japan approved theanines usein all food, except baby food. In Japan, you can buy over 50 different fooditems that contain theanine. Japanese soft drinks are spiked with the relaxant,and it has been put into chewing gum. The tranquilizing effects of theaninedefinitely are not imaginary. Theanine readily crosses the blood-brain barrierof humans and exerts subtle changes in biochemistry. An increase in brain alphawaves (resulting in an increase in wakeful relaxation) has been documented, andthe effect has been compared to getting a massage or taking a hot bath. And,unlike tranquilizing drugs (including kava-kava, valerian and St. Johns wort),it doesnt interfere with the ability to either think or exercise goodjudgement. It does not sedate, as demonstrated by no change in brain thetawaves upon administration. It does not help one doze or fall asleep, unless theperson is excited or hyper. By shutting down the "worry" mode,L-theanine increases concentration and focuses thought. This is the conceptbehind the Japanese tea ceremony which causes a person to focus on the moment. Dosage isreported to be 100 mg 1 to 4 times per day. Consider this: the risk ofmortality for Japanese women who practice tea ceremony is half of otherJapanese women. The Japanese are already the longest-lived people on earth.Interestingly, L-theanine is also reported to enhance the effects of cancerchemotherapy and reduce side effects by blocking glutamate. It may alsohelps block toxic effects of excess caffeine. Here is a search for "glutamate","toxicity" and "Japanese". Since we are so oftenexposed to excess free glutamate, we must learn more about dealing withoverdoses of glutamate. Is L-theanine helpful for depressives? If we arestressed, hyperexcited or too anxious, maybe. If not, it does absolutelynothing. It does not react with tranquilizers or other drugs, at least noadverse reactions have been reported. Is it expensive in the U.S.? Yes, itsretail price is over three times the price of gold, unless one purchases it inkilogram lots of pure powder, which is about one thousand dollars ($1 pergram). Is it worth it? I dont think so. Back to magnesium and taurine, supplementation has been used effectively as anantidote to nearly all, or all, of glutamates side effects. Magnesium does notreduce glutamate sensitivity or toxicity, although taurine does.This is another reason I have switched from magnesium glycinate to magnesiumtaurate. A 1995 reportfrom the Federation of American Societies for Experimental Biology (FASEB), anindependent body of scientists, reported to the Food and Drug Administrations(FDA) that temporary adverse reactions (headaches, perceived heart palpitationsand gastrointestinal discomfort) after consuming 3 grams or more of glutamateare likely. Parmesan cheese, a food with one of the highest levels of naturallyoccurring glutamate (andcalcium), contains about 1.3 grams of free glutamate per 100 grams.Ripe tomatoes are also high in glutamates. People with severe, poorlycontrolled asthma, in addition to being prone to the above symptoms, willsuffer worsening of asthmatic symptoms after consuming as little as 0.5 gramsMSG. Consequently, we have two or three major reasons to avoid parmesan cheese.Other foods with even greater amounts of glutamate and side effects caused bythem are listed here.A google.com search for "glutamates" is here. Remember my strong admonition to "NEVER USE MAGNESIUMGLUTAMATE"? Here is why. One gram of magnesium is attached to 15 gramsof glutamate to make 16 grams of chemical magnesiumglutamate (more properly termed Monomagnesium di-L-glutamatetetrahydrate). That amount of glutamate is over 5 times the level consideredproblematic by the FASEB, and clearly a severe health hazard to us. Yet the Congressallows glutamates in dietary supplements through the Dietary Supplement Healthand Education Act of 1994, apparently without regard to safety for us(depressives). Glutamates are generally defined as salts of glutamic acids, and have beenshown to be potent nerve toxins in laboratory cell cultures. Glutamates cancause a nerve to swell 90 seconds after contact. The mechanism for this is notentirely clear, but it is generally thought that exposure to glutamates causesa calcium influx in the nerve cell. Accordingto Dr. John Olney, a psychiatrist at Washington University in St.Louis,"Over twenty years ago glutamate was shown to cause brain damage to infantanimals. Since then, it has become increasingly evident that glutamate andclosely related substances are neurotoxins that can cause humanneurodegenerative diseases." As mentioned previously, MSG in combinationwith aspartame can be especially damaging. Not only may glutamates andaspartates cause degenerative nerve damage in adults, but there is growingevidence that the immature brain in children is more vulnerable than the brainof an adult since nerve myelination has not progressed very far. The glutamatesthat create this damage were also once added to baby food which incrediblydamages the still-forming brain in children. The Food and Drug Administrationagreed that one chemical, monosodium glutamate (MSG), should not be added to infantfoods. Food manufacturers removed MSG and added three different relatedexcitotoxins to replace the MSG. These chemicals are extremely dangerous to aforming brain, yet they arestill added to infant processed food products, because they promotegood taste and help insure that the infant will eat his processed food. Wait aminute! Is "processed food" an oxymoron? Whatare we to do? We are being flooded in excess glutamates and calcium from processedfoods, where they kill our brain cells. The blood-brain barrier is simplyunable to cope with the excesses of our "modern" American diet. Mark Leigton et al. point out that excess glutamateis more poisonous than cyanide to neurons, even though glutamateis absolutely required in low concentrations for most neuronal activities. Theglutamate-induced elevated calcium over activate a number of enzymes, includingprotein kinase C, calcium/cadmodulin-dependent protein kinase II,phospholipases, proteases, phosphatases, nitric oxide synthase, endonucleases,and ornithine decarboxylase. Some of these enzymes can also produce positivefeedback loops to accelerate the downward spiral toward neuronal death.Activation of phospholipase A, for example, generates platelet-activatingfactors and arachidonic acid and its metabolites. Platelet-activating factordirectly contributes to the excitotoxic cascade by increasing glutamaterelease. Arachidonic acid inhibits reuptake of glutamate from the synapticspace, leading to further activation of glutamate receptors and morearachidonic acid formation. Increased arachidonic acid levels form oxygen freeradicals, which activate phospholipase A, leading to more arachidonic acidformation. These enzymes and the generated feedback loops rapidly lead toneuronal self-digestion by protein breakdown, free radical formation, and lipidperoxidation. Tomy way of thinking, this is like saying that excess (spilled) gasoline ishazardous to a car. One match and "ka-boom!" the whole thing is gone.Long ago the Environmental protection Agency prohibited spilling gasolineduring refueling cars at service stations. In some states (California), theywont even let gasoline fumes into the air during refueling. Yet the Food andDrug Administration is prohibited by law (DSHEA) from wipingup excess neurotoxins more dangerous than cyanide. In fact, glutamates areencouraged and are found (in one form or another using aliases) in mostprocessed foods. You will be fascinated reviewing the neurological graphics andastonishing glutamate toxicity material by Leighton et al. in their article "PictorialReview of Glutamate Excitotoxicity: Fundamental Concepts for Neuroimaging". Even though there has been massive public uproar, lawsuits, controversy, andstrong anecdotal evidence of great harm caused by chemical addition ofglutamates in our foods and drugs, the FDAconsiders it safe and effective for most people exceptasthmatics (a known magnesium deficiency disorder). Although foodproducts containing additive "glutamate" are now required to belabeled, the labeling requirements can be easily avoided by using one of theabove related compounds. No matter what the FDA says, glutamates are vitalcomponents of neurological function and tossing in extra glutamate in abnormalamounts really messes up our brains! PERIOD!!! Can you imagine what wouldhappen if a mechanic tossed in a bucket full of bolts and nuts into a machinehaving moving parts? HA! No mechanic would be fool enough to do that! So whatis the FDAs problem (beyond the Congress)? It is spelled: I-n b-e-d w-i-t-h t-h-e p-h-a-r-m-a-c-u-t-i-c-a-l i-n-d-u-s-t-r-y,who just happen to make money selling drugs to treat these symptoms. Ethics?HA! Processed food quality and purity? HA! They gotcha sucker! Corporations make much moremoney selling inferior foods processed with glutamates than without it. If afood product is not in natures wrapper, it has been processed by corporations, and it maycontain glutamates or closely related chemicals. Wonder why you feel bad sooften? "Take two magnesiums (aspirins) and call me in themorning". Succeed! Depression is not a psychosis! High Quality Sleep If you have suffered depression, anxiety or any of the magnesium deficiencymental health disorders mentioned here, you most likely have or have hadserious, chronic sleep problems. Very often well-meaning physicians prescribebenzodiazepines (hypnotics) such as alprazolam (Xanax), clonazepam (Klonopin),diazepam (Valium) and lorazepam (Ativan) for anxiety and insomnia. To manypeople they are magic! They do promote sleep and they do relieve anxiety. Butis this a healthy way to achieve these goals? With long-term (more than twoweeks) high-dose use of benzodiazepines, there is an apparent decrease in theefficacy of GABA-A receptors, presumably a mechanism of tolerance. Whenhigh-dose benzodiazepines are abruptly discontinued, this "down-regulated"state of inhibitory transmission is unmasked, leading to characteristicwithdrawal symptoms such as potentially serious anxiety, insomnia, autonomichyperactivity and life-threatening seizures. In other words, you are really, reallyhooked! Withdrawal efforts must be excruciatingly slow, perhaps requiringmonths to carefully reduce dosage to the tiniest possible dosage, and up to twoyears to become completely recovered from all side effects of these drugs oncethey have been stopped. I relied on Klonopin for sleep for 15 years before Irealized how harmful this drug could be for me. I loved going to sleep withKlonopin. Each time I tried to taper off, I was overwhelmed by side effects.For me the scariest were high anxiety, serious insomnia and many transientsymptoms for which I could not find a cause - all because I asked a physiciannearly 20 years ago for help going to sleep? If you have taken any of thesedrugs, you are most likely experiencing one or more of hundreds of potentialside effects, and are not nearly as sick as you think! Please take the time toprint and carefully review the huge list of side effects from use of thesedrugs at the Benzodiazepine.orgsite. I had the list here, but it was many pages long and I had to resort tolinking the site. How can anyone defend drugs that will replace simple insomniawith much worse long-term problems? To many people these drugs have becomedrugs from hell. If necessary during the withdrawal process, you probably canuse these drugs with magnesium, but the effects of both the drugs and magnesiumin inducing sleep should be considered. MOST IMPORTANT: You must seek theadvice of a physician or pharmacist for specific instructions on safewithdrawal from these drugs. Good luck in finding a physician that will helpyou withdraw. By the way, your physician will probably offer you a drug totreat each and every one of your benzodiazepine side-effects, or you can takemagnesium and get well. A more complete list of benzodiazepine drugs include:Alprazolam (Xanax), Bromazepam (Lexotan, Lexomil), Chlordiazepoxide (Librium),Clobazam (Frisium), Clonazepam (Klonopin, Rivotril), Clorazepate, Diazepam(Valium), Estazolam (ProSom), Flunitrazepam (Rohypnol), Flurazepam (Dalmane),Halazepam (Paxipam), Ketazolam (Anxon), Loprazolam (Dormonoct), Lorazepam(Ativan), Lormetazepam (Noctamid), Medazepam (Nobrium), Nitrazepam (Mogadon),Oxazepam (Serax, Serenid, Serepax), Prazepam (Centrax), Quazepam (Doral),Temazepam (Restoril, Normison, Euhypnos), Triazolam (Halcion).Non-benzodiazepines which may have similar side effects include: Zaleplon(Sonata), Zolpidem (Ambien, Stilnoct), Zopiclone (Zimovane, Imovane). Howdid I go off of Klonopin, and what did I experience? Briefly, after two yearsof hell, life is beginning to become normal. The following is an e-mail answerto a man announcing that he was going off Klonopin after being on it for nineyears. He wanted to know how I went off Klonopin and what were my experiences. > Dear Terry, Congratulations on your decision!!!!! My condolences too. You and I have had our brains rewired to depend upon Klonopin for many things, sleep being one of them. Your best future depends on withdrawal I believe. However, this will be an extremely slow decent through hell, but there is a silver lining. The easy part is slowly tapering from the big doses to the little doses. When you finally get down to one 0.5 mg pill, the trouble starts. You should further taper to a half pill and stay there for a few weeks. Then you should taper to a 1/4 pill and stay there for a few weeks. Then you should taper to 1/8 pill and stay there for a few weeks. Finally, you will decide to stop. Then, hell breaks loose and you may think you are ill to very ill with one or more (usually multiple) of the side effects mentioned on the Benzodiazepine.org site. You will be tempted to see a physician for one or more health issues that are clearly identifiable as Klonopin withdrawal symptoms. You will not trust your health. You will think that sleep is impossible. You will be certain that there is something wrong with you when you can no longer sleep. Hopefully, you will use about 400 to 500 mg magnesium as taurate at bedtime as a sedative. You will probably wake up after 4 to 5 hours totally relaxed and rested and ready to get up. You can get up and putter around the house or try to do something useful. For me, those were the hours that I used to write my web page. At a recent conference on magnesium, one of the speakers said that he thought that the reason for the early awakening was due to the ready detoxification of calcium by magnesium. If we dont get enough magnesium, then we require more sleep to detoxify excess calcium. Complete trust for your health will not occur for at least a year and perhaps two. That means for that year or two, you will be rather uncomfortable and will have many weird symptoms. IT IS JUST KLONOPIN SAYING, "MISS ME?" Tell yourself, "I am in withdrawal" and relax. Tell yourself again, "I am in withdrawal" and relax. Repeat this one hundred times. Anxiety about your health may be more than you can tolerate, and you will probably be very tempted to go to a doctor for more drugs. Please tell yourself that there is no nutritional requirement for drugs, but there is for magnesium. I could go on, but you get my drift. I will never go to a doctor again unless I am on a stretcher or need some kind of shot, and I get my flu shots at Wal-Mart! Hope that helps. George In depression,high quality sleep is mandatory for recovery, but is often very difficult toachieve without magnesium and taurine repletion and a low glycemic diet.Remember that both stress and a high glycemic diet dramatically lowerintracellular magnesium and must be controlled. Had Westons discovery of thesedative value of magnesium been fully utilized over the last 80 years, manyproblems due to inadequate sleep (in depression or otherwise), could have beenlargely avoided. Clearly, 400 - 500 mg of ionizable magnesium at bedtimeinduces a natural, pleasant sleep unequaled in the human experience. On theother hand, lack of sleep is another cause of magnesium deficiency; probablydue to the lowered amounts of growth hormone secretion, which occurs as resultof sleep deprivation. Growth hormone is responsible for creating a substanceknown as insulin growth factor (IGF-1). IGF-1 has been found to have many usesin the body, but is best known for tissue repair, which occurs primarily duringsleep. Lack of sleep is often found in people with fibromyalgia,which is responsive to magnesium repletion. Magnesium ions regulate many nervereceptors, such as NMDA or 5-HT3. When inadequately regulated due to magnesiumdeficiency, those receptors cause fibromyalgia pain and increase sleepdeprivation, further worsening magnesium deficiency. Worse, Tanabeand others have shown a link between sudden cardiac death from chronic fatigue(lack of sleep) and magnesium depletion. They hypothesized that coronaryarterial spasm and thrombus formation occur during chronic fatigue. They foundin a small trial that chronic sleep deprivation leads to a cellular magnesiumdeficiency and an increase in the thromboxane B2 level, thus promoting coronaryarterial spasm and thrombus formation. Toomuch carbohydrate in the diet will cause insomnia, partly because it interfereswith magnesium. Sugar prevents magnesium from staying in cells and adversely alters calciumand magnesium intracellular balances, worsening depression too. Excesssugar, less than one might imagine, results in severe urinary losses ofmagnesium. Sometimes people on magnesium will awaken early, too early, perhaps2:30 to 4:00AM, and can not get back to sleep. This is rarely (if ever) from"excessive" magnesium, and is much more likely to be fromhypoglycemia induced by hyperinsulinemia. This is especially suspect if thepulse rate is higher than normal. Supplements of chromium and vanadiumat the time of insomnia with higher than normal pulse rate should bring downthe pulse rate and allow sleep to resume. Earlyawakening (after about 3 to 4 hours sleep) without a high pulse rate is type IIinsomnia. It might be caused by calcium deficiency, but the researchers at arecent magnesium conference suggested that it was due to the effect ofmagnesium detoxifying calcium. They thought that too much calcium makes ussleep longer simply to detoxify it. Type II insomnia might mean you have doneyour job of depleting excess calcium by following a low calcium or a calciumreduction diet as discussed. Excess, toxic, amounts of calcium have beenremoved from the blood. This effect will usually require about a year ofpurposeful trying to deplete calcium. Consequently, if you are a recent convertto low calcium intake, you may not notice this effect. Many people find thatadding small amounts of calcium, preferably as a small serving (3 to 6 FL OZ)of ice cream, to their diet shortly before bedtime will prevent calcium"deficiency" insomnia that same night. On the other hand, difficultyin getting to sleep is vastly more common and is called type I insomnia, whichis caused by magnesium deficiency. What do sleeping aids like the benzosactually do? They mask magnesium deficiency. For that reason alone, they shouldnot be used. Ifyour brain glutamate levels are high, and they often are in depression, theglutamate causes hyperexcitability and greatly reduces our ability to rest andsleep. Sleep is interrupted and short, perhaps no longer than a few hours at atime. I thought that I had my glutamate levels managed by taking magnesium andspecifically magnesium taurate. Taurine, an inhibitory neurotransmitter,counters the excitatory neurotoxin effects of glutamate. But how much taurineis needed? I dont know in all cases, but it took two grams of taurine witheach meal and two grams at bedtime and at 4 a.m. for me to get a full nightssleep and to feel completely rested. In my case, I have become so old that I nolonger make enough taurine for me to be able to keep my neurotransmitters inbalance. Actually, I am not that old, but when taurine levels fall (perhapsfrom liver damage), one feels very old and lacking in both energy and theability to relax and sleep. Low taurine is rampant world-wide and is a maincause of the extremely successful "energy" drinks like Red Bull,which contains one gram taurine per can. Too bad Red Bull is loaded withcaffeine. Forget Red bull at bedtime!!! I believe alcohol consumption is themain cause of liver damage resulting in loss of taurine production ability. Ifyou want to test your brain neurotransmitters, you can get them tested by usinga neuroscience test kit supplied by local physicians. To find a local physicianthat tests neurotransmitters, contact NeuroScience,Inc. Anotherpossibility for early arising is spiking cortisol at these early hours.Normally cortisol increases at about 8:00 a.m. to help us cope with our day andfalls in the evening and remains low during sleep. However, my cortisol levelsare at their highest between 3 a.m. and 8 a.m., which causes me to awaken fullof energy and with a razor sharp mind. It is during these hours that most ofthe work on this page occurs. Perhaps I need to live in Europe to take advantageof the time difference. Maybe my spiking cortisol levels would work our betterfor me. You can find out about your cortisol levels at various times of the dayusing the Salivatestkit. Since my cortisol levels are low during the day, I take naps. Mostof us do things daily that adversely affect our ability to sleep, that whenlooked at in context, make little sense. For example, we take stimulants in themorning to get us going and sedatives in the evening to help us relax andsleep. We love our sweets too and we find them everywhere, making avoiding ahigh glycemic index diet difficult. Some of us also take decongestants (AfrinNasal Spray, Sine-Aid, Sudafed) or appetite suppressants such as Acutrim andDexatrim which are strong stimulant drugs, which should be avoided byinsomniacs. Our economy promotes the idea of more is better and less is counterto supporting our "way of life". Well, perhaps that is true, but atwhat cost to us as individuals? Can we be turned on in the morning and off atbedtime like a machine? A machine? Do we really want to be machines? Where didwe get the idea that we have to perform as perfectly as a well tuned Ferrari,go like a banshee each day and sleep like a baby each night? Somehow we havelearned this concept while growing up, most likely from our parents, teachersand peers. Now we are in a pickle, depressed and even burnt out but unable tosleep. Why? I think many of us turn on in the morning and off at night ondemand - using drugs. Drugs? You say, "I dont use cocaine or speed to getme going in the morning!" No? What do you use to get going in the morning?Caffeine from coffee, tea or colas? Do you have to have your coffee to getgoing in the morning? How about an afternoon cup of tea or a cola? How aboutsome lovely chocolates in the evening? How about 800 nicotine hits per day?These products sound totally benign (with the exception of smoking), but theyeach share one thing in common with the most dangerous drug in the world -crystal methamphetamine. They are all stimulants. All of us react to stimulantsand sedatives differently, and many people can turn on and off successfullyusing drugs. But do we all pay a price eventually? Usually. You paid the priceor you would not be reading this. Every morning you get up have a cup of coffeeand never consider that caffeine could be building up in your body and keepingyou from sleeping at night. Me? I have never drank a cup of coffee in my lifeand I still have trouble sleeping. I am so extremely sensitive to caffeine thatone cup of tea or a single chocolate bar contain enough caffeine to keep meawake at night - for several nights! Are you hypersensitive to caffeine too butrefuse to admit it? Most of us will not admit that uppers like caffeine keep usfrom sleeping. It is part of our lives! We depend upon our cup of coffee, andwill not stop using this drug. DRUG? Caffeine? Yes. It is an upper just likecrystal meth. Stimulants: caffeine and nicotine, cocaine (including freebase,rock, and crack), amphetamines, meth, ("crank, speed"), diet pillsand decongestants all have big payoffs, such as energy, productivity,confidence, coping with depression and stress. Users often appear successfuland well adjusted. But we all have a stress reaction to them. All these drugsimitate or stimulate the production of norepinephrine or adrenalin, creating a"fight or flight" response, in addition to the pleasure response.Doesnt this sound familiar? What have I been preaching about stress as theultimate cause of depression? Here we are again, depressed and feeding thatdepression with things that keep us from sleeping! Are we weird or not! Yes, wehave become very weird in our "behavior". Did you know that yourdecongestant was keeping you from sleeping? Better take Nyquil! How aboutcalcium plus aspirin? How about: Ephedra? Aspirin Plus Caffeine (APC)?Excedrin? Why do you think they make Excedrin PM? Whatabout sleeping pills? Are they OK to use? The answer is usually no, not for us.Research proves over and over again that sleeping pills are actually the worsttreatment for chronic insomnia. The reason is that sleeping pills merely coverup the underlying cause of the insomnia. After a while, people develop atolerance to or dependency on the sleeping pill and never really treat thereason for the insomnia in the first place. To truly cure our insomnia, we needto seek medical help to receive a diagnosis and treatment for the root cause ofthe insomnia. Guess what your doctor will find as the root cause of yourinsomnia? Depression. Back to magnesium. Use of mild sedatives, sleeping pillsor antihistamines, such as Benadryl®, to induce sleep without magnesium intreating depression can result in much worse problems than they solve. On theother hand when used as part of a magnesium repletion program, they can workmiracles. Want me to recommend one? You might try low dose (25 mg) Benadryl®.However, we must detoxify ourselves of stimulant drugs such as caffeine andnicotine first, which is something most people will not do. However, if you areinterested in detoxifying from stimulants and are want to learn more, start here.Withdrawal from stimulants usually increases depression for a while, and a bitof 5-HTP will help as discussed in the next paragraph and elsewhere in thisessay. Didyou know that taking a morning or afternoon nap can keep you from sleeping atnight? Researchers have found that taking a nap lasting 20 minutes or longerwill reset the biological clock, making nighttime sleep difficult andinterrupted. Also, flying from one time zone to another, particularly multipletime zones, will also affect nighttime sleep patterns, because your biologicalclock is set for your origin time zone - not the destination time zone. Thesechanges in your biological clock can be reset with melatonin. However, for thedepressive, be careful with melatonin,the biochemical that establishes our natural sleep rhythm. Examine melatonindietary supplement labels carefully, and quality melatonin products will warn:"Not for use by depressives". Why? Melatonin is involved in the sleepprocess, why wouldnt it be helpful? Melatonin is a hormone (N-acetyl-5methoxytryptamine) produced especially at night in the pineal gland. Itssecretion is stimulated by the dark and inhibited by light. Tryptophan isconverted to serotonin and finally converted to melatonin. During sleepserotonin is converted to melatonin and during wakefulness melatonin isconverted to serotonin. However, the person with depression may not be able toconvert melatonin into serotonin effectively and melatonin may build upworsening depression and causing the person to oversleep. What to do?Supplement with both melatonin and 5-HTP, theimmediate precursor to serotonin (vital to sleep). How much? Try using 50-mg5-HTP, and 3-mg melatonin. This may help correct the problem for depressives ina wonderful way, and allow us to benefit from melatonin as well as benefit fromthe sleep enhancing effect of 5-HTP supplementation. How about a big glass ofmilk for sleep induction? HA! Not for depressives. However, calcium is involvedwith sleep maintenance as previously mentioned, but we usually get enough fromour diets even if we work to eliminate toxic amounts of it as discussed here. Aswe age we produce less and less melatonin. Melatonin levels have been proposedto be a direct indicator of chronological age in forensics because melatoninproduction declines nearly linearly with age. Low night-time melatonin productionis likely the main cause of insomnia in older people and particularly in theelderly. Normally, melatonin concentration is 6 to 12 times higher at nightthan during the day. Replenishing night-time melatonin to youthful levelssometimes results in restoration of youthful sleep patterns. Melatoninproduction is also inversely associated with nocturia (total urinary output andurinary frequency at night). Yes, total urinary production is greatly reduced,suggesting melatonin levels control urinary production, which appears relatedto melatonins role in lowering night-time blood pressure. Many older men thinkthat they have prostate problems because they frequently are awakened by astrong need to urinate, often 3 to 5 times a night. This is another aspect ofinsomnia and depression that appears poorly treated in medicine. Melatoninnearly always cures the supposed "prostate problem", because itwasnt a prostrate problem at all. Melatonin is equally effective in women. Thetime of day that melatonin is taken to prevent insomnia and nocturia isimportant, and must be determined by each person due to individuality ofmelatonin metabolism. Taking melatonin at about 10 PM is a good starting pointin eliminating nocturia and its resulting insomnia. On the other hand, ifmelatonin is taken in the morning, night-time insomnia will likely result,because it will change the bodys clock. If insomnia persists and one takes an"extra" tablet in the early hours of the morning, sleepiness mayoccur during the day for the same reason. Some researchers report that severalweeks of treatment with melatonin may be required before insomnia and nocturiaabate, while others report two treatments is sufficient. Rarely, it works onthe first night, perhaps because correct dosage or timing has yet to beestablished, or because too much liquid is consumed several hours beforebedtime (in the case of nocturia). If melatonin terminates insomnia andnocturia, supplementation may be needed for years. As side notes, people thatwork or around electromagnetic fields (especially microwave) are often low inmelatonin, presumably by action of the electromagnetic field on melatoninmetabolism. Cancer treatment and prevention using melatonin has been discussed.According to Dr.Joseph Mercola as sleep quality and quantity declined in aging, levelsof the adrenal hormone cortisol increase, while levels of Growth Hormone (GH)declined. After the age of 25, men experience a decline in deep sleep thataccompanied by a drop in GH production. GH deficiency is related to reducedmuscle mass and strength, increased fat tissue, weakened immunity to infection,and other health declines. In later years, a new sleep pattern emerges, inwhich men get less sleep overall and levels of cortisol go up. Cortisol levelsincrease especially in the early morning hours from 2 a.m. to 4 a.m, whichusually wakens the person due to its stimulating effects. Strangely, cortisollevels at other times of the day may be lower than normal. Elevated cortisolmay underlie a host of mental and metabolic problems, including memory loss andinsulin resistance -- a precursor to diabetes. One of the best discussionsconcerning the severity of high cortisol as it relates to stress and adrenalfunction is found on the Dr. Lam siteat his adrenalfatigue page. He shows that when our body is stressed in a prolonged,unnatural way (may be a standard way in our Western high pressure work andsocial environment), our cortisol level rises in an environment where theadrenal negative feedback system is dampened. While this is happening, our DHEAlevel continues to drop (but high DHEA can be maintained by high magnesiumintake according to Dr. Noman Shealy and my own personal observations). Theresult is a high cortisol to DHEA ratio and: Reduced insulin sensitivity, reduced glucose utilization and increased blood sugar, which lead to diabetes. Reduced secretory IgA (the main cellular defense factor), natural killer (NK) cell and T-lymphocyte activity. This leads to increase chances of getting infections such as Herpes, yeast overgrowth, and viral infections. Increased loss in bone mass as calcium absorption is blocked and demineralization of bone occurs, thus leading to osteoporosis. Increased fat accumulation around the waist and protein breakdown, thus leading to muscle wasting and an inability to reduce weight. Increased water and salt retention, leading to high blood pressure. Estrogen dominance, leading to PMS, uterine fibroids, and breast cancer. Conseqently,maintaining a high magnesium status can mute most of the effects of highcortisol at least in part by raising DHEA. Succeed! Depression is not a psychosis! There are many tried and true methods of getting to sleep that do not involveadjusting biochemistry. These techniques involve stress and pain avoidance.Obviously your bedroom should be as comfortable as possible. After all,sleeping is required to rejuvenate your entire being. A painful night from anuncomfortable bed is not conducive to sleep. Some people are so calcified bycalcium-abuse that their joints and back hurt from laying down, which likelyapplies to you. As your magnesium/calcium balance improves over the first yearof magnesium replenishment and calcium depletion, you will likely notice thatpain associated with sleep disappear. In the meantime, good pillows, sheets anda firm, comfortable mattress are necessary. An "egg crate" foam pad(as seen on right) is often the difference between quality sleep and poor or nosleep. They are available at any sleep or bedding store and make poormattresses work like the best mattress ever made. However, the "best"mattress is not a stuffed mattress at all, but is an air mattress. These twoitems, "egg crate" foam pads and air mattresses are the ultimate insleep equipment, and they are very inexpensive. Make bedtime as routine aspossible. Do not oversleep in the morning (the melatonin problem). Make sureyour room is quiet, dark (too much light = melatonin problem) and has acomfortable temperature that is neither too hot nor too cold. An electricmattress pad is often preferable over an electric blanket, because heat comesup from below. Listen to poetry or soft music. Your bedroom should only be usedfor sleep and sex. Sex aids sleep. Dont watch television, work, read or talkon the phone. Bathing your insomnia away with an Epsom salts bathoften is very helpful. Finally, use any appropriate stress relief technique listed here. Peoplesometimes find that when they go off their drugs and onto magnesium that theywake up after about 5 hours (often about 3 to 4AM) and cant get back to sleep.If sugars have been kept low, calories restricted generally, adequate chromiumand vanadium ingested, nocturia controlled, melatonin taken, stress relieved,comfortable sleeping arrangements provided, then is all than can be done? Whyno sleep? You are no longer under so much stress that you need your previousamount of sleep. Get up and do something productive or enjoyable, read a book, listento music or find a second job! Enjoy your time awake, because sleep is too muchlike death to enjoy sleeping more than necessary. With magnesium repletion, youdont need as much sleep. Or, you can have a nice bowl of ice cream beforebedtime and sleep a few more hours than normal. Alternatively, you can takeanother 400 mg of magnesium and hope you make it to work on time withoutdiarrhea. According to Dr. Joseph Mercola, MD, "the need for sleepis akin to the need for food, in that getting less than people want may bebetter for them." In other words, with magnesium repletion, eventhough you may not get as much sleep as you want, you will be healthier. Dyingto get more sleep? The operative word here is "dying". Did you knowthat improper sleep position can cause death? In the infant, SuddenInfant Death Syndrome (SIDS) remains a leading cause of death duringthe first year, and is now suspected as being a severe magnesium deficiencywhile sleeping on the stomach. Similarly, adults with magnesium deficiency whosleep on their stomachs risk death too. Why? An infant or an adult sleepingface-down in the prone position could be jeopardized if he lacked the musclestrength to shift his position or turn his head to rescue himself from alife-threatening situation. Muscle strength can be seriously impaired in themagnesium deficient subject, while magnesium rapidly reverses muscle weakness.Obesity directly increases risk of death while sleeping on stomach. Think aboutit for a moment. When you lay on your stomach and you try to breath in, youslightly lift your entire upper body using your diaphragm muscle! Is that agood idea for waking up in the morning? NO! Be careful while sleeping on yourstomach. On the other hand, sleeping on your back only requires your diaphragmto lift your rib cage. Sleeping on your side requires no lifting of any bodypart, and is the safest position for sleeping. However, you can ruin yourshoulder joint by sleeping on your side while using your arm as a pillow. Whenthe arm is extended above your head while sleeping on your side, tearing and inflammationcan occur in the shoulder joint resulting in a condition called "frozenshoulder" or adhesive capsulitis. This is a rare but painfultendon condition that lasts for about a year, with several phases. The pain isbest likened to momentary scorpion stings, coupled with a "jointpopping" sensation that is both palpable and audible. I can assure youfrom personal experience, that frozen shoulder will keep you a wake at night.No sleep is possible when scorpions sting you every time you shift positions.This will definitely keep your partner awake too! Treatments are varied, andapparently depot cortisone shots directly into the shoulder produce the mostrapid relief. I, on the other hand, will not allow physicians to inject me withcortisone, and I found that a strong solution of Epsom Salts (magnesiumsulfate), water and DMSO applied topically to my shoulder each several hoursseems to work as well as non steroidal anti-inflammatory agents, but withoutthe side effects. Fibromyalgia, Chronic FatigueSyndrome and Magnesium Fibromyalgia, (severe muscle cramps or pain in leg, foot, neck, chest, back,soft tissue) and chronic fatigue syndrome (CFS) appear nearly always symptomsof moderate magnesium deficiency coupled with excess extracellular calciumaccumulation (but low intracellular calcium) and possibly low potassium. Forexample, Shealy, et al. showed in 1992 that 80 percent of more than 200patients with depression and/or chronic pain had magnesium serum levels belownormal here. Magnesium malate has ahistory of use in treating fibromyalgia. Many articles concern lowmagnesium levels in chronic fatigue syndrome and lowmagnesium in fibromyalgia. Also, there is much interest in potassiumproblems in CFS. Although I am quite certain that fibromyalgia is primarilya low magnesium problem, I now believe that CFS is a low magnesium andlow potassium problem. This seems to be a novel approach to treating CFS, butit may have much more merit than anyone could have predicted as few as 5 yearsago. See the discussion in this page concerning foods and salts that can beused to increase potassium here, and do asearch generally in this page for "potassium" to learn about itshazards and benefits. Potassium is the most prevalent metal inside cells atabout 70% of the mineral content of cells, and plays vital life- andhealth-sustaining roles. See this page fora comprehensive discussion of treatments and causes of CFS. As previouslymentioned, magnesium regulates many nerve receptors, such as NMDA or 5-HT3.When inadequately regulated due to magnesium deficiency, those receptors causefibromyalgia pain and increase sleep deprivation, further worsening magnesiumdeficiency. Fibromyalgia and chronic fatigue syndrome are often not diagnosedby internists, rather they conduct multiple expensive tests to rule out otherpossibilities. These painful symptoms are always predictive of major health problemsin the future including cardiac trouble and depression if not treated withionizable magnesium at about 200 mg three to four times a day. However,menstrual cramps are symptoms of zinc deficiency, notmagnesium deficiency. Read more in this essay about how calcium toxicity andmagnesium deficiency cause fibromyalgia here, and a bitabout the problem of sleep in fibromyalgia here.Doesnt it seem more reasonable to you, the patient, to try somethingnutritional before spending a fortune on expensive tests? You dont believe me?How about believing a MITresearcher and his extensive research? If you wait for your doctor tomake this diagnosis, I hope you have plenty of money or really good insurance.On the other hand, see what one of the best CFS physicians in the world, Dr.Sarah Myhill in Great Britain does for fatigue here. Succeed! Depression is not a psychosis! Red Eyes, Dry Mouth, Dry Eyes Scleritis(sometimes painful, but always severe redness in the white part of eye)is a disease usually of unknown origin, but has been documented in arthritis,and several infectious diseases. Scleritis can be recurring, and in my case,the red eye syndrome lasted for about a week and reoccurred each 4 to 6 weeks.No drug was effective in treating this eye condition, but it did respondslightly to magnesium sulfate eye drops. On the other hand, taurine is known tobe vital for eye function and much information is available on this matter,particularly in macular degeneration. However, no one has documented the effectof dietary or topical taurine on scleritis. Severe scleritis is an importanteye disease because it has been found to occur in people in the last 5 years oftheir life. Since I first developed scleritis in my left eye in 1999, by thefall of 2003, I was wondering how that would work out! Upon switching frommagnesium glycinate to magnesium taurate last summer, my only incident ofscleritis was much milder. I reasoned that the only real change that I had madewas to greatly increase my taurine intake. Being somewhat a curious George, Imade a saturated solution of taurine and dropped a few drops into my eye atbedtime. The next morning the redness was totally absent. Following up ontopical taurine by using dietary supplements of taurine and the eye-drops onoccasion, my scleritis did not return for several weeks, but it did return asepiscleritis, which is a milder form of scleritis). Recently, I stopped dietarytaurine, and the scleritis returned the following morning. To reduce theseverity of scleritis, one can try 6 grams of pure taurine with each meal andat bedtime for a few weeks. Ihave found some evidence that intestinal yeast overgrowth will cause thekidneys to be unable to recycle taurine, with taurine being lost into theurine. Yeast overgrowth of the intestines is also blamed for many of thearthritic-like complaints often found with scleritis, and is the likely causeof scleritis. Consequently, any effective treatment for Candida yeast shouldalso prevent scleritis. I have found that coconut oil andgarlic areeffective, particularly when used with taurine. Taurine in these doses shouldnot be considered nutritional in nature, but medicinal, and I dont recommendit. The human body only contains 70 grams of taurine, and supplements of 24grams per day seem much too high and I took that dosage for only several weeks.Actually, I think that anything that treats inflammatory or irritable boweldisorders would be beneficial in treating or preventing scleritis. However, Kefir is theabsolute cats meow for preventing and curing scleritis. Since I started Kefir(I backed off garlic and coconut oil completely), I have had zero incidence ofscleritis (for many months now), thus showing, IMHO, that taurine preservationby elimination of Candida Albicans using Kefir is vital to the cure forscleritis. Drymouth and dry eyes are some of the most irritating side effects of manyprescription anti-depressant drugs (and some other drugs). Dry mouth and dryeyes are usually symptoms of magnesium (and possibly potassium and taurine)deficiency. Dry mouth and dry eyes are very easily treated with oral ionizablemagnesium - the nutrient your body is likely starving for. Use of synthetictears and other simplistic wetting techniques including chewing gum are notsolving the nutritional deficits that cause the problem. Magnesium and highpotassium content foods such as bananas, potatoes and other whole foods aregreatly preferable to drugs. I have found that my health improved greatlysimply by using balanced potassium/sodium salts [Mortons Lite Salt -which contains iodide (iodine)] rather than by using plain table salt(sodium chloride). Use of plain table salt can easily lead to imbalancesbetween potassium and sodium. Dry mouth can also cause dental caries. Althoughcalcium is necessary as a component of teeth, it does not play the major rolein preventing dental caries, as is popularly supposed, but magnesium does. Magnesiumis mandatory for strong teeth and bones, and without it or with inadequateamounts, caries form. In fact, dental caries and tartar formation can becompletely prevented for years with a high magnesium diet. Dry mouth and dryeyes, particularly when coupled with insomnia often precede other better-knownmagnesium deficiency symptoms. If promptly treated with magnesium more seriousmagnesium deficiency disorders such as anxiety and depression can beprevented. Succeed! Depression is not a psychosis! Stress Relief Techniques Perhapsthe obvious needs to be stated. Stress hurts us if we dont know how to getrelief. We have let stress hurt us and build up in us by not taking affirmativeaction at the right time. Stress has built up in us until we became seriouslyill and magnesium depleted. There are many stress coping skills that we havenot yet mastered, or we would not be ill. Environmental, physical, metabolicand psychological stressors are around us every day. We can try to limit thesestressors and/or we can learn to deal with them. Metabolic stress can bedirectly dealt with using magnesium, and limiting our intake of calcium.Physical and environmental traumas happen. We can plan to deal with some ofthese by taking extra magnesium before hand, or immediately afterward.Psychological stressors can be dealt with magnesium too. However, forgivenessis key to overcoming the "fight or flight" stress reaction toaggravation, anger and anxiety caused by other people. A certain amount of painis inevitable in life, but suffering is optional. Do not letanger get you down! Personally, I really like magnesium taurate as an "aspirin for theemotions". Include in your stress relief tool kit: Say this little prayer: "Oh Lord, grant me the courage to change the things I can change, the serenity to accept the things I cant change, and the wisdom to know the difference." Consider others: If you think you have problems, then you need to see this picture of me having a really bad day! Consider your problems in relationship to the problems of others. How do others handle their problems? Dont be so hard on yourself when you screw up. Heaven knows, these guys didnt! However, be aware that too big a screw-up is likely to have serious repercussions, like this cartoon of Bush leadership in Iraq shows. Nobody is more obsessive than George W. Bush according to this cartoon, so dont feel you are too obsessive to function. Just take magnesium and taurine and get over it. Talking about George Bush and Iraq, why is it that every time I think of him, I have a mental image of Pee Wee Herman and his big adventure? Walk: Walking is the number one choice for stress relief. Take a walk in the park or on the beach. Nature can be very relaxing and is so easy on the eyes. Feel the breeze lift your hair and gently stroke your face. Some researchers have reported that walking increases temporarily magnesium in blood serum. Recreate: Go to a gym, or do a sport such as tennis, hiking, golf or running. Ride a horse, therapeutically, not like this girl unless you are an expert. Learn the joy of simple pleasures, like my horses did when they discovered snow. Watch this short movie of my horses first joyous experience in snow! Swim: Swimming with its obligatory regular slow breathing is excellent for relaxation. Breathing exercises: Breath in slowly and deeply through your nose, then slowly breath out through your mouth. Imagine all of the tension flow out of you as you exhale. Try this while you are walking or swimming for a double whammy on stress. Massage and aromatherapy: Let someone take care of you. It feels so gooood. Smoking: Cigarette usage is stupid; but smoking promotes slow, conscious inhaling and slow, conscious exhaling, which is probably the reason smokers believe that cigarettes are relaxing. Disciplines: Yoga, Meditation, Tai Chi, Dancing, Bioenergetics Classes all have utility in stress reduction. Credit management: Destroy all of your credit cards. Do not live on credit. Pay them off or declare bankruptcy and get an honest, legal clean start. Have fun: Fun is not a dirty word. Play! Do something you used to do as a child or long ago before you had all of the commitments. Find your old electric train set and play with it. Or, go to a carnival, circus, water recreation park, and while you are there eat some cotton candy. Get busy: Do something you like, such as shopping or go to a movie or dancing. Treat yourself: Buy a new outfit, a haircut, an all day spa. If you are a handy guy, buy some new power tools and make something for someone. Talk it out: Clergy, counselors and psychologists listen well. Knowing someone else understands and hears you without judging you is valuable. Sleep more: Four hundred mg of magnesium (as magnesium taurate) taken an hour before bedtime will give you the best sleep you have ever had. Lack of sleep leads to stress, creating a vicious cycle. More sleep can leave you stress free. Eat right: Eat a well-balanced meal, with plenty of fresh cold-water fish, nuts, fruits and vegetable. When you shop for food, do not buy anything that is not a fresh, whole food. Avoid the SAD Western diet. Avoid the processed food isles. Forget the Twinkies, white bread, cookies, canned food, and literally all processed foods. You would be surprised at how much weight can be lost simply by not eating processed foods, which are depleted of magnesium and other shelf-life damaging minerals. Your appetite will become lessened and your stomach flatter when on a high magnesium diet. Loosing weight with a high magnesium diet is usually easy and natural. Avoid foods high in calcium for a while. Avoid brain poisons: Avoid foods and drinks that contain Aspartame or monosodium glutamate (ask about foods at restaurants, and read labels). They are excitotoxins and can cause or worsen depression. To satisfy a sweet tooth, and avoid aggravating depression, always use Stevia, the ultra safe, herbal, top secret, super-sweetener that the FDA doesnt want you to know about. Stretch: You can feel the stress leave your body. Take time for yourself: Dont keep giving and giving. Take time for yourself. Get away. Take a trip. Take a vacation. Simplify, simplify, simplify! Simplifying and prioritizing is essential to stress relief, particularly for those of us that tend to be a bit on the bi-polar or ADHA side. Lest we run around in circles looking like crazy people! Get closer to God: Biblical faith in our Father is an enormous stress reliever; cast your cares on Him that can handle them. Read Psalm 66 and 96. Read and understand the truth and wonderment of reality: Read the Book of Tao. Above all, be a lover of truth: Be like the Sufi. Focus, visual relaxation: Close your eyes and imagine you are somewhere nice that you choose such as on a deserted island walking along the shore or skiing on a snow covered slope with the cold brisk wind in your face or whatever you like to do. Positive attitude: Look at things in a more positive and forgiving light. Always think of something positive when you would prefer to dwell on the negative. TV as poison: Flip the channel on bad news on TV and other media. Dont watch it. It has nothing to do with your life. Watch the PAX TV, The Discovery channels, including the Learning, Travel, Animal Planet, Health and History channels, Horse TV, religious or science channels. Avoid the hard metal rock music channels with their songs of twisted minds. Imagination: Dont let your imagination run away with you. Never dwell on negative things that could happen, such as disasters or tragedies. Imagining the worst often causes it to occur. Ask and ye shall receive! Smile and laugh more: Think up a joke and tell it to a friend or spouse. Laughter is the Best Medicine. Laugh at other peoples jokes, but not disingenuously. Laughter is a medical necessity. Perhaps because laughter is beneficial to your immune system too. Here is a joke that I recently dreamed in my sleep. There was a Viet Nam vet that had been totally insane for 30 years since being held in a 4-foot bamboo tiger cage by the Viet Cong. One day a young V.A. doctor gave him some new medicine. The vet immediately jumped up saying he was totally well! All of the insanity was gone! He was absolutely thrilled. When he asked what was in the medicine, the doctor said, "Extract of bamboo". Moral? Magnesium allows one to remember dreams. Enjoy some black humor. Remember Gloria Gaynors song "I will survive"? It was a 1979 disco classic. It is now available on the web as a spoof called "Alien Song", which is a little mpeg that has a surprise ending. An ending that is predictive of all future endings, but not an ending for today. Get organized. Try organizing your closet, office or garage. Lighten up your clothing color scheme: Whites and yellows and light blues with neat patterns are proven to be happy colors, as opposed to reds, blacks, brown, gray and dark blues. Dont let people get to you: Most people have problems and they sometimes try taking it out on others. Its not your problem, so why accept it as yours? Its garbage and useless baggage. Dump it where it belongs. Sex: Sex is a positive stressor, which relieves negative stress. Read: Get caught in a love story or in a "who done it" story, escape for a little while. Plan for your period: Zinc prevents menstrual cramps and bloating. Magnesium is important in treating PMS. Find your passion in life: Get a hobby like painting, gardening, writing, cooking, etc. Work smarter not harder: Leave stressful professions and their baggage behind, get a real life. Illegal street drugs. Bliss for a moment, pain and crime for life. Only the most stupid, foolish and dying do street drugs. There is only one time in life when cocaine is appropriate. Cults: Run for your life. They only immerse you with their own problems and agendas, which make your problems seem insignificant. Psychiatrists: Bash your psychiatrist with magnesium . Why? Most have become "drug pushers" in disguise. They are not to blame for not knowing about magnesium and its curative powers because no drug company promotes magnesium because it is not patentable. Magnesium adoption into psychiatry would devastate the lucrative anti-depressant drug trade. After ruling out diseases and hormonal disorders that can cause depression, trying magnesium taurate, stress relief and seeing a nutritionist and a psychologist before seeing a psychiatrist seems reasonable to me. Psychiatrists would be much more valuable if they learned about magnesium and its related brain biochemistry, than prescribing SSRIs which act mainly as placebos. The first thing my psychiatrist did when I told him about magnesium curing me, was call a poison control center hot-line! He had no idea! And your shrink wont have a clue either. Rather than congratulating you on your progress on magnesium, he/she will likely ridicule you and possibly intimidate you to get you hooked on drugs. In my opinion, prescribing powerful psychoactive drugs having major side effects for depression, bi-polar, and ADHD and related disorders without prescribing magnesium taurate to treat benefit the "structure or function" of the body or the "well-being" magnesium depletion masquerading as these mental illness will someday be recognized and considered malpractice. Perhaps other mental conditions are also nutrient deficiencies. Perhaps consideration should be given to whether psychiatry is even a legitimate medical field. Don Weitz has listed 25 good reasons why psychiatry must be abolished. Try practicing Emotional Freedom Technique, or EFT. This is a psychological acupressure technique. You will not achieve your bodys ideal healing and preventative powers if emotional barriers stand in your way. Visit "stress relief strategy" web sites: Simply learning about stress relief strategies that others have learned the hard way is helpful. Succeed! Depression is not a psychosis!Understress,Optimal Stress, and Overstress To this point I seem to have implied that "stress" is bad and harmfulto health. Please forgive me because that is incorrect. It is only"overstress" that is very harmful to health and can cause magnesiumdepletion leading to anxiety, heart attacks, depression and death (selfinflicted or heart attack). People require a certain level of stress in theirlives for happiness. Just as a violins strings must have the correct tensionto sound perfect, people must have the correct tension (stress) too. Although"understress" rarely leads to illness from magnesium depletion, ittoo can be a life-threatening problem. Understressed people tend to be workingand living well below their potential or desired life style thus resulting inboredom, apathy, and other characteristics, some of which are shown below.Optimal stress is the amount of stress that leads to a full life, filled withchallenge, excitement, satisfaction and pleasure. As discussed throughout thispage, it is "overstress" that causes magnesium depletion healthproblems. > Understressed Optimal Stress Overstressed Boredom Exhilaration Insomnia Overqualified for work High motivation Irritability Apathy Mental alertness Accidents Erratic, interrupted sleep High energy Alcoholism Irritability Realistic analysis of problems Absenteeism Decrease in motivation Improved memory and recall Change in appetite Accidents Sharp perception Apathy Alcoholism Calmness under pressure Strained relationships Absenteeism Good relationships Poor judgment Change in appetite Accuracy Increased errors Lethargy Happiness Lack of clarity Negativity Can do attitude Indecisiveness Loneliness, unwanted Appreciates solitude Withdrawal Dullness Cooperative Feeling of falling Increased errors Dedication Loss of perspective Seeks distractions In harmony Diminished memory and recall Low muscle tone Ready to react muscles Tense, strained muscles Anxiety, depression, suicide Content, happy fulfilled lives Anxiety, depression, suicide As we examine the above table from the 1981 book "Stress/Unstress" byKeith W. Sehnert, MD, we can see that people can have stress characteristicsthat are listed in both the overstressed and understressed columns. Alcoholism,appetite problems, irritability, sleep problems, anxiety, depression andsuicide occur in people not optimally stressed. Does alcoholism in theunderstressed and overstressed result in loss of magnesium? Yes; in 60 to 80%%of alcoholics, and it is usually accompanied by liver or kidney damage. Current belief isethanol acts generally in the brain by reducing free magnesium levels, anddirectly at hydrophobic sites on brain proteins to cause acute intoxication bypotentiation of inhibitory GABAA receptors, inhibition of excitatory NMDA-typeglutamate receptors, 5-HT3 and adenosine receptors, and 5-HT uptake sites,according to University of Texas Tech pharmacologist, Peter J. Syapin. How doesintelligence, loneliness, education, sexuality, and physical, mental andspiritual health relate to our ability to handle stress? These parametersdefinitely influence our ability or inability to handle stress. Perhapseducating a person would shift his paradigms in beneficial ways, by allowinghim/her to be employed in more interesting work, and/or associate with a moreenthusiastic, happy, loving or spiritual group of people. On the other hand,over-education for a job would usually result in an understressed situation andthe person could become bored. Alternately, excessive education and reductionto logic can leave a person wondering who he/she is. Such concept of selfalienation through education was memorialized by the British rock bandSupertramp in their amazing "The Logical Song" 0.54MB.wav 5.9MB.wma in thelate 1970s. Follow the words here. Boredom,a major characteristic of understress, causes people to seek distractions fromtheir boring lives. Some "distractions" include but are not limitedto drugs, alcohol, smoking, gambling, sex, violence, and sports, all beingmajor industries. Severe, prolonged boredom can eventually cause anxiety,depression and suicide, but probably not from magnesium depletion. If boredom isa problem, then visiting some of the 400,000web pages on "boredom" is for you. Most are boring, but the Boredom Institute is quite interestingand potentially helpful; and quotes William J. Bennett, in the "Death ofOutrage" as saying: "Inliving memory, the chief threats to American democracy have come from without;first, Nazism and Japanese imperialism, and, later, Soviet communism. But thesewars, hot and cold, ended in spectacular American victories. The threats we nowface are from within. They are far different, more difficult to detect, moreinsidious: decadence, cynicism, and boredom." We all know people that seem totally immune to the effects of what we wouldcall an overly stressful situation. For example, George W. Bush makes being thePresident of the United States look like an easy job, whether you agree withhis politics or not. Of which other Presidents can that be said? Other peopleare overstressed simply by being asked to work an hour longer a day for awhile, or awaken an hour earlier than usual. They resent it and are openlyunhappy about the "overwhelming" load they are forced to carry.Consequently, we can see that different people have different"scopes", or carrying capacities for stress. Some people are vastlyflexible and can carry many varied responsibilities without suffering fromstress overload. Others can not. It is human nature and nurture. Adding to thecomplexity, the carrying capacity for stress varies at different stages oflife. Generally, neither the child can carry the stress burden of a matureadult, nor can the very elderly, but even here there are exceptions. We can allthink of child prodigies such as Charlotte Church(perhaps the greatest singer alive and only 13 years old), and retiring 81 yearold Senator Jesse Helms.What can we do to increase our scope? Beyond education, a disciplinedmind and heart, and healthy eating and living, I am not certain that Iknow. Is magnesium supplementation the general answer to increasing our scope? Yes,because people deficient in magnesium have difficulty learning, and retainingknowledge. Optimally stressed and understressed people will also benefit frommagnesium supplementation if they are deficient; and there is evidence that magnesium deficiency isrampant in our society, causing hundreds of specific health problems listed.Magnesium depletion will occur regardless of stress if the diet is low orabsent in magnesium and/or there is an excess of calcium. Overall, men inWestern cultures are believed to have a shortfall of about 100-mg magnesiumfrom their diet per day and slightly larger shortfall for women. With so muchto gain and nothing to lose, it seems like the NIH and other health agencieswould become much more interested in promoting magnesium - for health. Succeed! Depression is not a psychosis! An Aspirin for the Emotions I have found that magnesium taurate is as effective and quick in treatingbenefiting the "structure or function" of the body or the"well-being" stress (objectionable and debilitating, acute,emotional problems such as anger, fear, rage, depression, and anxiety) asaspirin is effective in getting rid of simple headaches. I call magnesium an"aspirin for the emotions". For example, If something makes me veryupset (stressed) for real and legitimately reasons (or otherwise), that if Itake a magnesium taurate tablet, the problem becomes much more manageable; andmy head is cleared of the negativity that makes dealing with those stressfulsituations difficult. March 19, 2001 was the most difficult, emotionallydraining, frustrating, aggravating, irritating day that I have experienced inmany years. I took 200 mg magnesium about 6 times during the day and evening toovercome those stressors throughout the day with no side effects. Each time themagnesium seemed to work to alleviate the bad feelings, and those feelings weredissipated before they could reinforce each other and really make things worse.It works every time in many more people reporting than only me. To get throughthe stress of the Attack on America, I needed 1800 mg of magnesium per day. Succeed! Depression is not a psychosis! Headaches Treating headaches with magnesium should be obvious to the reader by now. Doesmagnesium work for migraine headaches? Researchers have found that patients whosuffer with migraines also suffer with lowmagnesium levels and high calcium. In fact, most chronic headaches arecaused by high calcium and low magnesium. When treated with IV magnesium 88% ofthose patients found complete relief of their migraines. Low-ionizedmagnesium and high-ionized calcium/magnesium ratios in patients withdaily migrainous headaches are frequently noted. Since starting http://www.headachepainfree.comweb site in September of 2000, Shawna Kopchu RN, its director, has given adviceto hundreds of migraine patients on the use of magnesium for their migraines.Out of those patients - ALL of them got some sort of relief with the use ofmagnesium. Some were completely cured and others found that it decreased thefrequency and intensity of the migraines they did get. Magnesium tauratemay be preferable to other forms of magnesium in its treatment effectson "structure or function" of the body or the "well-being"of migraines. I have also found that regular use of magnesium prevents headaches. Since Istarted using magnesium for depression, I have not had a headache (unless I didsomething really stupid - for which I deserved a good headache). I have afriend that suffered from cluster headaches,the worst and most debilitating type of headache known to humans. People havecommitted suicide to be free of them. This person was really irritable (a clearsign of magnesium deficiency) and would not take magnesium, saying that if thebest doctors in the field could not cure his headaches, why would he evenlisten to me? He suffered horrible cluster headaches for another year, and wassuffering from some prescription drug overdoses and bad side effects. Finally,his girlfriend told him (after I had proselytized her for that year), that shewas going to leave him if he didnt give magnesium a good college try. OK. He wasin so much pain that he laid down on the floor. I did too. He knew my positionon magnesium already and all he wanted to know was the dosage. I told him thatif I were him, I would take, at least in the beginning, 400-mg ionizablemagnesium three times a day (breakfast, mid afternoon and bedtime) totaling1200 mg magnesium. I told him that he would eventually get diarrhea at thatdosage, and that he should back off to a more sustainable dosage in about aweek. I told him to avoid the toxic forms ofmagnesium, which would probably make his headaches worse. I also toldhim to avoid man-made glutamatesand cut down on calcium.I didnt see them for several days, then, I heard a loud and very rapidknocking on my door about midnight. It was my friend and his girlfriend, andthey were tripping over each other trying to be first to explosively andjoyfully tell me the good news! NO MORE HEADACHES! PERIOD!!!!!!!! Not even aminor headache! What more can I say. Chronic headaches without clearexplanation (like a well deserved hangover) are just another symptom of our sick,over-medicated, magnesium deficient society. Can you imagine the financiallosses that would be incurred by pharmaceutical drug pushers if the truth wereknown about magnesium and its critical role in health? I suspect they woulddeclare magnesium to be toxic and force the FDA to take it off the market. Thismay happen due to the Codextreaty. Succeed! Depression is not a psychosis! Epsom Salts Baths First discovered in the townwell of Epsom, England and patented in the 17th century for its healingand curative powers, Epsomsalt baths are the oldest and cheapest ways of relaxing muscles andsettling nerves. Simply add two cups (1 pound, 454 grams, 16 oz., 1 pint, 1/2liter, 500 ml) to your warm bath water to make a standard Epsom salt bath, andenjoy! To make a strong Epsom salt bath, double to quadruple the amount ofEpsom salt. To make a VERY strong bath, double it again. Like our friend TeddyBear here, Epsom salt baths have produced pleasure for millions for a very longtime - at least three hundred and fifty years. One of the coolest ladies that Iknow takes one every 5 days, whether she needs it or not, because it is part ofher routine for staying well. Even today, Epsom salt is the primary ingredientin nearly all expensive relaxing bath salts. The crystals are 10 percent puremagnesium, and a rounded 1/2 tablespoon (7.2 milliliter) yields 1 gram ofmagnesium. It is one of the most highly absorbed magnesium compounds known(easily absorbed through the skin or digestive tract). The effect of thesebaths has not been understood from a neuroscience aspect until recently. Thesebaths can raise blood and tissue levels of magnesium, resulting in the feelingof well being and relaxation, and perhaps sedation in overdose for all thereasons stated in this essay for orally ingested magnesium. Few who use Epsomsalt baths judiciously for relaxation go away unhappy. Now, you can buy yourown sensory deprivation tankand fill it with Epsom Salts and really space out! AlthoughI found no clinical evidence of using Epsom salt baths to treat clinicalanxiety or depression, in theory there is no reason why, with experimentation,such would not work, and perhaps work very, very well. The trick to success maybe simply finding the correct strength. Should one use a standard or strongEpsom salt bath? I think a VERY strong one is best, when done with modestcaution. The main side effect of prolonged strong Epsom salt baths, other thanrelaxing to the point where one falls asleep, is diarrhea. Taking a VERY strongEpsom salt water bath without someone ready to watch the person is unwise, andcould lead to overdose, sleep and drowning. Too long spent in very strong Epsomsalt baths will put a person on the commode with diarrhea for at least a halfhour. What is too long? I think about 20 minutes of a VERY strong bath is longenough, and 60 minutes may result in diarrhea because of the very strongwater-drawing capability of the magnesium ion. How frequently should strongEpsom salt baths be taken to treat depression? Daily? Several times daily?Perhaps. Four to six times daily? Lets not over do it, but maybe for a week ortwo in the beginning. Epsom salts are of particular value to people outside of the United Stateswhere there are fewer medicinal or nutritional forms of magnesium. Epsom saltalong with magnesium chloride are found using industrial, agricultural,medicinal and veterinary sources world-wide. America has stepped around theseold standbys as if they were unimportant, which is a shame. Strong Epsom saltmay draw out water from the skin, causing temporarily dry skin in overdose.Severe overdose (resulting in flushing of the skin, thirst, low blood pressure,loss of reflexes and respiratory depression, anesthesia (and eventually heartfailure if untreated) are countered with intravenous calcium gluconate in ahospital. Seriously, the benefits of judicious use of Epsom Salt baths faroutweigh the risks. Think of the opportunities for pleasure! Here are 13wonderful ways to use Epsomsalt. Epsom salt baths or topical rinses are used for many purposes inmedicine and veterinary medicine. In people, Epsom salt are routinely used for:soothing relief from arthritic pain; reducing stiffness, soreness, andtightness of joints; improving discomfort from muscle aches, pains andtenderness; soothing painful bruises, sprains and strains; alleviating painfrom over exertion during sport activities; improving the bodys sleeping andresting productivity; increasing and improving body energy levels; improvingthe rate of natural body healing; soothing away stress; deep cleaning skin andpores; taking the sting out of insect bites and drawing out splinters. Ifbathing to get your magnesium does not appeal, then dissolving a rounded 1/2tablespoon (7.2 milliliter) of Epsom salt (yielding 1 gram of magnesium), canbe dissolved in 1 cup (8 oz., 1/4 liter, 250 mL water). This prepares a strongstock of magnesium mineral water, which can be added an ounce or two at a timeto other beverages to prepare very inexpensive and highly nourishing magnesiumdrinks. Do not try to swallow crystals. Thinksomething as "natural" as Epsom Salts cant hurt you? Review this case of a fatalityinduced by using an entire box of Epsom Salts over a 2-day period as a garglefor halitosis. Succeed! Depression is not a psychosis! The Mind The mind, consciousness, is a funny thing. It is neither space, time, matternor energy, but a separate entity all of its own. Mind has been shown to be ableto affect changes in energy and matter, and perhaps time and space. The mind isthe only non-Newtonian part of the body and it is of a quantum mechanicnature. The realm of the mind is in the vast collection of microtubules ofneuronal synapses, an area solely of a quantum and/or post quantum mechanicsnature; an area quite sensitive to magnesium concentration. Quantum mechanics,not Newtonian science and calcium channel blocking in the vastly largersynapses, offers the best chance to understand the interactions ofconsciousness with the Universe. Some have speculated that our own individualconsciousness is not found solely in our own brains, but in the nonlocality of theUniverse. There are many Internet sites devoted to "consciousness"and "quantum mechanics". One excellent, but long (slow PDFdownload), 1995 report by the Center for Theoretical Physics, Texas A&MUniversity and others is "Theory of BrainFunction, Quantum Mechanics and Superstrings". There are mind-matter interactionsdemonstrable in delicate scientific equipment, proven by eminent academic andgovernment scientists. Cells (human, animal, and plant) have been caught in theact ofcommunication with their host even if they have been taken miles awayfrom their host. Succeed! Depression is not a psychosis! The Creation of Adam - Michelangelo The Creation of Adam (1508-1512) on the ceiling of the Sistine Chapel has longbeen recognized as one of the worlds great art treasures. In 1990 Frank LynnMeshberger, M.D. described what millions had overlooked for centuries - ananatomically accurate image of the human brain was portrayed behind God. Onclose examination, borders in the painting correlate with sulci in the innerand outer surface of the brain, the brain stem, the basilar artery, thepituitary gland and the optic chiasm. Gods hand does not touch Adam, yet Adamis already alive as if the spark of life is being transmitted across a synapticcleft.* Below the right arm of God is a sad angel in an area of the brain thatis sometimes activated on PET scans when someone experiences a sad thought. Godis superimposed over the limbic system, the emotional center of the brain andpossibly the anatomical counterpart of the human soul. Gods right arm extendsto the prefrontal cortex, the most creative and most uniquely human region ofthe brain. *FrankLynn Meshberger, M.D., The Interpretation of Michelangelos Creation of Adam,Basilar Neuroanatomy, JAMA #14 October 1990. Succeed! Depression is not a psychosis! Suicide There is no act more selfish than suicide. It hurts those that we love inperpetuity. Can you imagine your spouse, mother, father, brother, sistershowing up dead by their own hand? How about your child? Dead of his/her ownhand? Isnt that the most shattering thought? Considering suicide? Consider howyour loved ones will feel, then get a bottle of magnesium - not poison. Thinkof how you would feel if one of your loved ones committed suicide. Treatyourself as you would like your loved ones to treat themselves. Isnt thisnotion similar to the Bibles Golden Rule - "Treatothers as you would like to be treated."? Would you be surprisedif such thoughts were caused by magnesium depletion, and not your psyche? I can understand that a deficiency in a nutrient could adversely affect ourability to think, but can it affect what we think? Why does magnesiumdepletion cause people to think of suicide and actually commit suicide? Medicalliterature from 1985 clearly shows that calcium/magnesium imbalanceswith magnesium being low were found in depressed patients that had attemptedsuicide. If we go back in time farther - to articles and books published beforethe National Institute of Health started indexing medical articles in PubMed,other researchers showed more about how magnesium deficiency promotes suicide.Why this research has been ignored is another travesty. Did you know that the American Psychological Association doesnot mention "magnesium" in its web site? With so little currentinterest, could we expect anything different? Considerable research fromearlier in this century by various scientists needs vastly more consideration. For example, French scientist, M. L. Robinet, in a study of suicide statistics,discovered that "the comparison of geological maps and statisticsestablishes in a striking manner the influence of the magnesium content of thesoil on the number of suicides. It is evident," M. Robinet points out,"that one doesnt commit suicide because the soil is poor in magnesium.But, those who regularly absorb a good amount of magnesium salts have a morestable equilibrium, they support adversity with more calm and do not renounceeverything to avoid some sorrow. "The use of magnesium permits one tosupport adversity with more serenity," M. Robinet concludes in theBulletin of the Academy of Medicine published in France (1934). Magnesium, says Dr. Lewis B. Barnett, is needed by the pituitary gland. Thepituitary, sometimes called the miracle gland, takes instructions from thehypothalamus in the brain to which it is connected by a thin stalk, thentransmits them through the body in the form of chemical messengers known ashormones. These hormones not only exert a direct influence of their own, butalso trigger the production of other vital hormones elsewhere in the body. Whenthe pituitary is not getting the magnesium it needs, it fails in its functionof exercising a sort of thermostatic control over the adrenals which are thusallowed to overproduce adrenaline (a major stress hormone). It is known thatsituations of danger incite the activity of the adrenal glands. Troubles orworry also incite the adrenal glands, which then pour hormones through the bodythat increase heartbeat, release sugar from the liver, and contribute to a hostof problems not the least of which is hyperexcitability and an inability to"cope." According to some startling data presented at the meeting of the AmericanSocieties for Experimental Biology in May, 1966 the adrenal glands alsocontribute to the desire of a suicide to cut himself away from life. Evidencewas presented at this conference that showed how, in the split instant of finaldecision to take his life, it is the adrenal glands rather than the psyche thatgive that last little push. "Successful suicides had highly active adrenalglands just before their deaths. That discovery fits neatly into otherobservations that depressed patients--those most likely to commit suicide--alsohave more adrenal hormone in their blood than do normal persons," reportsEarl Ubell, science editor of the Herald Tribune (May, 1966). Oneinvestigation revealed that, just before attempting suicide, depressed patientsexperience a rapid rise of adrenal breakdown products in the urine. As reportedin that study, a laboratory made measurements on one woman, found anextraordinarily high hormone level, and called her home to warn her family onlyto find she had already killed herself. What can be done to prevent thisadrenaline rush? As far as I can tell, the only way is to eliminate stimulants,particularly chocolate, from the diet. Death by chocolate seems far fetched, butit does release theobromine, a relative of caffeine, and phenylalanine which isa building block for dopamineand adrenaline.Who knows the number of deaths by chocolate? No one, but for suicidal and insomniac peoplethat have too much adrenaline and low magnesium, avoiding chocolate seemsreasonable, and may be life saving. Remember that Durlachshowed that aging is a risk factor for magnesium deficiency. Those that studyaging know that suicide is a major cause of death among old people. Every 90minutes in the United States a person over age 65 commits suicide. Rememberthat 90% of suicides occur in people with depression. Remember that about 20%of seniors are afflicted by depression, roughly in keeping with the percentageof elderly people known to be magnesium depleted. In addition to chronic lowmagnesium, many non-dietary causes of hypomagnesia result from medical conditionsthat often accumulate as a result of aging. Consequently, in older adults(particularly those without close relatives or loved ones), conditions areright for an older person to forcefully desire suicide. What can we do? Itseems to me that very close attention to magnesium status of older peopleshowing signs of depression is appropriate. Who will administer magnesium toour older, isolated seniors already considering suicide as a cure for their depression?What else can we do to prevent these horrifying thoughts? Is seeing a physicianthe answer? Consider these amazing facts first. Suicide rates are very high in physicians.Overall, the physician suicide rate is about 3 percent of male physicians and 6percent of female physicians. Worse, a study by Dr. Daniel DeSole of theVeterans Administration Hospital in Albany showed that 26 percent of all deathsamong physicians 25 to 39 years of age were suicides. This compares to a rateof 9 percent for white males in the same age group. Physicians are underenormous stress and stress kills. Not knowing the role of magnesium in mentalhealth is killing our doctors. Can you guess which medical specialty has themost suicides? Psychiatrists! For more on doctors killing themselves see this search.To see what doctors are teaching each other about suicide see this education link.On the other hand, a search for "nutritionistsuicide" comes up with zero meaningful entries! Does this meannutritionists do not kill themselves? Hummmm. Maybe there is something to belearned here. Succeed! Depression is not a psychosis! Meditation vs. Thought-Stopping Mostof us have heard of "meditation",but how many of us have heard of its opposite, "thought-stopping"?Is there an important difference? YES! Meditation and thought-stopping are bothfound in religion and psychology. They relate to the way we treat our ownthinking. Our job is to know when to use each technique. In meditation, we letwhatever will enter our minds enter. In thought-stopping, we control what is inour minds. Which is better? To me, a depressive, the answer is very clear. Iwill not surrender my mind to whatever thought I might have and surrendermyself to whatever emotion such thought produces. I demand control of my ownmind. It is mine! I will not allow religion or my early childhood training toforce me to accept whatever thought that occurs to me. It doesnt need to workthat way. Meditation, supposedly, is an unguided, unintentional, sustainedfantasy or mental state of reflection and contemplation. It is supposed to be arelaxing experience, a "quiet time," a self-paced desensitizationprocess. For people without mood disorder, it is often a productive endeavor;but for people with mood disorders, we must use another technique. According toBernhardt,when using emotional thought-stopping, negative thoughts from the unconsciousare cut off the very second they present, PERIOD! This technique demands thatwhenever we have a negative thought, we slam dunk it into oblivion withcommands such as STOP! DONT GO THERE! ERASE THAT THOUGHT! SHUT UP! Letno negative thought go unchallenged 24-7 or it will produce a negative emotion.Never let yourself stew in your own negativity. Isnt that a much betterapproach for a depressive than to meditate and let whatever thought that comesto you take over your existence? Can thought-stopping be useful in forms ofanxiety such as OCD? I think so. Consider changing a repetitive thought oraction to something less harmful or obvious. For example, suppose a person hasan obsessive thought about how badly someone has wronged him/her. That thoughtis driving him/her crazy! When such thought occurs, why not try to bog down themind with a challenging substitute thought instead? Obviously, there are manythoughts that can bog us down, but we know they do not have answers (such aswhere is the beginning and end of the Universe), and we should not considerthose kinds of question as useful thought-stoppers. Leave them to theprofessionals. However, we can really bog down our minds with distractingmental quests such as: list all words that start with the letters"re". I will start the list for you. Re-examine, reflect, restart,reconsider, reconcile, revamp, revisit... Get the idea? Read "BrainLock" by Dr. Jeffrey M. Schwartz for more . By the way, dont thecommands I mentioned above in bold sound a lot like the commands we give ourchildren when they are misbehaving? Succeed! Depression is not a psychosis! Losing Your IQ? (Or Your Childrens IQ?) Since you arereading this page, you are concerned about mental function and magnesium. Doesthis graphic get your attention? This is what happens to the intelligencequotient (IQ) of children living in a highly stressed orphanage compared withkids living at home. Nothing is more harmful to IQ than stress! It drives downmagnesium so intensely that these children loose their IQ. Yet, we keep pilingstress on our children and ask them to like it. Are we crazy? Are we stupid?Insane? TheGods Must be Crazy! Notice that the kids that lived at home have anormal distribution of IQ, a bell-shaped curve if you will. The kids livingunder stress have an extremely distorted IQ range, with only a very few havingnormal and better IQ. This data is from Table 3 of "Magnesium and somepsychological features in two groups of pupils", by VictoriaPapadopol, Eugenia Tuchendria and Iliana Palamaru of the Institute of PublicHealth, Iaşi, Romania. In my opinion, these authors deserve a Nobel Prize inMedicine for this truly original research. There are no other papers onmagnesium and intelligence on PubMed.Unfortunately, the last sentence of the articles abstract reads, "Adirect correlation between magnesium level and neuroticism wasdemonstrated." This sentence was grossly mistranslated from the words intheir Conclusions, which read : Our study pointed out a positive connectionbetween magnesium deficit and neuroticism". Neverbefore has there been such a clear and unambiguous relationship betweenintracellular magnesium levels and attention, memory and intelligence shown. Ofgreat interest is the absence of similar relationships between serummagnesium and these parameters. The consequence of not looking in the rightplace for magnesium (intracellular and not serum) has resulted in grave mentaland emotional damage to our children. For the statistician the p valuesare (p=0.000), which means extreme statistical significant andmeaningfulness. Pay attention to them concerning the role of low magnesium incausing neuropsychological disorders in children including: agitation, anxiety,depression, irritability, weakness, fatigue, confusion, asthenia (loss ofstrength), sleepnessless, headache, convulsive, nervous attacks, delirium,hallucinations and hyperexcitablity. In my opinion, ignoring low magnesium iscriminal and is going to destroy America and the Western world if emergencyaction is not taken to change our childrens diets to get them more magnesiumto withstand the stress of American and Western life. Our children are not bad,but their diets are! Magnesiumdeficiency due to stress and/or diet is the number one reason for lowintelligence quotient in American school children and adults. Children that youknow could be doing better in school but dont, are most likely magnesium deficient.Loss of previous well-being from minor magnesium deficits also causeirritability, poor manners, strange behavior, belligerence, moodiness andviolence. Such behavior changes are further confirmation of low magnesium, inboth children and adults, and those problems will only worsen without magnesiumintervention. Have a doctor test their magnesium status and the test willnearly always come back "within the normal range". Why? Magnesium isan intracellular cation. That means that nearly all is inside cells, and not inthe serum where it can be easily tested. The Exatestintracellular magnesium ion test produces sufficient accuracy, but only amagnesium dietary supplement program of 400 to 800 mg lasting a minimum of 6months will confirm low magnesium. If IQ, behavior and test scores improve, aharmful magnesium deficit was corrected. However, one must always avoid toxicand ineffective forms of magnesium listed here. A 10 to50 point increase in IQ if deficient is usual from supplementing magnesium.Think of the countless stressful jobs that have been lost to low performancewhen the individual seemed to offer great potential. More tragic is the lack ofa future - reliant upon a normal or higher IQ - that school children face. Theyare always under stress in school and rarely get sufficient magnesium in theirdiets. Once they become old enough to make up their own minds, they usually stopeating magnesiumrich foods. Instead, they gorge on high calorie junk food and sodaspushed upon them by corporateAmerica. The consequences of corporate Americas attention to ourchildrens pocketbooks? Their magnesium status deteriorates, they gain weight,become more stressed, ostracized, depressed, and violent. Our future is ourchildren and their ability to operate this technology-driven country. Ourfuture as an economic power and viable nation is at stake. Must this nationcontinue to import brain-power from other countries simply because we dontfeed our children correctly? Osama Bin Laden could not have planned a betterway to destroy America than to keep our kids and public magnesium deprived.This topic is too depressing for me to consider further. If you want the fullskinny, there are nearly 500 pages on the Internet devoted to "IQ,intelligence and magnesium". Forget searching PubMedfor useful information on this topic. I only found one item, that being theabove Romainian article. The docs simply dont know, even though the National Institute ofHealth lists "reduced ability to learn" as a facet of magnesiumdeficiency. YES STUPID, JUST KEEP ON STRESSING YOUR KIDS! Succeed! Depression is not a psychosis! Traumatic Brain Injury andMagnesium Perhapsno injury is worse emotionally than traumatic brain injury to a young personfull of life, hope for the future and energy. Traumatic brain injury can put aperson into a vegetative state if sufficiently severe (we all remember theFlorida lady TerriSchiavos horrible incident of a 13-year vegetative state fromtraumatic brain injury), or it can knock the sense out of them - permanently. Trauma is a bluntmechanism that massively elevates the extracellular glutamate levels.Normal extracellular glutamate concentration is about 0.6 micromol/L.Substantial neuronal excitotoxic injury occurs with glutamate concentrations of2 to 5 micromol/L. Traumatic injury to neurons can produce disastrous resultswith the exposure of the normal intracellular glutamate concentrations of about10 µmol/L to the extracellular space. Mechanical injury to a single neuron,therefore, puts all of the neighboring neurons at risk. Significant collateralinjury occurs to surrounding neurons from this type of glutamate release. Onerecent therapeutic strategy is to immediately treat persons with injuries tothe head or spinal column with glutamate receptor blockers to minimize thespread of neuronal death beyond the immediate physically disrupted neurons.Attempts have also been made to affect the various sites of the coupledglutamate receptor itself. Some of these drugs include felbamate, ifenprodil,magnesium, memantine, and nitroglycerin. These "downstream" drugsattempt to influence such intracellular events as free radical formation,nitric oxide formation, proteolysis, endonuclease activity, and ICE-likeprotease formation (an important component in the process leading to programmedcell death, or apoptosis). Iremember a really wonderful story of a very pretty, smart and nice young ladystudying architecture at a Texas university. One day, in a hurry, she didntsee the spilled soft drink at the top of one of the schools huge granite stairsteps. As her fortune would have it, she slipped and fell headfirst down thefull length of the stairs striking her head on each step as she fell. By thetime her 40-pound backpack had separated from her and she was consequently ableto get stopped, she felt pretty woozy and was in significant pain. She made herway to an emergency hospital room where was treated and observed. An MRI showedno injury and she was discharged. Unfortunately, traumatic brain injury had occurredand her ability to remember her lessons was severely impaired. Her effective IQdropped from 140 to about 80, and after a semester of D grades, she dropped outof the University with medical expunction of her bad grades. The University wasclearly at fault legally. But now what? What is a young girl to do with onlylimited IQ? She eventually became depressed, and later found this page. Sheself-treated with magnesium glycinate, with rapid recovery from her depression.Amazingly, she noticed that her short term memory was returning and that shecould remember as well as she could before her traumatic head injury. Shereapplied to the University, was re-accepted and is now making straight Agrades, but she must continue with her magnesium self-treatment or her problemsseem to reoccur. Howcan magnesium be responsible for repair of traumatic brain injury? Wasmagnesium even responsible? Or was it the glycinate? That question remainsdifficult to answer to this day, but new work with rats following diffusetraumatic brain injury by RobertVink, Christine A. OConnor, Alan J. Nimmo and Deanne L. Heath workingat the University of Adelaide in South Australia appears to be shedding newlight on her "miraculous" recovery from traumatic brain injury. Inbrief, Vink et. al. concluded that "posttraumatic magnesium administrationattenuates long-term motor and cognitive deficits after traumatic brain injury,and that this improvement may include some reduction of post-traumatic stressand anxiety." Vink says, "it is now well accepted that magnesium doesdecline in all forms of brain injury (traumatic, stroke, drugs, radiation, etc)and that treatment with magnesium is beneficial to outcome in experimentalanimals." In their article (see figure to right) they show that learningability in rats that received magnesium sulfate (250 micromolar/kg) dosagetreated 30 minutes after injury allowed rats to learn at the same rate asuninjured rats, while untreated injured rats failed to learn. They propose thatthis amazing response is attributed to the role of magnesium in inhibitingsecondary injury factors including amongst others glutamate release, theactivity of NMDA channel, calcium channel, lipid peroxidation, free radicalproduction, edema formation and opening of mitochondrial permeabilitytransition pores. I strongly suspect that administration of magnesium topatients having recent traumatic brain injury will become common-place. Seethis important article in its entirety here. Even thoughthese amazing findings seem to have application to this young girls case,there exists the possibility that traumatic brain injury, regardless of thecause, be it blunt force trauma, stroke, legal and illegal drugs, malnutrition,and aging induces a persistent low magnesium status that is corrected only bysupplementation of magnesium. Dr.Vink is a world-leader in magnesium and inflammation research. He hosted the 10th InternationalMagnesium Symposium September 7 - 11, 2003 in Cairns, Australia. Thismeeting was one of a series of International Magnesium Symposia organized everythree years by the International Society for Development of Magnesium Research(SDRM). This group consists of the world-leaders in magnesium research. Theabstracts of this symposium are available on line here.Selected and generalized topics of interest to us in these abstracts include: clinical relevance of magnesium from gestation to old age estrogen replacement therapy (ERT) risks in magnesium deficiency effects of certain drugs on magnesium balance magnesium and blood-brain barrier magnesium-Vitamin B6 intake reduces central nervous hyperexcitability in children magnesium protection in traumatic brain injury magnesium and the inflammatory response magnesium deficiency on primary tumour growth attenuation of post-traumatic depression/anxiety following diffuse traumatic brain injury effects of oral magnesium therapy in patients with coronary artery disease Optimal dosage of magnesium sulfate for torsades de pointes effects of Mg2+ on cardiac excitation-contraction coupling intracellular magnesium assay correlations to serum and other measures intracellular magnesium in furosemide-treated patients with congestive heart failure outcome of intravenous magnesium therapy in acute mayocardial infarct patients subcutaneous (non-oral) magnesium product for space missions free Mg, plasma membrane and circulating lipids in hypertension comparision of magnesium and statin pharmaceuticals magnesium in essential hypertension Osteoblastic cell growth as a function of Ca2+/Mg2+ ratio bone mineral density and serum magnesium magnesium deficiency and interaction with aminoglycoside and quinolone antibiotics magnesium in sports a functional biological marker is needed for diagnosing magnesium deficiency the relation of birth weight to intracellular magnesium balance of Mg positively correlates with that of Ca magnesium and cancer in clinical practice (update). intracellular magnesium is independent from extracellular availability during proliferation magnesium, insulin resistance and body composition in heathy postmenopausal women clinical efficacy of magnesium supplementation in patients with type 2 diabetes post-cholecystectomy syndrome and magnesium deficiency effect of magnesium diets in ischemic stroke increases in brain intracellular free magnesium concentration after diffuse traumatic brain injury amiloride increases neuronal damage after traumatic brain injury propofol attenuates the neuroprotective effects of magnesium in experimental traumatic brain injury effects of reduced magnesium availability and mild oxidative stress on aging food intake and magnesium intake affect true absorption and endogenous fecal excretion of magnesium serum magnesium levels and dependency/disability in hospitalised elderly patients absorption and effect of the magnesium content of a mineral water about the misdiagnostics of magnesium deficiency magnesium in asthma attack experimentally induced prolonged magnesium deficiency causes osteoporosis modifications of magnesium concentrations in patients with suppurations of the oro-maxilar area Lyme disease and magnesium deficiency magnesium in animal nutrition Mg-content in different plants and the importance of Mg in N2-fixation Havingparticipated in national and international symposia on zinc, I know theenormous value of these kind of symposia, and would love to have attended. Thenext SDRM symposia on magnesium will be: 8th European Magnesium Congress,Cluj-Napoca, Romania, May 25-28, 2004; Gordon Conference, Ventura, USA,January, 2005; 11th International Magnesium Symposium, Osaka, Japan, October22-26, 2006. KathryneE. Saatman, Florence M. Bareyre, M. Sean Grady, and Tracy K. MCIntosh in 2001showed that traumatic brain injury results in a profound decline inintracellular magnesium ion levels that may jeopardize critical cellularfunctions. They examined the consequences of pre-injury magnesium deficiencyand post-traumatic magnesium treatment on injury-induced cytoskeletal damageand cell death at 24 h after injury. Adult male rats were fed either a normal(n 5 24) or magnesium-deficient diet (n 5 16) for 2 wk prior to anesthesia andlateral fluid percussion brain injury (n 5 31) or sham injury (n 5 9). Normallyfed animals were then randomized to receive magnesium chloride (125 mMol, i.v.,n 5 10) or vehicle solution (n 5 11) at 10 min post-injury. Magnesium treatmentreduced cortical cell loss (p , 0.05), cortical alterations inmicrotubule-associated protein-2 (MAP-2) (p , 0.05), and both cortical andhippocampal calpain-mediated spectrin breakdown (p , 0.05 for each region) whencompared to vehicle treatment. Conversely, magnesium deficiency prior to braininjury led to a greater area of cortical cell loss (p , 0.05 compared tovehicle treatment). Moreover, brain injury to magnesium deficient rats resultedin cytoskeletal alterations within the cortex and hippocampus that were notobserved in vehicle- or magnesium-treated animals. These data suggested to themthat cortical cell death and cytoskeletal disruptions in cortical andhippocampal neurons may be sensitive to magnesium status after experimentalbrain injury, and may be mediated in part through modulation of calpains. See fullarticle here. Other Types of Depression Seasonal AffectiveDisorder. What is it? As winter approaches and the daylight lessens,some people experience a form of depression called Seasonal Affective Disorder(SAD) - an extreme case of the "winter blues" that disappears duringthe spring and summer months. About 25% of people get SAD during winter, reallyspoiling their Holiday season. Symptoms may include: Lack of energy Increased desire to sleep Depression Increased appetite leading to weight gain Anxiety Difficulty concentrating Irritability Withdrawal; difficulty with relationships; loss of sexual desire For women, increase in PMS-related symptoms Interestingly,each of these individual symptoms, including PMS-related symptoms, result frommagnesium deficiency. Although the cause of SAD is not clinically proven,various treatments including vitamins, amino acids, magnesium and light therapyhave helped many people, while melatonin usually worsens SAD. Light therapyis rewarding to many, perhaps because it stimulates the production of VitaminD-3, the type of vitamin D produced by action of sunlight on skin.Supplementation of 400 to 800 units of vitamin D-3 resulted in modestimprovement of SAD within 5 days in a clinical trial. If Vitamin D-3deficits from lack of sunlight were the primary cause of SAD, it seems thateven more than 25% of people would be affected by it. Vitamin D-3 is well knownto be required for proper utilization of magnesium, and supplementation ofmagnesium should be a more direct route to recovery from SAD and all of itssymptoms than taking Vitamin D-3. Magnesium dietary deficits are well known toaffect at least 25% of people and in some countries and regions as many as 70%.Supplementation of both Vitamin D-3 and magnesium (400 mg magnesium asmagnesium taurate taken in the morning and at night) may result in even fasterrecovery from SAD. Hereis a poem to the sun from my friend Martha of Marthas Vineyard, who reallyneeds to move to southern California to get more sun: > The Sun is my Prozac I shall not want He maketh me to lie down in warm climates, He restoreth my serotonin He leadeth me out of the winter blues In Him I bake. Thou preparest a path before me in the presence of Thy radiance, Thou annointeth my head with Vitamin D, My brain turneth over.. Yea, though I walk through the valley of the shadow of depression, I will fear no evil for Thou, Sun, art with me, Thy light and thy warmth they comfort me. Surely goodness and mercy shall follow me all the days of my life And I will dwell in the Land of the Sun forever.. Post Partum Depression (PPD).The birth of a new baby should be one of the very happiest times for a womanand her family. The sound of a happy baby should bring tears of joy to amothers eyes, and a bond that can never be broken. However, in about 10percent of births things go wrong, and shortly after the mother gives birth,the blues [Post Partum Depression (PPD)]set in. Sometimes these blues aremild and short term and sometimes they become so severe that they become apsychosis. Postpartumdepression (PPD) can be much more severe than clinical depression inother women. Many psychiatric symptoms found in people that later developclinical depression are also found in women destined to develop PPD. Magnesiumdepletion of the mother by the fetus is very likely the main cause of PPD.Magnesium is extremely important for the synthesis of steroids such as theandrogenic and estrogenic hormones as well as cortisone-like hormones. It iswell known that the fetus and placenta absorb enormous amounts of nutrients(especially magnesium) from the mother, which is a major stressor for themother. Magnesiumand hormones are not plentiful in the delivered placenta, but are inthe newborn. Stressdepletes magnesium and can result in depression, whether the person is apostpartum woman or not, or an infant. In the infant, Sudden Infant Death Syndrome(SIDS) remains a leading cause of death during the first year, and isnow suspected as being a severe magnesium deficiency. Similarly, sudden deathin adults is believed to be caused by severe magnesium deficiency. Magnesium iseffective in rapidly curing depression and preventing sudden death heartattacks in adults. Each of the stressors shown above (physical, trauma,psychological, environmental and metabolic) clearly apply to pregnancyand childbirth. It is very difficult to see how they would not have an adverseeffect on maternal magnesium reserves unless the mother has allowed herself toeat those fattening foods rich in magnesium or has supplemented her diet withmagnesium. If postpartum depression is nothing but clinical depression due tomagnesium deficits induced by stress (including financial), poor diet, or both,magnesium supplements in the dosage of 200 mg magnesium per meal should easilyprevent and cure this horrible condition without side effects. In hospitals,magnesium sulfate IV is given to women to prevent seizures ofeclampsia. Magnesium sulfate exposure to fetuses reduced by 90 percentthe incidence of cerebralpalsy and mental retardation in very low birth weight babies duringtheir first five years of life. It is difficult for me to understand how theseexpensive hospital treatments are more justified than inexpensive dietarymagnesium supplementation during pregnancy to prevent these complications andpost partum depression (PPD). There are numerous Post Partum Depression (PPD)support pages on the Internet, and this is my favorite. At least fourwomen having had extreme problems with PPD in several previous pregnancies usedmagnesium in response to this essay to essentially prevent post partumdepression (PPD). In PPD, endocrine problems also usually need to be addressed,but they are secondary to magnesium. Reported first in 2001, low magnesium ininfants causes weak muscles which promotes SuddenInfant Death (SIDS), which is believed to be associated with maternalPPD. Sports Over Trainingoccurs when stressful and repetitive training depletes the individualsmagnesium stores. See original medical research here. Sports and physicalfitness training requires stress, not mental stress, but adaptive body stress.Athletes must put their bodies under correct amounts of stress to increasephysical capabilities. Where the stress loads are appropriate then theathletess performance will improve, but if the stress loads are excessive thena state of "over-training" will occur as magnesium stores aredepleted. Symptoms indicating over exertion can be classified in the followingway: Movement co-ordination symptoms: Increased incidence of disturbances in movement (the re-appearance of faults that seemed to have been overcome, cramp, inhibitions, insecurity). Disturbances in rhythm and flow of movement. Lack of ability to concentrate. Reduced power of differentiation and correction. Condition symptoms: Diminished powers of endurance, strength, speed. Increase in recovery time, loss of sparkle Competitive Qualities. Reduced readiness for action, fear of competition, giving-up in face of difficult situations, especially at the finish. Confusion in competition, departure from usual tactics. Susceptibility to demoralizing influences before and during competition. Increasing tendency to abandon the struggle (quit sports). Psychological symptoms: Increased irritability, obstinacy, tendency to hysteria, grumbling, defiance, increased quarrelsomeness, avoidance of contact with coach and colleagues, over-sensitivity to criticism, or increasing indolence, poor incentive, dullness, hallucination, anxiety, depression, melancholy, insecurity, burn-out. These symptoms also occur in military recruit training and during the stress ofmilitary conflicts. Lack of sufficient magnesium in the diets of our athletesand soldiers limits our nations ability to compete. Consider this fact. Duringthe invasion of Afghanistan to route al Qaeda, we sent many tons of raw wheat,rich in magnesium, to prevent starvation in natives, yet we sent our troops toAfghanistan with Meals-Ready-To-Eat, which is only average (450 mgmagnesium/day) in magnesium. Mamas send your soldiers some magnesium! Post TraumaticStress Disorder (PTSD), a disorder that occurs in and after military orpolice conflict, terrorism, such as the attack on the World Trade Center andPentagon, major accidents, school yard bullying and other stressful events,meet all of the symptomatic and stressor criteria for being a magnesiumdeficiency disorder due to excess stress and should also respond to magnesiumtaurate treatment benefiting "structure or function" of thebody or "well-being". Spasmophilia,in France and to a lesser extent in Germany and Hungary, has a similar meaningto manic depression in the United States. The main symptoms are anxietyneurosis, panic attacks, permanent muscle spasms, asthma and other respiratoryproblems and prickly sensations in hands and arms and sometimes face.Spasmophilia is also a condition of very low energy, mental fogginess, vaguedepression and unexplained but extremely persistent muscle spasms. The Frenchstudies on spasmophilia however indicate that it is not only magnesium butcalcium that is deficient as well as potassium, phosphorus and vitamin D. Ifyou read French (or will click on Google.com translation), you will find thatconsiderable research has been done on "SPASMOPHILIE"which is well worth our time to examine closely due to the closeness of theseFrench and U.S. afflictions and their treatment with magnesium. Since lowmagnesium will cause low calcium, potassium and phosphorus in the serum,perhaps all these people need is more magnesium and some sunlight. Succeed! Depression is not a psychosis! Attention Deficit HyperactiveDisorder (ADHD) In 1921, Dr. Paul G. Weston, MDfirst showed that magnesium sulfate administered intravenously relaxed peoplehaving excited emotional states, the very definition of ADHD. All of thepatients were noisy, talkative, very restless and resistant. Many weredepressed, some were manic, and some had other mental disorders. Out of 250doses, 220 of these treatments resulted in relaxing the patients and they sleptfor 4 to 6 hours upon IV administration of magnesium sulfate. Dr. Westonsfindings, published in Volume 1 of the American Journal ofPsychiatry was completely ignored by the American PsychiatricAssociation, setting the stage for magnesium deficiency as cause of AttentionDeficit Hyperactive Disorder in children and adults to remain ignored for thefollowing 80 years. However, there were hints along the way that magnesium washelpful in treating hyperactivity. For example biochemist, Dr. Adell Davissuggested in her 1970 book LetsEast right to Keep Fit, that magnesium was beneficial in treatinghyperactivity in children and adults. In 1987, Nelsonet al. reported neonatal hyperexcitability in full term babies wasrelated to significantly lower than normal serum magnesium. In 1993 Nizankowska-Blazfound low level of magnesium in blood serum in 24 out of 247 children inPoland. Twenty-one of the 24 children had neurotic reactions or concentrationdisturbances. In 1994 Kozielecet al. found significant magnesium, zinc, copper, iron and calciumdeficits in plasma, erythrocytes, urine and hair in 50 Polish children agedfrom 4 to 13 years with hyperactivity. The average concentration of all traceelements was lower compared with the healthy children control group and theyfound that it was absolutely necessary to supplement trace elements in childrenwith hyperactivity for them to regain emotional control. In a follow up study Kozielecet al. introduced their 1997 article with the comment: "A positiveinfluence of magnesium in the prevention and treatment of hyperactivity inchildren is more and more frequently raised in the medical literature".They continued in their original research article with the astonishing findingthat in 116 children (94 boys and 20 girls), aged 9-12 years, with recognizedADHD, magnesium deficiency was found in 95 per cent of those examined.Following up their observations, Kozielecet al. treated ADHD children with and without magnesium withspectacular results. Their research comprised 50 hyperactive children, aged7-12 years, who fulfilled DSM IV criteria for ADHD syndrome, with recognizeddeficiency of magnesium in the blood and in hair. In the period of 6 monthsthose examined regularly took magnesium preparations in a dosage of about 200mg/day. Thirty of those examined with ADHD showed coexisting disorders specificto developmental age, and 20 of them showed disruptive behavior. The controlgroup consisted of 25 children with ADHD and magnesium deficiency, who weretreated in the standard way (without magnesium supplements). Fifteen members ofthis group showed coexisting disorders specific for developmental age, and 10members showed disruptive behavior. Hyperactivity was assessed with the aid ofpsychometric scales: the Conners Rating Scale for Parents and Teachers,Wenders Scale of Behavior and the Quotient of Development to Freedom fromDistractibility. In the group of children given 6 months of magnesiumsupplementation, independently of other mental disorders coexisting withhyperactivity, an increase in magnesium contents in hair and a significantdecrease of hyperactivity of those examined was achieved, compared to theirclinical state before supplementation and compared to the control group whichhad not been treated with magnesium. Later in 1998, one of the Polish scientists, Dr.Starobrat-Hermelin followed up with analysis of more minerals in ADHD.He studied the deficiencies of magnesium, copper, zinc, calcium and iron inblood that occurred among 116 ADHD hyperactive children (DSM IV criteria) andcompared them with blood from healthy children. Although some disruptivechildren had slightly higher zinc serum concentrations, magnesium concentrationswere lower in children with ADHD than in healthy children. Supplementing withmagnesium alone, all minerals tested increased compared to ADHD children notgiven magnesium supplements. Accompanying the rise in mineral serumconcentration there was a decrease of hyperactivity in the group of childrentreated with magnesium. Among the children given standard treatment (withoutmagnesium) hyperactivity intensified. Consequently, this Polish study providesstrong clinical evidence that there is a need for magnesium supplementation inADHD children irrespectively of other mental disorders. Do you think Western children with ADHD will receive proper magnesiumsupplementation to decrease their hyperactivity? If you are a skeptic, you areprobably right. Instead, they will be given "upper" drugs; one suchdrug is the amphetamine dextroamphetaminewhich has the unique property of elevating magnesium in serum and significantlyreducing the calcium to magnesium ratio. On the other hand, psychiatric drugslike Psychoverlanand Pemoline,and are being used to treat ADHA which contain magnesium. Mothers! watch outfor the pharmaceutical drug peddlers! Ritalin, a standard for ADHA is nowbelieved to causecancer. Clearly the FDA does not know what it is doing. Insomniais a major problem in the treatment of ADHD with stimulants. I wonder if too much sugar and notenough magnesium causes insomnia of ADHD? wouldnt hurt to try. Let meknow! Succeed! Depression is not a psychosis! Age Activated Attention DeficitDisorder (AAADD) Age Activated Attention Deficit Disorder (AAADD) is a newly described mentalcondition currently being experimentally treated using very aggressive andexpensive psychiatric medications by extremely accomplished psychiatrists. Thesymptoms are complex and usually totally bewildering. AAADD affects mostly men inWestern society over 40 years of age, and causes great economic hardship andinjury if not carefully treated. AAADD usually affects men for the rest oftheir lives if not successfully and promptly treated. AAADD is usually firstidentified by spouses of men so afflicted. Rather than to try to describe theextremely subjective signs and symptoms of this most difficult and challengingmental illness, I will recount a story in a letter to me from a newly diagnosedAAADD victim. > Dear George, They have finally found a diagnosis for my condition. I have recently been diagnosed with A.A.A.D.D. - Age Activated Attention Deficit Disorder... This is how it goes on a typical Saturday morning: I decide to wash the car; I start toward the garage and notice the mail on the table. OK, Im going to wash the car, but first Im going to go through the mail. I lay the car keys down on the desk, discard the junk mail and I notice the trash can is full. OK, Ill just put the bills on my desk and take the trash can out, but since Im going to be near the mailbox anyway, Ill pay these few bills first. Now, where is my checkbook? Oops, theres only one check left. My extra checks are in my desk. Oh, theres the coke I was drinking. Im going to look for those checks, but first I need to put my coke further away from the computer, or maybe Ill pop it into the fridge to keep it cold for a while. I head towards the kitchen and my potted flowers catch my eye, they need some water. I set the coke on the counter and, uh oh! There are my glasses. I was looking for them all morning! Id better put them away first. I fill a container with water and head for the flower pots - - Aaaaaagh! Someone left the TV remote in the kitchen. We will never think to look in the kitchen tonight when we want to watch television so Id better put it back in the family room where it belongs. I splash some water into the flower pots, but most of it goes onto the floor. Better clean this up. I head back down the hall to the bathroom, the remote still in my hand. I set the remote on the toilet seat so I can pull an old bath towel down from the shelf. As I walk back down the hall Im trying to figure out what it was I was going to do. NOON: The car isnt washed, the bills are unpaid, the coke is sitting on the kitchen counter, the flowers are half watered, there is a water stain on the floor, the checkbook still only has one check in it and I cant seem to find my car keys or the TV remote. There is only one obvious solution: I need to settle down and check my mail. WOW, look at those cool photos my sister sent, and those jokes from my nephew. Oh, what the heck, Ill just make me a TO-DO list and tend to the other chores later, maybe tomorrow. Now where did I put my pen?" Your friend, Tom Toya, Either a very specialized and expensive psychiatric treatment is required, orvictims can just take magnesium taurate. Actually, You have just been spoofed!And I hope you find this anecdote humorous. There is no psychiatric illnesscalled AAADD, but dont the symptoms seem all too real? Who knows, maybe it isa real disorder treatable benefiting the "structure orfunction" of the body or "well-being" by magnesium taurate. Succeed! Depression is not a psychosis! Falling In Love "Falling in love" has a special sound to it. It is the topic ofcountless songs, movies, and TV shows. Countless diaries record love affairsand the despair that goes with unrequited love and lost, dying love affairs.Take another look at the words "falling in love". It seems that"falling" is the operative word. Why dont we say "rising"in love with a sweet heart? Jesus wanted us to "rise in love" of theFather. Why would we want to "fall" into anything? Would you want tofall into a pit (of despair)? Wouldnt love be better if love (not animalpassion) caused us to "rise" in love? Ideally, love does raise ourspirits, and a few times in a persons life, "falling in love" leadsto marriage, and our well-loved, and usually spoiled progeny. After all, loveis what makes the world go around. The "dark side" of love is not as simple to explore, and we mustreconsider "falling in love" as a "hyperexcitatory" or"hyperemotional" state which is treatable beneficial to the"structure or function" of the body or the "well-being"with magnesium taurate. When love-gone-wrong turns to depression (as itdoes for so many love-sick teenagers and desperate-for-love folks of any age),think magnesium - not Prozac. When that special loved one makes you so anxiousyou could scream, think magnesium - not Valium. When that special loved one irritatesyou to the point you want to kill the bastard, think magnesium - not a gun. Unrequited love is a saddening affair which no one will doubt. There is littlethat one can do to fight a shadow, and one cant run from a shadow either. Youare stuck and in deep stress and turmoil and in need of magnesium and time. Weoften turn to music in our darkest love-less moments. In my experience withmusic, there is one album (F L O A T I NG I N T O T H E N I G HT ) that reallygoes all the way in exploring the dark underside of love-gone-wrong. The lyricsare by D a v i d L y n c h, and the music is by A n g e l o B a d al m e n t i. The compositions are sung with great reverence, style and beautyby J u l e e C r u i s e. Some of you will recognize songs in thisalbum as being from D a v i d L y n c hs ethereal TV program of theearly 90s "T w i n P e a k s". If you are love-struck,and just want to listen to someone who seems to feels as bad as you, I stronglysuggest curling up with a magnesium bottle and listening to her songs oflove-gone-wrong. I might add that in the early 90s, I was so struck by hermusic that I spent hours each day listening to this single album. I nearlydrove my wife crazy. Please buy her album, it is a world-class treasure worthyof any lovers music collection. Succeed! Depression is not a psychosis! Corporate Murder and Our Food In her year 2000 book, "CRAZYMAKERS - How the Food Industry is Destroying Our Brains and Harming OurChildren", published by JeremyP. Tarcher/Putman, New York, NY; nutritionist Carol Simontacchi, PhD,writes, "It (magnesium) is used to regulate receptor sites forneurotransmitters, and is active in the hippocampus, the emotional center ofthe body." This book explores our dietary habits and exposes Americanfood manufacturers as compromising our foods and leading us into malnutritionand its corollary mental and physical disorders. Most importantly, it explainswhat we can do about it. In the tradition of Dr. Rachel Carsons landmark work SilentSpring, she takes a hard, shattering look at how the pseudo foods beingpromoted today, from infant formulas to supposedly health-conscious packagedmeals can, in fact, physically erode our brains. The"Grain Drain", displayed without comment (Readers Digest,March 2003, page 180) says much. This data adopted from the Harvard Heart Letteris a strong indictment of grain refiners. The nutrients taken out of wheat arethe same nutrients that when deficient cause depression and many healthproblems in the West. Who is to blame for much of human health misery? I votefor the grain refiners. But wait! They listen to the consumer, and the consumer(totally mindless when it comes to nutrition and health) wants a fine whitebread that has the consistency of velvet. What is the difference between breadand cake? Sugar. We know we shouldnt eat cake, but there is little benefitleft in bread too. We have only ourselves to blame, because we are listening toour taste buds rather than common sense. Why hasnt public policy addressedthis horrible circumstance? Lobbyists? Consideringthe raw wheat used to make our bread, magnesium content is high and is about 4times higher than calcium; yet, commercial breads, cakes and cookies that weserve our families are nearly devoid of these precious minerals - to preservefreshness and shelf life! Scientists around 1930 studying comparativecancer rates in Egypt and the West noted that Egyptian breads contained naturalamounts of magnesium while Western processed bread contained very little. Theynoted that the cancer rate in Egypt was ten percent that of the West at thattime. Is there something to be learned here? If we dont start paying attentionto what we eat, will we perish? I wish they would worry more about"preserving" our lives rather than "preserving" shelf life.Do you know of any magnesium fortified foods? I dont. Succeed! Depression is not a psychosis! Constipation Means To Us... NATIONAL INSTITUTES OFHEALTH CONSENSUS DEVELOPMENT CONFERENCE STATEMENT - OPTIMAL CALCIUM INTAKE:Normally, constipation is associated with too much water being removed by thecolon. However, we (people toxic on calcium) must also consider the role ofcalcium overdose in constipation. The above official United States governmentreport describes optimal calcium intake for various age and status groups ofpeople mentioning the word "magnesium" once, stating that"magnesium did not affect calcium absorption or excretionsignificantly". Of particular note, "...Gastrointestinal side effectsof calcium supplements have been observed, usually at relatively high dosages.A variable effect on the incidence of constipation has been reported incontrolled studies of calcium supplements. The calcium ion stimulates gastrinsecretion and gastric acid secretion, which can produce a reboundhyperacidity when calcium carbonate is used as an antacid. These side effectsshould not be major problems with a modest increase in calcium intake, howeverpractices that might encourage total calcium intake to approach or exceed 2,000mg/day seem more likely to produce adverse effects and should be monitoredclosely." Two thousand milligrams of calcium per day is the upper safe limit? Wow! What adisaster! If calcium were a newly discovered drug (perhaps dietary supplementsof calcium should be so considered), it would be described as having anextremely low threshold for toxicity and would likely be a prescription drug!Apparently because of the emphasis on calcium by the NIH, the current rageamong other government food scientists, food product manufacturers, dietarysupplement manufacturers and dairy industry is to routinely push our totalintake of calcium over the 2,000 mg/day limit. I believe that abuse of this"consensus report" is rapidly deteriorating mental and cardiologichealth, and is greatly increasing violence inWestern society. Where is the NIH consensus report on magnesium? It doesnt exist, yet magnesiumis key to mental health as discussed in this essay. With the NIH overemphasison calcium, many depressed people have exceeded the 2,000-mg/day limit and arebecoming very constipated. With little magnesium (relative to calcium in theintestinal tract) and resultant inability to regulate water and maintain a softstool, constipation results. The amount of calcium required to produceconstipation is related to the dietary intake of magnesium required to loosenthe stool. If an imbalance between calcium and magnesium exists, with calciumbeing high and magnesium being low, then constipation occurs at much lowerintake of calcium than the 2,000-mg/day limit. What to do? Taking moremagnesium dietary supplements to balance the intestinal calcium/magnesium ionratio greatly reduces constipation. Although too much magnesium can lead todiarrhea, just as too much calcium can lead to constipation, magnesium taurateis readily absorbed into the blood and is not as likely to produce diarrhea asare other forms of magnesium. Magnesium oxide, hydroxide and carbonate,stearate are either very poorly absorbed or not absorbed at all, never raiseblood levels, never show biological utility, and consequently the oxides andhydroxides end up in the large intestines and colon attracting large amounts ofwater producing diarrhea. The stearate just passes through with no effects,either beneficial or negative. Obviously, foods high in magnesium and foodshigh in water-soluble fiber are preferred to refined foods and cheese toprevent constipation. As far as we are concerned in the treatment benefiting"structure or function" of the body or the "well-being"of depression (and other magnesium deficiency disorders especially cardiologicproblems) using magnesium taurate, constipation certainly can mean that we arenot getting enough magnesium relative to calcium in our diets. In many casesof depression and related disorders, our diets are much too high in calcium andmust be greatly lowered deleting most foods high in calciumfrom our diets in order to benefit from magnesium in our treatment. Apparently,We have become toxic with calcium. Dont believe me? Check your calcium intake from this handy calcium intake calculator.If you have a calcium intake near or over 1,000 mg/day, and have littlemagnesium intake, you may very well have a dietary imbalance of calcium andmagnesium complete with all the attendant sequela. Be honest! Here is an interesting tid-bit. We know magnesium oxide is a health foodsupplement (absorbedonly by 4% and is totally useless) and that magnesium hydroxide is astrong laxative (not absorbed into blood at all), but what about calcium oxide and calciumhydroxide? Have you ever seen calcium oxide or calcium hydroxide in ahealth food or grocery store? No! You never have! Why do I know that? Becausecalcium oxide and calcium hydroxide are extremely caustic and are commonly usedto dissolve flesh from bones in animal rendering plants and to disinfectouthouse waste. You think calcium is always healthy and good for you? These twocompounds of calcium will kill you very quickly and painfully as they dissolveyour mouth, throat, esophagus and stomach. Succeed! Depression is not a psychosis! Violence and Mayhem Violence is not simply a magnesium deficiency problem for people; but is acomplex societal problem involving as principal factors magnesium and calcium /magnesium dietary intake ratios, medical conditions resulting in or from lossof magnesium, drugs (both legal and illegal), stress, and our moral, culturaland religious training and beliefs. That magnesium deficiency as a cause ofviolence has not been directly recognized by medicine or science can easily beascertained by doing a PubMedsearch for the words "magnesium" and "violence". ZERO meaningfulentries result. However,work at the Institute of Public Health, Iaşi, Romania, is making inroadsthrough a recentlypublished study of low intracellular magnesium and psychologicalfeatures (attention, memory, intelligence, psyhoticism, neuroticism andextraversion). This study shows profound differences in intracellular magnesiumlevels and these parameters between children growing up in an orphanage andchildren growing up at home. The adverse effect of low intracellular magnesiumon these parameters often translates into "bad behavior" in schoolage children, which includes violence and mayhem. People having problems with irritability, anxiety, depression, ADHD, mania,hypo-mania, bi-polar disorder, hyper-excitability and hyper-emotionality areall very closely tied to the latent potential for violence, outright violenceand mayhem, either self-inflicted or inflicted upon other people or property.This is so well known, that I feel no pressure to cite volumes of medical literature.It is common knowledge. Why has there been no medical research on the role ofmagnesium deficit in violence and violence prevention? Perhaps we are unwillingto accept the notion that the foods we eat affect our minds, and would ratheraccept the notion that we have diseases curable by powerful psychiatric drugs.Really? Who does the research on mental diseases? Nutritionists? No.Psychiatrists and pharmaceutical drug companies? Yes. Is there more money to bemade in drugs or nutrients? Where does the money flow? No need for me to answerthese questions lest one consider me to be a "conspiracy theorist".Are physicians well trained in nutrition? Not many. There is a void in theeducation of people we trust to take care of us when we are ill that, to me,borders on criminality. The way I see magnesium in violence and mayhem prevention is potentially as agentle injected sedativefor use by emergency medical service people, paramedics and other emergencymedical professionals treating an agitated, potentially violent individual; andin nature and nutrition, as a natural gate or valve in the brain synapses thatregulates influx of calcium into postsynaptic calcium channels from presynapticneurons in parts of the brain that are involved in mood and behavior such asthe hippocampus. With inadequate magnesium or calcium toxicity, this functionbecomes altered and irritability, anxiety, depression, ADHD, mania, hypo-mania,bi-polar disorder, hyper-excitability and hyper-emotionality, and perhaps somepsychoses, result. If an exogenously or endogenously agitated person has weakmoral, cultural and/or religious training and beliefs, manifesting as fewbehavioral inhibitions, and inadequate magnesium to inhibit his emoted actions,violence may result. As a society, we need to strengthen our moral, culturaland religious training and beliefs, and we need much more magnesium in ourdiets to inhibit our actions during times of emotional distress - often broughton by calcium and/or glutamate toxicity. Nearly ninety percent of all suicides result from depression (except forMiddle-Eastern crazed religious zealots who actually believe they are doinggood), which results from severe magnesium depletion due to stress or dietaryinadequacies or excessive losses of magnesium through the urine. Manic behavioris nearly always outwardly directed, and a manic person may commit violenceupon another person or damage or destroy property during emotional outbursts.Hyperexcitability, and hyperemotionality in persons with mania, hypo-mania,by-polar disorder and ADHD have been shown in this essay to be nearly alwayscontrollable with IV magnesium treatment, and are responsive to dietarymagnesium supplementation. PaulMason makes a case for violence prevention through amagnesium/serotonin connection. Although society has a major role to play inpreventing violence, proper magnesium nutrition plays an equal, if not superiorrole - which remains generally unrecognized, even though animal research shows increased aggressive behaviorin magnesium deprived test animals. Remember, the NIH reports that even modestmagnesium deficits cause irritability, and such does not impair ones strengthor ability to mount aggressive action and commit violence. I wonder if animalswould become aggressive and violent if they were deprived of magnesium richwhole grains by feeding them refined bread, cheese and pizzas? I wonder ifviolence-prone Palestinians and Arabs get enough magnesium in their diets? What about Andrea Yeats violence to her children? Andrea is the Houston,Texas, lady that had a long history of severe depression and suicidal tendenciesand severe postpartum depression after the births of her most recent two of herfive children. Magnesium is fairly well known to be depleted by pregnancies. Ibelieve depletion of magnesium by multiple childbirth and inadequate magnesiumnutrition causes postpartum depression for reasons explained here and throughoutthis essay generally. Is it possible that Andrea suffered medical malpracticeby not being treated for severe magnesium deficiency brought on by her multiplepregnancies? Was she tested for magnesium deficiency? At least seven women inresponse to this essay through 2003 having had progressively worse problemswith PPD in several previous pregnancies used magnesium taurate to essentially preventbenefit "structure or function" of the body or"well-being" PPD after their most recent deliveries. Is itpossible that Andrea was so suicidal that in her psychotic mind committingsuicide (a side effect of grave magnesium depletion) was an insufficientpunishment to herself? If she were to commit suicide, who would have taken careof her children? Was she so delusional she felt that killing her children wasthe only way to save them from eternal damnation of a violent and unholy worldif she committed suicide? Doesnt it appear reasonable that she had to kill herchildren before she killed herself? And that in a single moment of sanityafterwards called 911 instead? Can magnesium deficiency be so severe that noteven suicide is sufficient? What do you eat? Do your eating habits promote hyperexcitability or depressionfrom excess calcium? Succeed! Depression is not a psychosis! Good Fats and Deadly Fats We have been told all our lives that cholesterol is dangerous and that we mustlimit our cholesterol intake. Based upon new evidence, we must revise ourthinking about cholesterol a little to take into consideration that very lowcholesterol will kill a person faster than high cholesterol. Generally, thenormal fasting concentration of total cholesterol is 160 to 200 mg/dL in serum.Many cardiologists and pharmaceutical drug pushers argue that the range shouldbe lower. However, in a series of recent clinical research reports since 1992,people with low cholesterol (and some with low Omega-3 Essential Fatty Acids)were prone to suicide, violence, rage, depression, and violent impulsivebehavior often resulting in a death. This research is so new and so different fromconventional wisdom, that it has not made its way into mainstream psychiatry.Psychiatrists may see people with this condition on occasion but they rarely,if ever, see this as a serious mental health problem. Search PubMedfor "low cholesterol" "suicide", "violence","death" and "depression" for some of the most excitingpsychiatric research every conducted. I doubt that no one should purposefullyraise his or her cholesterol intake if it is in the normal range; but if it issignificantly lower than 160 mg/dL, consideration of its cause is mandatory andis extremely urgent. Consequently, we must reconsider the use of cholesterol-lowering drugs. Statin drugs,or "HMG-CoA reductase inhibitors", are the most widely prescribedclass of blood cholesterol-lowering drug. The top sellers as of this writingare atorvastatin (Lipitor), which currently is given to 4 million persons inthe US, and simvastatin (Zocor), and pravastatin (Pravachol). Other statinsinclude fluvastatin (Lescol), lovastatin (Mevacor), and cerivastatin (Baycol).These drugs have been shown to markedly reduce heart attacks, and to reduce strokesas well as "peripheral arterial disease" (a disease that consists ofclogging of the arteries to the legs). Many studies have confirmed reductionin heart attacks and strokes. However, studies in monkeys, performed by Dr. JayKaplan at Bowman Gray Medical School, have shown that lowering cholesterol inmonkeys makes them more aggressive; and also lowers activity of the brainchemical serotonin. Low serotonin activity is known to relate to suicide anddepression in people; and to increased risk-taking behaviors in monkeys. Ifthese drugs pass through the blood-brain barrier, they would interfere withvital brain cholesterol, the main biochemical component of the brain. We mustremember that there is vastly more cholesterol in the brain than in any otherorgan, tissue or blood. The brain has its own support cells that make braincholesterol. In fact, about 60% of the brain (in all species) is cholesterol.Cholesterol belongs in the brain and forms critical brain structures. Upsettingthat balance - either too much or too little - is harmful to mental health. Toomuch and one risks strokes and Alzheimers disease; and too little, one risksmood disorders, violence and suicide. The unproven hypothesis thatcholesterol-lowering drugs save lives needs to be carefully examined to see ifdeaths from violence and suicide equals or exceeds the number of lives savedfrom heart attacks. To my way of thinking, one should not take statin drugsmore than absolutely necessary to maintain cholesterol in the normal range, andonly after trying to correct cholesterol levels using Omega-3 EFAs, taurine andmagnesium. One of the tragedies of our time is over emphasis of eliminatingfats from our diets. Physicians, especially female physicians, have bought intothe erroneous theory of avoiding fats, and they consequently have the highestsuicide rates of any profession. What about supplementing Omega-3Essential Fatty Acids (EFAs) to treat depression too? Scientists longwondered why Eskimos and Japanese fishermen had so little heart disease eventhough their fat intake was extremely high. After much research, scientistfound that oils from raw cold water fish contained a heart protective oil knownas Omega-3 Essential Fatty Acid (EFA), which is present in great excess overOmega-6 and Omega-9 EFAs. Watch this 2.5 MEG Windows movieshowing the extreme danger of Omega-3 EFA collection. I wanted the very finestof Omega-3 EFAs, so I went to Alaska and went ice fishing for cold water fish,but see what happened to me! You wont believe it! On the other hand, in theWestern diet the ratio of Omega 3 EFA to Omega-6 and Omega-9 is reversed, with6 and 9 being present in great excess over 3; consequently our extensivecardiologic problems - highly solvable with increased dietary Omega-3 EFAs andmagnesium. Unfortunately, Omega-3 EFAs and magnesium are not used much incardiology in favor of expensive statins. Flax seed oilalso has Omega-3 Essential Fatty Acids in great abundance to the Omega-6 and -9oils, and is being used to improve cardiac and mental health. Although Omega-3EFA has had some use in treating depression, it has not been exciting as anantidepressant when not taken with magnesium. When taken with magnesiumtaurate, the results are often said to be spectacular, particularly in treatingbenefiting "structure or function" of the body or the"well-being" anxiety. Do I take Omega-3 EFAs? Yes, and I willfrom now on. How much do I take? I took 2 teaspoon of fresh (refrigerated) flaxseed oil with each meal for several months, but discontinued it due to severeside effects (benign but strong cardiac arrhythmias caused by flaxseedsability to greatly raise blood sugar). Never take more than the product labelrecommends, because too much Omega-3 EFA oils will solubilize cell membranes,raise blood sugars to dangerouslevels, and generally cause much worse problems than they solve.Elevated blood sugars may be fine for Eskimos trying to keep from freezing todeath, but they are a definite no-no for people in a temperate climate. Whatdoes the right amount of Omega-3 EFA do for me? Besides making it easier totake large amounts of magnesium without diarrhea, it lifted my mood andprevented anxiety even on the dreariest or meanest day. Does Omega-3 EFA haveother benefits to the brain? In England, large doses, enough to solubilize cellmembranes, has been used to cure schizophrenia. Mahatma Gandhionce said, "Wherever flaxseed becomes a regular food item among people,there will be better health." Overdosing flaxseed oil can backfireresulting in cardiac arrhythmias (probably from allergicreactions) and other side effects, of which, Harvard Medical Schoolwriters offer considerable comment and warning here.Of particular interest to men is the high content of phytoestrogens in flaxseedoil. Feminization due to excessive consumption of plant estrogens is just aslikely, or more likely, from flaxseed as it is from excessive soy beanconsumption. Because I am male and have an allergy to flaxseed, I now avoidflaxseed oil and use cod liver oil as a source of Omega-3 EFAs. However, Ibelieve that the effects of taurine inpreventing cardiovascular disease are at least as important or more importantthan Omega-3 EFAs; and that eating eggs for Omega-3 EFAs and Ocean fish, andespecially conch, blood clams, inkfish, clams, shell fish, crabs, prawns pighearts, and chicken legs (but not chicken breasts), for taurine is the safestway to obtain these benefits. Lets not forget lecithin. Lecithin is a lipid that is required by every singlecell in your body and is an important source of inositol and phosphate. Inositolhas been reported to be effective in treating central nervous system disorderssuch as depression, Alzheimers disease, panic disorder, andobsessive-compulsive disorder. Neurotransmitters such as serotonin and acetylcholinein the brain depend on inositolto function properly. The cell membranes in the body are composed largely oflecithin and water. These membranes handle the flow of nutrients in and out ofthe cell. The protective sheaths around your brain are also made of lecithin.Muscles and nerve cells also use lecithin. Should everyone take lecithin orinositol? Not necessarily. Although, inositol has therapeutic effects in thespectrum of illness responsive to serotonin selective re-uptake inhibitors,including depression, panic and OCD, it may not be beneficial,in patients with schizophrenia. Bad fats? Practically everything that is man made or processed, especiallyhydrogenated fats, margarine, and trans fatty acids. More on essential fattyacids and their role in preventing cancer are here. Succeed! Depression is not a psychosis! Lithium / Magnesium Interactions I want to know more about lithium / magnesium interactions. We know thatmagnesium is primarily an intracellular metal. We have seen above that lithiumpulls magnesium out of cells and into the blood serum. Yet, we see low levelsof serum magnesium in suicidally depressed patients. High dose IV magnesiumterminated treatment-resistant mania. We also see that about 40 percent oflithium treated manic-depressive patients have a relapse. There is clearly moreto the lithium / magnesium interaction story than we currently know. Questionsto be answered include: Which cells, organelle, enzymes and proteins are being drained of their magnesium by lithium and what are the binding constants applicable? Which brain cells, organelle, enzymes and proteins are up taking the freed magnesium and what are the binding constants applicable? Is the beneficial effect of dietary supplements of magnesium substituting for the blood magnesium raising effect of lithium? Is low or falling magnesium blood content a marker for mania or depression in otherwise well people having a history of mania and/or depression? In relapse during lithium treatment, do the relapsing patients have low blood serum levels of magnesium? Are the side effects of lithium treatment the result of its intracellular magnesium depleting function? Should magnesium be used to treat mania and/or depression before drugs are tried, or should it be a treatment of last resort, or should it be used as an adjuvant to other drug treatment? Are neurotransmitter fluxes and functions optimized in magnesium responsive mania and depression? Is lithium an inappropriate treatment in cases where magnesium supplementation is effective in eliminating mania and/or depression? YES!!!!! Is raising blood magnesium concentrations all that is necessary to prevent and terminate mania and depression, and prevent relapses of mania or depression? NO!!! It must be maintained! Is the effect of magnesium relevant to only a subset of people with depression, or a subset of people with manic depression; or is it universally relevant? In 1998, lithiums action in regulating both mania and depression was ascribedto its ability to regulateglutamate levels in the brain. As reported in the July 7 Proceedingsof the National Academy of Sciences, the researchers found that in micebrains, lithium exerts a push/pull effect on the neurotransmitter glutamate,eventually causing it to level off in a stable zone where it can control bothextremes. I dont know if the effect of lithium in human brains is the same asin mice brains, but I do know that I felt much better taking magnesium than lithium.Regardless, both magnesium and lithium control the ups and downs of bi-polarillness. Why? It is simple, the final stage of the recycling process of IP3involves inositol monophosphate, which controls the levels of IP3 and controlsmood swings. The enzyme needs two atoms of magnesium to function, an elementwhich is much more similar to lithium than calcium (the diagonal relationship).Computer modeling shows that lithium binds tothe second magnesium site, especially if phosphate is present. Thisstops the enzyme working. Thus IP3 is not broken down. The lithium only workson an overactive enzyme, one that breaks down IP3 too quickly causing moodswings. Why not give magnesium? Seems pretty stupid (and criminal?) to me togive lithium when magnesium is being called for by the brain. Succeed! Depression is not a psychosis! Biochemistry Magnesium is a critical element in 350+ biochemical reactions and enzymes inthe human body, and many of them are brain biochemicals. Magnesium is thesecond-most abundant intracellular cation and; overall, the fourth-mostabundant cation. Almost all enzymatic processes using phosphorus as an energysource require magnesium for activation. Magnesium is involved in nearly everyaspect of biochemical metabolism [eg, deoxyribonucleic acid (DNA) and proteinsynthesis, glycolysis, oxidative phosphorylation]. Nearly all enzymes involvedin phosphorus reactions (eg, adenosine triphosphatase [ATPase]) requiremagnesium for activation. Magnesium serves as a molecular stabilizer ofribonucleic acid (RNA), DNA, and ribosomes. Because magnesium is bound to ATPinside the cell, shifts in intracellular magnesium concentration may helpregulate cellular bioenergetics such as mitochondrial respiration. Extracellularly,magnesium ions block neurosynaptic transmission by interfering with the releaseof acetylcholine. Magnesium ions also may interfere with the release ofcatecholamines from the adrenal medulla. Magnesium has been proposed as anendogenous endocrine modulator of the catecholamine component of thephysiologic stress response, a main thrust of this essay. Recent research inFrance and several other European countries gives clues concerning the rolemagnesium plays in the transmission of hormones (such as insulin, thyroid,estrogen, testosterone, DHEA, etc.), neurotransmitters (such as dopamine,catecholamines, serotonin, GABA, etc.), and minerals and mineral electrolytes.Consequently, its deficiency and a linkage to depression should be expected. Succeed! Depression is not a psychosis! Age of Onset is Getting Lower Perhaps the best testimony of the effect of reducing the amount of magnesium inour diets by eating depleted wheat products (refined grain products) is foundin this figure. It is from page 386 of Psychopharmacologyby Jerrold S. Meyer and Linda F. Quenzer, copyright 2005 by Sinauer Associates,a psychology text book. Only 1 percent of Americans born before 1905 developeddepression before they were 75 years old, while 6 percent of Americans born in1955 developed depression by the time they were 25 years old. I say thisincrease in depression is caused by our increased use of refined (depleted)wheat. The grain refiners are taking care of Big Pharma! The authors onlymention magnesium in passing once, and have essentially ignored theextraordinary breadth of the role of magnesium in psychopharmacology, insuringthat the secret will remain for at least another generation of future neuropsychologists. Yes, America has the best health care system in the worldbecause we need it, and low magnesium is the driving force. Magnesium in Water Natural magnesium in water (magnesium carbonate dissolved in CO2-richwater) is suggested to be more bio-available than magnesium in food or pill,and is suggested to offer greater cardio-protection. However, these mineralwaters are not commercially available at your grocery store at this time. A citizens petition forthe voluntary fortification of beverages has been submitted to the FDA, but wasrejected. Scientists have advocated increasing hard water consumption to gainminerals such as magnesium. This idea has merit in depression for two reasons.We would increase our magnesium intake from drinking hard water. Second, thefeeling that we associate as being "hungry" is often a disguiseddesire for water - thirst! Consequently, we get our water from the foods weeat, along with the calories associated with unhealthy, demoralizing weightgain - if we eat the wrong foods. See this link for more on eatingdisorders. Magnesium-rich mineral waters are available in most of the world, and a fewsources are available in the United States. For example, NOAHs Spring Water inModesto, CA is made from Adobe Springs water and contains 110 mg/litermagnesium. Ditto Hi-O-Silver oxygenated water, also bottled in Modesto by 7-Up.Coca-Cola has a brand new beverage that is probably the best-for-you beverageever marketed by a major soft drink company. It is loaded with magnesiumsulfate and potassium chloride, so loaded one can clearly taste the metals.What is it called? Dasani!!!!Ah heck. I rechecked Dasani and it no longer tastes metallic. I guess they tookthe magnesium out of it. Genesee Valley water has a high magnesium content andis bottled in Michigan. Here is a listof the magnesium content of some of the waters bottled in the US. For acomplete list of hundreds of magnesium-rich waters bottled throughout theworld, click here. Succeed! Depression is not a psychosis! Cocaine / Magnesium Magnesium given to mice was shown to increase the potency of a single dose ofcocaine and a magnesium-deficient diet reduced its potency. On the other hand,with chronic cocaine use magnesium countered cocaines effects,according to these medicalresearchers. Perhaps cocaine abuse in people could be controlled withhigh dose magnesium. Perhaps the cocaine-like property of magnesium is theproperty that elevates mood in depression refractory to antidepressants. Exposure of cocaine HCl (10-9 to 10-7 molar)resulted in significant, rapid (1 minute) loss of intracellular free magnesiumions (Mg2+ ion) incultured canine cerebral vascular smooth muscle cells; these reductions(12-25%) in Mg2+ ion were reversible upon exposure to normal,Mg2+ ion-containing physiological salt solution. These findings help to provide arational basis for why cocaine can result in cerebrovasospasm, and hemorrhagicstroke. Here are examples for ratsand dogs.Otherresearchers have found data that suggests that magnesium salts might beuseful agents in the treatment of cocaine-induced intoxication and preventionof brain damage. Considerable additional evidence for benefit of"magnesium" in "cocaine" toxicity in laboratory research isnow available in this PubMedsearch. Succeed! Depression is not a psychosis! Mitral Valve Prolapse Along with depression, mitral valve prolapse is often found in young thinwomen. Among the curable disorders associated with the heart that are magnesiumdeficiencies are mitralvalve prolapse according to this Russian study. These young ladieswatch their weight and avoid fattening foods which coincidentally are the maindietary source of magnesium. Additional on this relationship can be found by searchingPubMedusing "mitral valve prolapse" and "magnesium" as keywords.Also see Magnesium Deficiencyin the Pathogenesis of Mitral Valve Prolapse and Mitral Valve Prolapse.The way in which magnesium affects mitral valve prolapse relates to leaky heartvalves having hardened tissue, possibly from tiny calcium deposits in the valves.Just like a hardened rubber gasket in a water valve can leak, a supple newrubber gasket doesnt leak. In the same way, magnesium makes tissues suppler.Consequently, proper magnesium nutrition eliminates the incidence of mitralvalve prolapse and repleating magnesium to proper levels reverses it after ayear of treatment as shown in the Russian study. Clinicalsymptoms of mitral valve prolapse are related to hypomagnesemia andattenuated by magnesium supplementation. After 5 weeks of magnesium therapy,the mean number of symptoms per patient decreased from 10.4 +/- 2.1 to 5.6 +/-2.5 (p dyspnea, arrhythmias, and anxiety was observed. Increased noradrenalinexcretion before and after magnesium was seen in 63% and 17% of patients,respectively (p (catecholamines or stress hormones) was significantly diminished aftermagnesium. It is concluded that many patients with heavily symptomatic MVP havelow serum magnesium, and supplementation of this ion leads to improvement inmost symptoms along with a decrease in catecholamine excretion. Interestingly, in 2001, when this paragraph was first written, there were 4,000articles about magnesiumand cardiology on the Internet, with nearly all showing benefit to theheart and cardiovascular system, usually through management of calcium andrelaxation of cardiac muscles. Today, in October of 2004, there are 504,000articles. People are listening to scientists and speaking out! No more will thepharmaceutical drug pushers monopolize thisissue! Succeed! Depression is not a psychosis! Other Nutrients Important inDepression Potassium is very important in magnesium metabolism. Few of us get enoughpotassium unless we frequently eat bananas, tomatoes and potatoes anduse MortonsSalt Substitute, which contains nearly pure potassium chloride [withoutcardiac protective iodide (iodine)], which helps balance our pre-salted foodshigh content of sodium chloride. These minerals, sodium and potassium, shouldbe consumed in the same meal because they work together to determine the bodyselectrolyte balance, which regulates water levels. Eating a lot of salty(sodium chloride) food disrupts this balance and harmfully lowers magnesiumconcentrations. This not only produces high blood pressure, but also affectsneurotransmitter levels, producing depression and PMS. In addition, the misuseof diuretics, or "water pills," can lead to potassium deficiency,which in turn can manifest itself as depression. InMildred S. Seelig, MD, MPH and Andrea Rosanoff, PhDs new book Themagnesium Factor on page 61 is a fascinating table that shows exactlywhy we have problems with increased stress and stress-induced depression(treatment resistant depression) from a mineral perspective. Although she isaddressing the enormous increase in incidence of hypertension and cardiacproblems in the later part of the twentieth century compared to 1900, the dataalso explains the enormous increase in emotional problems. > Changes in Average Mineral Intake, Mineral Ratios in the Diet and Hypertension This table from "The magnesium Factor" shows the change in the average mineral intake and balances that have occurred among the American population between 1900 and 2000. Note the great rise in sodium and the decline in both magnesium and potassium. Indicator Year 1900 Year 2000 Average daily sodium intake 200 mg 5,000 (25 times higher than in 1900) Average daily potassium intake 6000 mg 2,000 mg (2/3 lower than in 1900) Average daily magnesium intake 400 mg 250-300 mg (2/3 lower than in 1900 Average sodium:potassium ratio 1:30 2.5:1 (75 times higher) Average sodium:magnesium ratio 1:2 25:1 (50 times higher) Incidence of hypertension and stress induced illnesses Low High Clearly,this horrific change in dietary intake of these critical minerals affects ouremotional and mental health. We are eating too few vegetables and much too muchprocessed foods and salt and not enough magnesium to keep us in good health.Although this essay relates primarily to the relatively unknown value ofmagnesium in treating depression and related disorders, it is not the onlynutrient important in treating depression. Here are more interesting and highlyrevealing tid-bits on dietand emotions. Other naturalremedies for depression include supplements of the amino acidsL-tyrosine, D,L-phenylalanine, L-tryptophan, Vitamin B6 (pyridoxine), Folicacid, Vitamin B12, taurine, CoQ10 and Vitamin C. Here is a link for kidsconcerning nutrientdeficiencies and mental health, which adults can learn from also. This is VitaRoyalsMineral Wheel. It represents the competitive interactions between differentmetals during absorption in the intestines. Many metals interfere withabsorption of others. Dietary bias in favor of one mineral, say magnesium, willaffect absorption of several other minerals, mainly calcium and manganese. Whatwe eat and drink can influence our magnesium balance, but not to the extentthat is caused by large supplements of minerals. It should be noted thatmagnesium and calcium share a common route of absorption in the intestinaltract and appear to have a mutually suppressive effect; thus, if calcium intake(or dairy intake) is unusually high, calcium will be absorbed in preference tomagnesium. Also, excessive doses of vitamin D (perhaps explaining SAD insummer), calcium supplements and glucose can cause renal magnesium loss.Excessive calcium, animal fat, saturated fats, manganese and phosphorus decreaseintestinal absorption. Alcohol, caffeine, sugar, potassium and sodium increaseurinary excretion. Folic acid may increase the metabolic need for magnesium.High protein and excessive sugar (glucose) in the diet definitely requireincreased magnesium intake, sometimes to the upper limit possible. High doseriboflavin may increase the risk of magnesium deficiency. Vitamin B6 increasescell membrane transfer and utilization of magnesium, and is very helpful,indispensable, in retaining magnesium. People like me that have craved milk, cheese and ice cream products fromchildhood usually have an allergy (eventually becoming a maladaption) to milkproducts. The maladaption stage may wait 20 years, even 30, before setting in.Then come headaches, depression, cramps, and diarrhea. The milk allergy neverreally left. If eliminating milk from the diet helps depression symptoms, byall means dont drink milk - none! Since cheese is a potent source of calcium,competition with magnesium for intestinal binding sites may result in reducedmagnesium absorption helping to cause depression symptoms. Scientists believethat lactose malabsorption from milk and dairy products may interfere with theavailability of L-tryptophanand the synthesis of serotonin. Both substances are anti-depressants,suggesting food supplements of L-tryptophan and lactase enzyme (Lactaid®) indepressed lactose intolerant people. Succeed! Depression is not a psychosis! Tryptophan, 5-HTP and Serotonin No discussion of depression can be complete without considering the role ofclassical antidepressants including tryptophan, 5-hydroxytryptophan (5-HTP),selective serotonin reuptake inhibitors, (SSRIs), tricyclic antidepressants,atypical antidepressants, and monoamine oxidase inhibitors (MAOIs). Examples ofSSRIs include Fluoxetine (Prozac®,Sarafem®), sertraline(Zoloft®), and paroxetine(Paxil®). Other antidepressants include tricyclic antidepressants suchas amitriptyline(Elavil®), imipramine(Tofranil®) and, nortriptyline(Pamelor®), atypical antidepressants including trazodone (Desyrel®),nefazodone(Serzone®), buproprion (Wellbutrin® andMAOIs including phenelzine(Nardil®), and tranylcypromine(Parnate®). A much more comprehensive list of psychiatric drugs andtheir pharmacology is here.Many of these drugs (Prozac, Zoloft, Luvox, Celexa, Lexapro, Effexor,Wellbutrin, Serzone and Remeron) have been linked to worsened depression andmake many people, particularly children and teenagers suicidal. Read more aboutthese side effects and the findings by the Food And Drug Administration dated March 10,2004. These are some of the most financially lucrative drugs on themarket and are taken by many millions of people. The theory, extremely briefly,is that depressives are deficient in certain biochemicals. Serotonin (5-HT)is selectively targeted by SSRIs, while tricyclic antidepressants affect theuptake of norepinephrine, serotonin and dopamine to different degrees. Atypicalantidepressants have actions not well understood. MAOIs increase the levels ofnorepinephrine, serotonin and dopamine by inhibiting an enzyme that inactivatesthem. These drugs will "fix our biochemistry" and make us feelbetter. Have you tried these drugs? Did you experience horrible side effects? Idid. Fix my biochemistry? HA! Really! Did your doctor tell you that you wouldneed to be on these drugs for at least a month before they worked? I wonder howmany people would get better in the same time without them? Hereis a wonderful Opus cartoon titled "Let the SunshineIn". It is in five frames, and you will need to pull down to seeeach of the frames. Opus makes fun of the horrible state of affairs of drugside effects, and is vital to our appreciation of the problems attendant withtaking pharmaceutical drugs. The side effects are often worse than the originalcomplaint. There must be a better way to market drugs. I call for a nationalhealth care policy of "no sales" if there are any side effects worsethan the problem being addressed. Watch out for the "Big NosePimples!". Haveyou wondered where these drugs came from? Who thought them up? Well, you are inreal luck now, because I now offer you the chance of a lifetime to read areport by one of the Nobel Laureates who came up with the SSRIs, Dr. AvidCarlson. He writes in 1999 "AHalf-Century of Neurotransmitter Research: Impact on Neurology andPsychiatry". This is first class reading! BUT! The AmericanPsychological Association says that the main effect of these drugs isone of a placebo effect. Manypeople have serious sideeffects (see this registry) while taking these drugs; and in the caseof Prozac, and other chemically similar drugs, have had strongsuicidal tendencies after withdrawal from them. There is an onlinepetition addressed to the Office of the Surgeon General of the United States;The Department of Health & Human Services; The Federal Bureau ofInvestigations and The Justice Department currently signed by more then 10,000petitioners demanding a Grand Jury Investigation into serious misconductconcerning Prozac on the part of Eli Lilly, the drugs manufacturer.Specifically, the petitioners assert that Eli Lilly has known of and engaged inthe suppression of the truth concerning the drugs ability to cause suicide andsuicidal ideation. They assert that Eli Lilly has knowingly and fraudulentlyconcealed facts surrounding its drugs deadly side effects. Documented findingsof cover-ups supporting their demand include, but are not limited to, thefollowing: See petition here.This tendency toward suicide upon stopping these drugs causes many people tocontinue taking them after their need for them has passed. Probably all of thesedrugs have side effects in some people and many have serious side effects uponwithdrawal. Search Google.com for yourantidepressant and add the terms "withdrawal" and "sideeffects" to see what risk you are exposed to upon withdrawal. Many ofthese drugs have class-action lawsuits filed against them. In your Google.com search, add the words"class-action" or "class action" to find these lawsuits.Use quotation marks in your search to multi-word terms to find the exact term.Strangely, perhaps to the cynic, predictably few physicians counseltheir patients about the risks associated with withdrawal. Perhaps a greatlyover-simplified explanation for "withdrawal" side effects is that by useof these drugs, brain chemicals are provided from a bottle, not from thebrains own biochemical factory. This results in shifts in brain biochemicalproduction that over time can not be quickly altered by the brain upon a suddenwithdrawal. Consequently, the symptoms return and often they return with avengeance. In a saner world, many of these drugs would probably be consideredthe ultimate in crazy, illegal, and addictive drugs, having side effects as badas illegal street drugs. TheProzac Truth web site containsmuch information about issues related to Prozac and other SSRIs. The site alsodescribes the side effects of SSRIs and other antidepressants and psychiatricmedication, and recommends nutritional supplements and other strategies tocounteract side effects and assist with withdrawal. One finding mentioned isthat low levels of glutathione (an amino acid consisting of cysteine, glutamicacid and glycine), which is manufactured only inside cells, causes many of theside effects of classical antidepressants and that nutritional support mighthelp. Magnesium deficiency is rampant in depression, and scientists haverecently found that low intracellular magnesium causes low intracellularglutathione (explorethis google.com search). Consequently, if you are taking a SSRI andwant to minimize side effects and accelerate recovery, magnesium supplementationwill likely be very beneficial. Remember that clinical drug tests are paid for by the pharmaceutical drugpushers, who tweak their trials design for the best possible results. Untilrecently, only the most favorable findings got published, because thosejournals dependent on the drug pushers for funding (advertising). The drugs areapproved for marketing by government regulators, whose salaries are mostlyfinanced by the subjects of their evaluations - since pharmaceutical companiespay to have their products vetted. The regulators dont stay at government jobslong, since their real fortunes are with the pharmaceutical drug pushers, andthey rotate in and out of the FDA and other governmental regulatory agenciesbut always go to Big Pharma for their real "reward". The medicinesare then prescribed by doctors routinely courted with pharma gifts - from freepens to family skiing holidays - meant to persuade them to change theirprescribing habits. They bombard you with advertisements for their poisons onTV, so that you will ask your doctor for them. They have programmed you tobehave the way they want, just like they program the regulators. Recently, Ilearned that to expedite drug testing, somecompanies use tribal African natives in medical research experiments,people who are well outside of the regulatory authorities in the United States. However, the Internet has helped consumers turn the tables on thepharmaceutical drug pushers. Pages like the one you are reading and many othersdedicated to exposing the toxic effects of antidepressants have finally made animpact on the pharmacartels. This is coming to light especially now with theSeroxat problem. Drug injury has been worrying experts for decades. But afterthe thalidomide tragedies of the 1950s, the subject failed to catch fire forpoliticians and the public until the recent Seroxat antidepressant controversy.Last month, that debate made headlines when Britains GlaxoSmithKline, theworlds second-largest pharma, denied any wrongdoing, but agreed to pay $2.5million to settle a lawsuit filed by the State of New York accusing it of fraudfor concealing evidence of its antidepressantSeroxats potential for harming children, while doing them nomeasurable good. As time goes on, the public using the Internet will show theevil of these companies, and demand that both the benefits and harm found inevery clinical trial, not just the good stuff, be made public. Each of the above drugs affect serotonin levels, either exclusively or alongwith other brain biochemicals. The best wayto address true serotonin deficiency may not be through these potentiallydangerous drugs. Rather, the answer may lie in precursors to serotonin such astryptophan and 5-HTP and repletion of magnesium. Low magnesium has beenimplicated in low serotonin,resulting in depression and sometimes violence. Clearly, from this essay,magnesium is involved in mood and mental health. The effect of magnesium supplementationcan be much more rapid on depression than any psychiatric drug, tryptophan or5-HTP taken without magnesium, suggesting the need for increased magnesium, andperhaps one or more of these drugs or natural precursors to serotonin. However,remember that the effects of most antidepressants is one of a placeboeffect. Unfortunately,most people seeking help from physicians for depression also need to seek theirhelp for other illnesses too. Seems like when the "brain goes south"that everything else does too. Consequently, other drugs are also used bydepressives, some of which deplete magnesium and other critical nutrients.Although there is very little published information about the depletion ofnutrients by SSRIs, there is much known about the depletion of nutrients byother drugs. Drugs that are known to deplete magnesium include: Premarin(conjugated estrogens), Lasix (furosemide), Hydrochlorothiazide, Triamterene/HCTZ,Prednisone, Ortho Tri-Cyclen (norgestimate/ethinyl estradiol), Prempro(conjugated estrogens/medroxyprogesterone) and Flovent (fluticasone). CatherineCreel has listed the nutrient depletion effects of the 45 most commonlyprescribed drugs in the MedicineGarden web site. If you are taking any prescription or non-prescriptiondrugs, you need to review her page and supplement accordingly. Catherinealarmingly points out: "Drugs that are used primarily to address mentalstatus show a distinct pattern of a lack of nutrient depletion studies. Peoplewho take any of these drugs long term usually develop digestion problems,thyroid problems, high cholesterol, cardiovascular disease, autoimmunedisorders, kidney and liver weakness and/or disease, loss of energy andinterests, and have a higher incidence of cancers than those who do not takeany of these." Consequently, they often resort to use of additional drugsto treat those side effects. You have been warned! Tryptophane is an amino acid found in our food. It was a very popular naturalantidepressant several decades ago, but was prohibited by the FDAfor sale for a few years in the United States until 1994 when the DSHEA, was passed.Tryptophane was prohibited because a single batch was improperly made in Japanusing genetically engineered bacteria, causing eosinophilia-myalgia syndrome(EMS) in about 1500 cases, including at least 37 known deaths. Many thoughtthat the real reason was to protect the lucrative pharmaceutical drug trade.While tryptophan prohibition may have been needless, it had one unforeseenbenefit. It allowed researchers to focus on 5-HTP; which, it turns out, may bemuch better than tryptophan ever was for treating disorders that appear to berelated to a deficiency of serotonin in the brain including depression. Examples of thetryptophan levels in a few foods are listed below. FOOD SERVING SIZE TRYPTOPHAN (mg) Pineapple, fresh 1 cup 8 Pineapple, juice-packed 1 cup 13 Yogurt, plain 1 cup 51 Turkey, light meat, roasted 3.5 oz 340 Turkey, dark meat, roasted 3.5 oz 325 Chicken, light meat, roasted 3.5 oz 361 Chicken, dark meat, roasted 3.5 oz 303 Banana 1 medium 14 Almonds, dry roasted 1 oz 83 Cashews, dry roasted 1 oz 67 Peanuts, dry roasted 1 oz 64 Sunflower seeds, dry roasted 1 oz 84 5-hydroxytryptophan (5-HTP) is an amino acid. Commercial 5-HTP isnot a manufactured chemical but is found in high concentrations in a herb,namely the dark brown seed of Griffoniasimplicifolia, an African plant. Consequently, 5-HTP is less likelyto have a potential for manufacturing mistakes and is generally considered tobe safe when used in low doses. Our bodies make 5-HTP from tryptophan andconvert it to serotonin, an important brain chemical. Tryptophan is anessential amino acid found in turkey, chicken, milk, potatoes, pumpkin,sunflower seeds, turnip, collard greens and seaweed. With the exception ofseaweed, dont these foods sound like foods we eat to celebrate our AmericanThanksgiving Day? Tryptophan and 5-HTP dietary supplements help raise serotoninlevels in the brain, which produce a positive effect on sleep, mood, anxiety,aggression, appetite, temperature, sexual behavior, and pain sensation. 5-HTPhas been neglected by many psychiatrists and mental health scientists despitetantalizing hints in the scientific literature that it may have profoundeffects on a variety of extremely common and often debilitating ailments suchas depression. Perhaps this neglect comes from its lack of patentability andprofitability. 5-HTP has no national advertising campaigns in its support. TheNIH, FDA and other governmental agencies are more concerned about the publicfinding its efficacy and using it over the more thoroughly researchedpharmaceutical company manufactured antidepressants. It is the same old story,nature knows best, but Big Pharma has the big bucks. Yet, clinical trialsshow that it is more effective, has fewer side effects than severalprescription antidepressants, and takes about the same amount of time asprescription antidepressants to become effective. 5-HTP is generally bettertolerated than its SSRI counterparts, such as Prozac®. The following chartcompares the rate of side effects between 5-HTP and SSRIs. Side Effect % of Patients Experiencing Side Effect 5-HTP SSRIs Nausea Headache Nervousness Insomnia Anxiety Drowsiness Diarrhea Tremor Dry mouth Sweating Dizziness Constipation Vision Changes 9 5 2.5 2.5 2.5 7 2.5 0 7 2.5 5 5 0 23 20 16 17 14 11 12 11 12 9 7 5.5 4 Source: 5-HTPThe Natural Way to Overcome Depression, Obesity, and Insomnia byMichael Murray, N.D. In magnesium replete people, 5-HTP can work overnight; again stronglyimplicating low magnesium as the cause of slow or limited response to prescriptionand herbal anti-depressants. There are many over-the-counter sources of 5-HTP.Nearly every health food store has it and absolutely no prescription isrequired. Here is a link to sources of 5-HTPon the Internet. Does 5-HTP have other beneficial effects? Yes. 5-HTP may, infact, be treating a much broader disease termed "serotonin deficiencysyndrome." This syndrome may manifest in any of a variety of forms, includingdepression, anxiety, sleeplessness, aggressiveness, agitation,obsessive-compulsive traits, migraines, and other common behavioral disorders;in short, everything that is currently being treated with expensive SSRIstoday. Is 5-HTP a threat to major pharmaceutical company income and stockprices? Yes. Should we expect some kind of pharmaceutical company organizedattack on 5-HTP? YES, but DSHEA will block those attacks to a large degree - atleast until Congress can be convinced to revise DSHEA by implementation of CODEX. At leastthe public will have a chance to be involved in that political process. Whatare the side effects andcontraindications? Large excesses of serotonin in the peripheralcirculation can cause cardiovascular disease and other adverse effects. Alcoholdoes not mix well with 5-HTP. See full list of side effects andcontraindications here.Too much 5-HTP in the diet could potentially result in too much serotonin inthe peripheral circulation causing cardiovascular disease. The literaturesuggests that 5-HTP can be safely used as a nutritional supplement at a dosageof up to 100 milligrams (mg) per day. Some authorities maintain that muchlarger dosages can be consumed without adverse effects. Some also suggest that5-HTP, especially in larger doses should be used with the prescription drug"carbidopa" to prevent the cardiovascular problem. There is a warningabout too much vitamin B-6 with 5-HTP. All in all, 5-HTP seems much safer andmore effective, particularly when used with magnesium, than prescription drugs.Perhaps the most startlingstory of results with 5-HTP occurred in the treatment of a man that hadnot been able to sleep for 4 months, possibly due to a viral infection of thebrain. 5-HTP given in large doses (2 to 12 grams) first improved the patientscondition dramatically. After 5-HTP withdrawal there was a gradual worsening ofthe patients condition. 5-HTP therapy was again attempted but was thenineffective in reversing the symptoms and the patient died after 11 months ofsickness. Other precautions are at 5-HTPDanger, and include warnings about use in lactation, pregnancy, usewith other antidepressants, and other health conditions. Other general is here.Of concern to me is what side effects can be expected upon withdrawal from5-HTP? I found none, but strongly suspect there could be some. I base thisreasoning on the fact that all of the serotonin enhancing agents, when suddenlydiscontinued present the brain with a major change in serotonin levels, achange to which the brain can not suddenly adapt. Abuse of any of these agentscan cause serotonin toxicity. Butwhat does the AmericanPsychological Association say about these antidepressants? Well, to putit politely they think that their main effects are placebo effects. I tend to agree,but less kindly because I found them harmful. In the abstract of their report,they found that the mean effect sizes for changes in depression were calculatedfor 2,318 patients who had been randomly assigned to either antidepressantmedication or placebo in 19 double-blind clinical trials. As a proportion ofthe drug response, the placebo response was constant across different types ofmedication (75%), and the correlation between placebo effect and drug effectwas 0.90 (extremely high correlation). Their data indicated that virtually allof the variation in drug effect size was due to the placebo characteristics ofthe studies. The effect size for active medications that are not regarded to beantidepressants was as large as that for those classified as antidepressants,and in both cases, the inactive placebos produced improvement that was 75% ofthe effect of the active drug. Their data raised the possibility that theapparent drug effect (25% of the drug response) is actually an active placeboeffect. Examination of pre-post effect sizes among depressed individualsassigned to no-treatment or wait-list control groups suggested thatapproximately one quarter of the drug response is due to the administration ofan active medication, one half is a placebo effect, and the remaining quarteris due to other nonspecific factors. Succeed! Depression is not a psychosis! DHEA DHEA,dehydroepiandrosterone, is the most prevalent and one of the mostessential hormones in human health. Unfortunately, most Americans lose 80-90%of their optimal DHEA between ages 30 and 80. According to Dr. Norman Shealy,MD, PhD, every known human illness is associated with both a magnesiumdeficiency and low levels of the hormone DHEA. DHEA is the health and youthhormone in humans. If DHEA is low, magnesium is low. They go together. Even a10% increase in magnesium and DHEA serum levels is associated with a 48%decrease in death from cardiovascular disease and a 36% decrease in mortalityfrom all causes. Humans have the only body that has significant levels of DHEA.Low levels of both DHEA and magnesium characterize most human illnesses. Aconnection between these essential chemicals appears to be basic to theunderstanding of health, wellness and the restoring and maintaining of youth.Low levels of DHEA are found in women up to nine years BEFORE development ofbreast cancer. And men may have low DHEA levels for four or more years prior todevelopment of prostate cancer There is a long list of DHEA/magnesiumdeficiency symptoms. They are anxiety, hyperactivity, confusion, depression,diarrhea or constipation, faintness, fatigue, hyperventilation, lack ofcoordination, insomnia, intestinal problems, muscle cramps, muscle tightness,pain, poor memory, seizures, tinnitus and vertigo; and these are just thesymptoms! All of which are associated with depression, and all of which aremarkers for worsened future health without intervention with magnesium. Major diseases associated with DHEA and magnesium deficiencies are: anginapectoris, arrhythmia, asthma, atherosclerosis, Attention Deficit Disorder(ADHD), auricular fibrillation, bulimia, cancer, cardiomyopathy, chronicfatigue, chronic bronchitis, congestive heart failure, cirrhosis, depression,diabetes, emphysema, gall bladder infections and stones, hearing loss, heartattack, high cholesterol, hypertension, hypoglycemia, chronic infection (viraland bacterial) intermittent claudication (leg calf pain), kidney stones,migraine, mitral-valve prolapse, osteoporosis, panic attacks, PMS (premenstrualsyndrome), benign prostate hypertrophy, PVCs and strokes. In no illness isDHEA /magnesium deficiency more prevalent than myocardial infarction (acuteheart attack). On average, patients given magnesium intravenously have a 70%greater survival rate. Can we take DHEA supplements? Yes, but in people that dont need DHEA, anincrease in cancer risk occurs. Dr. Shealy believes that raising magnesiumconcentration inside cells will also raise DHEA concentrations and is muchsafer than taking DHEA supplements. Research PubMedand Google.comfor "DHEA" and "magnesium". Interestingly, there are only20 items on PubMed citing "magnesium" and "DHEA", over 7000on DHEA, and over 63,000 on magnesium. Why, if these arguments are correct, aretheir so few on the combination? Succeed! Depression is not a psychosis! Veterinary Uses and AnimalResearch We compete one of our horses in national competitions. Loss of appetite,exhaustion, poor condition, excessive excitability (ever try to ride an excitedhorse?), nervousness (this condition can get the rider killed), sweating,muscular tremor, cillosis, muscle strains, cramps, tetanies, and cardiovasculardisturbances are prevented using horsemagnesium supplements. Also, taurine (two heaping tablespoons with eachof four meals per day) benefits horses similarly, making the hottest, wildestthoroughbred horses docile and well mannered even for the dressage arena, eventhough their energy levels increase. It seems to me that veterinary medicine isfar ahead of psychiatric medicine! Theantidepressant and anti-anxiety properties of magnesium can be shown inresearch animals subjected to severe stress. For example, Poleszaka, Szewczykb,Kedzierskaa, Wlaz, Pilcb, Nowak in Poland in 2003 showed: "Theantidepressant- and anxiolytic-like effects of magnesium, anN-methyl-D-aspartate (NMDA) glutamate receptor inhibitor, were studied in miceusing the forced swim test and elevated plus-maze test, respectively. The dosesof 20 and 30 mg Mg/kg, reduced immobility time in the forced swim test exertingantidepressant-like activity. In the elevated plus-maze test, magnesium at thesame doses produced anxiolytic-like effect. The doses of magnesium active inboth tests did not affect locomotor activity. To evaluate the tolerance tothese effects, we also performed experiments on the following acute/chronicmagnesium treatment schedule: chronic saline and saline challenge at 0.5 hbefore behavioral experiments or serum magnesium determination (S + S), chronicsaline and magnesium challenge (S + Mg), chronic magnesium and saline challenge(Mg + S), chronic magnesium and magnesium challenge (Mg + Mg). Theantidepressant- and anxiolytic-like effect of magnesium was demonstrated ingroups treated acutely and chronically with magnesium (Mg + Mg), but not in theMg+ S group. Moreover, these effects seem to be connected with at least 58%increase in serum magnesium concentration. The results indicate that magnesium inducesthe antidepressant- and anxiolytic-like effects without tolerance to theseactivities, which suggests a potential antidepressant and anxiolytic activityof magnesium in these disorders in humans." See their complete article here. Yep, those guysare right! Succeed! Depression is not a psychosis! Our Prognosis and Caveats The diagnosis of manic depression (bi-polar disorder) or depression isdevastating. What is the prognosis for those of us that are responsive tomagnesium and not pharmaceutical drugs? Will we be permanently cured ofour condition using magnesium supplements? My prediction is PROBABLY NOT, BUT VERY,VERY CLOSE TO BEING CURED. I base that point of view on personal observationsafter using magnesium for over three years (with a few lapses), and the manyreports of others that have used magnesium successfully to rapidly terminatetheir symptoms and who have later gone off magnesium. The results of going offmagnesium are similar to a manic depressive or depressive going off his/herprescription "meds". The symptoms come back, albeit much more rapidlythan with drugs having a long half-life. And, they go away equally fast uponresumption of magnesium. What does this mean? Perhaps we have developed apermanent condition, which is best described as an inability to properlyprocess, manage, store, assimilate, utilize and metabolize magnesium from our diet.However, judiciously adding boron and Omega-3 EFAs, chromium and vanadium,and cutting out high glycemic index foods and cutting out calcium and glutamatesand especially eliminating Candida Albicans infections seem to greatly improveour ability to use magnesium and the combination appears much more curative.Reducing stress in our lives to lower our adrenalin levels (one of themagnesium depleting agents) that is normal to the "fight or flight"reaction is also helpful. Remember, stress (disabling emotion) builds up whenwe cannot fight or flight, and magnesium acts like an "aspirin for theemotions". Lowering catecholamine levels (several magnesium depleting stress hormonesreleased during stress) should reduce the loss of magnesium and preventdepression. However, those of us with a history of depression react to catecholaminedepleting agents very differently than people who have never beendepressed. We become more depressed, not better, while people having never beendepressed have little or no response to catecholamine depletion. Worse,catecholamine depletion adverselyaffects the immune system and makes us vulnerable to infectiousdiseases and cancer. We are different - WE NEED MORE MAGNESIUM THAN OTHERPEOPLE. I hope people will respect our civil rights and not discriminate inemployment or insurance by using the catecholamine test to test for a historyof depression. On the other hand, our prognosis is vastly better than before. Not only doesour depression disappear and remain absent while taking the right amount ofmagnesium, but we gain many other well known benefits from elevated magnesiumintake. Some other benefits of magnesium repletion in aging were brieflycompiled by the NovartisFoundation for Gerontology. The foundation shows that magnesium will: Prevent hardening of the arteries (arteriosclerosis) Prevent strokes and heart attacks Reduce your blood pressure Lower your cholesterol and triglyceride levels Correct heart arrhythmias Stop acute asthma attacks Decrease your insulin needs if you have diabetes and can cure diabetes Prevent kidney stones Treat Crohns disease Treat noise-induced hearing loss Improve your vision if you have glaucoma Reduce cramps, irritability, fatigue, depression, and water retention associated with menstruation Prevent serious complications of pregnancy, such as preeclampsia and eclampsia Restore your normal energy level Improve your sleep Reduce anxiety and depression Reduce the effects of stress Succeed! Depression is not a psychosis!Codex Alimentarius:Will It Kill Us or Save Us? Codex Alimentarius(Codex) is something that we will need to consider. Will it kill us orsave us? I dont know, but we all need to be aware of the issue. Codex is aworld-wide set of rules that are supposed to "harmonize" all foodsand food substances throughout the world as part of the World TradeOrganization treaty. The United States signed the treaty under thebelief that it would not harm the health and well being of United Statescitizens, and that it would be beneficial to Americans and trade generally. Onepart of these rules is "harmonization" of the content of vitamin,mineral, amino acid, and herbal supplements. The net effect of Codex concerningthese nutrients is that the total amounts of these food supplements wouldlikely be greatly reduced or eliminated. In other words, if you wanted to godown to your neighborhood health food store and buy a bottle of 500 mg VitaminC tablets, sorry, the Codex would not allow sales of more than about 30 mgtablets at about the same price that we now pay for the 500 mg tablets. Otherexamples include total disallowance of many commercial vitamin, mineral, aminoacid and herbal products. I have heard that about 90% of products currentlyavailable in health food stores would be abolished, and heavy criminal fines,and jail terms, would be established. Five-hundred mg Vitamin C tablets,magnesium supplements and many other seemingly innocuous products andcombinations would be as illegal as sale of heroin or ephedra. Only approvednutrient supplements and dosages would be available over the counter. Thetheory being that some of these dosages and combinations are "hazardous"and that the rules are needed to preserve the public health world-wide, whichmakes as much sense as restricting computers to no more than a 286microprocessor, because the Pentium class processors are "nationalsecurity" risks. However, really dangerous and clearly harmful foodsupplements like table salt (sodium chloride), excesses of which withoutsufficient potassium to balance it, cause some heart attacks, and sugar(sucrose), excesses of which causes sugar diabetes (curable with large doses ofmagnesium), and refined flour (essentially gluten), nutrient depleted forshelf-life reasons, would not be regulated because they are part of ourestablishment "culture". Implementation of Codex would bypass current United Stateslaws, and eliminate important choices for Americans and othersworld-wide primarily to benefit the international pharmaceutical drug pushers. Internationalpharmaceutical companies have been totally unable to commercialize nutrients astreatments for diseases, mainly because of the wide availability of low pricenutritional supplements. Even though pharmaceutical drug pushers are as awareof their health benefits as any well-trained nutritionist, they can not competefinancially with the dietary supplement industry. There have been FDA movementsto prevent people and companies from telling the truth about the value ofnutrients in treating diseases and preserving health. Even though a very famousSupreme Court case (Pearsonvs. Shalala) forced the FDA to back off (sort-of), the FDA has tried tomake statements that "nutrients cure, prevent or treat diseases"illegal. This is in deference to the will of pharmaceutical drug companies.Foods and nutrients prevent and cure many "diseases" that are reallynutrient deficiencies in disguise. For example, severe depression can beconsidered the "symptom" of magnesium wasting disease, which is thereal illness. Without some of the to-be-disallowed nutrients, there exists theclear possibility that people will die, become or remain ill with no legal wayto recover. The idea of individual differences in nutrient demands of people,well established by many nutritionist and other scientists, would be thrown outthe door. Onthe other hand, food producers, mainly grain refiners and the entire industrythat relies on grains to produce everything from Twinkies to waffles seemsunable and unwilling to fortify flour and flour products with the minerals,vitamins and amino acids removed from these food products during refining.Consequently, many nutrient deficiency diseases have occurred and are greatlyaffecting the quality of life and shortening the life span of people who relyupon these low-cost "foods". Perhaps they are not"low-cost" at all when their adverse impacts on health areconsidered. Now,enter Codex rules! Consider the actual effect of these rules. The foodproducers get to prepare nutrient depleted foods, which results in manynutrient deficiency diseases, while the pharmaceutical drug pushers will haveno competition to sell nutrients to treat the diseases that would otherwise beprevented if people could retain access to truly wholesome foods andsupplements. The pharmaceutical drug pushers would prepare expensive(half-billion dollar) New Drug Applications and work with the FDA and othernational drug regulatory groups to prepare those same nutrients that will betaken away from us, and then sell them back to us at about 10 to 50 times theprice that they are available to us now. Ireally wonder if this is what Congress and the Administration had in mind whenthey approved the World Trade Organization treaty. I think the grain and foodrefiners and the pharmaceutical drug companies are really pulling a fast oneover America and the Western world. What will happen if, overnight, all of thenutrients that we have come to rely upon are taken away from us? Well, John C.Hammell, Legislative Advocate and founder of the International Advocates forHealth Freedom seems to believe that it will cause a grass roots rebellion.Indeed, they actively seekrebellion world-wide. See their extensive files and contributiontowards protecting our health freedom at their web site. Read their most recentsituational report and about their lawsuit at "RIPPING UP THE RAILROADTRACKS TO AUSCHWITZ". Much more here. AGoogle.com search for CodexAlimentarius. What do I think? Since the Internet is most activelysought source of on health and illness, I suspect that the supply of reallyeffective vitamins, minerals, amino acids, and herbs will move underground andbe sold via the Internet. If federal prosecutions become as serious asopponents of Codex predict, then suppliers will need to move off shore, andsmuggling of nutrients will become the business of international drugsmugglers. Heck, if that is the case, why buy ephedra when the same source willsell you cocaine? Is this the intent of Congress? To drive us into the hands ofinternational drug smugglers? Maybe we need to have U. S. regulation of dietarysupplements transferred from the Food and Drug Administration to the Departmentof Alcohol, Tobacco and Firearms. I suspect they would be better treated there,compared with commodities that are truly dangerous but allowed. The best reviewof this horrific situation that I have found is at the Australian GetALife site.You dont think that nations would do such a thing? It is a done deal in NewZealand and Australia. Whatdo I think about CODEX and the FDAs interest in pushing CODEX through theCongress as "good medicine"? I think it is a death sentence for manyAmericans, which will only benefit the pharmaceutical drug pushers, and extendthe "death-by-heart-attack century well into the 21st century, with themain benefit being pharmaceutical company health and well being, not thepublics health and well being. For that reason, I think the United States Foodand Drug Administration should immediately be split into two separate agencies,to dilute their abusive power into manageable doses. Call one of them the"Food and Beverage Administration" and the other the "Drug,Cosmetic and Medical Devices Administration". I think this would be thebest way for America to improve our national health. Why? Because if the FDAwere split up, then one agency (led by nutritionists and naturopathicphysicians) could compete with the other (led by medical doctors) to see whichagency could best improve the health of Americans. The FDA has had 70 years tofix the refined grain (depleted foods) issue, and has completely ignored it forpractical purposes, showing that there is great deference toward drugs andcontempt for superior nutrition and nutritional supplements. The currentsituation with the FDA over both aspects of our health (food and drugs) createsa lethal conflict of interest between foods and drugs, with foods easily beingdefeated by drugs simply because there is vastly more money coming at the FDA throughthe PrescriptionDrug User Fee Act of 1992 which causes the FDA to look like it is"bought and paid for" by pharmaceutical companies. Clearly, there isa major interest by the FDA, perhaps not Congressionally mandated, but realjust the same, in pleasing pharmaceutical companies with "approval"of new drugs. After all, that is the mandate of Congress, for the FDA to"approve" new drugs. Safety issues of many drugs are of great concernright now and the FDA has taken a hit over improperly approved drugs like Vioxxand Celebrexbecause they cause an increase in heart attacks. Please note that Merckwithdrew Vioxx from the market, not the FDA. In effect, the The Federalbranches of government responsible for protecting and promoting public healthare in a state of moral collapse according to BillSardi as shown on the Friendsof Freedom page. But Pfizer will not withdraw Celebrex. Does the FDAneed to act? I think so. But they wont. They dont want to go back to aspirin,which appears to work better for many anyway. Aspirin increases absorption ofmagnesium and decreases the excretion of magnesium in the urine, which raisemagnesium levels in the body which seems - in turn - to inhibit blood clottingand to lessen the blood-vessel-constricting effects of adrenaline - accordingto page 23 and 24 of "The Magnesium Factor". The public is left withonly one recourse - that being the courts. But the Bush administration istrying to terminate or greatly reduce the publics rightto sue American companies in class action lawsuits. There are manysenior-led lawsuits against pharmaceutical companies, and the Bushadministration is being pressured by the pharmaceutical companies to dosomething to relieve the pressure. Is that a good idea? I dont think so, andthe Congress should put little George in his rightful place and "Just sayno". CODEX was dealt a setback in June of 2005 by a European Union judge.Read all about it here.Tips for Diarrhea Magnesiumcan cause diarrhea atthe high dosages needed to treat depression effectively and stabilize mood. Diarrheacauses loss of magnesium and other nutrients worsening depression and creatingother serious side effects. Preventing diarrhea is absolutely mandatory. Perhaps thebest idea is to try combinations of the following natural and drug means ofcontrolling diarrhea. Too much magnesium has been found to cause diarrhea for at least 100 years. Each magnesium ion will attract about 800 molecules of water, which is usually believed to be the cause of the diarrhea. However, too much magnesium exponentially stimulates the growth of Candida yeast cells in vitro, which was preventable by added calcium. Consequently, large doses of magnesium without calcium may stimulate intestinal Candida overgrowth in the human. Consequently, magnesium should be taken using several antifungal agents, and especially garlic with coconut oil. These antifungals will also amplify the absorption of magnesium and greatly accelerate recovery but may increase toxicity of magnesium due to increased absorption. Consequently, when magnesium (without calcium) and antifungals are being used therapeutically, potential for overdose must be considered. Try wonderment of all wonderments - Kefir. Kefir, a milk product full of beneficial gut fungi and bacteria, is perfect for control and eventual elimination of overgrowths of systemic (gut) Candida Albicans, which may have been stimulated by large doses of magnesium. Kefir also contains calcium. Be careful with Kefir, because for those of us sensitive to calcium, it can bite back! Try an injection or rectal form of magnesium administration. These do not cause "diarrhea", but may cause some localized water attraction. Oral magnesium supplement are wide spectrum antibiotics. Good bacteria in the intestines are vital in natures plan to prevent diarrhea, but magnesium in the gut can kill them. Use very large amounts of probiotics such as acidophilus lactobacillus (available at pharmacies, health food and grocery stores) to maintain and replace your intestinal flora Try using the strongest fresh (refrigerated) sources you can find, and take a sufficient amount (several billion viable microorganisms) and at a frequency (3 to 5 times a day) to terminate diarrhea overnight. Take probiotics at times different from magnesium. Learn how and why treating Leaky Gut Syndrome is vital to recovery. Try Coenzyme Q-10 (100 mg am and pm), which for me along with magnesium helped my leaky gut syndrome and cardiac arrhythmias (PACs), but nothing was truly curative until I discovered the value of 2.5 grams of tauine with each meal and at bedtime. That really stopped the PACs. See this article for the science behind this amazing cardiac cure-all. Use of sacchararomyces boulardi has long been used to treat diarrhea in Europe and is becoming common in the United States. It is drawing attention in HIV/AIDS as a means to stop diarrhea. Sacchararomyces boulardii is a anti Candida Albicans fungus that will repopulate the intestines and greatly improve digestion and absorption of magnesium. It can support gut function under many adverse conditions, including food allergies, parasites, Crohns disease, Candida, Salmonella, travelers diarrhea, HIV diarrhea and Pseudomonas. Clinical studies also demonstrate the protective effect of S. boulardii in intestinal infections, including Clostridium difficile and cholera. The protective effect of S. boulardii involves several types of activity in the epithelial tissue of the digestive tract, including inactivation of bacterial toxins, stimulation of intestinal immune response, and release of polyamines. A common brand is Jarrow. Perhaps the most significant cause of irritable gut syndrome and diarrhea is consumption of refined sugars, corn syrup, dextrose and all foods with a high glycemic index. Also, see "Glycemic Index of 1200 Foods (how to live to be 100). These soluble carbohydrates should be eliminated from the diet, and consumption of other foods having a high glycemic index greatly reduced. Use magnesium taurate rather than other forms of oral magnesium. Try psyllium husk fiber or bars (other sources of soluble fiber) without sugars. Try boron supplements (3 to 12 mg/day), which help stimulate mental alertness, taken with magnesium. Try to avoid milk products, non-soluble fiber, greasy foods or foods high in sugar. They can aggravate diarrhea. Prevent dehydration by drinking sufficient fluids. The usual way to stop diarrhea using drugs is to stop the back flow of water from plasma to intestine. Opiate agonist drugs like Imodium are used to that specific purpose. (One capsule after each liquid stool.) These drugs can cause drowsiness and provoke allergies. If the above fail, terminating diarrhea with drugs such as Lomotil® will be mandatory, but do not overdose. Succeed! Depression is not a psychosis! MagnesiumTopically, by Injection or by Rectum - No Diarrhea Thelimitation of diarrhea from the oral route will force some people to usealternative routes of administering magnesium. There are four other approachesthat absolutely will not cause diarrhea. The first two require the assistanceof a physician. The first route is intramuscular, by injections. According toDr. Ruth Nyhill, M.D., the usual regime is an injection of 2 ml of 50%magnesium sulphate (1 gram magnesium sulfate, equaling 100 mg elementalmagnesium). If you want more information on this route of administration becertain to read Dr. Myhills article on treating CFS with magnesiuminjections. The second way is by an intravenous infusion (IV) ofmagnesium sulfate. IV magnesium treatment is often given in a hospitalemergency room for treatment of cardiacpain, and more recently for migraineheadaches. There is no reason that IVs of magnesium sulfate could notbe given by a physician as an outpatient treatment. The dosage is the same asintramuscular, but without the pain. Thesimplest and cheapest way of increasing blood levels of magnesium is throughtopical application of extremely strong (supersaturated) solutions of magnesiumsulfate (Epsom Salts) to the skin over large areas, such as chest, back, lowerbody and legs, or the entire body. Every pharmacy has Epsom Salts and it isextremely inexpensive. Avoid getting it in the eyes. We have used thesesaturated solutions with great effect in treating asthma in both humans anddogs (known low magnesium symptoms). Dogs lick it off where they can, butseveral applications over much of their body per day works very well. Thistechniques most likely would work in any specie needing increased blood levelsof magnesium without the intestinal side effects associated with the oralroute. This Epsom Salts treatment also makes dogs and people quite relaxed. Dr.Norman Shealy, M.D. reports great success in increasing blood levels withtopical magnesium chloride with foot soaks for 20 minutes as shownin his clinical test. Magnesiumchloride, especially as "MagicOil" by the Wolfe Clinic has a major advantage over magnesiumsulfate because it is hygroscopic and will attract water to it, thus keeping itwet on the skin and vastly more likely to be absorbed, while magnesium sulfatesimply "dries" and becomes "powdery". Magic Oil is a +25%solution of magnesium chloride, which feels "oily" on the skin. Thisshould work to cure depression after a few weeks daily application. The biggestbenefit of topical magnesium chloride administration is that the intestines arenot adversely impacted by large doses of oral magnesium. I use topicalmagnesium chloride to stop my and my dogs asthma symptoms, and topicalmagnesium chloride works faster than any prescription anti-asthma medicine.Remember that Ficks Lawsof Membrane Permeability applies here. Those laws say that the amountof any solute (magnesium) that will be absorbed is directly dependent upon thearea of contact, the concentration of the solution and the time that the soluteis in contact with the membrane. One could see that the maximum amount absorbedis obtained when all skin is treated with the strongest solution not toprecipitate out and applied 24/7. Be careful, because there is very littledocumentation (mainly Dr. Shealys)of these effects, and a foot soak may be all that is needed - as he showedmajor improvement in blood levels in just a few weeks. Me? I use it when I needto and I apply it liberally over my arms and chest. If it gets in a cut, itwill sting a bit. Note: Dr. Shealy is a world-class expert on pain managementand in 1967 he invented the TranscutaneousElectrical Nerve Stimulation (TENS Unit) for pain relief. Onthe other hand, if insects, like our dreaded Texas Fire Ants, sting on skintreated with oily magnesium chloride, there will be no immune reaction. Inother words, the sting does not hurt and the skin does not swell and becomeinflamed. Is topical magnesium chloride a cure for fire ant stings after theyoccur? I dont know yet, but I suspect so. Magnesium per rectumis another means of administering magnesium in therapeutic doses for anyillness requiring magnesium therapy. This treatment is sufficiently new thatthere is very little information on it. A google.com search shows these articles.Other similar searches showed nothing. Dr. Myhill, about treating chronicfatigue syndrome (CFS) with intra-rectal magnesium sulfate, writes: > "At a recent conference in Australia I spoke to a doctor who had been trying magnesium sulphate given PR (per rectum - i.e. up the backside! Like a suppository) with some success. If this technique works, then it would be a cheap, safe, do-it-yourself at home technique which could replace uncomfortable injections. I have now tried magnesium PR with quite a few of my patients and it has been as effective as the injections in some of them." "To try this at home, you need some Epsom salts, a 10 ml syringe (Ebys NOTE: 10 ml is less than a teaspoon in volume) and a small length of soft plastic tubing. Epsom salts are virtually pure magnesium sulphate and are available from chemists (at Boots a 500g bag costs £1.10, 3kg bags are also available). The syringe and tubing can be ordered from me (Dr. Myhill) and can be re-used so long as sensible hygienic precautions are taken between doses." "Dissolve 100g (4 oz) of Epsom salts in 200 ml (a mug) of lukewarm water. This solution can be stored in the fridge for six months, but do not forget to warm up before use." "The soft plastic tubing is meant to be cut into a short length, say 3" and pushed over the end of the syringe to allow insertion into the rectum." "To load the syringe, simply push all the air out, dip the plastic tube into the magnesium solution, and draw some magnesium sulphate back into the syringe. The exact amount is not important and I am happy for patients to experiment with smaller or larger amounts, perhaps every two to three days, according to their response. Some patients find it easier to hold the magnesium in by starting with 1 ml of the liquid and slowly increasing the dose, thus giving the back passage time to get used to the experience! If you find that you are tolerating this well, you may want to increase the concentration of Epsom salts in the water, i.e. dissolve an extra amount of the salts in the same amount of water." "If you can find somebody to insert the tube tip into your bottom, then this makes life easier! (It may need greasing with a little oil, margarine or soap). However it is perfectly possible to do it yourself. Once the tube is in position, slowly push in the plunger of the syringe and the contents will pass into the rectum. Dont then dash off to the loo or it will all be lost!" "If the magnesium is being absorbed, then I would expect patients to get the same response as from a magnesium injection, but of course without the pain. It does work for a useful proportion of CFSs so well worth trying if you get benefit from the magnesium injections." Clearly,these techniques are highly experimental. On the other hand, enemas have beenused for hundreds of years to treat constipation. Why not try one of thesemethods when oral supplements are insufficient or if they cause diarrhea? Theten milliliter syringe shown on the right would contain less than a teaspoon ofsolution, so there is little risk of leakage if left inside without furtherattention. The yellow plastic tubing was found at a hobby store, and is modelaircraft fuel line. The darkened tip has been heated with a match tocombustion, thus rounding the tip and eliminating sharp edges. Alternatively,ask your physician to prescribe 1,000 mg magnesium sulfate (100 mg elementalmagnesium) rectal suppositories. I repeat, magnesium sulfate is 10% elementalmagnesium. Then ask a local compounding pharmacist to fill your magnesium suppositoryorder. Be certain that the grade of magnesium sulfate is pharmaceutical, andthat it is amorphous or powder and not crystalline. These suppositories arestock items for compounding pharmacists and they only need to know what youwant incorporated within them. In this case we need magnesium sulfate added.These suppositories come in packages of 12 and remain in their molds until youare ready to use them. They must be kept refrigerated for them to keep theirshape. If you dont know how to use rectal suppositories visit DrugDigest.org. Inview of the fact that these rectal methods might suggest use of an enema bag,be aware that there is considerable risk of overdose which might result insignificant sedation, orworse, due to the large capacity of the bag. In fact, a recentarticle shows that a 7-year old boy died from an Epsom Salts enema. Donot do this! A reasonable enema bag preparation might be about one-half gram ofmagnesium from five grams of magnesium sulfate (1/2 level teaspoon of EpsomSalts) in 1/2 cup of warm water. Do not give more than 1/5 of the fullpreparation (100 mg of elemental magnesium). The enema bag technique is onlyfor true emergencies and is quite likely to produce overdose and can be lethal.The enema bag technique is also likely to leak unless a conscious effort ismade to hold it in. Remember that Westonin 1921 used the injection technique in these dosage sizes (about 100 to 200 mgmagnesium) as a sedative. Notice from Weston the effect of multiple treatments. Thesenon-oral dosages should be administered or prescribed only by a physician orother appropriate health-care worker, due to the risk of overdose and death. These100 mg magnesium doses appear to be the rough equivalent of 1000 mg oralmagnesium doses in terms of efficacy from what I can ascertain from the verylimited literature on the subject. People report a warming sensation(vasodilation) from the magnesium rectal treatments. The antidote is an equalamount of calcium gluconate. The calcium content of calcium gluconate is 9percent. NOTE: Sarah Mayhill, M.D., is a British doctor working both for theBritish National Health Service and with a private practice. About 10% of herNHS patients suffer from CFS and approximately 70% in her private practice haveit. Dr. Myhill is a medical advisor to Action for ME, a national supportorganization in the UK for ME/CFS sufferers. She is also the Honorary Secretaryof the British Society for Allergy Environmental and Nutritional Medicine. Sheuses a lot of magnesium in her treatment of CFS. Her homepage is http://www.drmyhill.co.uk. What About YOU? First things first. Although unfortunate, being clinically depressed ormanic-depressive is not something to be ashamed about. Seriously considertrying magnesium taurate (preferably with the other nutrients discussed in thisessay) in the doses that I used if your prescription antidepressants are notworking. Talk about your condition and get all the family and professional helpyou can. Talk it over with your physician, but be aware, he/she will likelyhave no knowledge of magnesium or its role in human health and especiallydepression. Quiz him/her and note his/her response. It is certain to be atleast entertaining! (My doctor called poison control for information!) Rememberwhat you are dealing with. In the order of illness severity, only a heartattack and death are more debilitating to a person and his/her family. Youdidnt purposefully cause it. Perhaps you could have avoided it by relievingstress before it bit you hard, but you didnt. Perhaps you didnt understandthe significance of stress, or know about the role of magnesium in managingstress, or that you may have a biochemistry that requires more magnesium thanmost people. Remember, depression is just a short little time in ones longlife where everything really seems to be going wrong. But that too will pass,if we handle ourselves correctly. For many of us, all we need to do is prevent,treat and cure benefit "structure or function" of the body and"well-being" stress and supplement our diets with magnesiumtaurate and these other nutrients. Believe me - I am not a physician, and I am not offering medical advice(either intentionally or unintentionally) in this page or in e-mail. This pageand my comments are presented only for educational purposes, which might beuseful to you and your physician in his or her treatment of your depression orbi-polar disorder. Actually, this page was written to myself as a form ofpersonal "note keeping", since I cant remember what I had forbreakfast, let alone remember complicated biochemistry and medical stuff. Iknow magnesium was useful to me and countless others who were non-responders toclassical antidepressants, but it remains to be seen what magnesium will do foryou; although from the amount of e-mail that I am receiving in response to thispage, you too can be reasonably assured that if you start magnesium taurate treatmentbenefit to the "structure or function" of the body or"well-being" and stay on it, such can be of enormous, lifesaving benefit. Concerning how much magnesium taurate is enough, I can only tell you what Itook. In a way I let my bowels tell me what was too much. At first, 1200mg a day (in split doses) for an extended period was too much for me, but nottoo much for me later or for others who have successfully, and rapidlyeliminated their depression following my lead. There are some in the FDA whobelieve the RDA of 400 mg for men and 350 for women is too low, and that manypersons need as much as 900 a day in their diet for a normal life. This may notseem too much when compared with the Canadian RDA. In Canada, the RDA is 600mg, (and us Yankees know how laid back those strange folks are - we just cantget them excited - even about terrorists trying to get us). People ask me howmuch magnesium they should take. In 2001 through half of 2003, I took 200 mgmagnesium with breakfast, 200 mg with lunch, 200 mg with supper and 400 mg atbedtime. Occasionally I took more if I felt like I needed it, sometimes anotherdosage at about 3 AM, if I woke up too early. In the later half of 2003 andearly 2004, I reduced my dosage by more than 50% due to my use of large amountsof coconut oilto eliminate yeast that impaired magnesium absorption. Each person mustdetermine the cause of low magnesium and correct that problem. Review the dosage issuesthat cause magnesium absorption and cellular retention to fail, and review the non dietary causesof hypomagnesia. Remember my comments that magnesium taurate can beused as an "aspirinfor the emotions". I cant advise anyone concerning how much isright for him or her. I dont know, and only the individual can determine howmuch is too much, and back down a bit if side-effects like diarrhea occur.Since magnesium is easily lost in the urine, doses a half hour or so beforemeals and at bedtime probably produce best results. Manic behavior in manic depression is often much more destructive, can lead toviolence, criminal behavior and financial ruin; but depression just sucks. Magnesiumdefinitely helps both extremes like lithium (actually, lithium is substitutingfor magnesium and should no longer be used in preference to magnesium). Thelist of Famous Names& Faces with Manic Depressive Disorder (bibliography) isstaggering. They dealt with it and had successful lives. Many of them did sobefore the advent of antidepressants or lithium. If they made it, so can you. Succeed! Depression is not a psychosis! Dead Doctors Dont Lie! We haveseen before at this linkthat physicians, and especially psychiatrists commit suicide more frequentlythan the rest of the population. Why? Perhaps they actually believe that theirmedicine is their "cure". Who knows. We know this is preposterous andthat proper nutrition is the only way to actual health, barring accidentalinjury or infection. I am not the first to expound upon this subject. Manyothers have spoken too. Perhaps one of the most eloquent was Dr. Joel Wallach,author of the popular audio tape "Dead Doctors Dont Lie: But Live OnesDo". In 1991, he was nominated for a Nobel Prize in Medicine (meaning aperson having already won one, nominated him). Did he get it? No. Perhaps if hehad, medicine would be vastly better today. Instead, pigs get better health carethan humans, and Dr. Wallach was vilified. Why? Veterinarians and farmers knowthat the only way to profit is from healthy pigs through nutrition, not drugs.On the other hand, it seems to me that physicians and our government [perhapsbiased by the trillion dollar health(sic) industry place economic concernsahead of people, by emphasizing drugs and demeaning nutrition. Does it makesense for the government to prohibit saying, "nutrients can cure, preventor treat disease"? I dont think so unless one is ready to call scurvy anon-disease. Do you know how much a pork chop would cost if medical doctorswere in charge of animal health? Dr. Wallach pegs it at over $325 per porkchop. Get the idea? If I get sick, sent me to a veterinarian! If you have neverheard his eloquent call for medical doctors to exercise logic concerningnutrition and long life, or if you are an old admirer who want to again hearhis world-famous lecture series, go to this pageand follow the links to his 5-part audio tape. At his peek, he made 300lectures a year. If you want to visit his site go to http://www.deaddoctors.com/ andsee a truly caring mans work. See why he says that all people and animals thatdie of "natural causes" actually die of malnutrition. Listen to histapes at learn which profession kills 300,000 people a year in the U.S. andgets paid for it! He says, "dont ever go to a physician if you want tolive a long life". Why? You need to listen to his tapes. I dont knowanything about his products, but I trust him. As you listen to him, transpose"magnesium" for his word "calcium" in each instance, andyou will see that had he made that change, he would have won the Nobel Prizefrom the very obvious benefit to human health that he would have produced. Itis little mistakes like this that have ruined lay interest in nutritionalresearch and nutrition prophets. Succeed! Depression is not a psychosis! Drug Interactions If you decide the "magnesium repletion to cure depression and otherrelated symptoms" idea sounds promising, talk it over with your ownphysician. Let him or her consider if there are any side effects or drug /magnesium interaction side effects that he or she would want to consider.However, if your physician was like mine, he wont have a clue about magnesium,and you must decide what to do yourself. If he has no clue, I would find outabout the possible interactions from him and his Physicians Desk Reference(PDR), and then seek the advise of a naturopathic physician concerningmagnesium and other nutrients as discussed here. Justbecause lithium and magnesium seemed to work together, doesnt mean that otherdrugs and magnesium will. Since lithium pulls magnesium out of cells and intothe blood stream, the combination can cause diarrhea. The Natural Pharmacisthas a very helpful drug interaction site, allowing criteria such as age andgender also to be considered. Clearly tetracycline isrendered ineffective by magnesium, and they must be taken at least two hoursapart. Othermagnesium/drug interactions are known. For example, magnesium shouldnot be taken with calcium channel blockers, because magnesium is a calciumchannel blocker. Drugs that decrease the bioavailability of magnesium include: quinidine sulphate, loop diuretics, neomycin, tetracycline, aminoglycosides, strophanthin, cisplatin, ethacrynic acid, furosemide, thiazides, disopyramide, digoxin, cyclosporin, iron, fluoride, calcium, amphotericin B, corticosteroids, cycloserine, cyclosporine, erythromycin, isoniazid, losartan, oral contraceptives, sulfamethoxazole, sulphonamides and warfarin. Drugs that are known to deplete magnesium include: Premarin (conjugated estrogens), Lasix (furosemide), Hydrochlorothiazide, Triamterene/HCTZ, Prednisone, Ortho Tri-Cyclen (norgestimate/ethinyl estradiol), Prempro (conjugated estrogens/medroxyprogesterone) and Flovent (fluticasone). Drugs that are decreased in effectiveness by magnesium include: atorvastatin, azithromycin, cimetidine, ciprofloxin (Cipro), famotidine, nitrofurantoin, nizatidine, ranitidine (by magnesium hydroxide only), tetracycline and warfarin. Drugs and nutrients that are increased in effectiveness by magnesium include: Benzodiazepines including Valium®, oral anticoagulants, calcium channel blockers, zinc, thiamine, potassium, and glipizide. Drugs that help the body retain magnesium (and are used to prevent and treat heart attacks) include aspirin, Beta-blockers, and ACE Inhibitors. Aspirin increases absorption of magnesium in the body and decreases the excretion of magnesium in the urine. Interestingly though, the reports of aspirin being helpful in preventing heart attacks used "Bufferin", which contained large amounts of magnesium. Treating patients with aspirin only did not have a similar beneficial function. Beta-blockers are used to prevent potassium and magnesium losses in people taking diuretics (water pills), undergoing cardiac surgery and in individuals who have had a heart attack. They are also used as anti-anxiety drugs. Beta-blockers inhibit the effects of one of the catcholomines, the stress hormone adrenaline. ACE (angiotensin-concerting enzyme) inhibitors that also have antioxidant activity help retain magnesium. Your doctor using the Physicians Desk Reference and the drug insert arethe gold standards for checking drug interaction. Be very careful usingmagnesium if you have kidney disease, because the main occurrence of sideeffect will be in kidney patients that retain too much magnesium (rarelyapplies to us). Succeed! Depression is not a psychosis! Magnesium Compounds That Work,That Are Ineffective, or That Injure ON A PRECAUTIONARY NOTE, two amino acid chelates of magnesium(magnesium aspartate, magnesium glutamate) MUST be avoided in treatingdepression. Each of these amino acid complexes of magnesium has been reportedto worsen depression. Aspartate and glutamateact as neurotransmitters in the brain and retina by facilitatingthe transmission of from neuron to neuron. Too much aspartate or glutamate inthe brain kills certain neurons by allowing the influx of too much calcium intothe cells. This influx triggers excessive amounts of free radicals, which killthe cells. The neural cell damage that can be caused by excessive aspartate andglutamate is why they are referred to as "excitotoxins." They"excite" or stimulate the neural cells to death. Aspartate is a principalingredient in the highly maligned Aspartame sweetener. To avoid aggravatingdepression with super-sweeteners, instead use Stevia. Succeed! Depression is not a psychosis! Toxicology The Dictionary of Minerals reports toxicity of magnesium is rare whentaken as dietary supplements. Even so, there are some important toxicologyconcerns: Too much magnesium has been associated with diarrhea for at least 100 years. Each magnesium ion will attract about 800 molecules of water, which is usually believed to be the cause of the diarrhea. However, too much magnesium exponentially stimulates the growth of Candida yeast cells in vitro, which was preventable by added calcium. Consequently, large doses of magnesium without calcium may stimulate intestinal Candida overgrowth. Consequently, magnesium should be taken using antifungal agents, and especially garlic and coconut oil, or prescription antifungal drugs. Antifungals will amplify the absorption of magnesium, greatly accelerate recovery and may increase toxicity of magnesium due to increased absorption. Consequently, when magnesium (without calcium) is being used therapeutically, consideration of overdose must be given consideration. Magnesium hydroxide (such as Milk of Magnesia) is ABSOLUTELY CONTRAINDICATED in the treatment of depression because of poor bioavailability, because it has no known use other than as a laxative and de-acidifier, which will impair mineral absorption. Magnesium toxicity is common in those with kidney failure. High dosage magnesium is contraindicated with kidney or adrenal failure, or in severe hypothyroidism (but only in cases where the thyroid disease has caused hypermagnesia). Magnesium aspartate and magnesium glutamate worsen depression. If you are taking a magnesium product identified as "Magnesium Amino Acid Chelate" and your depression worsens greatly, you probably are taking one of these amino acid chelates of magnesium. Be VERY careful. Magnesium sulfate, a purgative, must not be taken by those with kidney problems, and probably should not be taken internally by anyone in large doses, unless they want diarrhea. Magnesium sulfate, commonly called Epsom Salts, is readily available at nearly every pharmacy with directions for preparing a relaxing bath. These baths are capable of causing people to relax to the point that they fall asleep - thus the potential for drowning (and diarrhea if the bath are VERY strong and lasts more than an hour). People having hypermagnesia from any disorder must not supplement magnesium (no need). Magnesium supplements usually worsen myasthenia gravis because it appears to be a symptom of manganese deficiency. Large amounts of magnesium, of course, can lower manganese in the body. Known symptoms of magnesium toxicity include flushing of the skin, thirst, low blood pressure, loss of reflexes and respiratory depression and coma. Excessively high blood levels lead to anesthesia and eventually heart failure. Treatment of severe magnesium intoxication is a purely medical matter involving circulatory and respiratory support combined with intravenous administration of calcium gluconate. Regardless of any claimed toxicity for magnesium by prescription drug enthusiasts (physicians), all of us need to remember that our livers see all drugs (prescription, OTC and illegal) as foreign and tries to detoxify them. Consequently, about 50 times the amount needed in vitro is often prescribed to defeat this liver function, sometimes resulting in serious liver damage and death. This does not happen with magnesium and other nutrients. Review this case of a fatality induced by using an entire box of Epsom Salts over a 2-day period as a gargle for halitosis. Am I afraid that in the long run we (meaning those of us that have magnesiumresponsive mood disorders) will overdose on magnesium? No. Not at the dosagesconsidered on this page, unless absorption is so greatly increased byantifungals that toxicity occurs. Generally, we leak magnesium throughour sweat, urine and feces (particularly when we have diarrhea) more than otherpeople. Think of us as being water (magnesium) tanks, and that we have allowedthe tank to become nearly empty. We have the dual problem of filling the tankback up to normal levels as well as getting our daily usage (leakage) met atthe same time. Our health was not built in a day, but over a lifetime; and itmay take years to refill our tanks. We leak. However, chromium, taurine,vanadium, boron, Omega-3 EFA and lecithin are important plug-like nutrients,capable of stopping that leakage (if sugars and calcium are kept low) andallowing our magnesium reserves to be restored to normal. If, after takingmagnesium for a year or two at high dosages, daytime sleepiness becomes aproblem, one can be assured that magnesium reserves have been restored andintake of supplemental magnesium can be reduced or replaced totally with highmagnesium content foods. However, some people will require supplementalmagnesium for the rest of their lives to maintain a good mood. Succeed! Depression is not a psychosis! Economic Sources of Magnesium Magnesium chloride has been used for about 85 years to treat and cure a widevariety of "diseases" including depression. SeeWalter Lasts site for the remarkable history and uses of use ofmagnesium chloride in medicine and health. It is an inexpensive form ofmagnesium often used as an industrial chemical, fertilizer, human and animalnutrient. Walter Last reports that hydrated magnesium chloride (the kind youcan buy over the counter) contains about 120 mg of magnesium per gram (12%magnesium) or 600 mg elemental magnesium per rounded teaspoon. It is also apowerful and natural antibacterial agent. This form of magnesium can often bepurchased in parts of the world where more expensive organic compounds ofmagnesium (such as magnesium taurate) are unavailable and emergency servicesfrom me are unavailable or much too expensive due to distance. NOTE: Ihave shipped long distances, for example to a prince in Africa, but it was veryexpensive and not advised unless absolutely necessary. Magnesium chloride issufficiently inexpensive that it is used by the hundreds of truckloads toprevent icing and to de-ice airport runways, public roads and highways. Follow thislink for "magnesium chloride" "dietarysupplements". Magnesium chloride is the most absorbable form of magnesiumfor human use, because stomach acid (hydrochloric acid) converts all otherbiologically available compounds of magnesium to magnesium chloride before theyare absorbed. Magnesium chloride breaks down into magnesium ions and chlorideupon absorption, and tastes terrible - requiring dilution in water. Iftaurine can be obtained, addition of taurine (10 grams a day) should equal theeffect of 1000 mg of magnesium from magnesium taurate. Thislink will take you to sources of "glycine dietarysupplements". Succeed! Depression is not a psychosis! After the question of dosage, the most frequent question that people ask me is,"Why dont physicians know about this?" Well, the answer to thatquestion could easily cause me to write another web page at least as long andtedious as this one. Some of them know and are very sympathetic and/orknowledgeable about nutritional healing. A wonderful example is Dr. Joseph Mercola, MD. Whatever hesays, you can bet your life and your familys lives that he is correct. I knowof no other medical doctor that I would trust more. Others have a laymansunderstanding of nutrition and generally are supportive, while most seem tosubscribe to the American Medical Associations position that, "You getall the nutrition you need from your food". Are medical doctors [mainlygeneral practitioners (GPs)] correct on this matter? No. Particularly as thequestion relates to magnesium and its depletion from grains during the last 100years of grain refining, with massive injury to both mental and physicalhealth. In fact, the entire field of medicine in the United States and the Westin general is built upon the incorrect ratio ofdietary calcium to magnesium. This single error accounts for about 60%of our medical expenses, morbidity and mortality. Will this change? I wonder.From the large number of inquiries that I receive from chiropractors,pharmacists, nutritionists, psychologists, psychiatrists and faculty, I thinkthere is a some hope for change, but perhaps as a trickle-down effect fromthese leaders. However, in the defense of modern medical doctors and medicalscience, no profession in history has done a better job of rescuing us inemergencies and saving our lives from acute illnesses. PERIOD! I gladly andgratefully tip my hat to those brave hospital cardiologists that are rescuingpeople with IV magnesium sulfate. The vast majority of chronic diseases,particularly mental, cardiac and circulatory disorders, and deaths by"natural causes" remain nutritional deficiencies in disguise, forwhich most general practice physicians (MDs) have either no training or verylittle training, and apparently no or little interest, thus making manycardiologists feed magnesium to people by IV drip! How unfortunate! Death by Modern Medicine Medical doctors (MDs) are reported in medical journals reviewed by JosephMercola MD to be the number 3 cause ofdeath in the United States (about 250,000 cases per year, equal tokilling all people in a town the size of Galveston, Texas). Another much higherestimate by Gary Null PhD, Carolyn Dean MD ND, Martin Feldman MD, Debora RasioMD, and Dorothy Smith PhD in 2003 shows the total number of iatrogenic deathsin an article titled Deathby Medicine to be about 780,000 (equivalent to killing all the peoplein a city slightly larger than Austin, Texas). From their data, it is evidentthat the American medical system is the leading cause of death and injury inthe United States, considerably ahead of the 2001 heart disease annual deathrate of 700,000 and the annual cancer death rate of 550,000. Heart attack is anew disease that has come about in this century. Prior to 1925, there wasalmost no knowledge of this disease. We have seen from international data thatninety-percent of these heart attacks deaths in the United States are caused byour lethal high-calciumlow-magnesium diets. Ifwe wanted to blame medical doctors (people with enormous financial interests intreating - but not necessarily in preventing heart attacks), then we can addsome of these numbers and come up with nearly 1,500,000 deaths per year causedby physicians in the United States, which clearly puts physicians as theleading cause of death in the United States. This is the same as killing all ofthe people in a city the size of Philadelphia, PA, each and every year. Andthey complain about their insurance rates being too high? Duh!!! If the radicalIslamics killed 1,500,000 Americans a year, there would be thermonuclear war! Isuspect insurance companies would be better off insuring radical, suicidalbomber Islamics! An article showing the grave extent of the magnesiumdeficiency problem was written by Jane E. Brody, the well known New York Timeshealth writer, and was published recently in the Times and reprinted in manyother major newspapers. The Brody article cited Seelig and the Alturas andcovered all topics in a most concise manner. I think it is mandatory reading.This single article, if given the consideration it truly deserves, places thegeneral reading public far ahead of physicians in their understanding andknowledge of this epidemic catastrophe. The Brody article is located here. Ifyou are not aware of the severity of this national and Western culturalcatastrophe, then you must educate yourself. A really good place to start ishere at the article by Gary Null PhD, Carolyn Dean MD ND, Martin Feldman MDDebora Rasio MD, and Dorothy Smith PhD titled "Deathby Medicine". Next, buy Dr. Deans 2005 book "Death by Modern Medicine",but first, read thereviews of this book. "Death by Modern Medicine" by CarolynDean is a blockbuster book that will bust the blockbuster drugs that havebecome the hallmark of modern medicine. It contains an unprecedented threeforewords by Dr. Abram Hoffer, the father of orthomolecular medicine, Dr.Joseph Mercola, well known for his top-rated web site mercola.com, and Dr. Julian Whitakerauthor of the famous health newsletter Healthand Healing. This book identifies the tragic aspects of a medicalsystem that in its short history of about eighty years, has managed to killtens of millions of victims. Dr. Deans widely circulated paper, "Death byMedicine", written for Dr. Gary Null in November 2003, was the first toidentify the extent of these casualties. Dr. Dean verified that from 1990-2000about 7.8 million victims suffered Death by Medicine. Many people were shockedat this figure, but since then peoples eyes have been opened to the fullhorror of modern medicine. Her book is a tale of propaganda, health carebureaucracy, the business of cancer, our own personal addictions to sugar anddrugs, and the denial we all harbor to help us cope with the overwhelmingburden, are woven into this 360-page volume. if you have any interest insurviving "modern medicine", you must read this book. Here is awonderful Opus cartoonthat makes fun of this horrific problem. IfGPs knew better, I feel certain that their attitudes would be different, butthey are the willing victims of multi-billion dollar physician educational(propaganda) programs by pharmaceutical drug pushers, and trillion dollarhospital investments. Physicians and hospitals have enormous financialincentives that steer them away from no-cost prevention-of-disease and towardsexpensive-treatment-of-diseases at our expense. They have no financialincentive under our economic system to keep you well, or to get you totallywell. Their role seems to be to keep you sufficiently well so that you can getto their office or the hospital, perhaps because they no longer make housecalls. They are unlikely to make nutritional recommendations that aresufficiently specific that would benefit the patients particular illness. Inother words, they are not likely to recommend nutrients to do the work ofpharmaceutical drugs. Some day, if we are lucky, the playing field willreverse, and it will be illegal to prescribe a prescription drug to treat anillness caused by a nutritional deficit - as many of todays chronic diseasesare. The international pharmaceutical drug pushers are very much aware of thismajor health-care issue, and they desperately want control of all nutrients (herbs,vitamins, minerals, and amino acids), thus their behind the scenes push to haveCODEXimplemented. At that time, these agents will miraculously be discovered byphysicians to "cure everything!" However, you will be paying your 15%annual tithe to Big Pharma from then on. I now think that CODEX will be a deathsentence to millions of people, and it will perpetuate and increase theiatrogenic deaths illuminated here. Ina concession to international pharmaceutical drug companies when passing the Dietary Supplement andHealth Education Act of 1984 (DSHEA), which took herbs, vitamins,minerals and amino acids out of effective control of the U.S. FDA, an outrightlie was written into law by the Congress. What lie? The lie that you see onnearly every package of vitamins, minerals, herbs, and amino acids that"support" a bodily structure or function. Those infamous words, "Thisproduct is not intended to diagnose, treat, cure or prevent any disease".In fact, these words are directly from the DSHEA: "The DSHEA providesfor the use of various types of statements on the label of dietary supplements,although claims may not be made about the use of a dietary supplement todiagnose, prevent, mitigate, treat, or cure a specific disease (unless approvedunder the new drug provisions of the FD&C Act). For example, a product maynot carry the claim "cures cancer" or "treats arthritis."Appropriate health claims authorized by FDA--such as the claim linking folicacid and reduce risk of neural tube birth defects and the claim that calciummay reduce the risk of osteoporosis--may be made in supplement labeling if theproduct qualifies to bear the claim. Under DSHEA, firms can make statementsabout classical nutrient deficiency diseases--as long as these statementsdisclose the prevalence of the disease in the United States. In addition,manufacturers may describe the supplements effects on "structure orfunction" of the body or the "well-being" achieved by consumingthe dietary ingredient. To use these claims, manufacturers must havesubstantiation that the statements are truthful and not misleading and theproduct label must bear the statement, "This statement has not beenevaluated by the Food and Drug Administration. This product is not intended todiagnose, treat, cure, or prevent any disease." Unlike health claims,nutritional support statements need not be approved by FDA before manufacturersmarket products bearing the statements, however, the agency must be notified nolater than 30 days after a product that bears the claim is first marketed.Consequently, the Congress, even though it unknowingly lied, wisely made theseelements-of-life the property of the public and not the property of thepharmaceutical drug pushers. I note here the comment in DSHEA, "calciummay reduce the risk of osteoporosis, is another inaccuracy, which probablyhas set the nations nutritional supplement companies, nutritionists, MDs, NDs,and nearly all of American health care system off onto the wrong path. As wenow know, the real cure for osteoporosis is magnesium andother minerals such as zinc, copper and so forth, as well as the obviousmineral, calcium. Thereis much more wrong with modern American medicine. Modern medicine is doing afar, far worse job of treating disease today and saving lives from seriousinjuries than doctors were doing over 200 years ago. So what has gone wrong?Lets look way back in history. Medical results from the British battle ofWaterloo against Napoleons huge French army in the early 19th century tellsthe story. This was the huge defeat for Napoleon and a great win for theBritish. Consequently, the records from the battle are part of the Britishnational history. The medical records have kept to this day and are very clear.Vastly more people are dying in todays modern hospitals from serious injurythan died from the medical treatments given to the injured soldiers in theBattle of Waterloo. Of the 50 privates in the 13th Light Dragoons wounded bysabres, gunfire and cannon injuries at Waterloo, only two subsequently died.This was despite that fact that all had serious infections and nearly completeshut down of all internal organs, only two of 50, or 4% died as a result. Just60 years later, during the American Civil War, new surgical techniques usedunclean scalpels and butcher knives to remove injured arms and legs. The resultwas nearly 1/5 or 20% of the injured soldiers were dying days later of severeinfections and septicemia caused by their medical treatments. A greaterpercentage of Civil War soldiers were dying from the medical care they received,than were dying from enemy gunfire on the battlefield. This problem was solvedwhen doctors actually started washing their hands before surgery and evencleaning their surgical tools. But... Comparethese statistics to what is happening in todays modern hospitals wheresurgical patients are dying at even far greater rates, about 30%, fromsepticemia and major organ shutdown. Something is going wrong in modernhospitals. Our record is worse than the record of the Civil War surgeons whodid not wash their hands or pay much attention to hygiene. So what can be goingso terribly wrong? And why is nobody shouting about this? Why is the medicalprofession going backwards? Survivalstatistics from the battle of Waterloo throw up a radical theory - thatmultiple organ failure, triggered by severe trauma and subsequent infection,may represent the bodys last-ditch attempt to survive a critical illness. Byswitching itself off to become dormant, like hibernating animals during extremecold, the body may thus be able to better care for itself through the criticalperiod. Support for this theory comes from the fact that the organs invariablyrecovered, to the point of appearing remarkably normal, within days to weekswhen the patient survives. Despitethe lack of antibiotics, blood transfusions, life-support machines and otherparaphernalia of modern American medical care, most of the British Waterloosoldiers recovered from life-threatening injuries. Even lowering thetemperature of feverish patients is counter-productive. Lowering thetemperature of a feverish patient shuts down critical parts of the patientsimmune system opening the body to increased bacterial and viral infections, orsepticemia, which days later results in complete organ shutdown and death. Whatseems to be a successful treatment, lowering the fever, actually results dayslater in death. This is now very common and lowering fever is a standard of"care". Thisis why so many people are dying in todays hospitals. The doctors are killingtheir own patients by mistakenly treating the fever as if it were a disease,and not by treating the fever as the human body successfully mounting an attackagainst infection. The fever should be raised and not lowered. Why arentAmerican doctors aware of such simple facts? Quite simply because for over 100years, American medicine headed by the Rockefeller University andRockefeller-owned pharmaceutical drug pushers have taught doctors that alldiseases (any variation from "normal) should be treated with profit-makingmedicines and procedures. Anything that looks like inexpensive home remedies oreven letting the patients body treat the disease for free, is pooh-poohed inthe prestigious medical journals, and outlawed by the governments FDA. CODEXwill make this problem worse. Toprotect their practice from lawsuits, American doctors must go along with themedical professions standards of care. For most doctors those standards aretypified by what is found in the latest edition of the Merck Manual. Of course,the Merck Manual is published by Merck & Co., Inc. -- a pharmaceuticalcompany. This is why todays hospitals have a death rate of about 30% fromsepticemia following heroic life-saving attempts with modern American medicaltechniques and medications, while the severely injured British soldiers of the13th Light Dragoons following the battle of Waterloo, only had a death rate of4%. That is a 750 percent increase in Death by Medicine in the last 200 years.Is there something wrong with modern American medicine? You betcha. Naturopathic Medicine Onthe other hand, lets look at another type of physician, the naturopathicphysician, naturopath or ND. They are interested in nutritional and naturaltherapies and specifically non-pharmaceutical approaches to taking care ofpeoples health care needs, whether they be acute or chronic illnesses,conditions or injuries. However, as a concession to "medical doctors"and the extremely powerful American Medical Association, they are not allowedto prescribe drugs, and are not called "medical doctors", nor arethey listed in the yellow pages of telephone books along with "medicaldoctors". They are listed separately as "naturopathicphysicians" or "naturopaths" in most yellow pages, a practicewhich I think is highly prejudicial. They probably do not make as much money asdo medical doctors, and as a rule dont advertise. Of course, medical doctorsbelittle them, even though some NDs have more training and education than MDs inthe areas of biomedicine that we need the most. Theoriginal intention of medicine as advocated by Hippocrates is no longerreflected in the way many medical doctors practice medicine (due to their useof drugs and not nutrition). The word "physician" is from the Greekroot meaning "nature". Hippocrates, a Greek physician who lived 2400years ago, should be considered the earliest predecessor of"naturopathic" physicians, not of "medical" physicians.Hippocrates taught that nature is healer of all diseases, thus his formulationof the concept "vis medicatrix naturae" -- meaning the healing powerof nature. This concept has long been at the core of indigenous medicine inmany cultures around the world and remains one of the central themes of naturopathicphilosophy even in the United States to this day. The word"naturopathy" was first used in the US over 100 years ago. But thenatural therapies and the philosophy on which naturopathy are based have beeneffectively used to treat diseases since ancient times. American naturopathicphysicians (NDs) receive extensive training in and use therapies that areprimarily natural (hence the name naturopathic) and nontoxic, includingclinical nutrition, homeopathy, botanical medicine, hydrotherapy, physical medicine,and counseling. Many NDs have additional training and certification inacupuncture and home birthing. These NDs, who have attended naturopathicmedical colleges recognized by the US Department of Education, practicemedicine as primary health care providers and are increasingly acknowledged asleaders in bringing about progressive changes in the nations medical system. Youcan find a naturopathic physician in your area by accessing the American Association of NaturopathicPhysicians web site and searching their directory. I personallyencourage anyone with a chronic illness or chronic health condition, evencancer, to seek the advise and knowledge of these fine, caring people. Yes,even cancer. Naturopathic medicine is also at the foreground of cancerprevention and treatment, and when used with cancer chemotherapy, it is veryeffective. This is what the "CancerTreatment Centers of America" program is all about. Yes, the sameoutfit that you see on cable TV advertising that they "have treatmentoptions that you dont know about". Clearly, if our immune systemfunctions are restored with nutrients (many chemotherapy agents deplete one ormore nutrients or harm our ability to absorb nutrients), we have a much betterchance of surviving cancer. In fact, my career in medical and biomedicalresearch started with my observation that supplemental zinc with appropriatechemotherapy cured my 3-year old daughters acute lymphocytic leukemia in 2weeks. See my original cure for leukemia with zinc research report here, which led tomy cure for common colds, which ledto my cure for herpes,and my cure for mononucleosisand so forth... Succeed! Depression is not a psychosis! What Does Dr. Atkins Say AboutMagnesium? Perhapsthe most influential "weight loss" or "diet" phenomenon ofrecent history is the "Atkins Diet". Dr. Robert C. Atkins books ondiet have caused a health care revolution that is still unfolding. His basicpoint is to avoid carbohydrates, specifically refined wheat products. Why?Simply this, to avoid eating foods that are depleted of magnesium. Perhaps byavoiding them, people will find other foods like nuts, green leafy vegetablesand magnesium supplements that will improve their health and lives. On pages119 through 123 of his 1999 book "Dr.Atkins Vita-Nutrient Solution - Natures Answer to Drugs" arethese important words: > MAGNESIUM: The hearts most important mineral Magnesium is scientifically established as the hearts most important mineral. More than three hundred different enzymes in the body depend on the mineral, yet some 80 percent of all Americans fail to consume as much as they need. Even worse, few cardiologists bother to prescribe it routinely. No wonder heart disease is so rampant. Elemental medicine We face threats to rob us of magnesium no matter where we turn. The mineral is all but absent from the sugary junk foods that now constitute . More than 35 percent of the average persons diet. Crops are grown in soil that steadily becomes more deficient in the mineral. The body expends much of its meager supply to cleanse itself of smog, pesticides, and so many other toxins. Perspiration and stress drain off whats left, as do diuretics and other drugs. For most of us, a deficiency seems unavoidable. Age brings it even closer to reality. As we get older, we absorb less of many nutrients, including magnesium, from food. Because of dental problems, we may avoid nuts, seeds, and other good dietary-sources, and we will probably be taking more nutrient-depleting medications. Magnesium touches almost every aspect of our health, but because its one of the strongest explanations for the presence or absence of cardiac problems, the heart is a good place to start. Cardiovascular Disease. As a cardiologist, I see more people for heart-related ailments than for any other problem. About 98 percent, Id guess, need magnesium, and all of them benefit from it. Yet only a handful of them were-ever instructed by their previous doctors to take it. The following summary of whats possible with regular supplement use reads more like a wish list for any person with heart disorders. Irregular heart rhythms become more stable. High blood pressure improves. The body keeps a better balance of potassium, another important cardiovascular mineral. The heart pumps a larger volume of blood with no extra demand for oxygen. Constricted blood vessels relax, allowing blood to flow more freely. The chest pains of angina pectoris strike less frequently. By not allowing platelets to clump together, the blood becomes less likely to form artery-blocking clots. HDL cholesterol rises and LDL cholesterol falls. Acute Heart Attacks. Hospital cardiologists are quite interested in what magnesium can do when a patient is first admitted to a coronary care unit, because half a dozen studies showed it to be effective in preventing complications. This led to a larger study, which failed to demonstrate benefit. Dr. Mildred Seelig, the magnesium guru, feels that the minerals benefits could be maintained with the individualization of treatment and a flexible dosage system. Magnesium, when given by the vein, as in these studies, can stabilize or destabilize the heart. Blood Sugar Disorders. How well the body metabolizes sugar is tightly linked to magnesium, making the mineral essential to anyone with diabetes or insulin resistance. In and of itself, poor sugar control raises the risk of a magnesium deficiency, which in turn further impairs sugar metabolism. Supplements allow people with Type II diabetes to regulate blood sugar more easily. As a result, their need for oral diabetes drugs usually diminishes and could disappear altogether. People susceptible to bouts of hypoglycemia, too, can stabilize the roller-coaster rise and fall of their blood sugar. Although the mineral doesnt affect Type I diabetes as dramatically, it is nevertheless a benefactor that shouldnt be neglected. High Blood Pressure. Following our nutritional approach, about 80 percent of the Atkins Centers hypertension patients reduce or eliminate their need for diuretics and other blood pressure medications. All of the ingredients we use contribute to that success, but magnesium is largely responsible. A person with high blood pressure typically will have a lower level of the mineral compared with somebody who has a healthier blood pressure reading. Supplements work like a natural calcium channel blocker, another standard anti-hypertension drug, but without ill effects. Excess insulin in the blood, low potassium levels, constricted blood vessels-the nutrient addresses all of the conditions primary causes simultaneously. Pregnancy Complications. For expectant mothers and their babies, magnesium supplements can frequently overcome several serious blood pressure disorders that may arise. As medicine has known for more than fifty years, the mineral is a choice treatment for preeclampsia, a relatively common complication seen in the latter part of pregnancy that raises blood pressure and causes water retention, among other problems. In extreme cases of preeclampsia, a woman may suffer convulsions or lapse into a coma. Again, magnesium is a very effective treatment. Some 60 percent of all such hypertension-related complications could be avoided, researchers estimate, if pregnant women were to take supplements. By administering magnesium instead of drugs, doctors also might be able to rescue certain babies whose lives are endangered by high blood pressure. As described in a medical journal article, physicians gave the nutrient to seven infants after all other medications failed to help them. The babies were expected to die, but injections of magnesium sulfate brought down their blood pressure and saved their lives. Mitral Valve Prolapse. This condition, which involves a weakness of a valve in the heart, increases magnesium excretion. Resupplying the mineral helps to correct low blood sugar, one of the main problems linked to mitral valve prolapse, and counteracts fatigue, which probably is the most frequently encountered symptom. Asthma. By diminishing wheezing and encouraging bronchial muscles to relax, magnesium reinforces my better-breathing programs for bronchitis, emphysema, and other chronic lung disorders. When given intravenously, it stops an asthma attack cold. Safe and consistently effective, this "IV push," as we call it, is also a great on-the-spot treatment for allergic flare-ups. Migraines. The IV push significantly relieves migraine headaches, too. In most cases itll stave off a recurrence for more than twenty-four hours. Not surprisingly, people who enjoy the most prolonged relief usually have the lowest blood levels of the mineral. Regular migraine sufferers need not anticipate a future of daily visits to the doctors office if they want sustained relief; taking magnesium orally is a good preventive. Fibromyalgia. For anyone who copes with the muscle and joint pains of this rheumatic ailment, magnesium is a valuable part of an effective treatment. I also use it, in a dosage of 300-600 mg, for a related condition, chronic fatigue syndrome. Its especially powerful when combined with 1-2 grams of malic acid. Brain Function. Magnesium readings are markedly lower than average in people who have multiple sclerosis, Parkinsons, and Alzheimers or other types of dementia. Many of them have an unusually high amount of aluminum in their brains, and the metal is known to interfere with magnesium. Institutionalized psychiatric patients also have reduced blood levels of the mineral. An outright deficiency can aggravate psychiatric symptoms, some research suggests, and cause the brain to age prematurely. Osteoporosis. For preventing and perhaps reversing osteoporosis, magnesium might be more important than calcium. Although constituting only a fraction of bone matter, the mineral plays a disproportionately important role, balancing the bodys calcium supply and keeping it from being excreted. Some scientists go so far as to say that how much magnesium we eat is a stronger predictor of bone density than calcium consumption. Without enough magnesium and the other trace minerals, any additional calcium we ingest will be deposited not around our bones, but elsewhere, perhaps in the walls of our arteries. Strength Training. Muscle growth and strength, especially from a weight-training program, depends on magnesium. Supplements attracted a good deal of interest from competitors in the 1988 Olympics, especially athletes involved in rowing, weight lifting, and other power sports. Premenstrual Tension. Supplements have decreased the number of mood swings that may occur as menstruation nears. They also help tame premenstrual migraines and yeast infections. Cancer. Scientists havent studied humans directly for a link between magnesium and cancer, but other evidence suggests a strong relationship. For instance, tumors can develop in animals that eat a low-magnesium diet, and higher rates of the disease seem to exist where the local water and soil contain low concentrations. Cancer drugs and radiation therapy, in addition, deplete the body of magnesium. Other Conditions. Magnesium should be a part of any nutrient program for better sleep. Besides encouraging a more restful slumber, it works against bruxism, an involuntary grinding of the teeth while asleep. Its wide range of actions helps against chemical sensitivities, bacterial and viral, infections, leg cramps, kidney stones, and intermittent claudication, an impairment in blood flow to the legs that causes pain upon exertion. Supplement Suggestions. Giving the cells in your body the optimal amount of magnesium isnt as easy as swallowing a supplement or two every day. Quantity alone is no guarantee, and an overload could be harmful. For a nutrient like vitamin C, to give an example, you can dose yourself into a case of diarrhea, but thats about the only side effect youll suffer. Big doses of magnesium, particularly magnesium oxide (not absorbed into blood by more than 4 percent), also cause diarrhea, which makes it a good short-term, treatment for chronic constipation, but diarrhea is not a benign consequence. Taking too much could be dangerous, especially if your bloods concentration already is high, as can happen when certain kidney problems prevent the mineral from being excreted. No one with seriously diminished kidney function should take magnesium supplements (or any other mineral supplement) without careful medical supervision. Blood tests are the best way to determine your true need and track the effectiveness of supplements. Dont rely on standard blood serum measurements. They can be misleading and will often fail to detect a deficiency. A much better gauge is the minerals concentration within red blood cells. Ive found that the optimum dosage for magnesium-related health problems typically brings the red blood cell reading to a point slightly above the middle of the "normal" range. For most people this usually translates into a daily dosage of 400-1,000 mg. To reach the ideal point, some formulations work better than others. Magnesium oxide, the type most frequently found in mineral supplements, does not raise the standard blood serum level (because it is not absorbed), while other forms deliver the nutrient to tissue cells. My favorite is magnesium orotate, which, although once difficult to find, is now beginning to be found in health food stores. Other good forms are magnesium taurate, magnesium chloride, magnesium glycinate, and magnesium aspartate. As an alternative, go soak your feet-and the rest of your body. Epsom salts are known chemically as magnesium sulfate, and your skin will absorb as much of the mineral as you need. Drawing a bath and pouring in some Epsom salts can be as nourishing as it is relaxing. DoesntDr. Atkins sound more like a "naturopath" than a "medicaldoctor"? Yes, he does, and he is one of the main movers and shakers of ourtime, yet Dr. Atkins was a medical doctor and a board certified cardiologist.Very few people have had such a beneficial effect on other peoples lives asDr. Atkins. I strongly encourage you to read his books and follow his diets,without the improperly interpreted emphasis on eating large amounts of meat. Henever said to do that, but his work has been perverted to suggest that gluttonyfor meat is "good". Read what he said, not what the critics say hesaid. Doyou think Dr. Atkins was right? General Mills, the nations No. 2 cereal maker,seems to think so. They announcedplans to convert all their cereals - including Trix, Cocoa Puffs andLucky Charms - into whole grain products, complete with magnesium, manganeseand folic acid. Already Cheerios, Wheaties and Total are whole grain. Onenutrition expert ranks the change as one of the most significant food industryactions in decades. "(It) could signal the most comprehensive improvementin the nations food supply since the government began mandatory fortificationof grains in the 1940s," says David Kessler, former commissioner of theFood and Drug Administration. Those rules helped eradicate many dietarydiseases. Nutritionists say whole grain flours are far healthier than refinedcorn meal or wheat flour. "If whole grain becomes a marketing magnet, itcould lead the way to a healthier nation," says Dr. Neal Barnard, authorof Breaking the Food Seduction. "The laxative industry could go intoliquidation." Guess what guys! The cardiac care units at hospitals mightvery well go bankrupt too! This looks like a major health care revolution inthe making! Now, if Kellogg and the white flower industry will follow GeneralMills lead... Hummm... But! George remains a skeptic. It is entirely possibleto engineer foods in a way that the magnesium remains in the food, but is sotightly bound that it will not support life, either bacterial life or humanlife. It all depends on what they do to magnesium. If they chelate it withbinders to the point that the food will not go bad over time to preserve shelflife, will it still remain biologically available to people? If you ever findthe term "EDTA" on the list of ingredients of any processed food,rest assured that any minerals in that package will be chelated to a point thatthey will not be biologically available. This is an academic subject of "solutionchemistry". Knowing how "chelators" and "metalbinders" work, I remain skeptical of all processed foods. Concluding Remarks - DrugsSubstituting for Magnesium In conclusion, I believe magnesium should be an essential component oftreatment for depression, bi-polar disorder, attention deficit disorder andmany other related hyperemotional mental conditions. It may be the onlytreatment needed, or taurine, boron, Omega-3 EFAs, CoQ10 and lecithin may alsobe required. A sound nutrition program limited in calcium intake appearsessential for our mental health. Psychiatric drugs may also be needed,particularly at the beginning, but some effective drug treatments act simply bymoving magnesium from storage depots (usually bone) into the blood where it canbe utilized by the brain, and other drugs simply work due to their placeboeffect. Perhaps the drug-related points that I would like the reader toremember from this essay are as follows: Magnesium is not a drug, but a nutrient critical to cellular and neurocellular health. It works inside the cells and tests for it using serum (obviously outside of cells) are totally misleading. Intracellular spectroscopy testing is the only truly reliable way to determine intracellular magnesium concentrations. Magnesium has been known to relax nearly all "hyperexcitability" neurological conditions including depression since Westons article written in 1921. Magnesium ion is natures natural calcium channel blocker, and prevents neurotoxicity from excess dietary calcium. Aspirin, Beta-blockers and ACE inhibitors each raise magnesium in the body as part of their drug effect. Magnesium is released into the blood from body stores by several anti-depressive psychiatric drugs, including lithium for bi-polar and other disorders, and the amphetamine dextroamphetamine for treatment of Attention Deficit Hyperactivity disorder (ADHD). Electroconvulsive shock treatment (ECT) lowers calcium concentrations thus promoting a more healthful calcium/magnesium ratio. Magnesium helps people fall asleep, a critical component in treating depression, anxiety and insomnia. Magnesium deficiency, whether induced by stress or poor diet is known to the NIH and many researchers to cause depression and other severe mental health conditions. Omega-3 EFAs, taurine and boron are helpful in increasing the effectiveness of magnesium in treating depression and especially anxiety. Calcium and glutamate are serious neurotoxins in excess (we are hypersensitive to them), and must be greatly reduced in our diets for the beneficial effect of magnesium to be observable. Malabsorption factors such as Leaky Gut Syndrome", curable using probiotics and CoQ10, must be addressed. Zinc, chromium, iodine and vanadium may be extremely helpful in protecting magnesium intracellular levels. Our future as intelligent, rational people and as technological nation is at risk to magnesium deficiency. Remember, there are no nutritional requirements (RDAs) for any psychiatricdrug, but there is for magnesium. Drugs may help patch a problem for a while,but they, by themselves, cannot sustain health and mental function. Onlynutrients can sustain health and mental function. I conclude my essay with one perfect sentence by one nearly perfect American:"Be happy and have fun." - John Wayne